| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Murayam. High-concentration of epidermal growth-factor induces apoptosis in breast and esophageal cancer-cells transplanted into nude-mice. Oncology reports. vol 1. issue 6. 2012-10-02. PMID:21607490. |
in situ apoptosis detection was performed using apop tag(tm) in situ apoptosis detection kit peroxidase. |
2012-10-02 |
2023-08-12 |
mouse |
| Xingang Zhang, Ke Tao, Taiping Ho. Investigation of 1-(4-morpholinophenyl)-3-(4-fluorophenyl)-propenone and 1-(4-morpholinophenyl)-3-(3-fluorophenyl)-propenone as new apoptosis inducers on Spodoptera frugiperda (Sf9) cells. Toxicology mechanisms and methods. vol 22. issue 4. 2012-08-27. PMID:22339240. |
compared to the controls, the significant over-expression of caspase-3 in treated cells was measured by caspase-3 activity kit, and the loss of mitochondrial membrane potential (ΔΨm) was detected in apoptosis cells. |
2012-08-27 |
2023-08-12 |
Not clear |
| Kuiran Liu, Tianda Feng, Jie Liu, Ming Zhong, Shulan Zhan. Silencing of the DEK gene induces apoptosis and senescence in CaSki cervical carcinoma cells via the up-regulation of NF-κB p65. Bioscience reports. vol 32. issue 3. 2012-07-16. PMID:22390170. |
the proliferation activity of cells were measured using an mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazolium bromide] assay, cell apoptosis was measured using an annexin v/pi (propidium iodide) kit, the cell cycle was analysed by flow cytometry and cell senescence was detected using senescence β-galactosidase staining. |
2012-07-16 |
2023-08-12 |
human |
| Qing Li, Maiko Kobayashi, Tomoyuki Kawad. Mechanism of ziram-induced apoptosis in human T lymphocytes. Archives of toxicology. vol 86. issue 4. 2012-07-10. PMID:22159898. |
disruption to mitochondrial transmembrane potential was determined with a mitolight(™) apoptosis detection kit. |
2012-07-10 |
2023-08-12 |
human |
| Hao Li, Lulu Hui, Wenlin X. miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. Acta biochimica et biophysica Sinica. vol 44. issue 3. 2012-07-10. PMID:22285729. |
apoptotic cells were quantitatively detected using annexin v/fitc and pi apoptosis detection kit. |
2012-07-10 |
2023-08-12 |
Not clear |
| b' Lenka Gibalov\\xc3\\xa1, M\\xc3\\xa1rio Sere\\xc5\\xa1, Andrej Rusn\\xc3\\xa1k, Peter Ditte, Martina Labudov\\xc3\\xa1, Branislav Uhr\\xc3\\xadk, Jaromir Pastorek, J\\xc3\\xa1n Sedl\\xc3\\xa1k, Albert Breier, Zdenka Sulov\\xc3\\xa. P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation. Toxicology in vitro : an international journal published in association with BIBRA. vol 26. issue 3. 2012-06-26. PMID:22269388.' |
cispt induced a more pronounced entry into apoptosis in s than r and t cells, which was measured using the annexin-v/propidium iodide apoptosis kit. |
2012-06-26 |
2023-08-12 |
human |
| Kwang Sik Suh, Seungjoon Oh, Jeong-Taek Woo, Sung-Woon Kim, Jin-Woo Kim, Young Seol Kim, Suk Cho. Apigenin attenuates 2-deoxy-D-ribose-induced oxidative cell damage in HIT-T15 pancreatic β-cells. Biological & pharmaceutical bulletin. vol 35. issue 1. 2012-06-15. PMID:22223348. |
time- and dose-dependent cell viability was monitored using a cell counting kit (cck-8), while the induction of apoptosis was analyzed using a cell death enzyme-linked immunosorbent assay (elisa) kit. |
2012-06-15 |
2023-08-12 |
Not clear |
| Cui Zhang, Guosheng Lin, Weiguo Wan, Xuyon Li, Bin Zeng, Bo Yang, Congxin Huan. Resveratrol, a polyphenol phytoalexin, protects cardiomyocytes against anoxia/reoxygenation injury via the TLR4/NF-κB signaling pathway. International journal of molecular medicine. vol 29. issue 4. 2012-05-29. PMID:22246136. |
in order to evaluate cardiomyocyte damage, cell viability, lactate dehydrogenase (ldh) release, caspase-3 activity, and apoptosis were analyzed by the cell counting kit (cck)-8 assay, colorimetric method and flow cytometry, respectively. |
2012-05-29 |
2023-08-12 |
rat |
| Shoubin Gu, Jinhai H. Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells. Molecules (Basel, Switzerland). vol 17. issue 1. 2012-05-01. PMID:22231496. |
induction of apoptosis was evidenced by apoptotic body appearance and annexin v-fitc/pi apoptosis detection kit. |
2012-05-01 |
2023-08-12 |
human |
| Jiayue Cheng, Kemei Peng, Erhui Jin, Yong Zhang, Yan Liu, Ningbo Zhang, Hui Song, Huazhen Liu, Zhonglin Tan. Effect of additional boron on tibias of African ostrich chicks. Biological trace element research. vol 144. issue 1-3. 2012-04-27. PMID:21461669. |
we also analyzed the apoptosis status of paraffin sections using a tunel kit and examined serum levels of leptin and estradiol (e(2)). |
2012-04-27 |
2023-08-12 |
chicken |
