Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Abhinav Diwan, Andrew G Koesters, Devan Capella, Hartmut Geiger, Theodosia A Kalfa, Gerald W Dor. Targeting erythroblast-specific apoptosis in experimental anemia. Apoptosis : an international journal on programmed cell death. vol 13. issue 8. 2008-09-17. PMID:18584327. |
erythrocyte production is regulated by balancing precursor cell apoptosis and survival signaling. |
2008-09-17 |
2023-08-12 |
mouse |
Qin-Hui Tuo, Heng Zeng, Amanda Stinnett, Heidi Yu, Judy L Aschner, Daun-Fang Liao, Jian-Xiong Che. Critical role of angiopoietins/Tie-2 in hyperglycemic exacerbation of myocardial infarction and impaired angiogenesis. American journal of physiology. Heart and circulatory physiology. vol 294. issue 6. 2008-08-15. PMID:18408125. |
using streptozotocin (stz) mice subjected to myocardial ischemia, we examined the effects of shifting the ang-2-to-ang-1 ratio on myocardial infarction size, apoptosis, bone marrow (bm) cell-endothelial progenitor cell (epc) differentiation, and angiogenesis. |
2008-08-15 |
2023-08-12 |
mouse |
Abdulla K Salahudeen, Naeem Haider, John Jenkins, Manish Joshi, Harnish Patel, Hong Huang, Ming Yang, He Zh. Antiapoptotic properties of erythropoiesis-stimulating proteins in models of cisplatin-induced acute kidney injury. American journal of physiology. Renal physiology. vol 294. issue 6. 2008-07-31. PMID:18385271. |
erythropoietin (epo) induces erythrocytosis by suppressing erythroid progenitor cell apoptosis through the janus-activated kinase-signal transducers and activators of transcription (jak-stat) pathway. |
2008-07-31 |
2023-08-12 |
human |
Hongwei Shao, Yaohong Tan, Darwin Eton, Zhe Yang, M Georgina Uberti, Sen Li, Andrew Schulick, Hong Y. Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels. Stem cells (Dayton, Ohio). vol 26. issue 5. 2008-07-28. PMID:18308946. |
more cell proliferation, less apoptosis, enhanced bone marrow-derived endothelial progenitor cell (epc) incorporation and higher capillary density were observed in ischemic tissue treated with both statin and sdf-1. |
2008-07-28 |
2023-08-12 |
mouse |
Hongwei Shao, Yaohong Tan, Darwin Eton, Zhe Yang, M Georgina Uberti, Sen Li, Andrew Schulick, Hong Y. Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels. Stem cells (Dayton, Ohio). vol 26. issue 5. 2008-07-28. PMID:18308946. |
in conclusion, statin and sdf-1 additively enhance progenitor cell migration and proliferation and down-regulate epc apoptosis, resulting in improved reperfusion via activation of the akt/nos pathway and up-regulation of mmp-2 and mmp-9 expression. |
2008-07-28 |
2023-08-12 |
mouse |
Renold J Capocasale, Dorie A Makropoulos, Ram Achuthanandam, Nicole Stowell, John Quinn, Patricia A Rafferty, Joanne O'Brien, Eva Emmell, Peter J Bugelsk. Myelodysplasia and anemia of chronic disease in human tumor necrosis factor-alpha transgenic mice. Cytometry. Part A : the journal of the International Society for Analytical Cytology. vol 73. issue 2. 2008-05-07. PMID:18205195. |
in the bone marrow, we observed alterations in cell kinetics, decreased relative expression of transferrin receptor and increased apoptosis and cell death in several late precursor cell populations. |
2008-05-07 |
2023-08-12 |
mouse |
Steven H Zeise. Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB life. vol 59. issue 6. 2008-01-07. PMID:17613168. |
choline is critical during fetal development, when it alters dna methylation and thereby influences neural precursor cell proliferation and apoptosis. |
2008-01-07 |
2023-08-12 |
human |
Michael Epperly, Shunqian Jin, Suhua Nie, Shaonan Cao, Xichen Zhang, Darcy Franicola, Hong Wang, Mitchell P Fink, Joel S Greenberge. Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation. Radiation research. vol 168. issue 5. 2007-12-13. PMID:17973549. |
incubating il3-dependent mouse hematopoietic progenitor cell 32dcl3 cells before or after irradiation with 10 mm ep increased resistance to radiation as assessed by clonogenic radiation survival curves, decreased release of mitochondrial cytochrome c into the cytoplasm, and decreased apoptosis. |
2007-12-13 |
2023-08-12 |
mouse |
D Mocini, T Leone, M Tubaro, M Santini, M Penc. Structure, production and function of erythropoietin: implications for therapeutical use in cardiovascular disease. Current medicinal chemistry. vol 14. issue 21. 2007-11-29. PMID:17896976. |
it primarily acts on erythroid precursor cell at colony-forming units-erythroid stage inhibiting the apoptosis. |
2007-11-29 |
2023-08-12 |
human |
S Li, M J Ferguson, C J Hawkins, C Smith, N J Elwoo. Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal. Leukemia. vol 20. issue 7. 2007-09-26. PMID:16673017. |
retroviral expression of htert in the cytokine-dependent, human hematopoietic progenitor cell line, tf-1, resulted in the survival of cells following the withdrawal of cytokine, with protection from apoptosis, but did not promote unlimited replicative potential. |
