| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C D'Sa-Eipper, J R Leonard, G Putcha, T S Zheng, R A Flavell, P Rakic, K Kuida, K A Rot. DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3. Development (Cambridge, England). vol 128. issue 1. 2001-02-22. PMID:11092819. |
to define the molecular pathway regulating dna damage-induced neural precursor cell apoptosis, we have examined the effects of drug and gamma-irradiation-induced dna damage on telencephalic neural precursor cells derived from wild-type embryos and mice with targeted disruptions of apoptosis-associated genes. |
2001-02-22 |
2023-08-12 |
mouse |
| C D'Sa-Eipper, J R Leonard, G Putcha, T S Zheng, R A Flavell, P Rakic, K Kuida, K A Rot. DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3. Development (Cambridge, England). vol 128. issue 1. 2001-02-22. PMID:11092819. |
we found that dna damage-induced neural precursor cell apoptosis, both in vitro and in vivo, was critically dependent on p53 and caspase 9, but neither bax nor caspase 3 expression. |
2001-02-22 |
2023-08-12 |
mouse |
| C D'Sa-Eipper, J R Leonard, G Putcha, T S Zheng, R A Flavell, P Rakic, K Kuida, K A Rot. DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3. Development (Cambridge, England). vol 128. issue 1. 2001-02-22. PMID:11092819. |
neural precursor cell apoptosis was also unaffected by targeted disruptions of bclx and bcl2, and unlike neurotrophic factor-deprivation-induced neuronal apoptosis, was not associated with a detectable loss of cytochrome c from mitochondria. |
2001-02-22 |
2023-08-12 |
mouse |
| L Hagedorn, J Floris, U Suter, L Somme. Autonomic neurogenesis and apoptosis are alternative fates of progenitor cell communities induced by TGFbeta. Developmental biology. vol 228. issue 1. 2001-01-11. PMID:11087626. |
autonomic neurogenesis and apoptosis are alternative fates of progenitor cell communities induced by tgfbeta. |
2001-01-11 |
2023-08-12 |
Not clear |
| H Sindre, H Rollag, M K Olafsen, M Degré, K Hestda. Human cytomegalovirus induces apoptosis in the hematopoietic cell line MO7e. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 108. issue 3. 2000-04-28. PMID:10752692. |
in conclusion, hcmv and hcmv dense bodies are able to induce apoptosis in the myeloid progenitor cell line mo7e. |
2000-04-28 |
2023-08-12 |
human |
| C D'Sa-Eipper, K A Rot. Caspase regulation of neuronal progenitor cell apoptosis. Developmental neuroscience. vol 22. issue 1-2. 2000-04-11. PMID:10657704. |
caspase regulation of neuronal progenitor cell apoptosis. |
2000-04-11 |
2023-08-12 |
mouse |
| M W Epperly, J A Bray, P Esocobar, W L Bigbee, S Watkins, J S Greenberge. Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest. Radiation oncology investigations. vol 7. issue 6. 2000-03-14. PMID:10644056. |
overexpression of the human manganese superoxide dismutase (mnsod) transgene in subclones of murine hematopoietic progenitor cell line 32d cl 3 decreases irradiation-induced apoptosis but does not alter g2/m or g1/s phase cell cycle arrest. |
2000-03-14 |
2023-08-12 |
human |
| K A Roth, C Kuan, T F Haydar, C D'Sa-Eipper, K S Shindler, T S Zheng, K Kuida, R A Flavell, P Raki. Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 1. 2000-02-10. PMID:10618441. |
in contrast, caspase-3, but not bcl-x, deficiency changed the normal incidence of neuronal progenitor cell apoptosis, consistent with the lack of expression of bcl-x(l) in the proliferative population of the embryonic cortex. |
2000-02-10 |
2023-08-12 |
Not clear |
| M F Romano, A Lamberti, R Bisogni, C Garbi, A M Pagnano, P Auletta, P Tassone, M C Turco, S Venut. Amifostine inhibits hematopoietic progenitor cell apoptosis by activating NF-kappaB/Rel transcription factors. Blood. vol 94. issue 12. 2000-01-10. PMID:10590050. |
amifostine inhibits hematopoietic progenitor cell apoptosis by activating nf-kappab/rel transcription factors. |
2000-01-10 |
2023-08-12 |
human |
| M F Romano, A Lamberti, R Bisogni, C Garbi, A M Pagnano, P Auletta, P Tassone, M C Turco, S Venut. Amifostine inhibits hematopoietic progenitor cell apoptosis by activating NF-kappaB/Rel transcription factors. Blood. vol 94. issue 12. 2000-01-10. PMID:10590050. |
these findings indicate that the inhibition of hematopoietic progenitor cell apoptosis by amifostine requires the induction of nf-kappab/rel factors and that the latter can therefore exert an antiapoptotic activity in the hematopoietic progenitor cell compartment. |
