| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Dubreucq, S Kambire, M Conforzi, M Metna-Laurent, A Cannich, E Soria-Gomez, E Richard, G Marsicano, F Chaoulof. Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors. Neuroscience. vol 204. 2012-07-23. PMID:21920410. |
this study has investigated the role of hypothalamic and amygdalar type-1 cannabinoid (cb1) receptors in the emotional and neuroendocrine responses to stress. |
2012-07-23 |
2023-08-12 |
mouse |
| O Valverde, M Torren. CB1 receptor-deficient mice as a model for depression. Neuroscience. vol 204. 2012-07-23. PMID:21964469. |
in the last 10 years, numerous experimental studies have revealed the participation of the endocannabinoid system in the control of emotional behavior and mood through the activation of the cb1 cannabinoid receptors. |
2012-07-23 |
2023-08-12 |
mouse |
| O Valverde, M Torren. CB1 receptor-deficient mice as a model for depression. Neuroscience. vol 204. 2012-07-23. PMID:21964469. |
considering the body of elements that acts under the control of the endocannabinoid system and the key role played by the activation of the cb1 cannabinoid receptors in the control of emotion and mood, we had proposed that genetically modified mice lacking the cb1 cannabinoid receptors could represent a genetic model for depression. |
2012-07-23 |
2023-08-12 |
mouse |
| C J Hillard, K M Weinlander, K L Stuh. Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence. Neuroscience. vol 204. 2012-07-23. PMID:22123166. |
preclinical data demonstrate that endocannabinoid signaling is an important stress buffer and modulates emotional and cognitive functions. |
2012-07-23 |
2023-08-12 |
human |
| Alejandro Higuera-Matas, Miguel Miguéns, Santiago M Coria, María Amparo Assis, Erika Borcel, Nuria del Olmo, Emilio Ambrosi. Sex-specific disturbances of the glutamate/GABA balance in the hippocampus of adult rats subjected to adolescent cannabinoid exposure. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245681. |
the endogenous cannabinoid system regulates central nervous system development and cannabinoid exposure during adolescence has been linked to several alterations to hippocampal-dependent processes such as cognition and emotion, which rely on intact glutamatergic and gabaergic systems. |
2012-07-23 |
2023-08-12 |
rat |
| Alejandro Higuera-Matas, Miguel Miguéns, Santiago M Coria, María Amparo Assis, Erika Borcel, Nuria del Olmo, Emilio Ambrosi. Sex-specific disturbances of the glutamate/GABA balance in the hippocampus of adult rats subjected to adolescent cannabinoid exposure. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245681. |
these observations may provide important insight into the neuronal basis of the well-documented alterations in cognitive and emotional processes induced by adolescent cannabinoid exposure. |
2012-07-23 |
2023-08-12 |
rat |
| M N Hil. Introduction to the special issue on stress, emotional behavior, and the endocannabinoid system: a decade of research. Neuroscience. vol 204. 2012-07-23. PMID:22348586. |
introduction to the special issue on stress, emotional behavior, and the endocannabinoid system: a decade of research. |
2012-07-23 |
2023-08-12 |
Not clear |
| M N Hil. Introduction to the special issue on stress, emotional behavior, and the endocannabinoid system: a decade of research. Neuroscience. vol 204. 2012-07-23. PMID:22348586. |
this article is part of a special issue entitled:stress, emotional behavior, and the endocannabinoid system. |
2012-07-23 |
2023-08-12 |
Not clear |
| Christian A Cea-del Rio, Chris J McBain, Kenneth A Pelke. An update on cholinergic regulation of cholecystokinin-expressing basket cells. The Journal of physiology. vol 590. issue 4. 2012-06-26. PMID:22199168. |
one subtype of interneuron, the cholecystokinin-expressing basket cell (cckbc), is particularly well suited to integrate and impart emotional features of an animal's physiological state to principal cell entrainment through the inhibitory network as cckbcs are highly susceptible to neuromodulation by local and subcortically generated signals commonly associated with 'mood' such as cannabinoids, serotonin and acetylcholine. |
2012-06-26 |
2023-08-12 |
Not clear |
| Antonia Serrano, Loren H Parson. Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. Pharmacology & therapeutics. vol 132. issue 3. 2012-03-01. PMID:21798285. |
