| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyi Meng, Min Li, Ming Qiao, Xue Li, Jianhua Yang, Junping H. Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2023-12-14. PMID:38094222. |
this study explored the effects of hugan buzure (hbr) on cell apoptosis and autophagy in hepatocellular carcinoma (hcc) and the molecular mechanisms of the pi3k/akt/mtor signaling pathway. |
2023-12-14 |
2023-12-17 |
Not clear |
| Esmat Abdi, Saeid Latifi-Navid, Alireza Panah. Long noncoding RNA polymorphisms in gynecological cancers. Personalized medicine. 2023-12-14. PMID:38095072. |
regarding the effect of long noncoding rnas (lncrnas) on cell differentiation, proliferation and apoptosis, variations in their expression cause different anomalies, such as tumorigenesis. |
2023-12-14 |
2023-12-17 |
Not clear |
| Huaguo Xiang, Hongping Tang, Qingqing He, Junfang Sun, Yihui Yang, Lingyue Kong, Yingzhen Wan. NDUFA8 is transcriptionally regulated by EP300/H3K27ac and promotes mitochondrial respiration to support proliferation and inhibit apoptosis in cervical cancer. Biochemical and biophysical research communications. vol 693. 2023-12-14. PMID:38096616. |
ndufa8 knockdown or overexpression experiments were conducted to evaluate its impact on cell proliferation and apoptosis. |
2023-12-14 |
2023-12-17 |
Not clear |
| Rong Luo, Lan Li, Qingluan Han, Jingsong Fu, Fan Xia. HAGLR, stabilized by m6A modification, triggers PTEN-Akt signaling cascade-mediated RPE cell pyroptosis via sponging miR-106b-5p. Journal of biochemical and molecular toxicology. 2023-12-13. PMID:38088496. |
aberrantly overexpressed haglr was uncovered in the serum samples of dr patients and hg-induced hrpe cells, of which knockdown attenuated hg-induced cytotoxic impacts on cell apoptosis and pyroptosis. |
2023-12-13 |
2023-12-17 |
human |
| X-J Li, J Li, Q-Q Zhang, L-P Su, Y Guo, X-L Gong, J-J Yao, L Wang, Z-Q Zhan. The expression of annexin-A1 in esophageal squamous cell carcinoma and its association with the biological behavior of the primary human esophageal squamous carcinoma cell line. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 74. issue 5. 2023-12-12. PMID:38085519. |
a methyl-thiazolyl-tetrazolium assay was used to observe the effect of annexin-a1 on cell proliferation, and flow cytometry was conducted to analyze its effect on cell cycles and apoptosis. |
2023-12-12 |
2023-12-17 |
human |
| Sheng Li, Xiaoliang Cai, Liang Chen, Manbian Lin, Ziqi Zhu, Huihuang Xiao, Pingping Nie, Quanwen Chen, Xiaoyu Yan. Inhibition of hepatocellular carcinoma growth PeerJ. vol 11. 2023-12-12. PMID:38084140. |
cur-bbr treatment upregulated sox11 expression, and overexpression of sox11 restored the inhibitory effects of cur-bbr on cell growth, migration, and invasion and promoted apoptosis in the presence of mir-221. |
2023-12-12 |
2023-12-17 |
Not clear |
| Jian Shou, Chuanling Zhang, Xiaoyu Zheng, Yaowei Li, Peng Wu, Long Chen, XiuJun We. LncRNA HCP5 Facilitates the Progression of Ovarian Cancer by Interacting with the PTBP1 Protein. Biochemical genetics. 2023-12-10. PMID:38071681. |
furthermore, in hcp5-overexpressing oc cells, the impacts of hcp5 on cell proliferation and apoptosis were significantly attenuated by the knockdown of ptbp1. |
2023-12-10 |
2023-12-17 |
Not clear |
| Pengyu Geng, Jinhui Zhao, Qi Li, Xiaolin Wang, Wangshu Qin, Ting Wang, Xianzhe Shi, Xinyu Liu, Jia Chen, Hongdeng Qiu, Guowang X. Z-Ligustilide Combined with Cisplatin Reduces PLPP1-Mediated Phospholipid Synthesis to Impair Cisplatin Resistance in Lung Cancer. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069368. |
a further study showed that plpp1 expression was positively correlated with good prognosis, whereas the knockdown of plpp1 abolished the effects of z-ligustilide+cisplatin on cell cycle and apoptosis. |
2023-12-09 |
2023-12-17 |
Not clear |
| Weixing Xu, Hua Li. Is CaMKII friend or foe for cell apoptosis in eye?: A narrative review. Medicine. vol 102. issue 48. 2023-12-05. PMID:38050317. |
however, it seems that previous studies have generated conflicting conclusions about the effect of camkii on cell apoptosis. |
2023-12-05 |
2023-12-10 |
Not clear |
| Zhiyuan Li, Jingwei Li, Xiaofei Liu, Yang Liu, Hanhan Chen, Xiaohui Su. β-eudesmol inhibits cell proliferation and induces ferroptosis via regulating MAPK signaling pathway in breast cancer. Toxicon : official journal of the International Society on Toxinology. vol 237. 2023-12-01. PMID:38030095. |
cell counting kit-8, colony formation assay, and flow cytometry were performed to evaluate the influences of β-eudesmol on cell viability, proliferation, and apoptosis. |
2023-12-01 |
2023-12-10 |
Not clear |
| Hualong He, Wan Yang, Yaojie Shi, Xin Chen, Xinyi Chen, Xiang Hu, Xinyue Li, Yingyue Yang, Zhihao Liu, Tinghong Ye, Ningyu Wang, Luoting Y. Design and synthesis of the first PARP-1 and proteasome dual inhibitors to treat breast cancer. European journal of medicinal chemistry. vol 264. 2023-12-01. PMID:38039793. |
