| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao Liu, Qing Gao, Jian Dong, Hui Ca. Usf2 Deficiency Promotes Autophagy to Alleviate Cerebral Ischemia-Reperfusion Injury Through Suppressing YTHDF1-m6A-Mediated Cdc25A Translation. Molecular neurobiology. 2023-11-02. PMID:37914905. |
our results showed that usf2 was significantly upregulated in ogd/r-treated ht22 neurons that displayed an increased level in cell apoptosis and decreased levels in cell viability and autophagy, and interference of usf2 largely rescued the effects of ogd/r on cell viability, apoptosis, and autophagy, suggesting an important role of usf2 in neuron autophagy. |
2023-11-02 |
2023-11-08 |
mouse |
| Xuelan Gan, Fan Wang, Jianguo Luo, Yunfei Zhao, Yan Wang, Chao Yu, Jun Che. Proteolysis Targeting Chimeras (PROTACs) Based on Celastrol Induce Multiple Protein Degradation for Triple-Negative Breast Cancer Treatment. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2023-10-28. PMID:37898394. |
furthermore, compound 6a has demonstrated remarkable inhibitory effects on cell proliferation and migration, and induction of apoptosis in 4t1 cells through cell cycle arrest and activation of the bcl-2/bax/cleaved caspase-3 apoptotic pathway. |
2023-10-28 |
2023-11-08 |
Not clear |
| Hairui Fan, Dongjie Zhou, Xiaomei Zhang, Min Jiang, Xiang Kong, Tongmin Xue, Lingling Gao, Dan Lu, Chenyue Tao, Liping Wan. Hsa_circRNA_BECN1 acts as a ceRNA to promote polycystic ovary syndrome progression by sponging the miR-619-5p/Rab5b axis. Molecular human reproduction. 2023-10-26. PMID:37882757. |
additionally, rescue experiments demonstrated that overexpressing rab5b reversed the effects of circ_becn1 knockdown on cell proliferation and apoptosis in kgn cells. |
2023-10-26 |
2023-11-08 |
human |
| Thanayod Sasivimolrattana, Arkom Chaiwongkot, Parvapan Bhattarakoso. HPV16E1 downregulation altered the cell characteristics involved in cervical cancer development. Scientific reports. vol 13. issue 1. 2023-10-25. PMID:37880374. |
however, no effect on cell migration and apoptosis properties was found. |
2023-10-25 |
2023-11-08 |
human |
| Hongcan Zhao, Guoqian Xiang, Tingjun Shao, Minmin Wang, Weijian Da. HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway. Open life sciences. vol 18. issue 1. 2023-10-20. PMID:37854321. |
cell counting kit-8, clone formation, transwell, and flow cytometry assays were used in evaluating the effects of hk2 and erk1/2 on cell proliferation, migration, and apoptosis. |
2023-10-20 |
2023-11-08 |
Not clear |
| Edmund C R Watson, Warren Baker, David Ahern, Danson Loi, Adam P Cribbs, Udo Opperman. Mass cytometry as a tool in target validation and drug discovery. Methods in enzymology. vol 690. 2023-10-20. PMID:37858540. |
the second experiment explores the impact of a kinase inhibitor on cell cycle and apoptosis pathways of a human myeloma cell line. |
2023-10-20 |
2023-11-08 |
human |
| Hezhao Zhang, Zhiyong Shi, Yarong Guo, Dongdong Wu, Gao Yu, Jun X. Tumor Necrosis Factor Alpha-Induced Protein-3 Inhibits the Activation of Hepatic Stellate Cells by Regulating the p65 Molecule in the NF-κB Signaling Pathway. Alternative therapies in health and medicine. 2023-10-19. PMID:37856812. |
cell counting kit-8 (cck8), colony growth, transwell assays, cell cycle analysis, and apoptosis assays were performed to explore the effect of a20 on cell function in vitro. |
