| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P D Pravikova, M A Arssan, E A Zalivina, E M Kondaurova, E A Kulikova, I I Belokopytova, V S Naumenk. Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6 J). Vavilovskii zhurnal genetiki i selektsii. vol 28. issue 4. 2024-07-19. PMID:39027124. |
in btbr embryos, on the 14th day of prenatal development, an increase in the expression of the ngfr gene encoding the p75ntr receptor, which may lead to the activation of apoptosis, was found in the hippocampus and frontal cortex. |
2024-07-19 |
2024-07-21 |
mouse |
| Qin Wang, Baijun Qin, Han Yu, Haichun Yu, Xian Zhang, Mingfen Li, Yanying Zhou, Limei Diao, Huihua Li. Dingxian Pill Alleviates Hippocampal Neuronal Apoptosis in Epileptic Mice through TNF-α/TNFR1 signaling pathway inhibition. Journal of ethnopharmacology. 2024-07-18. PMID:39025165. |
dingxian pill alleviates hippocampal neuronal apoptosis in epileptic mice through tnf-α/tnfr1 signaling pathway inhibition. |
2024-07-18 |
2024-07-21 |
mouse |
| Na Wei, Luo-Man Zhang, Jing-Jing Xu, Sheng-Lei Li, Rui Xue, Sheng-Li Ma, Cai Li, Miao-Miao Sun, Kui-Sheng Che. Astaxanthin Rescues Memory Impairments in Rats with Vascular Dementia by Protecting Against Neuronal Death in the Hippocampus. Neuromolecular medicine. vol 26. issue 1. 2024-07-16. PMID:39014255. |
furthermore, astaxanthin treatment protected against hippocampal neuronal death and attenuated apoptosis. |
2024-07-16 |
2024-07-19 |
human |
| Ying Cui, Guang Yang, Hong Li, Jianying Sun, Xiaoman Liu, Xiaohan Xi. Reduced expression of NUPR1 alleviates epilepsy progression via attenuating ER stress. Biochemical and biophysical research communications. vol 730. 2024-07-12. PMID:38996786. |
in vitro experiments showed that the absence of nupr1 reduced the expression of atf4, chop, and cleaved caspase-12 in hippocampal neurons and inhibited the neuron apoptosis. |
2024-07-12 |
2024-07-15 |
mouse |
| Reham L Younis, Rehab M El-Gohary, Asmaa A Ghalwash, Islam Ibrahim Hegab, Maram M Ghabrial, Azza M Aboshanady, Raghad A Mostafa, Alaa H Abd El-Azeem, Eman E Farghal, Asmaa A E Belal, Haidy Khatta. Luteolin Mitigates D-Galactose-Induced Brain Ageing in Rats: SIRT1-Mediated Neuroprotection. Neurochemical research. 2024-07-10. PMID:38987448. |
additionally, luteolin treatment considerably attenuated neuronal apoptosis and upregulated hippocampal sirt1 mrna expression. |
2024-07-10 |
2024-07-13 |
rat |
| N V Bobkova, L N Chuvakova, V I Kovalev, D Y Zhdanova, A V Chaplygina, A P Rezvykh, M B Evgen'e. A Mouse Model of Sporadic Alzheimer's Disease with Elements of Major Depression. Molecular neurobiology. 2024-07-09. PMID:38980563. |
analysis of the functional significance of genes in the brain of obx mice indicates that the balance of the gaba/glutamatergic systems is disturbed with hyperactivation of the latter in the hippocampus, leading to the development of excitotoxicity and induction of apoptosis in the background of severe mitochondrial dysfunction and astrogliosis. |
2024-07-09 |
2024-07-12 |
mouse |
| Long Tao, Xiao-Xiao Li, Xin-Ru Tu, Rui Liu, Jia-Wen Xu, Yi-Li Lv, Yu-You Ya. Hippocampal Crhr1 conditional gene knockout ameliorated the depression-like behavior and pathological damage in male offspring mice caused by chronic stress during pregnancy. Behavioural brain research. 2024-07-05. PMID:38969017. |
this study showed that csdp induces depression-like behavior, hippocampal neuronal dendrite damage and apoptosis in male offspring mice. |
2024-07-05 |
2024-07-08 |
mouse |
| Long Tao, Xiao-Xiao Li, Xin-Ru Tu, Rui Liu, Jia-Wen Xu, Yi-Li Lv, Yu-You Ya. Hippocampal Crhr1 conditional gene knockout ameliorated the depression-like behavior and pathological damage in male offspring mice caused by chronic stress during pregnancy. Behavioural brain research. 2024-07-05. PMID:38969017. |
conditional gene knockout of hippocampal crhr1 in mice reduced csdp-induced depression-like behavior, hippocampal neuronal dendrite damage and apoptosis in male offspring, and counteracted the csdp-induced decreased expression of p-akt and mtor activity in male offspring hippocampus. |
2024-07-05 |
2024-07-08 |
mouse |
| Long Tao, Xiao-Xiao Li, Xin-Ru Tu, Rui Liu, Jia-Wen Xu, Yi-Li Lv, Yu-You Ya. Hippocampal Crhr1 conditional gene knockout ameliorated the depression-like behavior and pathological damage in male offspring mice caused by chronic stress during pregnancy. Behavioural brain research. 2024-07-05. PMID:38969017. |
these findings demonstrated that csdp might inhibit the akt/mtor pathway by increasing the levels of crh, leading to increased crh-mediated activation of hippocampal crhr1, thereby inducing synaptic impairment and apoptosis in hippocampal neurons, which in turn leads to depression-like behavior in offspring. |
2024-07-05 |
2024-07-08 |
mouse |
| Tahereh Ghorbandaiepour, Esmaeil Sadroddiny, Maryam Zahmatkesh, Gholamreza Hassanzade. Inhibition of hippocampal melatonin synthesis by siRNA induced learning and memory deficits in male rats. Hormones and behavior. vol 164. 2024-07-04. PMID:38964019. |
