| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Balabhadrapathruni, T J Thomas, E J Yurkow, P S Amenta, T Thoma. Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells. Oncology reports. vol 7. issue 1. 2000-01-11. PMID:10601582. |
effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in mda-mb-468 human breast cancer cells. |
2000-01-11 |
2023-08-12 |
human |
| M S Jan, L Y Wing, M T Lin, Y S Li. alpha-Difluoromethylornithine blocks thymocyte apoptosis via a reduction in tyrosine phosphorylation. Scandinavian journal of immunology. vol 50. issue 6. 2000-01-11. PMID:10607308. |
the effect of alpha-difluoromethylornithine on cell apoptosis was investigated. |
2000-01-11 |
2023-08-12 |
mouse |
| R De Vincenzo, C Ferlini, M Distefano, C Gaggini, A Riva, E Bombardelli, P Morazzoni, B Danieli, G Capelli, S Mancuso, G Scambi. Biological evaluation on different human cancer cell lines of novel colchicine analogs. Oncology research. vol 11. issue 3. 1999-12-23. PMID:10527074. |
to gain further insight into the mechanism of the antitumor activity of colchicinoids, the most active compounds, colchicone and thiocolchicone, were selected to evaluate their effect on cell cycle, apoptosis, and tubulin interaction. |
1999-12-23 |
2023-08-12 |
human |
| F J Authier, B Chazaud, A Plonquet, M C Eliezer-Vanerot, F Poron, L Belec, G Barlovatz-Meimon, R K Gherard. Differential expression of the IL-1 system components during in vitro myogenesis: implication of IL-1beta in induction of myogenic cell apoptosis. Cell death and differentiation. vol 6. issue 10. 1999-12-23. PMID:10556979. |
exposure of cultures to exogenous il-1beta (1-5 ng/ml) induced myogenic cell apoptosis, without effect on cell proliferation or fusion. |
1999-12-23 |
2023-08-12 |
human |
| J A Costoya, J Finidori, S Moutoussamy, R Seãris, J Devesa, V M Arc. Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway. Endocrinology. vol 140. issue 12. 1999-12-20. PMID:10579361. |
we also showed that the inhibitory action of gh on apoptosis is probably mediated via stimulation of the serine-threonine kinase akt, as 1) gh treatment induces a prompt phosphorylation of akt; and 2) gh effects on cell survival are abolished by transfection of an akt mutant that exhibits dominant negative function. |
1999-12-20 |
2023-08-12 |
human |
| M M Behrens, U Strasser, J Y Koh, B J Gwag, D W Cho. Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase. Neuroscience. vol 94. issue 3. 1999-12-17. PMID:10579584. |
consistent with previous studies on cell lines and non-neuronal cells, specific inhibitors of protein kinase c induced mouse primary cultured neocortical neurons to undergo apoptosis. |
1999-12-17 |
2023-08-12 |
mouse |
| B Gururajanna, A A Al-Katib, Y W Li, O Aranha, V K Vaitkevicius, F H Sarka. Molecular effects of taxol and caffeine on pancreatic cancer cells. International journal of molecular medicine. vol 4. issue 5. 1999-12-15. PMID:10534572. |
human pancreatic adenocarcinoma cell lines, hpac and panc-1 containing wild-type and mutant p53 respectively, were used to investigate the effects of taxol and caffeine on cell growth, and their effects on the modulation of cell cycle and apoptosis related genes. |
1999-12-15 |
2023-08-12 |
human |
| R V Sionov, Y Haup. The cellular response to p53: the decision between life and death. Oncogene. vol 18. issue 45. 1999-12-15. PMID:10557106. |
whether the cell enters growth arrest or undergoes apoptosis, depends on the final integration of incoming signals with antagonistic effects on cell growth. |
1999-12-15 |
2023-08-12 |
Not clear |
| A I Scovassi, G G Poirie. Poly(ADP-ribosylation) and apoptosis. Molecular and cellular biochemistry. vol 199. issue 1-2. 1999-11-30. PMID:10544961. |
the aim of this review is to discuss the possible involvement of poly(adp-ribosylation) during apoptosis, by dealing with general considerations on apoptosis, and further examining the correlation between nad consumption and cell death, the regulation of poly(adp-ribose) metabolism in apoptotic cells, the effect of poly(adp-ribose) polymerase inhibition on cell death occurrence and the use of enzyme cleavage as a marker of apoptosis. |
1999-11-30 |
2023-08-12 |
Not clear |
| M N Zoubine, A P Weston, D C Johnson, D R Campbell, S K Banerje. 2-methoxyestradiol-induced growth suppression and lethality in estrogen-responsive MCF-7 cells may be mediated by down regulation of p34cdc2 and cyclin B1 expression. International journal of oncology. vol 15. issue 4. 1999-11-24. PMID:10493943. |
the estradiol metabolite 2-methoxyestradiol (2-me) when present in the culture medium in concentrations greater than 1 microm for three days, dose-dependently reduced the effectiveness of e2 on cell proliferation by increasing the rate of apoptosis. |
1999-11-24 |
2023-08-12 |
Not clear |
