| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei-Lan Liu, Chun-Liang Chen, Chia-Chung Lee, Cheng-Chi Wu, Teng-Hsu Hsu, Chang-Youh Tsai, Hsu-Shan Huang, Deh-Ming Chan. The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation. International journal of medical sciences. vol 14. issue 9. 2018-05-04. PMID:28824321. |
however, the cytotoxic effects of niclosamide obviously appeared at the effective concentrations for inhibiting osteoclastogenesis (0.5-1um) with increase of apoptosis through caspase-3 activation in osteoblast precursor cell line, mc3t3-e1. |
2018-05-04 |
2023-08-13 |
Not clear |
| Shawn David O'Connor, Omar Hoseá Cabrera, Joseph D Dougherty, Sukrit Singh, Brant Stephen Swiney, Patricia Salinas-Contreras, Nuri Bradford Farber, Kevin Kiyoshi Noguch. Dexmedetomidine protects against glucocorticoid induced progenitor cell apoptosis in neonatal mouse cerebellum. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 30. issue 18. 2018-04-24. PMID:27677376. |
dexmedetomidine protects against glucocorticoid induced progenitor cell apoptosis in neonatal mouse cerebellum. |
2018-04-24 |
2023-08-13 |
mouse |
| Wanwei Zheng, Zhongguang Luo, Jun Zhang, Pei Min, Wenshuai Li, Diannan Xu, Ziqiang Zhang, Panpan Xiong, Hong Liang, Jie Li. Neural precursor cell expressed, developmentally downregulated 8‑activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis. Molecular medicine reports. vol 15. issue 5. 2018-02-16. PMID:28447739. |
neural precursor cell expressed, developmentally downregulated 8‑activating enzyme inhibitor mln4924 sensitizes colorectal cancer cells to oxaliplatin by inducing dna damage, g2 cell cycle arrest and apoptosis. |
2018-02-16 |
2023-08-13 |
Not clear |
| Ayala Gover-Proaktor, Galit Granot, Saar Shapira, Oshrat Raz, Oren Pasvolsky, Arnon Nagler, Dorit L Lev, Aida Inbal, Ido Lubin, Pia Raanani, Avi Leade. Ponatinib reduces viability, migration, and functionality of human endothelial cells. Leukemia & lymphoma. vol 58. issue 6. 2018-01-12. PMID:27733071. |
pharmacological concentrations of ponatinib induced apoptosis, reduced migration, inhibited tube formation of huvecs, and had a negative effect on endothelial progenitor cell (epc) function. |
2018-01-12 |
2023-08-13 |
human |
| Filip Petković, Iain L Campbell, Berta Gonzalez, Bernardo Castellan. Astrocyte-targeted production of interleukin-6 reduces astroglial and microglial activation in the cuprizone demyelination model: Implications for myelin clearance and oligodendrocyte maturation. Glia. vol 64. issue 12. 2018-01-05. PMID:27535761. |
in addition, transgenic production of il-6 did not alter initial oligodendrocyte (ol) apoptosis and oligodendrocyte precursor cell recruitment to the lesion site, but it impaired early ol differentiation, possibly due to impaired removal of degraded myelin. |
2018-01-05 |
2023-08-13 |
mouse |
| Peng Zhang, Chunli Pei, Xi Wang, Jinyi Xiang, Bao-Fa Sun, Yongsheng Cheng, Xiaolong Qi, Marco Marchetti, Jia-Wei Xu, Ying-Pu Sun, Bruce A Edgar, Zengqiang Yua. A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size. Developmental cell. vol 43. issue 5. 2018-01-04. PMID:29207260. |
this regulation has significant effects on apoptosis, organ size, and progenitor cell proliferation. |
2018-01-04 |
2023-08-13 |
human |
| Kenneth Maies. Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders. British journal of clinical pharmacology. vol 82. issue 5. 2017-12-29. PMID:26469771. |
