| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhanrui Zhang, Hongyu Liu, Jun Che. [Role of Mitochondria in Ferroptosis and Its Relationship to Tumors]. Zhongguo fei ai za zhi = Chinese journal of lung cancer. vol 27. issue 10. 2024-12-04. PMID:39631835. |
ferroptosis is a recently discovered form of cell death that is distinct from apoptosis, characterized primarily by the accumulation of intracellular iron and increased levels of lipid peroxidation. |
2024-12-04 |
2024-12-07 |
Not clear |
| Asmaa R Mohamed, Nagui H Fares, Yomna I Mahmou. Morin Ameliorates Lipopolysaccharides-Induced Sepsis-Associated Encephalopathy and Cognitive Impairment in Albino Mice. Neurochemical research. vol 50. issue 1. 2024-11-16. PMID:39549093. |
this was accompanied with the augmentation of the total antioxidant capacity, as well as the suppression of tissue levels of the lipid peroxidation marker malondialdehyde, apoptosis (cleaved-caspase-3), glial fibrillary acidic protein, and the proinflammatory cytokine tumor necrosis factor. |
2024-11-16 |
2024-11-20 |
mouse |
| Mohammed Eleyan, Mohammed R Zughbur, Mohamed Hussien, Basim M Ayesh, Khairy A Ibrahi. Carvacrol modulates antioxidant enzymes, DNA integrity, and apoptotic markers in zearalenone-exposed fetal rat liver. Drug and chemical toxicology. 2024-11-13. PMID:39538112. |
surprisingly, co-treatment with crv significantly mitigated fetal hepatic lipid peroxidation, antioxidant disturbance, apoptosis, and dna damage after maternal exposure to zea. |
2024-11-13 |
2024-11-17 |
rat |
| Almeida M Mafalda, Cabrita Elsa, Laizé Vincent, Brionne Aurélien, Labbé Catherine, Fatsini Elvir. Cryopreservation did not affect spermatogonia global methylation profile in Senegalese sole (Solea senegalensis). Cryobiology. 2024-11-08. PMID:39515550. |
this study aimed to assess post-thawed spermatogonia quality by evaluating alterations in plasma membrane integrity, dna integrity (fragmentation and apoptosis), lipid peroxidation (malondialdehyde levels) and epigenetic modifications (dna methylation profile). |
2024-11-08 |
2024-11-17 |
Not clear |
| Fernando Macías, Miriam Ulloa, Carmen Clapp, Gonzalo Martínez de la Escalera, Edith Arnol. Prolactin protects hippocampal neurons against H2O2-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway. PloS one. vol 19. issue 11. 2024-11-05. PMID:39499702. |
prolactin reduced ros levels, lipid peroxidation, and apoptosis, and its effects were occluded by a specific prolactin receptor antagonist (g129r-hprl). |
2024-11-05 |
2024-11-08 |
mouse |
| Sifan Dong, Shiqi An, Qifan Liu, Xujia Wang, Yongmei Hu, An Jian. Study on the Synergistic Mechanism of Photodynamic Therapy Combined With Ferroptosis Inducer to Induce Ferroptosis in Cholangiocarcinoma. Lasers in surgery and medicine. 2024-10-29. PMID:39468974. |
photodynamic therapy (pdt) induced lipid peroxidation reaction can lead to necrosis and apoptosis of extrahepatic cholangiocarcinoma (ecc) cells, reducing the tumor load. |
2024-10-29 |
2024-10-31 |
Not clear |
| Vidya P Kumar, Yali Kong, Riana Dolland, Sandra R Brown, Kan Wang, Damian Dolland, David Mu, Milton L Brow. Exploring Angiotensin II and Oxidative Stress in Radiation-Induced Cataract Formation: Potential for Therapeutic Intervention. Antioxidants (Basel, Switzerland). vol 13. issue 10. 2024-10-26. PMID:39456460. |
this oxidative damage leads to protein aggregation, lipid peroxidation, and apoptosis, ultimately compromising lens transparency and contributing to cataract formation. |
2024-10-26 |
2024-10-29 |
Not clear |