2023-10-19 |
2023-11-08 |
mouse |
| Fabio Francavilla, Federica Sarcina, Igor A Schepetkin, Lilya N Kirpotina, Marialessandra Contino, Annalisa Schirizzi, Giampiero De Leonardis, Andrei I Khlebnikov, Rosalba D'Alessandro, Mark T Quinn, Enza Lacivita, Marcello Leopold. Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models. European journal of medicinal chemistry. vol 261. 2023-10-15. PMID:37839346. |
both compounds potently inhibited cell growth through a combined effect on cell proliferation and apoptosis and reduced cell migration, while inducing an increase in angiogenesis, thus suggesting that fpr1 could play a dual role as oncogene and onco-suppressor. |
2023-10-15 |
2023-11-08 |
Not clear |
| Rawan Salih, Khalid Bajou, Baraah Shaker, Abdelaziz Elgamou. Antitumor effect of algae silver nanoparticles on human triple negative breast cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 168. 2023-10-13. PMID:37832405. |
the observed effects are not attributed to the agnps, as demonstrated by the lack of impact of the starch-agnps (used as a negative control) on cell survival and apoptosis. |
2023-10-13 |
2023-10-15 |
mouse |
| Cundi Zhong, Qiang Zhang, Haiping Bao, Yu Li, Chen Ni. Hsa_circ_0054220 Upregulates HMGA1 by the Competitive RNA Pattern to Promote Neural Impairment in MPTP Model of Parkinson's Disease. Applied biochemistry and biotechnology. 2023-10-10. PMID:37815624. |
hmga1 overexpression counteracted the function of circ_0054220 silencing on cell apoptosis. |
2023-10-10 |
2023-10-15 |
mouse |
| Chengcun Zhu, Zhou Sun, Jie Wang, Xiangdi Meng, Zhaosen Ma, Rui Guo, Jiqiang Niu, Lisa Jia Tran, Jing Zhang, Tianxiao Jiang, Yunfei Liu, Fangdie Ye, Baoluo M. Exploring oncogenes for renal clear cell carcinoma based on G protein-coupled receptor-associated genes. Discover. Oncology. vol 14. issue 1. 2023-10-10. PMID:37816979. |
g protein-coupled receptors (gpcrs) are a class of receptors on cell membranes that regulate various biological processes in cells, such as cell proliferation, differentiation, migration, apoptosis, and metabolism, by interacting with g proteins. |
2023-10-10 |
2023-10-15 |
Not clear |
| Qianwen Zhang, Yiyu He, Hao Xu, Yuqiao Zeng, Li Wang, Zengxi Xue, Qingyun Sun, Likun Wan. MicroRNA-181a-5p alleviates acute liver failure in mice by inhibiting HMGB1. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807324. |
microrna-181a-5p could directly target hmgb1 mrna and repress its expressions, in further hmgb1 is involved in microrna-181a-5p effect on cell apoptosis of alf. |
2023-10-09 |
2023-10-15 |
mouse |
| Yujia Sun, Tianqi Zhao, Yaoyao Ma, Xinyi Wu, Shuangfeng Chu, Zhangping Yan. Multiple roles of LncRNA-BMNCR on cell proliferation and apoptosis by targeting miR-145/CBFB axis in BMECs. The veterinary quarterly. 2023-10-09. PMID:37807922. |
multiple roles of lncrna-bmncr on cell proliferation and apoptosis by targeting mir-145/cbfb axis in bmecs. |
2023-10-09 |
2023-10-15 |
cattle |
| Zhaobin Pan, Zhiming Tan, Hongyan Li, Yang Wang, Haiyan Du, Jinhui Sun, Chunchao Li, Shicai Ye, Xin Li, Juanhua Qua. Diosmetin induces apoptosis and protective autophagy in human gastric cancer HGC-27 cells via the PI3K/Akt/FoxO1 and MAPK/JNK pathways. Medical oncology (Northwood, London, England). vol 40. issue 11. 2023-10-05. PMID:37796396. |