additionally, 42i induced more significant apoptosis and showed better inhibitory effect on cell proliferation in clonal formation experiments in breast cancer cells than 42d. |
2023-12-01 |
2023-12-10 |
Not clear |
| Yindi Bao, Lianzhi Wu, Yi Liu, Cuifang Fan, Jun Zhang, Jing Yan. Role of CircCHD2 in the pathogenesis of gestational diabetes mellitus by regulating autophagy via miR-33b-3p/ULK1 axis. Placenta. vol 145. 2023-12-01. PMID:38039841. |
further studies showed that the inhibition of mir-33b-3p significantly blocked the effects of circchd2 downregulation on cell viability, apoptosis, and autophagy in hg-treated htr-8/svneo cells. |
2023-12-01 |
2023-12-10 |
human |
| Yindi Bao, Lianzhi Wu, Yi Liu, Cuifang Fan, Jun Zhang, Jing Yan. Role of CircCHD2 in the pathogenesis of gestational diabetes mellitus by regulating autophagy via miR-33b-3p/ULK1 axis. Placenta. vol 145. 2023-12-01. PMID:38039841. |
ulk1 overexpression notably blocked the effects of mir-33b-3p mimics on cell viability, apoptosis, and autophagy in hg-treated htr-8/svneo cells. |
2023-12-01 |
2023-12-10 |
human |
| Sen Zhou, Yang Liu, Binbin Xue, Peigen Yua. Low-dose Esketamine suppresses NLRP3-mediated apoptotic and pyroptotic cell death in microglial cells to ameliorate LPS-induced depression via ablating GSK-3β. Behavioural brain research. vol 459. 2023-11-30. PMID:38029844. |
next, by conducting mechanical experiments, we verified that low-dose esketamine downregulated gsk-3β to inactivate nlrp3 inflammasome, and the effects of low-dose esketamine on cell pyroptosis, neuroinflammation and apoptosis in the lps-treated microglial cells were all abrogated by overexpressing gsk-3β and nlrp3. |
2023-11-30 |
2023-12-10 |
mouse |
| Han Wang, Yonghao Xiao, Yuanguo Zhang, Zhu Meng, Chenyu Zhao, Fanshan Qiu, Chongchong Li, Zengguo Fen. Study on the effect of type III recombinant humanized collagen on human vascular endothelial cells. Tissue engineering. Part C, Methods. 2023-11-29. PMID:38019085. |
the effect of hcolii on proliferation of ea.hy926 cells was detected by mtt assay, the effect of hcolii on cell migration was investigated by scratch assay, the effect of hcoliii on cell cycle and apoptosis was detected by flow cytometry, the ability of hcolii to induce angiogenesis of ea.hy926 cells was evaluated by angiogenesis assay, and the effect of hcolii on vegf expression was detected by rt-pcr analysis. |
2023-11-29 |
2023-12-07 |
human |
| Kaitriana E Colling, Emily L Symons, Lorenzo Buroni, Hiruni K Sumanisiri, Jessica Andrew-Udoh, Emily Witt, Haley A Losh, Abigail M Morrison, Kimberly K Leslie, Christopher J Dunnill, Johann S De Bono, Kristina W Thie. Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014133. |
we provide proof-of-concept data demonstrating the effect of cytotoxic agents on cell health, apoptosis and viability. |
2023-11-28 |
2023-11-29 |
human |
| Jiajie Ren, Tieli Son. BRD4 inhibition improves the efficacy of cisplatin and radiotherapy in oral squamous cell carcinoma by suppressing PD-L1 expression. Basic & clinical pharmacology & toxicology. 2023-11-28. PMID:38014458. |
in this study, we found that the brd4 inhibitor jq1 effectively enhanced the inhibitory effects of cisplatin and radiotherapy on cell proliferation and promoted the apoptosis of oscc cells by cisplatin and radiotherapy. |
2023-11-28 |
2023-11-29 |
Not clear |
| Büşra Hilal, Aslı Eldem, Tuba Oz, Melek Pehlivan, Ibrahim Piri. Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells. Biological trace element research. 2023-11-28. PMID:38015327. |
we aimed to investigate the effect of ba on cell proliferation, apoptosis, and oxidative stress in the jurkat cells. |
2023-11-28 |
2023-11-29 |
Not clear |
| Büşra Hilal, Aslı Eldem, Tuba Oz, Melek Pehlivan, Ibrahim Piri. Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells. Biological trace element research. 2023-11-28. PMID:38015327. |
the effects of ba on cell viability were determined by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2h-tetrazolium-5-carboxanilide (xtt) assay for 24-48-72 h. the impact of ba on apoptosis was analyzed by acridine orange/ethidium bromide. |
2023-11-28 |
2023-11-29 |
Not clear |
| Chao Chen, Yuqiong Chen, Mingzhu Xu, Lin Chen, Zhongqi Sun, Junrong Gong, Yafei Li, Tingbo Jian. Cucurbitacin B protects against myocardial ischemia-reperfusion injury through activating JAK2/STAT3 signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 11. 2023-11-28. PMID:38015527. |
the main purpose of the present study was to investigate the effect of cucurbitacin b on cell apoptosis and oxidative damage after myocardial i/r injury in vitro and in vivo and elucidate the molecular mechanisms underlying its role. |
2023-11-28 |
2023-11-29 |
mouse |