2000-01-10 |
2023-08-12 |
human |
| J Wiemels, M T Smit. Enhancement of myeloid cell growth by benzene metabolites via the production of active oxygen species. Free radical research. vol 30. issue 2. 1999-06-14. PMID:10193577. |
benzene metabolite's enhancement of growth of myeloid cells through an active oxygen mechanism may be involved in a number of aspects of benzene toxicity, including enhanced granulocytic growth and differentiation, stimulation of gm-csf-induced colony formation, apoptosis inhibition, and stimulation of progenitor cell mitogenesis in the bone marrow. |
1999-06-14 |
2023-08-12 |
human |
| S Reid, A Ritchie, L Boring, J Gosling, S Cooper, G Hangoc, I F Charo, H E Broxmeye. Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2. Blood. vol 93. issue 5. 1999-03-18. PMID:10029580. |
enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, ccr2. |
1999-03-18 |
2023-08-12 |
mouse |
| K Antoku, Z Liu, D E Johnso. IL-3 withdrawal activates a CrmA-insensitive poly(ADP-ribose) polymerase cleavage enzyme in factor-dependent myeloid progenitor cells. Leukemia. vol 12. issue 5. 1998-05-29. PMID:9593265. |
to determine whether il-3 withdrawal leads to the activation of caspase proteases, known mediators of apoptosis, we studied proteolytic cleavage of the caspase substrate protein poly(adp-ribose) polymerase (parp) in two il3-dependent myeloid progenitor cell lines, 32d and fdcp-1. |
1998-05-29 |
2023-08-12 |
Not clear |
| Q Song, M F Mehler, J A Kessle. Bone morphogenetic proteins induce apoptosis and growth factor dependence of cultured sympathoadrenal progenitor cells. Developmental biology. vol 196. issue 1. 1998-05-14. PMID:9527885. |
this study examined the effects of bone morphogenetic proteins (bmps) in inducing apoptosis of mah cells, an immortalized sympathoadrenal progenitor cell line. |
1998-05-14 |
2023-08-12 |
Not clear |
| R Net. Modulation with cytokines of radiation injury: suggested mechanisms of action. Environmental health perspectives. vol 105 Suppl 6. 1998-04-09. PMID:9467064. |
in contrast, radiosensitizing effects may be due to inhibition of progenitor cycling (tgf-beta) or enhanced progenitor cell apoptosis (tgf-beta). |
1998-04-09 |
2023-08-12 |
mouse |
| C M Traycoff, A Orazi, A C Ladd, S Rice, J McMahel, E F Srou. Proliferation-induced decline of primitive hematopoietic progenitor cell activity is coupled with an increase in apoptosis of ex vivo expanded CD34+ cells. Experimental hematology. vol 26. issue 1. 1998-02-04. PMID:9430514. |
proliferation-induced decline of primitive hematopoietic progenitor cell activity is coupled with an increase in apoptosis of ex vivo expanded cd34+ cells. |
1998-02-04 |
2023-08-12 |
human |
| J R Par. Cytokine regulation of apoptosis in hematopoietic precursor cells. Current opinion in hematology. vol 3. issue 3. 1997-12-09. PMID:9372075. |
apoptosis (a programmed cell death pathway) has been identified as the key factor limiting hematopoietic precursor cell survival and cytokines have been demonstrated to induce or prevent apoptosis in a variety of hematopoietic precursor cell populations. |
1997-12-09 |
2023-08-12 |
Not clear |
| J R Par. Cytokine regulation of apoptosis in hematopoietic precursor cells. Current opinion in hematology. vol 3. issue 3. 1997-12-09. PMID:9372075. |
finally, the intracellular pathways of cytokine receptor-mediated control of apoptosis have begun to be unraveled, implicating specific intracellular receptor domains and protein kinases in the regulation of apoptosis and hematopoietic precursor cell survival. |
1997-12-09 |
2023-08-12 |
Not clear |
| R W Watson, O D Rotstein, J Parodo, R Bitar, D Hackam, J C Marshal. Granulocytic differentiation of HL-60 cells results in spontaneous apoptosis mediated by increased caspase expression. FEBS letters. vol 412. issue 3. 1997-09-11. PMID:9276475. |
functional maturation and susceptibility to apoptosis are both inducible and linked in this granulocyte precursor cell line. |
1997-09-11 |
2023-08-12 |
Not clear |
| M Z Ratajczak, J Ratajczak, W Marlicz, C H Pletcher, B Machalinski, J Moore, H Hung, A M Gewirt. Recombinant human thrombopoietin (TPO) stimulates erythropoiesis by inhibiting erythroid progenitor cell apoptosis. British journal of haematology. vol 98. issue 1. 1997-09-03. PMID:9233556. |
recombinant human thrombopoietin (tpo) stimulates erythropoiesis by inhibiting erythroid progenitor cell apoptosis. |
1997-09-03 |
2023-08-12 |
human |