| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eduardo Loureiro-Campos, António Mateus-Pinheiro, Patrícia Patrício, Carina Soares-Cunha, Joana Silva, Vanessa Morais Sardinha, Bárbara Mendes-Pinheiro, Tiago Silveira-Rosa, Ana Verónica Domingues, Ana João Rodrigues, João Oliveira, Nuno Sousa, Nuno Dinis Alves, Luísa Pint. Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods. eLife. vol 10. 2021-12-03. PMID:34859784. |
the results herein presented demonstrate the modulatory role exerted by the ap2γ transcription factor and the relevance of hippocampal neurogenesis in the development of emotional states and memory processes. |
2021-12-03 |
2023-08-13 |
mouse |
| Ganggang Li, Shiyue Zhang, Yating Cheng, Ye Lu, Zhixia Jia, Xiaohui Yang, Shaodan Zhang, Wenxiang Guo, Lin Pe. Baicalin suppresses neuron autophagy and apoptosis by regulating astrocyte polarization in pentylenetetrazol-induced epileptic rats and PC12 cells. Brain research. vol 1774. 2021-11-29. PMID:34780748. |
in conclusion, these findings suggest that bal can prevents cognitive and emotional disorders and has antiepileptic effects in rats, which may be associated with suppresses neuron autophagy and apoptosis in the hippocampus via regulate astrocyte phenotypes. |
2021-11-29 |
2023-08-13 |
rat |
| Olga Netsyk, Hayma Hammoud, Sergiy V Korol, Zhe Jin, Atieh S Tafreshiha, Bryndis Birni. Tonic GABA-activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis. Hippocampus. vol 30. issue 11. 2021-11-26. PMID:32533811. |
the hippocampus is a medial temporal lobe structure in the brain and is widely studied for its role in memory and learning, in particular, spacial memory and emotional responses. |
2021-11-26 |
2023-08-13 |
mouse |
| Alexander K Zinsmaier, Yan Dong, Yanhua H Huan. Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens. Molecular psychiatry. 2021-11-26. PMID:33963288. |
the nucleus accumbens (nac) integrates and prioritizes different emotional and motivational inputs to the reward system by processing convergent glutamatergic projections from the medial prefrontal cortex, basolateral amygdala, ventral hippocampus, and other limbic and paralimbic brain regions. |
2021-11-26 |
2023-08-13 |
Not clear |
| Richard Salvi, Kelly Radziwon, Senthilvelan Manohar, Ben Auerbach, Dalian Ding, Xiaopeng Liu, Condon Lau, Yu-Chen Chen, Guang-Di Che. Review: Neural Mechanisms of Tinnitus and Hyperacusis in Acute Drug-Induced Ototoxicity. American journal of audiology. vol 30. issue 3S. 2021-11-24. PMID:33465315. |
functional imaging studies indicated that salicylate increased spontaneous activity and enhanced functional connectivity between structures in the central auditory pathway and regions of the brain associated with arousal (reticular formation), emotion (amygdala), memory/spatial navigation (hippocampus), motor planning (cerebellum), and motor control (caudate/putamen). |
2021-11-24 |
2023-08-13 |
Not clear |
| Ajisha Yesudhas, Risna Kanjirassery Radhakrishnan, Aishwarya Sukesh, Sowbarnika Ravichandran, Nivethitha Manickam, Mahesh Kandasam. BOTOX® counteracts the innate anxiety-related behaviours in correlation with increased activities of key antioxidant enzymes in the hippocampus of ageing experimental mice. Biochemical and biophysical research communications. vol 569. 2021-11-22. PMID:34229123. |
this study strongly supports that botox® could be implemented to prevent or treat anxiety and hippocampal oxidative stress resulting from ageing, emotional and mood disorders. |
2021-11-22 |
2023-08-13 |
mouse |
| Mark G Packard, Ty Gadberry, Jarid Goodma. Neural systems and the emotion-memory link. Neurobiology of learning and memory. vol 185. 2021-11-22. PMID:34418544. |