the nissl staining and immunohistochemistry of activated caspase-3 showed the neuronal loss and cell apoptosis in hippocampal tissue of the aanat-sirna group. |
2024-07-04 |
2024-07-11 |
rat |
| Zhenkun Xiong, Zhenhua Li, Xueqin Sima, Zhi Zen. Astaxanthin reduces TBPH-induced neurobehavioral deficits in mice by the ROS-ERK1/2-FOS pathway. Ecotoxicology and environmental safety. vol 281. 2024-07-04. PMID:38964056. |
the results indicate that exposure to tbph can lead to a decline in learning and memory abilities and abnormal behaviors in mice, which may be associated with oxidative stress responses and apoptosis in the hippocampus. |
2024-07-04 |
2024-07-11 |
mouse |
| Zhenkun Xiong, Zhenhua Li, Xueqin Sima, Zhi Zen. Astaxanthin reduces TBPH-induced neurobehavioral deficits in mice by the ROS-ERK1/2-FOS pathway. Ecotoxicology and environmental safety. vol 281. 2024-07-04. PMID:38964056. |
ast, through its antioxidant action, was able to significantly reduce the increase in reactive oxygen species (ros) levels induced by tbph, the increased expression of apoptosis markers, and the activation of the erk1/2-fos signaling pathway, alleviating tbph-induced apoptosis in hippocampal neurons and improving neurobehavioral outcomes. |
2024-07-04 |
2024-07-11 |
mouse |
| Dervis Dasdelen, Merve Solmaz, Rasim Mogulkoc, Abdulkerim Kasim Baltaci, Ender Erdoga. Apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (DiOHF). Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2024-06-28. PMID:38940209. |
apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (diohf). |
2024-06-28 |
2024-06-30 |
rat |
| Dervis Dasdelen, Merve Solmaz, Rasim Mogulkoc, Abdulkerim Kasim Baltaci, Ender Erdoga. Apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (DiOHF). Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2024-06-28. PMID:38940209. |
the present study aimed to determine the effect of 3',4'-dihydroxyflavonol (diohf) on apoptosis in the cerebellum and hippocampus in rats with ischemia-reperfusion. |
2024-06-28 |
2024-06-30 |
rat |
| Dervis Dasdelen, Merve Solmaz, Rasim Mogulkoc, Abdulkerim Kasim Baltaci, Ender Erdoga. Apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (DiOHF). Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2024-06-28. PMID:38940209. |
following application, the animals were sacrificed under general anesthetic by cervical dislocation, and the cerebellum and hippocampus tissues were analyzed for apoptosis. |
2024-06-28 |
2024-06-30 |
rat |
| Dervis Dasdelen, Merve Solmaz, Rasim Mogulkoc, Abdulkerim Kasim Baltaci, Ender Erdoga. Apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (DiOHF). Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2024-06-28. PMID:38940209. |
ir significantly increased hippocampus and cerebellum apoptosis activity, confirmed by hematoxylin-eosin, tunel labeling, and caspase-8 activity. |
2024-06-28 |
2024-06-30 |
rat |
| Dervis Dasdelen, Merve Solmaz, Rasim Mogulkoc, Abdulkerim Kasim Baltaci, Ender Erdoga. Apoptosis of hippocampus and cerebellum induced with brain ischemia reperfusion prevented by 3',4'-dihydroxyflavonol (DiOHF). Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2024-06-28. PMID:38940209. |
the results of the study show that increased apoptosis in the cerebellum and hippocampus tissue was inhibited by intraperitoneal diohf supplementation. |
2024-06-28 |
2024-06-30 |
rat |
| Maryam Moosavi, Roksana Soukhaklari, Saeid Bagheri-Mohammadi, Bita Firouzan, Pegah Javadpour, Rasoul Ghasem. Nanocurcumin prevents memory impairment, hippocampal apoptosis, Akt and CaMKII-α signaling disruption in the central STZ model of Alzheimer's disease in rat. Behavioural brain research. 2024-06-28. PMID:38942084. |
nanocurcumin prevents memory impairment, hippocampal apoptosis, akt and camkii-α signaling disruption in the central stz model of alzheimer's disease in rat. |
2024-06-28 |
2024-07-01 |
rat |
| Maryam Moosavi, Roksana Soukhaklari, Saeid Bagheri-Mohammadi, Bita Firouzan, Pegah Javadpour, Rasoul Ghasem. Nanocurcumin prevents memory impairment, hippocampal apoptosis, Akt and CaMKII-α signaling disruption in the central STZ model of Alzheimer's disease in rat. Behavioural brain research. 2024-06-28. PMID:38942084. |
these findings might suggest that nanocurcumin can restore memory deficit, hippocampal apoptosis as well as akt and camkii-α signaling disruption associated with brain insulin resistance. |
2024-06-28 |
2024-07-01 |
rat |
| Haojie Zhu, Hainan Pan, Yunli Fang, Hanxiao Wang, Zhuo Chen, Wenfeng Hu, Lijuan Tong, Jie Ren, Xu Lu, Chao Huan. Apoptosis-induced decline in hippocampal microglia mediates the development of depression-like behaviors in adult mice triggered by unpredictable stress during adolescence. European journal of pharmacology. 2024-06-21. PMID:38906239. |
further analysis showed that this decrease in microglia was mediated by the initial response of microglia to unpredictable stress in the dentate gyrus of the hippocampus and their subsequent apoptosis. |
2024-06-21 |
2024-06-24 |
mouse |