| Karina Elisa Machado, Kely Navakoski de Oliveira, Lorena Santos-Bubniak, Marley Aparecida Licínio, Ricardo José Nunes, Maria Cláudia Santos-Silv. Evaluation of apoptotic effect of cyclic imide derivatives on murine B16F10 melanoma cells. Bioorganic & medicinal chemistry. vol 19. issue 21. 2012-04-26. PMID:21964182. |
then the mechanism involved on the death route (necrosis or apoptosis) was evaluated the by bromide and acridine orange method and by an annexin v-fitc apoptosis detection kit. |
2012-04-26 |
2023-08-12 |
Not clear |
| Giuseppe Floris, Maria Debiec-Rychter, Agnieszka Wozniak, Cristiana Stefan, Emmanuel Normant, Gavino Faa, Kathleen Machiels, Ulla Vanleeuw, Raf Sciot, Patrick Schöffsk. The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors. Molecular cancer therapeutics. vol 10. issue 10. 2012-04-13. PMID:21825009. |
we evaluated tumor volume, proliferation and apoptosis, kit expression and activation, as well as adverse events during treatment. |
2012-04-13 |
2023-08-12 |
mouse |
| Jie Cheng, Liling Tang, Deyou Xiao, Fangyi Jiang, Jianfei Wang, Yan Mi, Chenguo Yao, Caixin Su. [Effects of electric pulses on liver cancer cells: apoptosis induction and decrease of mitochondrial transmembrane potential]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 28. issue 3. 2012-04-09. PMID:21774199. |
annexin v-fitc kit and flow cytometry were used to study the apoptosis of treated cells. |
2012-04-09 |
2023-08-12 |
Not clear |
| Ze-Jian Wang, Bin Zhou, Wen-Wei Mao, Ming Yi. Overexpression of 5-lipoxygenase increases the neuronal vulnerability of PC12 cells to Aβ₄₂. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 131. issue 12. 2012-03-06. PMID:22129883. |
cell apoptosis rates induced by aβ(42) were determined using an apo-brddu kit. |
2012-03-06 |
2023-08-12 |
Not clear |
| T Sliwinski, L Markiewicz, P Rusin, J Kabzinski, L Dziki, J Milonski, J Olszewski, J Blaszczyk, J Szemraj, I Majstere. Impaired nucleotide excision repair pathway as a possible factor in pathogenesis of head and neck cancer. Mutation research. vol 716. issue 1-2. 2012-02-07. PMID:21875606. |
mtt assay was used to analyse cell viability and the annexin v-fitc kit specific for kinase-3 was employed to determine apoptosis after treating the cells with uv-radiation at dose range from 0.5 to 60j/m(2). |
2012-02-07 |
2023-08-12 |
Not clear |
| Amalia Azzariti, Anna E Quatrale, Letizia Porcelli, Nicola A Colabufo, Mariangela Cantore, Giuseppe Cassano, Giuseppe Gasparre, Giuseppina Iannelli, Stefania Tommasi, Maria A Panaro, Angelo Paradis. MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment. European journal of pharmacology. vol 670. issue 1. 2012-02-06. PMID:21925160. |
in breast and colon cancer cell lines, cell growth and apoptosis were measured by mtt assay and dna laddering elisa kit, respectively. |
2012-02-06 |
2023-08-12 |
Not clear |
| Wei Zhang, Bao-An Chen, Wen Bao, Jian Cheng, Yan Sun, Jie Cheng, Min Zhang, Xiao-Min Zhang, Yan Che. [Effects of hyperbaric oxygen combined with adriamycin in inducing apoptosis of K562/A02 cells]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 3. 2012-01-19. PMID:21729536. |
the cell apoptosis and expression of caspase-3 activity were analyzed by flow cytometry and transmission electron microscopy; the expression levels of hif-1α, bcl-2 and bax mrna were detected by quantitative real time pcr; the caspase 8 activity was determined by using caspase 8 kit; the expression level of p-gp was detected by western blot. |
2012-01-19 |
2023-08-12 |
Not clear |
| Fang Li, Jing Sun, Huaishi Zhu, Xuejun Wen, Chao Lin, Donglu Sh. Preparation and characterization novel polymer-coated magnetic nanoparticles as carriers for doxorubicin. Colloids and surfaces. B, Biointerfaces. vol 88. issue 1. 2012-01-05. PMID:21764271. |
besides, influence of drug-loaded nanoparticles on in vitro cytotoxicity was determined by mtt assay, while cellular apoptosis was detected by annexin v-fitc apoptosis detection kit. |
2012-01-05 |
2023-08-12 |
Not clear |
| Feng Geng, Kun Song, James Z Xing, Cunzhong Yuan, Shi Yan, Qifeng Yang, Jie Chen, Beihua Kon. Thio-glucose bound gold nanoparticles enhance radio-cytotoxic targeting of ovarian cancer. Nanotechnology. vol 22. issue 28. 2011-12-19. PMID:21654036. |
the presence of reactive oxygen species (ros) was determined using cm-h2-dcfda confocal microscopy and cell apoptosis was determined by an annexin v-fitc/propidium iodide (pi) kit with flow cytometry. |
2011-12-19 |
2023-08-12 |
human |
| Gang Cui, Zhen Li, Bai Shao, Li Zhao, Yanfeng Zhou, Ting Lu, Junxiang Wang, Xioayong Shi, Jinjin Wang, Gang Zuo, Weiwei Zhu, Aiguo She. Clinical and biological significance of nemo-like kinase expression in glioma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:21177110. |
we also analyzed the effect of overexpression of nlk on cell apoptosis using a cell counting kit and western blot analysis. |
2011-12-05 |
2023-08-12 |
human |