within the context of a multiple systems approach to memory focusing on selective roles for the hippocampus and dorsolateral striatum in cognitive and habit memory, the original studies indicating that robust emotional arousal can bias animals and humans toward the predominant use of habit memory are reviewed. |
2021-11-22 |
2023-08-13 |
human |
| Shaolin Yang, Kuei Y Tsen. Maturation of Corticolimbic Functional Connectivity During Sensitive Periods of Brain Development. Current topics in behavioral neurosciences. 2021-11-19. PMID:34386969. |
in this chapter, we first review how key cellular and circuit level changes during adolescence dictate the development of the prefrontal cortex and its capacity to integrate contextual and emotional information from the ventral hippocampus and the amygdala. |
2021-11-19 |
2023-08-13 |
Not clear |
| Il Bin Kim, Seon-Cheol Par. The Entorhinal Cortex and Adult Neurogenesis in Major Depression. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34769155. |
this review highlights recent findings suggesting neural circuitry-regulated neurogenesis, with a focus on the potential role of the entorhinal cortex in hippocampal neurogenesis in depression-related cognitive and emotional phenotypes. |
2021-11-18 |
2023-08-13 |
Not clear |
| Veronica Castelnovo, Elisa Canu, Maria Antonietta Magno, Silvia Basaia, Nilo Riva, Barbara Poletti, Vincenzo Silani, Massimo Filippi, Federica Agost. Impaired recognition of disgust in amyotrophic lateral sclerosis is related to basal ganglia involvement. NeuroImage. Clinical. vol 32. 2021-11-17. PMID:34537684. |
in the present study we investigated emotion recognition in pure motor amyotrophic lateral sclerosis (als) patients and its relationship with the integrity of basal ganglia, hippocampus and amygdala. |
2021-11-17 |
2023-08-13 |
human |
| Fotini-Heleni Karachaliou, Kyriaki Karavanaki, Aristofania Simatou, Eleni Tsintzou, Nikitas S Skarakis, Christina Kanaka-Gatenbei. Association of growth hormone deficiency (GHD) with anxiety and depression: experimental data and evidence from GHD children and adolescents. Hormones (Athens, Greece). vol 20. issue 4. 2021-11-16. PMID:34195937. |
the growth hormone/insulin-like growth factor 1 (gh/igf1) axis seems to exert a regulatory effect on brain function and neurogenesis, especially in the hippocampus, a brain region associated with mental and emotional disorders, such as depression and anxiety. |
2021-11-16 |
2023-08-13 |
Not clear |
| Mizuki Uchida, Yukihiro Noda, Sho Hasegawa, Hirotake Hida, Masayuki Taniguchi, Akihiro Mouri, Akira Yoshimi, Toshitaka Nabeshima, Kiyofumi Yamada, Tomomi Aida, Kohichi Tanaka, Norio Ozak. Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice. Neurochemistry international. vol 150. 2021-11-11. PMID:34481039. |
at 8 weeks of age, they showed impairments in cognitive or emotional behaviors; dysfunction of glutamatergic neurotransmission (increased expressions of glast, glt-1, or gfap protein, and decreased ability of glutamate release) in the cortex or hippocampus; morphological changes (decreased cell size in the cortex and thickness of the pyramidal neuronal layer of the ca1 area in the hippocampus). |
2021-11-11 |
2023-08-13 |
mouse |
| C D Walker, Cynthia M Kuhn, M-L Rishe. The effects of peri-adolescent alcohol use on the developing hippocampus. International review of neurobiology. vol 160. 2021-11-11. PMID:34696875. |
the hippocampus which is important for the integration of emotion, reward, homeostasis, and memory is particularly vulnerable to the neurotoxic effects of alcohol. |
2021-11-11 |
2023-08-13 |
Not clear |