| AbdElAziz A Nayl, Esmail M El-Fakharany, Ahmed I Abd-Elhamid, Wael A A Arafa, Ahmed H Alanazi, Ismail M Ahmed, Mohamed A Abdelgawad, Ashraf A Aly, Stefan Bräs. Alginate-modified graphene oxide anchored with lactoperoxidase as a novel bioactive nanocombination for colorectal cancer therapy. Scientific reports. vol 14. issue 1. 2024-10-22. PMID:39438495. |
our observations presented that the modified nanocombination of lpo may offer a novel remedy for treating colon tumors via induced apoptosis pathway, inflammation reduction, and immune response improvement. |
2024-10-22 |
2024-10-25 |
cattle |
| K Bontor, B Gabrye. Sulodexide protects endothelial cells against 4-hydroxynonenal-induced oxidative stress and glutathione-dependent redox imbalance by modulation of sestrin2/nuclear factor erythroid 2-related factor 2 pathway. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 4. 2024-10-17. PMID:39415523. |
the lipid peroxidation product 4-hydroxynonenal (hne) may be involved in vascular endothelial cell damage by induction of oxidative stress, apoptosis, and loss of redox homeostasis. |
2024-10-17 |
2024-10-19 |
human |
| Mustafa Cengiz, Bahri Gür, Fatma Gür, Varol Şahintürk, Alpaslan Bayrakdar, Ilknur Kulcanay Şahin, Sıla Appak Başkoy, Namık Bilici, Suzan Onur, Yağmur Kaya, İsa Kıran, Özge Yıldırım, Nur Banu Akkaya, Canan Vejselova Sezer, Adnan Ayhanc. The protective effects of selenium and boron on cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in rats. Heliyon. vol 10. issue 19. 2024-10-17. PMID:39416834. |
administration of cp leads to an increase in the levels of apoptotic markers (bax, caspase-3), the apoptotic signaling pathway (nrf2), oxidative stress indicators (tos, osi), lipid peroxidation markers (mpo, mda), inflammation levels (nf-kb, tnf-α, il-1β, il -6), liver function markers (alt, ast, alp), while apoptosis markers (bcl-2), apoptosis pathway (keap-1), oxidative stress indicator (tas), inflammation (il -10) and intracellular antioxidant defense system (sod, cat, gpx and gsh) decreased. |
2024-10-17 |
2024-10-19 |
rat |
| Feng Chen, Qianhui Li, Xiaomin Xu, Fei Wan. Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. vol 35. issue 10. 2024-10-16. PMID:39412359. |
cell activity, lipid peroxidation, apoptosis and the expression of markers related to ferroptosis pathway was determined. |
2024-10-16 |
2024-10-18 |
mouse |
| Wenjie Ma, Xiaotian Jiang, Ruipeng Jia, Yang L. Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies. Cell death discovery. vol 10. issue 1. 2024-10-09. PMID:39384767. |
ferroptosis, characterized by iron-ion-dependent lipid peroxidation, is a form of programmed cell death (pcd) distinct from apoptosis, autophagy, and necrosis. |
2024-10-09 |
2024-10-12 |
Not clear |
| Eline Biscop, Jana Baroen, Joey De Backer, Wim Vanden Berghe, Evelien Smits, Annemie Bogaerts, Abraham Li. Characterization of regulated cancer cell death pathways induced by the different modalities of non-thermal plasma treatment. Cell death discovery. vol 10. issue 1. 2024-09-30. PMID:39349444. |
both direct and indirect ntp treatment increased caspase 3/7 and annexin v expression, indicative of apoptosis, as well as lipid peroxidation, characteristic of ferroptosis. |
2024-09-30 |
2024-10-03 |
Not clear |
| Zhaoying Wu, Junwei Zou, Hao Xie, Jie Wang, Yong Huang, Fei Liu, Chungen Xin. LncRNA ALMS1-IT1 modulates ferroptosis and immune evasion in colorectal cancer through activating STAT3. Journal of cellular and molecular medicine. vol 28. issue 18. 2024-09-28. PMID:39334527. |
