| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eun Chae Lee, Dong-Yong Hong, Dong-Hun Lee, Sang-Won Park, Ji Young Lee, Ji Hun Jeong, Eun-Young Kim, Hyung-Min Chung, Ki-Sung Hong, Se-Pill Park, Man Ryul Lee, Jae Sang O. Inflammation and Rho-Associated Protein Kinase-Induced Brain Changes in Vascular Dementia. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203655. |
thus, we revealed that rock pathway activation loosens the tight junction of the blood-brain barrier and increases the influx of inflammatory cytokines into the hippocampal region, leading to neuronal death and causing cognitive and emotional dysfunction. |
2022-02-25 |
2023-08-13 |
mouse |
| Radu Lefter, Roxana Oana Cojocariu, Alin Ciobica, Ioana-Miruna Balmus, Ioannis Mavroudis, Anna Ki. Interactions between Sleep and Emotions in Humans and Animal Models. Medicina (Kaunas, Lithuania). vol 58. issue 2. 2022-02-25. PMID:35208598. |
we found that a strong modulatory interaction between sleep processes and emotional states resides on the activity of several key brain structures, such as the amygdala, prefrontal cortex, hippocampus, and brainstem nuclei. |
2022-02-25 |
2023-08-13 |
human |
| Seyed Mehdi Vatandoust, Gholam Hossein Meftah. The Effect of Sericin on the Cognitive Impairment, Depression, and Anxiety Caused by Learned Helplessness in Male Mice. Journal of molecular neuroscience : MN. 2022-02-15. PMID:35165850. |
learned helplessness (lh) induces cognitive and emotional abnormalities via alteration of synaptic and apoptotic markers in the hippocampus. |
2022-02-15 |
2023-08-13 |
mouse |
| Niccolò Zovetti, Cinzia Perlini, Paolo Brambilla, Marcella Bellan. Childhood adversities and bipolar disorder: a neuroimaging focus. Epidemiology and psychiatric sciences. vol 31. 2022-02-03. PMID:35109957. |
alterations in these regions of the brain of patients with bd are possibly due to the effect of stress produced by cas, being hippocampus part of the hypothalamus-pituitary-adrenal axis and thalamus together with amygdala filtering sensory information and regulating emotional responses. |
2022-02-03 |
2023-08-13 |
Not clear |
| Samantha K Saland, Kathrin Wilczak, Edward Voss, TuKiet T Lam, Mohamed Kabba. Sex- and estrous-cycle dependent dorsal hippocampal phosphoproteomic changes induced by low-dose ketamine. Scientific reports. vol 12. issue 1. 2022-02-03. PMID:35110693. |
numerous emotional and cognitive processes mediated by the hippocampus present differences between sexes and can be markedly influenced by hormonal status in males and females of several species. |
2022-02-03 |
2023-08-13 |
rat |
| Julia Maruani, Pierre A Geoffro. Multi-Level Processes and Retina-Brain Pathways of Photic Regulation of Mood. Journal of clinical medicine. vol 11. issue 2. 2022-01-21. PMID:35054142. |
this review proposes two distinct retina-brain pathways of light effects on mood: (i) a suprachiasmatic nucleus (scn)-dependent pathway with light effect on mood via the synchronization of biological rhythms, and (ii) a scn-independent pathway with light effects on mood through modulation of the homeostatic process of sleep, alertness and emotion regulation: (1) light directly inhibits brain areas promoting sleep such as the ventrolateral preoptic nucleus (vlpo), and activates numerous brain areas involved in alertness such as, monoaminergic areas, thalamic regions and hypothalamic regions including orexin areas; (2) moreover, light seems to modulate mood through orexin-, serotonin- and dopamine-dependent pathways; (3) in addition, light activates brain emotional processing areas including the amygdala, the nucleus accumbens, the perihabenular nucleus, the left hippocampus and pathways such as the retina-ventral lateral geniculate nucleus and intergeniculate leaflet-lateral habenula pathway. |
2022-01-21 |
2023-08-13 |
Not clear |