mtor governs the programmed cell death pathways of apoptosis and autophagy that can determine neuronal stem cell development, precursor cell differentiation, cell senescence, cell survival and ultimate cell fate. |
2017-12-29 |
2023-08-13 |
Not clear |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
studies have demonstrated that the high-mobility group 1b protein (hmgb1) could regulate endothelial progenitor cell (epc) homing, but the effect of hmgb1 on epc apoptosis and associated mechanisms are still unclear. |
2017-12-04 |
2023-08-13 |
Not clear |
| Xiaosong Chen, Liu Yan, Zhihui Guo, Zhaohong Chen, Ying Chen, Ming Li, Chushan Huang, Xiaoping Zhang, Liangwan Che. Adipose-derived mesenchymal stem cells promote the survival of fat grafts via crosstalk between the Nrf2 and TLR4 pathways. Cell death & disease. vol 7. issue 9. 2017-10-25. PMID:27607584. |
hypoxia-induced inflammatory cytokine, growth factor and nox1/4 upregulation, as well as increased ros production and apoptosis in adscs were dependent on tlr4 and nrf2, which also modulated the effect of adscs on promoting endothelial progenitor cell migration and angiogenesis. |
2017-10-25 |
2023-08-13 |
mouse |
| Angela Park, Juliana Barrera-Ramirez, Indee Ranasinghe, Sophie Pilon, Richmond Sy, Dean Fergusson, David S Alla. Use of Statins to Augment Progenitor Cell Function in Preclinical and Clinical Studies of Regenerative Therapy: a Systematic Review. Stem cell reviews and reports. vol 12. issue 3. 2017-10-20. PMID:26873165. |
hmg coa reductase inhibitors (statins) appear promising in blocking apoptosis, prolonging progenitor cell survival and improving their capacity to repair organ function. |
2017-10-20 |
2023-08-13 |
Not clear |
| Hainan Li, Jenny Liu, Yihan Wang, Zhiyao Fu, Maik Hüttemann, Terrence J Monks, Alex F Chen, Jie-Mei Wan. MiR-27b augments bone marrow progenitor cell survival via suppressing the mitochondrial apoptotic pathway in Type 2 diabetes. American journal of physiology. Endocrinology and metabolism. vol 313. issue 4. 2017-10-10. PMID:28698281. |
however, increased progenitor cell apoptosis in diabetes directly limits their success in the clinic. |
2017-10-10 |
2023-08-13 |
Not clear |
| Zhao Sun, Wenjie Yu, Maria Sanz Navarro, Mason Sweat, Steven Eliason, Thad Sharp, Huan Liu, Kerstin Seidel, Li Zhang, Myriam Moreno, Thomas Lynch, Nathan E Holton, Laura Rogers, Traci Neff, Michael J Goodheart, Frederic Michon, Ophir D Klein, Yang Chai, Adam Dupuy, John F Engelhardt, Zhi Chen, Brad A Amend. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development (Cambridge, England). vol 143. issue 22. 2017-09-11. PMID:27660324. |
the murine incisor develops initially but is absorbed independently of apoptosis owing to a lack of progenitor cell proliferation and differentiation. |
2017-09-11 |
2023-08-13 |
mouse |
| Guodong Tie, Jinglian Yan, Julia A Messina, Robert L Raffai, Louis M Messin. Inhibition of p38 Mitogen-Activated Protein Kinase Enhances the Apoptosis Induced by Oxidized Low-Density Lipoprotein in Endothelial Progenitor Cells. Journal of vascular research. vol 52. issue 6. 2017-09-05. PMID:27031525. |
oxldl has been shown to decrease endothelial progenitor cell (epc) number by inducing apoptosis. |
2017-09-05 |
2023-08-13 |
mouse |
| Kosuke Kaji, Valentina M Factor, Jesper B Andersen, Marian E Durkin, Akira Tomokuni, Jens U Marquardt, Matthias S Matter, Tanya Hoang, Elizabeth A Conner, Snorri S Thorgeirsso. DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration. Hepatology (Baltimore, Md.). vol 64. issue 2. 2017-07-17. PMID:26999257. |
