| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ram Prajit, Rasa Saenno, Kornrawee Suwannakot, Soraya Kaewngam, Tanaporn Anosri, Nataya Sritawan, Anusara Aranarochana, Apiwat Sirichoat, Wanassanun Pannangrong, Peter Wigmore, Jariya Umka Welba. Chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to D-galactose-induced brain aging. Biogerontology. 2024-09-19. PMID:39300009. |
chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to d-galactose-induced brain aging. |
2024-09-19 |
2024-09-22 |
rat |
| Ram Prajit, Rasa Saenno, Kornrawee Suwannakot, Soraya Kaewngam, Tanaporn Anosri, Nataya Sritawan, Anusara Aranarochana, Apiwat Sirichoat, Wanassanun Pannangrong, Peter Wigmore, Jariya Umka Welba. Chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to D-galactose-induced brain aging. Biogerontology. 2024-09-19. PMID:39300009. |
oxidative stress-induced neuronal apoptosis is primarily involved in brain aging and impaired hippocampal neurogenesis. |
2024-09-19 |
2024-09-22 |
rat |
| Ram Prajit, Rasa Saenno, Kornrawee Suwannakot, Soraya Kaewngam, Tanaporn Anosri, Nataya Sritawan, Anusara Aranarochana, Apiwat Sirichoat, Wanassanun Pannangrong, Peter Wigmore, Jariya Umka Welba. Chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to D-galactose-induced brain aging. Biogerontology. 2024-09-19. PMID:39300009. |
to elucidate the neuroprotection of chrysin on neuronal apoptosis and an impaired hippocampal neurogenesis relevant to oxidative damage in d-galactose-induced brain aging, male sprague dawley rats were allocated into vehicle control, d-galactose, chrysin, and cotreated rats. |
2024-09-19 |
2024-09-22 |
rat |
| Ram Prajit, Rasa Saenno, Kornrawee Suwannakot, Soraya Kaewngam, Tanaporn Anosri, Nataya Sritawan, Anusara Aranarochana, Apiwat Sirichoat, Wanassanun Pannangrong, Peter Wigmore, Jariya Umka Welba. Chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to D-galactose-induced brain aging. Biogerontology. 2024-09-19. PMID:39300009. |
this study demonstrates that chrysin likely attenuates brain aging induced by d-galactose by enhancing scavenging enzyme activities and reducing oxidative stress, neuronal apoptosis, and the impaired hippocampal neurogenesis. |
2024-09-19 |
2024-09-22 |
rat |
| Peihua Long, Qunfei Ma, Zhe Wang, Guanqin Wang, Jianan Jiang, Lu Ga. Genetic patterning in hippocampus of rat undergoing impaired spatial memory induced by long-term heat stress. Heliyon. vol 10. issue 17. 2024-09-19. PMID:39296065. |
it was found that the long-term heat stress impaired rats' spatial memory function due to the pathological damages and apoptosis of hippocampal neurons at the ca3 region, which is accompanied with the decrease of growth hormone level in peripheral blood. |
2024-09-19 |
2024-09-21 |
rat |
| Jie Li, Mingjie Yin, Zhen Wang, Yifei Xiong, Xuedi Fang, Hui Fan. Fingolimod alleviates type 2 diabetes associated cognitive decline by regulating autophagy and neuronal apoptosis via AMPK/mTOR pathway. Brain research. 2024-09-16. PMID:39284560. |
our results show that fty720 may exert neuroprotective effects in vivo by enhancing hippocampal autophagy and inhibiting apoptosis via the ampk/mtor signaling pathway. |
2024-09-16 |
2024-09-19 |
mouse |
| Hui Li, Meng Ge, Bofan Lu, Wei Wang, Yujuan Fu, Lili Jiao, Wei W. Ginsenosides modulate hypothalamic-pituitary-adrenal function by inhibiting FKBP51 on glucocorticoid receptor to ameliorate depression in mice exposed to chronic unpredictable mild stress. Phytotherapy research : PTR. 2024-09-15. PMID:39278841. |
depressed mice treated with pg demonstrated notable improvements: the rate of weight loss was reduced, sucrose preference and open-field activity were enhanced, and the rate of apoptosis in hippocampal cells was decreased. |
2024-09-15 |
2024-09-18 |
mouse |
| Jiantao Zhang, Jun Han, Nan Li, Wenli Zho. Deciphering the Protective Role of HIF-1α Downregulation on HIBD through the MALAT1/miR-140-5p/TGFBR1/NF-κB Signaling Pathway. Molecular neurobiology. 2024-09-15. PMID:39278884. |
knockdown of hif-1α was shown to mitigate brain tissue damage in a neonatal hibd rat model through the malat1/mir-140-5p/tgfbr1/nf-κb signaling axis, revealing a protective effect achieved by inhibiting hippocampal neuron apoptosis and potentially guiding the way toward therapeutic interventions in hibd. |
2024-09-15 |
2024-09-18 |
rat |