in this study, we aimed to investigate the impact of diosmetin on cell proliferation, migration, cell cycle progression and apoptosis in human gastric cancer hgc-27 cells. |
2023-10-05 |
2023-10-07 |
human |
| Di Liu, Yize Guo, Qin Du, Yuxuan Zhu, Ya Gu. RING induces cell cycle arrest and apoptosis in human breast cancer cells by regulating the HSF1/MT2A axis. Experimental cell research. 2023-10-05. PMID:37797799. |
moreover, ectopic expression of mt2a reversed the inhibitory effect of ring1 on cell proliferation and clonogenesis, and antagonized the promotion effect of ring1 on cell cycle arrest and apoptosis in bc cells. |
2023-10-05 |
2023-10-07 |
mouse |
| Ali Tafti, Samaneh Shojaei, Hakimeh Zali, Saeed Karima, Samira Mohammadi-Yeganeh, Mahdieh Mondanizade. A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle-related genes and miRNAs in triple-negative breast cancer cells. Molecular carcinogenesis. 2023-10-03. PMID:37787375. |
we performed flow cytometry to investigate rapamycin's impact on cell cycle and apoptosis. |
2023-10-03 |
2023-10-07 |
Not clear |
| Huan Deng, Xuedong Shu, Yao Wang, Junwei Zhang, Yue Yin, Fang Wu, Jing H. Matrix Stiffness Regulated Endoplasmic Reticulum Stress-mediated Apoptosis of Osteosarcoma Cell through Ras Signal Cascades. Cell biochemistry and biophysics. 2023-10-03. PMID:37789235. |
while the cell spreading increased and the apoptosis decreased with the matrix stiffness, such modulating effect of matrix on cell spreading exhibited different time evolvement behaviors as a function of stiffness, which likely led to surprisingly similar apoptosis rates for the 30 kpa and 250 kpa samples. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ayşe Çakır Gündoğdu, Neziha Senem Arı, Asiye Höbel, Gülnihal Şenol, Ömer Eldiven, Fatih Ka. Boric Acid Exhibits Anticancer Properties in Human Endometrial Cancer Ishikawa Cells. Cureus. vol 15. issue 8. 2023-09-29. PMID:37772231. |
objective this study aims to explore the potential anti-cancer properties of boric acid (ba) in human endometrial cancer ishikawa cells by assessing its influence on cell viability, apoptosis, oxidative stress, and inflammatory responses. |
2023-09-29 |
2023-10-07 |
human |
| Alexus Acton, William J Placze. Myeloid Cell Leukemia 1 Small Molecule Inhibitor S63845 Synergizes with Cisplatin in Triple-Negative Breast Cancer. Cancers. vol 15. issue 18. 2023-09-28. PMID:37760451. |
the use of combined mcl1 inhibitors with cisplatin in tnbc effectively initiates tap73 anti-tumor effects on cell cycle arrest and apoptosis. |
2023-09-28 |
2023-10-07 |
Not clear |
| Shohreh Jafarinejad, William H C Martin, Bayan Abu Ras, Mohammad Isreb, Badie Jacob, Abid Aziz, Zahra Adoul, Ruby Lagnado, Richard D Bowen, Mojgan Najafzade. The anticancer/cytotoxic effect of a novel gallic acid derivative in non-small cell lung carcinoma A549 cells and peripheral blood mononuclear cells from healthy individuals and lung cancer patients. BioFactors (Oxford, England). 2023-09-28. PMID:37768028. |
the cell counting kit-8 (cck-8) assay was used to detect the effect of ga, mbs, dmbs, and tmbs on cell proliferation and apoptosis in peripheral blood mononuclear cells (pbmcs) from healthy individuals and non-small cell lung carcinoma a549 cells. |
2023-09-28 |
2023-10-07 |
Not clear |