| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haci Ömer Osmanlıoğlu, Mustafa Nazıroğl. Resveratrol Modulates Diabetes-Induced Neuropathic Pain, Apoptosis, and Oxidative Neurotoxicity in Mice Through TRPV4 Channel Inhibition. Molecular neurobiology. 2024-07-08. PMID:38976129. |
resveratrol modulates diabetes-induced neuropathic pain, apoptosis, and oxidative neurotoxicity in mice through trpv4 channel inhibition. |
2024-07-08 |
2024-07-11 |
mouse |
| Jia He, Jia Zuo, Xiaochen Fan, Zhe L. Electro-acupuncture modulated miR-214 expression to prevent chondrocyte apoptosis and reduce pain by targeting BAX and TRPV4 in osteoarthritis rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-05-29. PMID:38808885. |
electro-acupuncture modulated mir-214 expression to prevent chondrocyte apoptosis and reduce pain by targeting bax and trpv4 in osteoarthritis rats. |
2024-05-29 |
2024-06-02 |
rat |
| Jia He, Jia Zuo, Xiaochen Fan, Zhe L. Electro-acupuncture modulated miR-214 expression to prevent chondrocyte apoptosis and reduce pain by targeting BAX and TRPV4 in osteoarthritis rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-05-29. PMID:38808885. |
the expression of microrna-214 (mir-214) and its downstream targets involved in apoptosis and nociception, bax and trpv4, were examined. |
2024-05-29 |
2024-06-02 |
rat |
| Jia He, Jia Zuo, Xiaochen Fan, Zhe L. Electro-acupuncture modulated miR-214 expression to prevent chondrocyte apoptosis and reduce pain by targeting BAX and TRPV4 in osteoarthritis rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-05-29. PMID:38808885. |
by suppressing pro-apoptotic bax and pro-nociceptive trpv4, this ea-induced mir-214 upregulation ameliorated articular pain and prevented chondrocyte apoptosis. |
2024-05-29 |
2024-06-02 |
rat |
| Wenhui Liu, Wenzhe Zhang, Chen Wang, Jiarun Song, Kaiyue Li, Xia Zhang, Xinyi Wu, Hui Gu. TRPV4 antagonist suppresses retinal ganglion cell apoptosis by regulating the activation of CaMKII and TNF-α expression in a chronic ocular hypertension rat model. International immunopharmacology. vol 130. 2024-03-08. PMID:38457929. |
trpv4 antagonist suppresses retinal ganglion cell apoptosis by regulating the activation of camkii and tnf-α expression in a chronic ocular hypertension rat model. |
2024-03-08 |
2024-03-11 |
rat |
| Wenhui Liu, Wenzhe Zhang, Chen Wang, Jiarun Song, Kaiyue Li, Xia Zhang, Xinyi Wu, Hui Gu. TRPV4 antagonist suppresses retinal ganglion cell apoptosis by regulating the activation of CaMKII and TNF-α expression in a chronic ocular hypertension rat model. International immunopharmacology. vol 130. 2024-03-08. PMID:38457929. |
this study aims to investigate the role of trpv4 in rgc apoptosis in a rat model of chronic ocular hypertension (coh) and the underlying molecular mechanism. |
2024-03-08 |
2024-03-11 |
rat |
| Wenhui Liu, Wenzhe Zhang, Chen Wang, Jiarun Song, Kaiyue Li, Xia Zhang, Xinyi Wu, Hui Gu. TRPV4 antagonist suppresses retinal ganglion cell apoptosis by regulating the activation of CaMKII and TNF-α expression in a chronic ocular hypertension rat model. International immunopharmacology. vol 130. 2024-03-08. PMID:38457929. |
trpv4 inhibition by the trpv4 antagonist hc-067047 (hc-067) suppressed rgc apoptosis and protected visual function. |
2024-03-08 |
2024-03-11 |
rat |
| Wenhui Liu, Wenzhe Zhang, Chen Wang, Jiarun Song, Kaiyue Li, Xia Zhang, Xinyi Wu, Hui Gu. TRPV4 antagonist suppresses retinal ganglion cell apoptosis by regulating the activation of CaMKII and TNF-α expression in a chronic ocular hypertension rat model. International immunopharmacology. vol 130. 2024-03-08. PMID:38457929. |
the trpv4 antagonist hc-067 might suppress rgc apoptosis by regulating the activation of camkii and inhibiting the production of tnf-α in the coh model. |
2024-03-08 |
2024-03-11 |
rat |
| Yasuhiro Yamamoto, Daisuke Hishikawa, Fumihito On. Trpv4-mediated apoptosis of Leydig cells induced by high temperature regulates sperm development and motility in zebrafish. Communications biology. vol 7. issue 1. 2024-01-13. PMID:38218950. |
in the trpv4 null mutant, neither leydig cell-specific apoptosis nor decreased sperm motility was observed under high temperature. |