| Yan Huang, Shuang Li, Yuhan Yang, Kunyi Li, Lan Wen, Jinglun L. Chemerin 15 peptide reduces neuroinflammation via the ChemR23 receptor after ischemia-reperfusion injury. Neural regeneration research. 2024-09-09. PMID:39248165. |
we co-cultured bv2 microglial cells with ht-22 hippocampal neurons and observed that chemerin 15 reduced apoptosis in ht-22 cells. |
2024-09-09 |
2024-09-11 |
mouse |
| Zeina Hussein, Haidy E Michel, Reem N El-Naga, Ebtehal El-Demerdash, Eman M Mantaw. Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway. Neurotoxicology. vol 105. 2024-09-01. PMID:39209270. |
coenzyme q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: mechanistic roles of wnt/ β-catenin signaling pathway. |
2024-09-01 |
2024-09-04 |
rat |
| Grigory Demyashkin, Ekaterina Blinova, Migran Grigoryan, Mikhail Parshenkov, Polina Skovorodko, Vladimir Ius, Anastasia Lebed, Petr Shegay, Andrei Kapri. Neuroprotective Effects of Myricetin on PTZ-Induced Seizures in Mice: Evaluation of Oxidation, Neuroinflammation and Metabolism, and Apoptosis in the Hippocampus. Current issues in molecular biology. vol 46. issue 8. 2024-08-28. PMID:39194744. |
neuroprotective effects of myricetin on ptz-induced seizures in mice: evaluation of oxidation, neuroinflammation and metabolism, and apoptosis in the hippocampus. |
2024-08-28 |
2024-08-30 |
mouse |
| Chuan He, Tie Wang, Yanwu Han, Changyang Zuo, Guangming Wan. Jun-activated SOCS1 enhances ubiquitination and degradation of CCAAT/enhancer-binding protein β to ameliorate cerebral ischaemia/reperfusion injury. The Journal of physiology. 2024-08-28. PMID:39197117. |
it scrutinizes the role of the jun proto-oncogene in apoptosis, involvement of socs1 in neural precursor cell accumulation in ischaemic regions, and the upregulation of c-ebpβ in the hippocampus following i/r. |
2024-08-28 |
2024-08-31 |
mouse |
| Wanqing Zheng, Genghua Xu, Zhengwei Lue, Xinyu Zhou, Ning Wang, Yun Ma, Wenyue Yuan, Lushan Yu, Danyan Zhu, Xiangnan Zhan. Nervonic acid protects against oligodendrocytes injury following chronic cerebral hypoperfusion in mice. European journal of pharmacology. 2024-08-25. PMID:39182543. |
moreover, na mitigated demyelination and loss of oligodendrocytes in the corpus callosum and hippocampus of ruccao-treated mice, and prevented oligodendrocyte apoptosis. |
2024-08-25 |
2024-08-28 |
mouse |
| Yu Shi, Xiangyu Guo, Jie Zhang, Hanchi Zhou, Bei Sun, Jing Fen. Corrigendum to "DNA binding protein HMGB1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with OSA" [Brain Behav. Immun. 73 (2018) 482-492]. Brain, behavior, and immunity. 2024-08-24. PMID:39181822. |
corrigendum to "dna binding protein hmgb1 secreted by activated microglia promotes the apoptosis of hippocampal neurons in diabetes complicated with osa" [brain behav. |
2024-08-24 |
2024-08-28 |
Not clear |
| Xinxin Yang, Li Huang, Yanyan Zhang, Kaixin Wang, Shiya Liu, Xiaojin Li, Yuanyuan Ding, Daling Deng, Tianhao Zhang, Wenjing Zhao, Lulin Ma, Yafeng Wang, Shaofang Shu, Xiangdong Che. Untargeted metabolomics and mendelian randomization analysis identify alpha-linolenic acid and linoleic acid as novel biomarkers of perioperative neurocognitive dysfunction. Clinical nutrition (Edinburgh, Scotland). vol 43. issue 9. 2024-08-20. PMID:39163761. |
the results indicated that rats exposed to anesthesia and surgery exhibited poorer cognitive performance, significant elevations in hippocampal inflammatory factors such as il-1β and tnf-α, and extensive neuronal apoptosis. |
2024-08-20 |
2024-08-23 |
rat |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
pvt1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by mir-206-3p-dependent regulation of camk4. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
knockdown of pvt1 or camk4 abated se-induced proliferation inhibition, apoptosis, and inflammation in hippocampal neurons. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
similarly, overexpression of camk4 abolished mir-206-3p-evoked arrest of apoptosis and inflammation in hippocampal neurons under se condition. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
collectively, pvt1 contributed to se-induced apoptosis and inflammation in hippocampal neurons by modulating the mir-206-3p/camk4 axis, offering a novel insight into the prevention of epilepsy. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
moreover, downregulation of mir-206-3p reversed the inhibitory effects of pvt1 knockdown on se-induced apoptosis and inflammation in hippocampal neurons. |
2024-08-14 |
2024-08-16 |
mouse |