ferroptosis, a unique form of programmed cell death distinct from apoptosis and necrosis, is characterized by cellular damage resulting from iron-induced lipid peroxidation, leading to cell death. |
2024-09-28 |
2024-10-01 |
Not clear |
| Eun-Ju Jin, Yunju Jo, Shibo Wei, Manfredi Rizzo, Dongryeol Ryu, Karim Garian. Ferroptosis and iron metabolism in diabetes: Pathogenesis, associated complications, and therapeutic implications. Frontiers in endocrinology. vol 15. 2024-09-16. PMID:39279996. |
ferroptosis emerges as a novel mechanism of programmed cell death, distinct from apoptosis, necrosis, and autophagy, driven by iron-dependent lipid peroxidation accumulation and gpx4 downregulation. |
2024-09-16 |
2024-09-18 |
Not clear |
| Kazuhiro Tamura, Yoshinobu Tomita, Takumi Kanazawa, Hajime Shinohara, Masayoshi Sakano, Sachiko Ishibashi, Masumi Ikeda, Mayumi Kinoshita, Junko Minami, Kurara Yamamoto, Yuki Kato, Asuka Furukawa, Shigeo Haruki, Masanori Tokunaga, Yusuke Kinugasa, Morito Kurata, Masanobu Kitagawa, Kenichi Ohashi, Kouhei Yamamot. Lipid Peroxidation Regulators GPX4 and FSP1 as Prognostic Markers and Therapeutic Targets in Advanced Gastric Cancer. International journal of molecular sciences. vol 25. issue 17. 2024-09-14. PMID:39273151. |
ferroptosis is an intracellular iron-dependent cell death induced by the accumulation of lipid peroxidation, a mechanism different from conventional apoptosis and necrosis. |
2024-09-14 |
2024-09-16 |
Not clear |
| Gihan Mahmoud Eldeeb, Mokhtar Ibrahim Yousef, Yasser Mohamed Helmy, Hebatallah Mohammed Aboudeya, Shimaa A Mahmoud, Maher A Kame. The protective effects of chitosan and curcumin nanoparticles against the hydroxyapatite nanoparticles-induced neurotoxicity in rats. Scientific reports. vol 14. issue 1. 2024-09-09. PMID:39251717. |
our findings revealed significant neuroinflammation associated with elevated apoptosis, lipid peroxidation, oxidative dna damage and nitric oxide levels with significant decline in the antioxidant enzymes activities and glutathione (gsh) levels in hanps-exposed rats. |
2024-09-09 |
2024-09-13 |
rat |
| Zi-Yue Xi, Chuan-Yong Fan, Shuang Zhu, Gan-Yu Nie, Xin-Ran Xi, Ying-Ying Jiang, Yao Zhou, Yi-Hua Mei, Lu X. PAFerroptosis Combined with Metabolic Disturbance of Mito by p52-ZER6 for Enhanced Cancer Immunotherapy induced by Nano-Bacilliform-Enzyme. Advanced healthcare materials. 2024-08-22. PMID:39171764. |
the tannin of nbe as a mitochondrial (mito)-targeting guide overloads mitoros, and then metabolic disorder and lipid peroxidation of mito membrane occurs, thus leading to a novel death pathway called paferroptosis (pyroptosis, apoptosis, and ferroptosis). |
2024-08-22 |
2024-08-24 |
Not clear |
| Aram Ghalali, Fahd Alhamdan, Swapna Upadhyay, Koustav Ganguly, Kjell Larsson, Lena Palmberg, Mizanur Rahma. Contrasting effects of intracellular and extracellular human PCSK9 on inflammation, lipid alteration and cell death. Communications biology. vol 7. issue 1. 2024-08-13. PMID:39138259. |
pcsk9 inhibition affect biological pathways, induces lipid peroxidation, and higher level of apoptosis in response to staurosporine. |
2024-08-13 |
2024-08-16 |
human |
| Wei Hu, Ziqian Zhao, Jianxin Du, Jie Jiang, Minghao Yang, Maojin Tian, Peiqing Zha. Interferon signaling and ferroptosis in tumor immunology and therapy. NPJ precision oncology. vol 8. issue 1. 2024-08-10. PMID:39127858. |
in vitro experiments were conducted to measure the levels of ifn-γ, mda, and lpo, as well as tumor cell viability and apoptosis. |
2024-08-10 |
2024-08-13 |
mouse |