| A Olivera, T Kohama, L Edsall, V Nava, O Cuvillier, S Poulton, S Spiege. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. The Journal of cell biology. vol 147. issue 3. 1999-11-24. PMID:10545499. |
n,n-dimethylsphingosine, a competitive inhibitor of sphingosine kinase, blocked the effects of sphingosine kinase overexpression on cell proliferation and suppression of apoptosis. |
1999-11-24 |
2023-08-12 |
Not clear |
| J Lee, B J Park, J H Park, M H Yang, S G Ch. TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells. Experimental & molecular medicine. vol 31. issue 3. 1999-11-23. PMID:10551260. |
to characterize the tgf-beta1 response of monocytic leukemia cells, we analyzed the effects of tgf-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic u937 cells. |
1999-11-23 |
2023-08-12 |
human |
| J Liu, J Kolath, J Anderson, C Kolar, T A Lawson, J Talmadge, W H Gmeine. Positive interaction between 5-FU and FdUMP[10] in the inhibition of human colorectal tumor cell proliferation. Antisense & nucleic acid drug development. vol 9. issue 5. 1999-11-23. PMID:10555156. |
effects on cell viability were measured using an assay for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), while cytotoxicity and apoptosis were investigated using clonogenic and tunel assays, respectively. |
1999-11-23 |
2023-08-12 |
human |
| H B Jenson, J Baillargeon, P Heard, M P Moye. Effects of smokeless tobacco and tumor promoters on cell population growth and apoptosis of B lymphocytes infected with epstein-barr virus types 1 and 2. Toxicology and applied pharmacology. vol 160. issue 2. 1999-11-04. PMID:10527916. |
effects of smokeless tobacco and tumor promoters on cell population growth and apoptosis of b lymphocytes infected with epstein-barr virus types 1 and 2. |
1999-11-04 |
2023-08-12 |
Not clear |
| H B Jenson, J Baillargeon, P Heard, M P Moye. Effects of smokeless tobacco and tumor promoters on cell population growth and apoptosis of B lymphocytes infected with epstein-barr virus types 1 and 2. Toxicology and applied pharmacology. vol 160. issue 2. 1999-11-04. PMID:10527916. |
the effects of smokeless tobacco purified products 4-(n-methyl-n-nitrosamine)-1-3-pyridinyl)-1-butanone (nnk) and n-nitrosonornicotine (nnn), smokeless tobacco extracts (dry snuff, moist snuff, and loose leaf), and the tumor promoters 12-o-tetradecanoyl phorbol-13-acetate (tpa) and n-butyrate on cell population growth, cell death, and apoptosis were studied in b lymphocyte cell lines harboring epstein-barr virus (ebv) type 1 (raji and x50-7) or type 2 (hr-1k and ag876) and in an ebv-uninfected control lymphocyte cell line (ramos). |
1999-11-04 |
2023-08-12 |
Not clear |
| H B Jenson, J Baillargeon, P Heard, M P Moye. Effects of smokeless tobacco and tumor promoters on cell population growth and apoptosis of B lymphocytes infected with epstein-barr virus types 1 and 2. Toxicology and applied pharmacology. vol 160. issue 2. 1999-11-04. PMID:10527916. |
the greatest effects on cell population growth, cell death, and apoptosis on cells harboring lytic ebv type 1 (x50-7) was with each of the three smokeless tobacco extracts. |
1999-11-04 |
2023-08-12 |
Not clear |
| S Naderi, R Blomhoff, J Myklebust, E B Smeland, B Erikstein, K R Norum, H K Blomhof. Lovastatin inhibits G1/S transition of normal human B-lymphocytes independent of apoptosis. Experimental cell research. vol 252. issue 1. 1999-11-01. PMID:10502407. |
in the present study we have elucidated the effects of lovastatin on cell cycle progression and apoptosis of normal human b-lymphocytes. |
1999-11-01 |
2023-08-12 |
human |
| S Naderi, R Blomhoff, J Myklebust, E B Smeland, B Erikstein, K R Norum, H K Blomhof. Lovastatin inhibits G1/S transition of normal human B-lymphocytes independent of apoptosis. Experimental cell research. vol 252. issue 1. 1999-11-01. PMID:10502407. |
thus, it appears that accelerated apoptosis cannot account for the effect of lovastatin on cell cycle progression. |
1999-11-01 |
2023-08-12 |
human |
| H Akiyama, K Suzuki, T Ino, I Katsuda, M Hiran. [Evaluation of cytarabine-induced apoptosis in leukemic cell lines; utility of annexin V method]. Rinsho byori. The Japanese journal of clinical pathology. vol 47. issue 8. 1999-10-29. PMID:10511810. |
the advantage of annexin v method which detects phosphatidylserine emerging on cell surface during the early course of apoptosis included simplicity and rapidity of the procedure and short time requirement for apoptosis to appear after incubation with cytarabine. |
1999-10-29 |
2023-08-12 |
Not clear |
| M Kusumoto, T Ogawa, K Mizumoto, H Ueno, H Niiyama, N Sato, M Nakamura, M Tanak. Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 8. 1999-10-27. PMID:10473098. |
adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. |
1999-10-27 |
2023-08-12 |
human |