Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Heyam I M Al-Astal, Maram Massad, Manaf AlMatar, Harith Eka. Cellular Functions of RNA-Binding Motif Protein 3 (RBM3): Clues in Hypothermia, Cancer Biology and Apoptosis. Protein and peptide letters. vol 23. issue 9. 2017-03-22. PMID:27364162. |
cellular functions of rna-binding motif protein 3 (rbm3): clues in hypothermia, cancer biology and apoptosis. |
2017-03-22 |
2023-08-13 |
human |
Sophorn Chip, Andrea Zelmer, Omolara O Ogunshola, Ursula Felderhoff-Mueser, Cordula Nitsch, Christoph Bührer, Sven Wellman. The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21527344. |
mild hypothermia (32°c) profoundly promoted rbm3 expression and rescued neuronal cells from forced apoptosis as studied in primary neurons, pc12 cells, and cortical organotypic slice cultures. |
2012-05-07 |
2023-08-12 |
Not clear |
Amy L Ferry, Peter W Vanderklish, Esther E Dupont-Versteegde. Enhanced survival of skeletal muscle myoblasts in response to overexpression of cold shock protein RBM3. American journal of physiology. Cell physiology. vol 301. issue 2. 2011-10-03. PMID:21593448. |
cell death pathways are implicated in the loss of muscle mass and therefore the role of rbm3 in muscle apoptosis in c(2)c(12) myoblasts was investigated in this study. |
2011-10-03 |
2023-08-12 |
Not clear |
Amy L Ferry, Peter W Vanderklish, Esther E Dupont-Versteegde. Enhanced survival of skeletal muscle myoblasts in response to overexpression of cold shock protein RBM3. American journal of physiology. Cell physiology. vol 301. issue 2. 2011-10-03. PMID:21593448. |
rbm3 overexpression reduced apoptosis and the collapse of the membrane potential in response to stsp. |
2011-10-03 |
2023-08-12 |
Not clear |
Amy L Ferry, Peter W Vanderklish, Esther E Dupont-Versteegde. Enhanced survival of skeletal muscle myoblasts in response to overexpression of cold shock protein RBM3. American journal of physiology. Cell physiology. vol 301. issue 2. 2011-10-03. PMID:21593448. |
these results indicate that increased rbm3 expression decreases muscle cell necrosis as well as apoptosis and therefore rbm3 could potentially serve as an intervention for the loss of muscle cell viability during muscle atrophy and muscle diseases. |
2011-10-03 |
2023-08-12 |
Not clear |
Sven Wellmann, Matthias Truss, Elisabeth Bruder, Luigi Tornillo, Andrea Zelmer, Karl Seeger, Christoph Bühre. The RNA-binding protein RBM3 is required for cell proliferation and protects against serum deprivation-induced cell death. Pediatric research. vol 67. issue 1. 2010-03-25. PMID:19770690. |
sirna-mediated rbm3 knockdown reduced cell viability and finally led to cell death, which did not involve caspase-3-mediated apoptosis, cell cycle arrest, or cox-2 regulation. |
2010-03-25 |
2023-08-12 |
human |
S M Sureban, S Ramalingam, G Natarajan, R May, D Subramaniam, K S Bishnupuri, A R Morrison, B K Dieckgraefe, D J Brackett, R G Postier, C W Houchen, S Anan. Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. Oncogene. vol 27. issue 33. 2008-08-19. PMID:18427544. |
we have also identified that rbm3 knockdown increases caspase-mediated apoptosis coupled with nuclear cyclin b1, and phosphorylated cdc25c, chk1 and chk2 kinases, implying that under conditions of rbm3 downregulation, cells undergo mitotic catastrophe. |
2008-08-19 |
2023-08-12 |
mouse |
Ivan Martinez, Jun Wang, Kenosha F Hobson, Robert L Ferris, Saleem A Kha. Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas. European journal of cancer (Oxford, England : 1990). vol 43. issue 2. 2007-04-09. PMID:17079134. |
the upregulated genes included those involved in cell proliferation (akr1c3) and transcription regulation (snapc1), while downregulated genes included those involved in apoptosis (clu) and rna processing (rbm3). |
2007-04-09 |
2023-08-12 |
human |