| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kusumoto, T Ogawa, K Mizumoto, H Ueno, H Niiyama, N Sato, M Nakamura, M Tanak. Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 8. 1999-10-27. PMID:10473098. |
thus, our results demonstrate that the p53 gene transduction directly inhibits telomerase activity, independent of its effects on cell growth arrest, cell cycle arrest, and apoptosis. |
1999-10-27 |
2023-08-12 |
human |
| M Cascalló, E Mercadé, G Capellà, F Lluís, C Fillat, A M Gómez-Foix, A Maz. Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells. Cancer gene therapy. vol 6. issue 5. 1999-10-26. PMID:10505853. |
taken together, our results indicate that the effects elicited by exogenous p53 protein depend upon the molecular alterations related to p53 actions on cell cycle and apoptosis. |
1999-10-26 |
2023-08-12 |
human |
| M L Linenberger, J L Rohn, T Deng, S Ellis-Smith, R Ingber, J Overbaug. Lymphokines modulate the growth and survival of thymic tumor cells containing a novel feline leukemia virus/Notch2 variant. Veterinary immunology and immunopathology. vol 70. issue 3-4. 1999-10-26. PMID:10507363. |
interleukin-4 abrogated hydrocortisone-induced apoptosis in all three populations and had divergent effects on cell line clonogenic colony formation. |
1999-10-26 |
2023-08-12 |
Not clear |
| C Tolis, G J Peters, C G Ferreira, H M Pinedo, G Giaccon. Cell cycle disturbances and apoptosis induced by topotecan and gemcitabine on human lung cancer cell lines. European journal of cancer (Oxford, England : 1990). vol 35. issue 5. 1999-10-07. PMID:10505042. |
topotecan (a topoisomerase i inhibitor) and gemcitabine (a deoxycytidine analogue), two active new drugs for the treatment of lung cancer, were evaluated for their growth inhibitory effect on human lung cancer cell lines and their effect on cell cycle perturbation, apoptosis and apoptosis-related genes. |
1999-10-07 |
2023-08-12 |
human |
| M Löffler, M J Ausserlechner, M Tonko, B L Hartmann, D Bernhard, S Geley, A Helmberg, R Kofle. c-Myc does not prevent glucocorticoid-induced apoptosis of human leukemic lymphoblasts. Oncogene. vol 18. issue 32. 1999-10-04. PMID:10467407. |
subsequent analyses of these cell lines showed that overexpression of c-myc per se had little, if any, effect on cell viability, although it rendered the cells more sensitive to apoptosis induced by low serum, confirming the functionality of the expressed transgene. |
1999-10-04 |
2023-08-12 |
human |
| C D Albright, C B Friedrich, E C Brown, M H Mar, S H Zeise. Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain research. Developmental brain research. vol 115. issue 2. 1999-09-13. PMID:10407130. |
in order to better understand the relationship between maternal diet, brain cytoarchitecture and behavior, we investigated the effects of choline availability on cell proliferation, apoptosis and differentiation in the fetal rat brain septum. |
1999-09-13 |
2023-08-12 |
rat |
| R W Nickell. Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death. Survey of ophthalmology. vol 43 Suppl 1. 1999-09-13. PMID:10416758. |
to date, the mechanism of ganglion cell apoptosis is poorly understood, but research on cell death in other areas has provided a blueprint for the study of dying ganglion cells in animal models. |
1999-09-13 |
2023-08-12 |
Not clear |
| O Lefebvre, D Wouters, C Méreau-Richard, T Facon, M Zandecki, P Formstecher, M T Beli. Induction of apoptosis by all-trans retinoic acid in the human myeloma cell line RPMI 8226 and negative regulation of some of its typical morphological features by dexamethasone. Cell death and differentiation. vol 6. issue 5. 1999-09-09. PMID:10381637. |
dex, when used alone, had no effect on cell growth and apoptosis. |
1999-09-09 |
2023-08-12 |
human |
| M De Saint Jean, F Brignole, G Feldmann, A Goguel, C Baudoui. Interferon-gamma induces apoptosis and expression of inflammation-related proteins in Chang conjunctival cells. Investigative ophthalmology & visual science. vol 40. issue 10. 1999-09-09. PMID:10476784. |
the purpose of this study was to investigate the effect of interferon (ifn)gamma on cell viability, cell growth, and apoptosis and on expression of apoptotic and inflammation-related proteins in epithelial conjunctival cells in vitro. |
1999-09-09 |
2023-08-12 |
Not clear |
| G Calviello, P Palozza, N Maggiano, P Franceschelli, F Di Nicuolo, M E Marcocci, G M Bartol. Effects of eicosapentaenoic and docosahexaenoic acids dietary supplementation on cell proliferation and apoptosis in rat colonic mucosa. Lipids. vol 34 Suppl. 1999-09-08. PMID:10419112. |