the impact of dnmt1 knockdown was also analyzed in hepatic progenitor cell lines; proliferation, apoptosis, dna damage, and sphere formation were assessed. |
2017-07-17 |
2023-08-13 |
mouse |
| María S Bianchi, Stefanía Bianchi, Andrés Hernado-Insúa, Leandro M Martinez, Néstor Lago, Carlos Libertun, Norma A Chasseing, Alejandro D Montaner, Victoria A Lux-Lanto. Proposed mechanisms for oligonucleotide IMT504 induced diabetes reversion in a mouse model of immunodependent diabetes. American journal of physiology. Endocrinology and metabolism. vol 311. issue 2. 2017-06-21. PMID:27329801. |
we determined blood glucose, glucose tolerance, serum insulin, islet morphology, islet infiltration, serum cytokines, progenitor cell markers, immunomodulatory proteins, proliferation, apoptosis, and islet gene expression. |
2017-06-21 |
2023-08-13 |
mouse |
| Yiwei Zhang, Shelya X Zeng, Qian Hao, Hua L. Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner. Developmental biology. vol 423. issue 1. 2017-06-07. PMID:28118981. |
interestingly, deletion of mdm2 results in defects of embryonic endocrine pancreas development, followed by neonatal hyperglycemia and lethality, by inducing pancreatic progenitor cell apoptosis and inhibiting cell proliferation. |
2017-06-07 |
2023-08-13 |
mouse |
| Julia Köhn-Gaone, Benjamin J Dwyer, Candice A Grzelak, Gregory Miller, Nicholas A Shackel, Grant A Ramm, Geoffrey W McCaughan, Caryn L Elsegood, John K Olynyk, Janina E E Tirnitz-Parke. Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury. The American journal of pathology. vol 186. issue 7. 2017-05-12. PMID:27181403. |
markers of liver injury, including serum alanine transaminase levels, apoptosis, hepatic fat loading, and oxidative stress, as well as inflammatory, fibrogenic and liver progenitor cell responses, were assessed at days 3, 7, 14, 21, and 42. |
2017-05-12 |
2023-08-13 |
mouse |
| Viktoriya Y Rybalko, Chantal B Pham, Pei-Ling Hsieh, David W Hammers, Melissa Merscham-Banda, Laura J Suggs, Roger P Farra. Controlled delivery of SDF-1α and IGF-1: CXCR4(+) cell recruitment and functional skeletal muscle recovery. Biomaterials science. vol 3. issue 11. 2017-01-03. PMID:26247892. |
we hypothesized that sdf-1α will promote sustained stem cell recruitment to the site of muscle injury, while igf-i will induce progenitor cell differentiation to effectively restore muscle contractile function after tk-i/r injury while concurrently reducing apoptosis. |
2017-01-03 |
2023-08-13 |
Not clear |
| Subhayan Sur, Debolina Pal, Syamsundar Mandal, Anup Roy, Chinmay Kumar Pand. Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways. The Journal of nutritional biochemistry. vol 27. 2016-10-20. PMID:26386739. |
this restriction was associated with significantly reduced proliferation, increased apoptosis, decreased prevalence of hepatocyte progenitor cell (afp) and stem cell population (cd44) irrespective of egcg/tf treatments. |
2016-10-20 |
2023-08-13 |
mouse |
| Hsiao-Ya Tsai, Chih-Pei Lin, Po-Hsun Huang, Szu-Yuan Li, Jia-Shiong Chen, Feng-Yen Lin, Jaw-Wen Chen, Shing-Jong Li. Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways. Journal of diabetes research. vol 2016. 2016-10-05. PMID:26682233. |
we investigated whether coq10 can attenuate high glucose-induced endothelial progenitor cell (epc) apoptosis and clarified its mechanism. |
2016-10-05 |
2023-08-13 |
Not clear |