endocannabinoid signaling is known to modulate neural development, immune function, metabolism, synaptic plasticity and emotional state. |
2012-03-01 |
2023-08-12 |
Not clear |
| Antonia Serrano, Loren H Parson. Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. Pharmacology & therapeutics. vol 132. issue 3. 2012-03-01. PMID:21798285. |
accumulating evidence also implicates brain endocannabinoid signaling in the etiology of drug addiction which is characterized by compulsive drug seeking, loss of control in limiting drug intake, emergence of a negative emotional state in the absence of drug use and a persistent vulnerability toward relapse to drug use during protracted abstinence. |
2012-03-01 |
2023-08-12 |
Not clear |
| Boris B Gorzalka, Matthew N Hil. Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 7. 2012-02-08. PMID:21111017. |
specifically, a deficiency in endocannabinoid signaling is sufficient to produce a "depressive-like" phenotype at the preclinical level (including changes in rewarding, emotional and cognitive behavior and biological changes such as increased hpa axis activity, impaired stress adaptation, reduced neurogenesis and altered serotonin negative feedback), and capable of inducing symptoms of depression in humans at a clinical level. |
2012-02-08 |
2023-08-12 |
Not clear |
| Matthias Klugmann, Viktoria Klippenstein, F Markus Leweke, Rainer Spanagel, Miriam Schneide. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. The international journal of neuropsychopharmacology. vol 14. issue 4. 2011-12-16. PMID:21211107. |
recent evidence suggests an involvement of the endocannabinoid system in the regulation of emotional behaviour and ethanol intake. |
2011-12-16 |
2023-08-12 |
rat |
| Matthew N Hill, Cecilia J Hillard, Bruce S McEwe. Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 9. 2011-12-09. PMID:21263035. |
alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid cb1 receptor-deficient mice parallel the effects of chronic stress. |
2011-12-09 |
2023-08-12 |
mouse |
| Matthew N Hill, Cecilia J Hillard, Bruce S McEwe. Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 9. 2011-12-09. PMID:21263035. |
collectively, these data demonstrate that loss of cannabinoid cb(1) receptor signaling produces a chronic stress-like phenotype under basal conditions and provide a putative neural substrate that may subserve the changes in emotional behavior seen following disruption of cb(1) receptor signaling. |
2011-12-09 |
2023-08-12 |
mouse |
| Matthias Klugmann, Anja Goepfrich, Chris M Friemel, Miriam Schneide. AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21808613. |
the endocannabinoid (ecb) system is strongly involved in the regulation of cognitive processing and emotional behavior and evidence indicates that ecb signaling might affect these behavioral abilities by modulations of prefrontal cortical functions. |
2011-11-10 |
2023-08-12 |
human |
| Ana Luisa Terzian, Filippo Drago, Carsten T Wotjak, Vincenzo Mical. The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21887137. |
the dopamine and cannabinoid interaction in the modulation of emotions and cognition: assessing the role of cannabinoid cb1 receptor in neurons expressing dopamine d1 receptors. |
2011-11-10 |
2023-08-12 |
mouse |
| Ana Luisa Terzian, Filippo Drago, Carsten T Wotjak, Vincenzo Mical. The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21887137. |
although cannabinoid cb1 receptors (cb1rs) are densely expressed in neurons expressing dopamine d1 receptors (d1rs), it is not fully understood to what extent they modulate emotional behaviors. |
2011-11-10 |
2023-08-12 |
mouse |
| Claudio Zanettini, Leigh V Panlilio, Mano Alicki, Steven R Goldberg, József Haller, Sevil Yasa. Effects of endocannabinoid system modulation on cognitive and emotional behavior. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21949506. |
effects of endocannabinoid system modulation on cognitive and emotional behavior. |
2011-11-10 |
2023-08-12 |
Not clear |
| Claudio Zanettini, Leigh V Panlilio, Mano Alicki, Steven R Goldberg, József Haller, Sevil Yasa. Effects of endocannabinoid system modulation on cognitive and emotional behavior. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:21949506. |
research has shown that cannabinoid drugs produce these effects by driving the brain's endogenous cannabinoid system and that this system plays a modulatory role in many cognitive and emotional processes. |
2011-11-10 |
2023-08-12 |
Not clear |