Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Muriel Koehl, Elodie Ladevèze, Caterina Catania, Daniela Cota, Djoher Nora Abrou. Inhibition of mTOR signaling by genetic removal of p70 S6 kinase 1 increases anxiety-like behavior in mice. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33723223. |
we found that deleting s6k1 leads to a robust anxious phenotype concomitant with associative learning deficits; these symptoms are associated with a reduction of adult neurogenesis and neuronal atrophy in the hippocampus. |
2021-06-28 |
2023-08-13 |
mouse |
Derick H Lindquis. Emotion in motion: A three-stage model of aversive classical conditioning. Neuroscience and biobehavioral reviews. vol 115. 2021-06-21. PMID:32416126. |
with respect to associative learning, emotional, contextual, and sensorimotor conditioning is established, maintained, and expressed by the amygdala, hippocampus, and cerebellum, respectively. |
2021-06-21 |
2023-08-13 |
Not clear |
Rachel C Cole, Eliot Hazeltine, Timothy B Weng, Conner Wharff, Lyndsey E DuBose, Phillip Schmid, Gardar Sigurdsson, Vincent A Magnotta, Gary L Pierce, Michelle W Vos. Cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults. Hippocampus. vol 30. issue 2. 2021-06-08. PMID:31461198. |
cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults. |
2021-06-08 |
2023-08-13 |
Not clear |
Soomaayeh Heysieattalab, Ka-Hung Lee, Yan Liu, Yubin Wang, Michael R Foy, Xiaoning Bi, Michel Baudr. Impaired cerebellar plasticity and eye-blink conditioning in calpain-1 knock-out mice. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30735788. |
our results indicate that calpain-1 plays critical roles in multiple forms of synaptic plasticity and associative learning in both hippocampus and cerebellum. |
2021-04-12 |
2023-08-13 |
mouse |
Sophie Menneson, Yann Serrand, Regis Janvier, Virginie Noirot, Pierre Etienne, Nicolas Coquery, David Val-Laille. Regular exposure to a Citrus-based sensory functional food ingredient alleviates the BOLD brain responses to acute pharmacological stress in a pig model of psychosocial chronic stress. PloS one. vol 15. issue 12. 2021-02-09. PMID:33370353. |
pharmacological stress with synacthen injection resulted in an increased activity in several brain regions associated with arousal, associative learning (hippocampus) and cognition (cingulate cortex) in chronically stressed animals. |
2021-02-09 |
2023-08-13 |
Not clear |
Yuya Sakimoto, Shogo Sakat. The role of the hippocampal theta rhythm in non-spatial discrimination and associative learning task. Neuroscience and biobehavioral reviews. vol 110. 2021-01-11. PMID:30261198. |
the role of the hippocampal theta rhythm in non-spatial discrimination and associative learning task. |
2021-01-11 |
2023-08-13 |
Not clear |
Benjamin Spurny, Rene Seiger, Philipp Moser, Thomas Vanicek, Murray B Reed, Eva Heckova, Paul Michenthaler, Alim Basaran, Gregor Gryglewski, Manfred Klöbl, Siegfried Trattnig, Siegfried Kasper, Wolfgang Bogner, Rupert Lanzenberge. Hippocampal GABA levels correlate with retrieval performance in an associative learning paradigm. NeuroImage. vol 204. 2020-11-27. PMID:31606475. |
hippocampal gaba levels correlate with retrieval performance in an associative learning paradigm. |
2020-11-27 |
2023-08-13 |
human |
Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
particularly, cocaine sensitization in rats enhanced synaptic plasticity within the hippocampus, an important brain region for the associative learning processes underlying drug addiction. |
2020-10-07 |
2023-08-13 |
rat |
Kristin M Scaplen, Rohan N Ramesh, Negin Nadvar, Omar J Ahmed, Rebecca D Burwel. Inactivation of the Lateral Entorhinal Area Increases the Influence of Visual Cues on Hippocampal Place Cell Activity. Frontiers in systems neuroscience. vol 11. 2020-10-01. PMID:28611603. |
the hippocampus is important for both navigation and associative learning. |
2020-10-01 |
2023-08-13 |
Not clear |
Sanoara Mazid, Baila S Hall, Shannon C Odell, Khalifa Stafford, Andreina D Dyer, Tracey A Van Kempen, Jane Selegean, Bruce S McEwen, Elizabeth M Waters, Teresa A Milne. Sex differences in subcellular distribution of delta opioid receptors in the rat hippocampus in response to acute and chronic stress. Neurobiology of stress. vol 5. 2020-09-29. PMID:27981195. |
drug addiction requires associative learning processes that critically involve hippocampal circuits, including the opioid system. |
2020-09-29 |
2023-08-13 |
rat |
Simon Henin, Anita Shankar, Nicholas Hasulak, Daniel Friedman, Patricia Dugan, Lucia Melloni, Adeen Flinker, Cansu Sarac, May Fang, Werner Doyle, Thomas Tcheng, Orrin Devinsky, Lila Davachi, Anli Li. Hippocampal gamma predicts associative memory performance as measured by acute and chronic intracranial EEG. Scientific reports. vol 9. issue 1. 2020-07-31. PMID:30679734. |