| Sayaka Wada, Motoyasu Honma, Yuri Masaoka, Masaki Yoshida, Nobuyoshi Koiwa, Haruko Sugiyama, Natsuko Iizuka, Satomi Kubota, Yumika Kokudai, Akira Yoshikawa, Shotaro Kamijo, Sawa Kamimura, Masahiro Ida, Kenjiro Ono, Hidetoshi Onda, Masahiko Izumizak. Volume of the right supramarginal gyrus is associated with a maintenance of emotion recognition ability. PloS one. vol 16. issue 7. 2021-11-10. PMID:34293003. |
we measured the gray matter volume of 18 regions of interest including the bilateral precuneus, supramarginal gyrus, orbital gyrus, straight gyrus, superior temporal sulcus, inferior frontal gyrus, insular cortex, amygdala, and hippocampus, which have been associated with social function and emotion recognition. |
2021-11-10 |
2023-08-13 |
human |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
this study examined whether a low dose of mamph can induce conditioned taste aversion (cta) learning, or can increase plasma corticosterone levels, neural activity, and neural plasticity in the medial prefrontal cortex (mpfc) (responsible for cognitive function), the nucleus accumbens (nac) and the amygdala (related to rewarding and aversive emotion), and the hippocampus (responsible for spatial learning). |
2021-11-10 |
2023-08-13 |
rat |
| Shi-Xiao Peng, Yue-Ying Wang, Min Zhang, Yan-Yu Zang, Dan Wu, Jingwen Pei, Yansong Li, Jiapei Dai, Xiaoyun Guo, Xingguang Luo, Ning Zhang, Jian-Jun Yang, Chen Zhang, Xiang Gao, Na Liu, Yun Stone Sh. SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder. Scientific reports. vol 11. issue 1. 2021-11-09. PMID:34099816. |
tarp γ-8 (also known as cacng8) preferentially expresses in the hippocampus, cortex and subcortical regions that are critical for emotion generation indicating its association with psychiatric disorders. |
2021-11-09 |
2023-08-13 |
mouse |
| Andrzej Sokołowski, Carmen Morawetz, Monika Folkierska-Żukowska, Wojciech Draga. Brain Activation During Cognitive Reappraisal Depending on Regulation Goals and Stimulus Valence. Social cognitive and affective neuroscience. 2021-11-08. PMID:34746952. |
decreasing emotions was associated with stronger involvement of the dorsolateral prefrontal cortex, while increasing with activation of amygdala and hippocampus. |
2021-11-08 |
2023-08-13 |
Not clear |
| Wenxin Zhang, Xueqing Chai, Xiaolin Li, Xiaoyue Tan, Zhuo Yan. Legumain knockout improves repeated corticosterone injection-induced depression-like emotional and cognitive deficits. Behavioural brain research. vol 413. 2021-11-04. PMID:34265317. |
in conclusion, our results demonstrated that legumain knockout up-regulated expression of the gr by reducing protein expression in the mapk signaling pathway, thereby improving hippocampal synaptic plasticity as well as the emotional and cognitive impairment of model mice. |
2021-11-04 |
2023-08-13 |
mouse |
| Ellen G Fraser, Ty Makarowski, Robert J McDonal. Perforant path inputs to hippocampal subfields predict heterogeneous AMPA receptor subunit expression following rapid new spatial learning in a novel context. The European journal of neuroscience. vol 54. issue 8. 2021-11-03. PMID:34214189. |
these latter results may be indicative of pattern separation in the dentate gyrus and emotional triage functions of the ventral hippocampus. |
2021-11-03 |
2023-08-13 |
rat |
| Sayad Kocahan, Kubra Akillioglu, Leman Sencar, Leyla Sahin, Ozge Selin Cevik, Eylem Taskin, Celal Guven, Ayper Boga, Sait Pola. Living with female rats exposed to restraint stress during pregnancy caused depressive-like behavior in male rats and stress-induced apoptosis. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 7. 2021-11-02. PMID:34228828. |
the purpose of this study investigates emotional behavior and hippocampal apoptosis alterations of the male live with a postpartum depressed female. |
2021-11-02 |
2023-08-13 |
rat |