| Csilla Lea Fazekas, Adrienn Szabó, Bibiána Török, Krisztina Bánrévi, Pedro Correia, Tiago Chaves, Stéphanie Daumas, Dóra Zelen. A New Player in the Hippocampus: A Review on VGLUT3+ Neurons and Their Role in the Regulation of Hippocampal Activity and Behaviour. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35054976. |
this hippocampal glutamatergic network plays a pivotal role in several important processes (e.g., learning and memory, emotions, epilepsy, cardiovascular regulation). |
2022-01-21 |
2023-08-13 |
mouse |
| Angelica Lindlö. The Vulnerability of the Developing Brain: Analysis of Highly Expressed Genes in Infant C57BL/6 Mouse Hippocampus in Relation to Phenotypic Annotation Derived From Mutational Studies. Bioinformatics and biology insights. vol 16. 2022-01-13. PMID:35023907. |
the hippocampus has been shown to have a major role in learning and memory, but also to participate in the regulation of emotions. |
2022-01-13 |
2023-08-13 |
mouse |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
therefore, we examined the effect of ventral hippocampus (vh) disinhibition in male rats on fear conditioning and salience modulation, as reflected by latent inhibition (li), in a conditioned emotional response procedure (cer). |
2022-01-04 |
2023-08-13 |
rat |
| Wei Jing, Tongmei Zhang, Jiaying Liu, Xian Huang, Quntao Yu, Hongyan Yu, Qingping Zhang, Hao Li, Manfei Deng, Ling-Qiang Zhu, Huiyun Du, Youming L. A circuit of COCH neurons encodes social-stress-induced anxiety via MTF1 activation of Cacna1h. Cell reports. vol 37. issue 13. 2021-12-29. PMID:34965426. |
the hippocampus is a temporal lobe structure critical for cognition, such as learning, memory, and attention, as well as emotional responses. |
2021-12-29 |
2023-08-13 |
Not clear |
| Qian Li, Hong Li, Xiuting Yao, Conghui Wang, Haiqing Liu, Dan Xu, Chenxi Yang, Hong Zhuang, Yu Xiao, Rui Liu, Sinuo Shen, Shaoyang Zhou, Chenge Fu, Yifan Wang, Gaojun Teng, Lijie Li. Stress Response and Hearing Loss Differentially Contribute to Dynamic Alterations in Hippocampal Neurogenesis and Microglial Reactivity in Mice Exposed to Acute Noise Exposure. Frontiers in neuroscience. vol 15. 2021-12-27. PMID:34955715. |
given the pervasiveness of noise pollution in modern society and the important implications of either microglial activity or hippocampal neurogenesis for cognitive and emotional function, this study was designed to investigate how microglial status and hippocampal neurogenesis change over time following acoustic exposure and to analyze the possible roles of the noise exposure-induced stress response and hearing loss in these changes. |
2021-12-27 |
2023-08-13 |
mouse |
| Natalia V Gulyaeva, Mikhail V Onufriev, Yulia V Moiseev. Ischemic Stroke, Glucocorticoids, and Remote Hippocampal Damage: A Translational Outlook and Implications for Modeling. Frontiers in neuroscience. vol 15. 2021-12-27. PMID:34955730. |
patients-at-risk with high cortisol prone to delayed remote hippocampal damage should be monitored since hippocampal dysfunction may be the basis for development of post-stroke cognitive and emotional disturbances, as well as epilepsy. |
2021-12-27 |
2023-08-13 |
Not clear |
| Jun-Ying Wang, Yue Zhang, Yu Chen, Yu Wang, Shao-Yuan Li, Yi-Fei Wang, Zi-Xuan Zhang, Jinling Zhang, Peijing Ron. Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway. Journal of neuroinflammation. vol 18. issue 1. 2021-12-18. PMID:34920740. |
the anti-inflammatory signal of vagus nerve is mediated by α7 nicotinic acetylcholine receptor (α7nachr), and the hippocampus, the region with the most distribution of α7nachr, regulates emotions. |
2021-12-18 |
2023-08-13 |
rat |
| Mkp Joyce, L G Marshall, S L Banik, J Wang, D Xiao, J G Bunce, H Barba. Pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic Reuniens Nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021-12-14. PMID:34903572. |
pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic reuniens nucleus. |
2021-12-14 |
2023-08-13 |
mouse |
| Mkp Joyce, L G Marshall, S L Banik, J Wang, D Xiao, J G Bunce, H Barba. Pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic Reuniens Nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021-12-14. PMID:34903572. |
convergent pathways from hippocampus, a25 and amygdala in re position it to flexibly coordinate activity for memory, cognition, and emotional context, which are disrupted in several psychiatric and neurologic diseases in humans. |
2021-12-14 |
2023-08-13 |
mouse |
| Rachael Dixon-Melvin, Khadijah Shanazz, Rebecca Nalloor, Kristopher M Bunting, Almira Vazdarjanov. Emotional state alters encoding of long-term spatial episodic memory. Neurobiology of learning and memory. vol 187. 2021-12-11. PMID:34848328. |
combined, the findings reject the tested hypothesis and suggest that a negative emotional state is encoded in the hippocampus as part of the long-term memory of episodic events that lack explicit emotion-inducing stimuli. |
2021-12-11 |
2023-08-13 |
human |
| Paulina Fałek, Artur Fałek, Monika Kager, Richard Kager, Piotr Walkowicz, Marcin Kubiak, Elżbieta Starosławska, Franciszek Burda. Information impact on synaptic arousal and formation of permanent memory trace. Folia medica Cracoviensia. vol 61. issue 3. 2021-12-09. PMID:34882662. |
the influence of emotions on memory is obvious, largely determined by the close cooperation of the amygdala (responsible for emotions) and the hippocampus (memory processes). |
2021-12-09 |
2023-08-13 |
Not clear |
| Chunliang Feng, Ruolei Gu, Ting Li, Li Wang, Zhixing Zhang, Wenbo Luo, Simon B Eickhof. Separate neural networks of implicit emotional processing between pictures and words: A coordinate-based meta-analysis of brain imaging studies. Neuroscience and biobehavioral reviews. vol 131. 2021-12-07. PMID:34562542. |
specifically, implicit negative picture processing (35 experiments, 393 foci, and 932 subjects) engages the bilateral amygdala, left hippocampus, fusiform gyri, and right insula, which are mainly located in the subcortical network and visual network associated with bottom-up emotional responses. |
2021-12-07 |
2023-08-13 |
human |
| Susanne Moosecker, Anna Pissioti, Este Leidmaa, Mazen R Harb, Chrysoula Dioli, Nils C Gassen, Shuang Yu, Mary Gazea, Caterina Catania, Elmira Anderzhanova, Alexandre V Patchev, Claudia Kühne, Rainer Stoffel, Ioannis Sotiropoulos, Osborne F X Almeid. Brain Expression, Physiological Regulation and Role in Motivation and Associative Learning of Peroxisome Proliferator-activated Receptor γ. Neuroscience. vol 479. 2021-12-07. PMID:34762981. |
this study aimed to (i) map pparγ expression in rodent brain areas, involved in the regulation of cognitive, motivational, and emotional functions, (ii) examine the regulation of central pparγ by physiological variables (age, sex, obesity); (iii) chemotypically identify pparγ-expressing cells in the frontal cortex (fc) and hippocampus (hp); (iv) study whether activation of pparγ by pioglitazone (pio) in fc and hp cells can induce target gene expression; and (v) demonstrate the impact of activated pparγ on learning behavior and motivation. |
2021-12-07 |
2023-08-13 |
Not clear |
| Eduardo Loureiro-Campos, António Mateus-Pinheiro, Patrícia Patrício, Carina Soares-Cunha, Joana Silva, Vanessa Morais Sardinha, Bárbara Mendes-Pinheiro, Tiago Silveira-Rosa, Ana Verónica Domingues, Ana João Rodrigues, João Oliveira, Nuno Sousa, Nuno Dinis Alves, Luísa Pint. Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods. eLife. vol 10. 2021-12-03. PMID:34859784. |
ap2γ deficiency promotes downregulation of hippocampal glutamatergic neurogenesis, altering the ontogeny of emotional and memory behaviors associated with hippocampus formation. |
2021-12-03 |
2023-08-13 |
mouse |