2007-09-26 |
2023-08-12 |
human |
Li Zhou, You-ji Feng, Ming-wei Zhu, Wei Zhang, Hui-ming Ji. [Gene transfer of tumor necrosis factor related apoptosis inducing ligand to endothelial progenitor cell for ovarian cancer therapy]. Zhonghua fu chan ke za zhi. vol 40. issue 12. 2007-09-14. PMID:16412328. |
[gene transfer of tumor necrosis factor related apoptosis inducing ligand to endothelial progenitor cell for ovarian cancer therapy]. |
2007-09-14 |
2023-08-12 |
Not clear |
Li Zhou, You-ji Feng, Ming-wei Zhu, Wei Zhang, Hui-ming Ji. [Gene transfer of tumor necrosis factor related apoptosis inducing ligand to endothelial progenitor cell for ovarian cancer therapy]. Zhonghua fu chan ke za zhi. vol 40. issue 12. 2007-09-14. PMID:16412328. |
to express tumor necrosis factor related apoptosis inducing ligand (trail) protein using endothelial progenitor cell (epc) and observe antitumor activity of secreted trail in cell culture supernatant. |
2007-09-14 |
2023-08-12 |
Not clear |
Arthur J Sytkowsk. Does erythropoietin have a dark side? Epo signaling and cancer cells. Science's STKE : signal transduction knowledge environment. vol 2007. issue 395. 2007-09-05. PMID:17636183. |
erythropoietin (epo) stimulates red blood cell production by docking with its cognate receptor on the erythroid progenitor cell and triggering an array of signaling pathways that inhibit apoptosis and promote cell proliferation and differentiation. |
2007-09-05 |
2023-08-12 |
Not clear |
Qing-Xiang Zhou, Yi-Nü Li, Xing-Jia Shen, Yong-Zhu Yi, Yao-Zhou Zhang, Zhi-Fang Zhan. The scaleless wings mutant in Bombyx mori is associated with a lack of scale precursor cell differentiation followed by excessive apoptosis. Development genes and evolution. vol 216. issue 11. 2007-05-10. PMID:16773336. |
the scaleless wings mutant in bombyx mori is associated with a lack of scale precursor cell differentiation followed by excessive apoptosis. |
2007-05-10 |
2023-08-12 |
Not clear |
Fatih Uckun, Zahide Ozer, Alexei Vassile. Bruton's tyrosine kinase prevents activation of the anti-apoptotic transcription factor STAT3 and promotes apoptosis in neoplastic B-cells and B-cell precursors exposed to oxidative stress. British journal of haematology. vol 136. issue 4. 2007-04-24. PMID:17367410. |
similarly, while the btk-positive nalm-6 human leukaemic b-cell precursor cell line showed no stat3 activation after pv treatment and was exquisitely sensitive to pv-induced apoptosis, pv failed to induce apoptosis in btk-deficient ramos-1 human lymphoma b-cells that showed a robust stat3 response. |
2007-04-24 |
2023-08-12 |
human |
Ying Geng, Rizwan S Akhtar, John J Shacka, Barbara J Klocke, Jin Zhang, Xinbin Chen, Kevin A Rot. p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis. Journal of neuropathology and experimental neurology. vol 66. issue 1. 2007-02-15. PMID:17204938. |
p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis. |
2007-02-15 |
2023-08-12 |
mouse |
J Michelle Edwards, Jane E Bottenstei. Neuregulin 1 growth factors regulate proliferation but not apoptosis of a CNS neuronal progenitor cell line. Brain research. vol 1108. issue 1. 2006-12-06. PMID:16859650. |
neuregulin 1 growth factors regulate proliferation but not apoptosis of a cns neuronal progenitor cell line. |
2006-12-06 |
2023-08-12 |
rat |
D Perrotti, P Nevian. ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia. British journal of cancer. vol 95. issue 7. 2006-11-14. PMID:16953242. |
we recently reported that the activity of the tumour suppressor protein phosphatase 2a (pp2a) is markedly inhibited in blast crisis cml patient cells and that molecular or pharmacologic re-activation of pp2a phosphatase led to growth suppression, enhanced apoptosis, impaired clonogenic potential and decreased in vivo leukaemogenesis of imatinib-sensitive and -resistant (t315i included) cml-bc patient cells and/or bcr/abl+ myeloid progenitor cell lines. |
2006-11-14 |
2023-08-12 |
Not clear |
Min Shen, Qing Lan, Luoping Zhang, Stephen Chanock, Guilan Li, Roel Vermeulen, Stephen M Rappaport, Weihong Guo, Richard B Hayes, Martha Linet, Songnian Yin, Meredith Yeager, Robert Welch, Matthew S Forrest, Nathaniel Rothman, Martyn T Smit. Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity. Carcinogenesis. vol 27. issue 10. 2006-11-13. PMID:16728435. |
dsb may lead to chromosome aberrations, apoptosis and hematopoietic progenitor cell suppression. |
2006-11-13 |
2023-08-12 |
human |
Zhi-Yong Chen, Renaud Warin, Constance Tom Noguch. Erythropoietin and normal brain development: receptor expression determines multi-tissue response. Neuro-degenerative diseases. vol 3. issue 1-2. 2006-10-06. PMID:16909040. |
the ability for epo to stimulate progenitor cell proliferation and prevent apoptosis is critical for maintenance of the erythroid lineage, but is also observed in neural and muscle progenitor cells. |
2006-10-06 |
2023-08-12 |
mouse |