we utilized an associative learning paradigm in 5 patients with traditional ieeg and 3 patients with chronic ieeg, and found increased hippocampal gamma (60-100 hz) sustained at 1.3-1.5 seconds during encoding in successful versus failed trials in surgical patients, with similar results in our rns system patients (1.4-1.6 seconds). |
2020-07-31 |
2023-08-13 |
human |
Kazuki Okamoto, Yuji Ikegay. Recurrent connections between CA2 pyramidal cells. Hippocampus. vol 29. issue 4. 2020-05-19. PMID:30588702. |
recurrent excitatory synapses have theoretically been shown to play roles in memory storage and associative learning and are well described to occur in the ca3 region of the hippocampus. |
2020-05-19 |
2023-08-13 |
mouse |
Vanessa Vieites, Shannon M Pruden, Anna Shusterman, Bethany C Reeb-Sutherlan. Using hippocampal-dependent eyeblink conditioning to predict individual differences in spatial reorientation strategies in 3- to 6-year-olds. Developmental science. vol 23. issue 1. 2020-03-23. PMID:31125469. |
the hippocampus is a subcortical structure in the medial temporal lobe involved in cognitive functions such as spatial navigation and reorientation, episodic memory, and associative learning. |
2020-03-23 |
2023-08-13 |
Not clear |
Eun-Young Lee, Michael R Flynn, Guangwei Du, Mechelle M Lewis, Lan Kong, Jeff D Yanosky, Richard B Mailman, Xuemei Huan. Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders. Toxicological sciences : an official journal of the Society of Toxicology. vol 168. issue 2. 2020-03-12. PMID:30629252. |
recent studies in mn-exposed animals revealed mn accumulation in the hippocampus, the presence of aβ diffuse plaques, and deficits in associative learning, the latter being hallmarks of alzheimer's disease (ad) or related disorders. |
2020-03-12 |
2023-08-13 |
human |
Matthew Randesi, Natalina H Contoreggi, Yan Zhou, Batsheva R Rubin, Julia R Bellamy, Fangmin Yu, Jason D Gray, Bruce S McEwen, Teresa A Milner, Mary Jeanne Kree. Sex Differences in Neuroplasticity- and Stress-Related Gene Expression and Protein Levels in the Rat Hippocampus Following Oxycodone Conditioned Place Preference. Neuroscience. vol 410. 2020-01-31. PMID:31071414. |
anatomical analysis of the hippocampus from these rats unveiled sex differences in the opioid system in a way that would support excitation and opiate associative learning processes especially in females. |
2020-01-31 |
2023-08-13 |
rat |
Hilary K Lambert, Matthew Peverill, Kelly A Sambrook, Maya L Rosen, Margaret A Sheridan, Katie A McLaughli. Altered development of hippocampus-dependent associative learning following early-life adversity. Developmental cognitive neuroscience. vol 38. 2020-01-13. PMID:31276941. |
broad associative learning difficulties may be a functional consequence of the toxic effects of early-life stress on hippocampal and fronto-parietal cortical development. |
2020-01-13 |
2023-08-13 |
human |
Gould, Tanapat, Hastings, Shor. Neurogenesis in adulthood: a possible role in learning. Trends in cognitive sciences. vol 3. issue 5. 2019-11-20. PMID:10322475. |
contemporary theories of hippocampal function include an important role for this brain region in associative learning. |
2019-11-20 |
2023-08-12 |
Not clear |
S. Laroche, C. Redini-Del Negro, M. P. Clements, M. A. Lync. Long-term Activation of Phosphoinositide Turnover Associated with Increased Release of Amino Acids in the Dentate Gyrus and Hippocampus Following Classical Conditioning in the Rat. The European journal of neuroscience. vol 2. issue 6. 2019-11-20. PMID:12106023. |
it is suggested that a long-lasting presynaptic activation of inositol lipid metabolism may contribute to the learning-dependent increase in the capacity of hippocampal terminals to release transmitter and hence to the maintenance of a neurochemical trace which may, at least in part, underlie lasting changes in synaptic function built up during associative learning. |
2019-11-20 |
2023-08-12 |
rat |
Agnès Gruart, Carla Sciarretta, Mauricio Valenzuela-Harrington, José M Delgado-García, Liliana Minichiell. Mutation at the TrkB PLC{gamma}-docking site affects hippocampal LTP and associative learning in conscious mice. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 1. 2019-11-20. PMID:17272652. |
mutation at the trkb plc{gamma}-docking site affects hippocampal ltp and associative learning in conscious mice. |
2019-11-20 |
2023-08-12 |
mouse |
Bing-Lin Zhu, Yan Long, Wei Luo, Zhen Yan, Yu-Jie Lai, Li-Ge Zhao, Wei-Hui Zhou, Yan-Jiang Wang, Lin-Lin Shen, Lu Liu, Xiao-Juan Deng, Xue-Feng Wang, Fei Sun, Guo-Jun Che. MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation. Brain : a journal of neurology. vol 142. issue 1. 2019-08-20. PMID:30596903. |
in appswe/ps1e9 mice, an animal model of alzheimer's disease, hippocampal mmp13 knockdown or intraperitoneal cl82198 administration reduced bace1 protein levels and the related amyloid-β precursor protein processing, amyloid-β load and eif4b phosphorylation, whereas spatial and associative learning and memory performances were improved. |
2019-08-20 |
2023-08-13 |
mouse |