2024-01-13 |
2024-01-16 |
mouse |
| Go Woon Choi, Mi-Lyang Kim, Kyung Rim Sun. Modulation of TRPV4-mediated TNF-α expression in Müller glia and subsequent RGC apoptosis by statins. Experimental eye research. 2024-01-06. PMID:38184223. |
trpv4 activation through gsk101 treatment induced gliosis of müller cells, and the conditioned media from activated müller cells was potent to induce rgc apoptosis. |
2024-01-06 |
2024-01-09 |
mouse |
| Xueqing Li, Kongli Lu, Suxiang Guo, Song Xue, Feng Lia. TRPV4 blockade alleviates endoplasmic reticulum stress mediated apoptosis in hypoxia-induced cardiomyocyte injury. Cellular signalling. 2023-11-19. PMID:37981067. |
trpv4 blockade alleviates endoplasmic reticulum stress mediated apoptosis in hypoxia-induced cardiomyocyte injury. |
2023-11-19 |
2023-11-29 |
Not clear |
| Yi Wang, Wei Zhang, Guozheng Xu, Changwei Shi, Xiang Wang, Jianfeng Qu, Hongmei Wang, Chunhua Li. The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse. Heliyon. vol 9. issue 7. 2023-07-17. PMID:37456002. |
the role of trpv4 in the regulation of retinal ganglion cells apoptosis in rat and mouse. |
2023-07-17 |
2023-08-14 |
mouse |
| Yi Wang, Wei Zhang, Guozheng Xu, Changwei Shi, Xiang Wang, Jianfeng Qu, Hongmei Wang, Chunhua Li. The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse. Heliyon. vol 9. issue 7. 2023-07-17. PMID:37456002. |
however, after trpv4 antagonist treatment, the expression of bax and caspase 9 decreased, and the apoptosis rate of rgcs decreased. |
2023-07-17 |
2023-08-14 |
mouse |
| Yi Wang, Wei Zhang, Guozheng Xu, Changwei Shi, Xiang Wang, Jianfeng Qu, Hongmei Wang, Chunhua Li. The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse. Heliyon. vol 9. issue 7. 2023-07-17. PMID:37456002. |
thus, trpv4 may affect the mitochondrial apoptosis pathway, such as bax and caspase 9, leading to the apoptosis of rgcs. |
2023-07-17 |
2023-08-14 |
mouse |
| Carlene Moor. The role of TRPV4 channels in cutaneous epithelia. Current topics in membranes. vol 89. 2022-10-09. PMID:36210147. |
trpv4 plays many crucial roles in skin homeostasis to affect an extensive range of processes such as temperature sensation, osmo-sensation, hair growth, cell apoptosis, skin barrier integrity, differentiation, nociception and itch. |
2022-10-09 |
2023-08-14 |
Not clear |
| Özgür Öcal, Aymer Coşar, Mustafa Nazıroğl. Amantadine Attenuated Hypoxia-Induced Mitochondrial Oxidative Neurotoxicity, Apoptosis, and Inflammation via the Inhibition of TRPM2 and TRPV4 Channels. Molecular neurobiology. 2022-04-03. PMID:35366734. |
amantadine attenuated hypoxia-induced mitochondrial oxidative neurotoxicity, apoptosis, and inflammation via the inhibition of trpm2 and trpv4 channels. |
2022-04-03 |
2023-08-13 |
Not clear |
| Ahmet Özşimşek, Mustafa Nazıroğl. The involvement of TRPV4 on the hypoxia-induced oxidative neurotoxicity and apoptosis in a neuronal cell line: Protective role of melatonin. Neurotoxicology. vol 87. 2021-11-22. PMID:34562506. |
the involvement of trpv4 on the hypoxia-induced oxidative neurotoxicity and apoptosis in a neuronal cell line: protective role of melatonin. |
2021-11-22 |
2023-08-13 |
Not clear |
| Qian Li, Yun Cheng, Shenghai Zhang, Xinghuai Sun, Jihong W. TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway. Journal of neuroinflammation. vol 18. issue 1. 2021-11-21. PMID:34789280. |
here, we investigated the effects of trpv4 on rgc apoptosis in a rat model of chronic ocular hypertension (coh), then examined the mechanism underlying these effects. |
2021-11-21 |
2023-08-13 |
rat |
| Yanyan Zhao, Jiaying Wang, Xuehui Li. TRPV4 induces apoptosis via p38 MAPK in human lung cancer cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 54. issue 12. 2021-10-22. PMID:34669779. |
trpv4 induces apoptosis via p38 mapk in human lung cancer cells. |
2021-10-22 |
2023-08-13 |
human |
| Yanyan Zhao, Jiaying Wang, Xuehui Li. TRPV4 induces apoptosis via p38 MAPK in human lung cancer cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 54. issue 12. 2021-10-22. PMID:34669779. |
inhibition of p38 mapk abolished the effects of trpv4 on cell proliferation, apoptosis, and migration in a549 cells. |
2021-10-22 |
2023-08-13 |
human |