| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinzhou Zhu, Jingyi Yan, Catherine Bregere, Andrea Zelmer, Tessa Goerne, Josef P Kapfhammer, Raphael Guzman, Sven Wellman. RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury. Nature communications. vol 10. issue 1. 2019-12-30. PMID:31484925. |
here we show how rbm3 stimulates neuronal differentiation and inhibits hi-induced apoptosis in the two areas of persistent adult neurogenesis, the subventricular zone (svz) and the subgranular zone (sgz), while promoting neural stem/progenitor cell (nspc) proliferation after hi injury only in the sgz. |
2019-12-30 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
rbm3 expression is upregulated by nf-κb p65 activity, protecting cells from apoptosis, during mild hypothermia. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
the rna-binding protein rbm3, a cold shock protein whose expression is elevated under hypothermic conditions, plays an important role in cell survival; however, little is known about the mechanism underlying the mild hypothermia-mediated regulation of rbm3 expression and apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
here we show that the transcription factor nf-κb p65 is phosphorylated at ser276 and activates rbm3 gene transcription via binding to a particular element within the promoter region in response to induced hypothermia, elevating the protein expression, and suppressing apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
treatment with caffeic acid phenethyl ester (cape), a potent and specific inhibitor that suppresses the translocation of nf-κb p65 from the cytoplasm to the nucleus, resulted in decreased levels of rbm3 mrna and protein and increased incidence of apoptosis despite cells were cultured under hypothermic conditions. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
overexpression of rbm3 abolished the induction of apoptosis in cells treated with cape, indicating that nf-κb p65-upregulated rbm3 expression is necessary for the suppression of apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
in addition, experiments with cells overexpressing rbm3 supported the finding demonstrating that the mild hypothermia-mediated higher expression of rbm3 suppressed the induction of apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
conversely, experiments with cells deficient in rbm3 supported the finding demonstrating that the cape-mediated loss of rbm3 induced apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Ayako Ushio, Ko Et. RBM3 expression is upregulated by NF-κB p65 activity, protecting cells from apoptosis, during mild hypothermia. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29388696. |
these results suggest that nf-κb p65 is a critical mediator of mild hypothermia, to which cells are exposed as an extracellular environment, and a central inducer of rbm3 expression, which is responsible for preventing cells from apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
rna-binding protein rbm3 prevents no-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and mir-143. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
the cold-inducible protein rbm3 mediates the protective effects of cooling on apoptosis induced by various insults. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
however, whether rbm3 protects neural cells from no-induced apoptosis is unclear. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
this study aimed to investigate the neuroprotective effect of rbm3 on no-induced apoptosis in human sh-sy5y neuroblastoma cells. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
firstly, we demonstrated that mild hypothermia (32 °c) induces rbm3 expression and confers a potent neuroprotective effect on no-induced apoptosis, which was substantially diminished when rbm3 was silenced by sirna. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
moreover, overexpression of rbm3 exhibited a strong protective effect against no-induced apoptosis. |
2018-10-24 |
2023-08-13 |
human |
| Hai-Jie Yang, Fei Ju, Xin-Xin Guo, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Rui-Juan Zhuang, Bin-Bin Zhang, Xiang Shi, Zhi-Wei Feng, Mian Wan. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Scientific reports. vol 7. 2018-10-24. PMID:28134320. |
these findings suggest that rbm3 protects neuroblastoma cells from no-induced apoptosis by suppressing p38 signaling, which mediates apoptosis through mir-143 induction. |
2018-10-24 |
2023-08-13 |
human |
| Yun-Long Li, Jian Li, Chang-Sheng Li, Jing-Hui Li, Yu Meng, Huan-Min Yang, Shi-Ze L. [Effect of RNA binding motif protein 3 overexpression on Caspase 3 expression in swine testiclar cell under cold exposure]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 2. 2018-10-15. PMID:29931857. |
to investigate the change of apoptosis protein (caspase 3) expression when rna binding motif protein 3 (rbm3) overexpression in swine testicle (st) cell line under cold stress (32℃) condition. |
2018-10-15 |
2023-08-13 |
Not clear |
| Rui-Juan Zhuang, Jian Ma, Xiang Shi, Fei Ju, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Yan-Wen Ma, Mian Wang, Tong Li, Zhi-Wei Feng, Hai-Jie Yan. Cold-Inducible Protein RBM3 Protects UV Irradiation-Induced Apoptosis in Neuroblastoma Cells by Affecting p38 and JNK Pathways and Bcl2 Family Proteins. Journal of molecular neuroscience : MN. vol 63. issue 2. 2018-06-19. PMID:28831692. |
cold-inducible protein rbm3 protects uv irradiation-induced apoptosis in neuroblastoma cells by affecting p38 and jnk pathways and bcl2 family proteins. |
2018-06-19 |
2023-08-13 |
human |
| Rui-Juan Zhuang, Jian Ma, Xiang Shi, Fei Ju, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Yan-Wen Ma, Mian Wang, Tong Li, Zhi-Wei Feng, Hai-Jie Yan. Cold-Inducible Protein RBM3 Protects UV Irradiation-Induced Apoptosis in Neuroblastoma Cells by Affecting p38 and JNK Pathways and Bcl2 Family Proteins. Journal of molecular neuroscience : MN. vol 63. issue 2. 2018-06-19. PMID:28831692. |
however, whether mild hypothermia and rbm3 prevent neural cells from uv irradiation-elicited apoptosis is unclear. |
2018-06-19 |
2023-08-13 |
human |
| Rui-Juan Zhuang, Jian Ma, Xiang Shi, Fei Ju, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Yan-Wen Ma, Mian Wang, Tong Li, Zhi-Wei Feng, Hai-Jie Yan. Cold-Inducible Protein RBM3 Protects UV Irradiation-Induced Apoptosis in Neuroblastoma Cells by Affecting p38 and JNK Pathways and Bcl2 Family Proteins. Journal of molecular neuroscience : MN. vol 63. issue 2. 2018-06-19. PMID:28831692. |
conversely, the overexpression of rbm3 rescued sh-sy5y cells from uv-induced apoptosis, as indicated by the decreased levels of cleaved caspase-3 and parp, and increased cell survival. |
2018-06-19 |
2023-08-13 |
human |