effects of eicosapentaenoic and docosahexaenoic acids dietary supplementation on cell proliferation and apoptosis in rat colonic mucosa. |
1999-09-08 |
2023-08-12 |
rat |
| P R Faraco, E C Ledgerwood, P Vandenabeele, J B Prins, J R Bradle. Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage. Biochemical and biophysical research communications. vol 261. issue 2. 1999-09-08. PMID:10425195. |
tumor necrosis factor induces distinct patterns of caspase activation in wehi-164 cells associated with apoptosis or necrosis depending on cell cycle stage. |
1999-09-08 |
2023-08-12 |
Not clear |
| S Vieira de Oliveira, J L Viana de Camargo, P R Cardoso, C R Padovani, S Fukushim. Effects of uracil calculi on cell growth and apoptosis in the BBN-initiated Wistar rat urinary bladder mucosa. Teratogenesis, carcinogenesis, and mutagenesis. vol 19. issue 4. 1999-08-30. PMID:10406893. |
effects of uracil calculi on cell growth and apoptosis in the bbn-initiated wistar rat urinary bladder mucosa. |
1999-08-30 |
2023-08-12 |
rat |
| H M Jin, Y D Di, Q J X. Effects of commercial glucose-based peritoneal dialysates on peripheral blood phagocytes apoptosis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. vol 19 Suppl 2. 1999-08-24. PMID:10406552. |
but few reports exist on cell apoptosis. |
1999-08-24 |
2023-08-12 |
Not clear |
| M Greave. Molecular genetics, natural history and the demise of childhood leukaemia. European journal of cancer (Oxford, England : 1990). vol 35. issue 2. 1999-08-23. PMID:10448256. |
most childhood leukaemias and some other mesenchymal stem cell tumours are of fetal origin and can metastasize without corruption of restraints on cell proliferation or bypassing apoptosis. |
1999-08-23 |
2023-08-12 |
Not clear |
| C E Schrader, W Edelmann, R Kucherlapati, J Stavneze. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. The Journal of experimental medicine. vol 190. issue 3. 1999-08-19. PMID:10430621. |
mmr deficiency had no effect on cell proliferation, viability, or apoptosis, as detected by [(3)h]thymidine incorporation and by propidium iodide staining. |
1999-08-19 |
2023-08-12 |
mouse |
| N Buisson-Legendre, P Bernard, H Bobichon, H Emonard, C Schneider, F X Maquart, B Haye, W Hornebec. Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth. Biochemical and biophysical research communications. vol 260. issue 3. 1999-08-16. PMID:10403818. |
triggering the ceramide pathway by exogenous treatment with neutral sphingomyelinase (smase) inhibited human keratinocyte growth rate, while having no influence on cell apoptosis. |
1999-08-16 |
2023-08-12 |
human |
| L Ji, B Fang, N Yen, K Fong, J D Minna, J A Rot. Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression. Cancer research. vol 59. issue 14. 1999-08-12. PMID:10416589. |
we studied the effects of fragile histidine triad (fhit) gene overexpression mediated by an adenoviral vector, ad-fhit, on cell proliferation, apoptosis, and cell cycle kinetics in human cancer cells and on tumorigenicity and tumor growth in nude mice. |
1999-08-12 |
2023-08-12 |
mouse |
| S M Janicki, M J Monteir. Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant. The American journal of pathology. vol 155. issue 1. 1999-07-26. PMID:10393846. |
to investigate the mechanism by which presenilin (ps) overexpression induces apoptosis, we studied the effects of these proteins on cell cycle progression. |
1999-07-26 |
2023-08-12 |
Not clear |
| L Gollapudi, M M Oblinge. Estrogen and NGF synergistically protect terminally differentiated, ERalpha-transfected PC12 cells from apoptosis. Journal of neuroscience research. vol 56. issue 5. 1999-07-23. PMID:10369214. |
we challenged differentiated pcer and pccon cells with serum-free media and assessed the effects of various treatments on cell survival and apoptosis using trypan blue staining and quantitative tunel staining. |
1999-07-23 |
2023-08-12 |
rat |
| M Buemi, A Allegra, M Senatore, D Marino, M A Medici, C Aloisi, G Di Pasquale, F Coric. Pro-apoptotic effect of fluvastatin on human smooth muscle cells. European journal of pharmacology. vol 370. issue 2. 1999-07-16. PMID:10323270. |
we therefore evaluated the effect, in vitro, of the addition of the serum of patients taking fluvastatin on human smooth muscle cells in order to ascertain the effect of the drug on cell proliferation and apoptosis. |
1999-07-16 |
2023-08-12 |
human |