Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
in our study, we investigated the mechanism leading to apoptosis in ht-29 cells in response to tnf-alpha and ligation of fas ag. |
1995-12-14 |
2023-08-12 |
Not clear |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
ht-29 displayed a dual response to tnf-alpha and fas ag ligation: in combination with ifn-gamma, ht-29 cells underwent apoptosis, whereas independently, these factors stimulated secretion of il-8. |
1995-12-14 |
2023-08-12 |
Not clear |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
we used this model of immune-mediated epithelial cell injury to elucidate the signals leading to apoptosis in response to tnf-alpha and fas ag ligation compared with the signals leading to induction of il-8 secretion. |
1995-12-14 |
2023-08-12 |
Not clear |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
the experiments presented here demonstrate that fas ag ligation alone led to production of il-8 by colonic epithelial cells and represented another function mediated by fas ag in addition to apoptosis. |
1995-12-14 |
2023-08-12 |
Not clear |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
specifically, new gene expression and protein synthesis were not necessary for tnf-alpha- and fas ag-mediated apoptosis, but were necessary for tnf-alpha- and fas ag-mediated il-8 secretion. |
1995-12-14 |
2023-08-12 |
Not clear |
M T Abreu-Martin, A Vidrich, D H Lynch, S R Targa. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 9. 1995-12-14. PMID:7594569. |
in spite of the similarities between these two agonists, the kinetics of apoptosis via fas ag were significantly more rapid than through the tnf-alpha receptor and serve to distinguish these two signals. |
1995-12-14 |
2023-08-12 |
Not clear |
M Aftabuddin, I Yamadori, T Yoshino, E Kondo, T Akag. Correlation between the number of apoptotic cells and expression of the apoptosis-related antigens Fas, Le(y) and bcl-2 protein in non-Hodgkin's lymphomas. Pathology international. vol 45. issue 6. 1995-12-13. PMID:7581933. |
apoptosis was visually quantified by the in situ end-labeling (isel) method, and the expression of fas, le(y) antigens and bcl-2 protein was examined by immunohistochemistry. |
1995-12-13 |
2023-08-12 |
Not clear |
L Tuosto, M S Gilardini Montani, S Lorenzetti, E Cundari, S Moretti, G Lombardi, E Piccolell. Differential susceptibility to monomeric HIV gp120-mediated apoptosis in antigen-activated CD4+ T cell populations. European journal of immunology. vol 25. issue 10. 1995-12-12. PMID:7589091. |
to investigate the different susceptibility to gp120 induced apoptosis of primary cd4+ and t cell clones further, the number of membrane cd4 molecules and their affinity for gp120, together with bcl-2 and fas expression, were studied. |
1995-12-12 |
2023-08-12 |
Not clear |
K B Onel, C L Tucek-Szabo, D Ashany, E Lacy, J Nikolic-Zugic, K B Elko. Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell ontogeny. European journal of immunology. vol 25. issue 10. 1995-12-12. PMID:7589095. |
in addition, although fas did not appear to play a direct role in apoptosis mediated by cross-linking of sig with anti-igm, anti-fasr and sublethal concentrations of anti-ig were additive in the induction of apoptosis in the early b cell line wehi 231. |
1995-12-12 |
2023-08-12 |
mouse |
N Rosenblatt, K U Hartmann, F Loo. Interactions of B6 wild and B6 gld cells engrafted within athymic nude beige recipients. Autoimmunity. vol 20. issue 1. 1995-12-07. PMID:7578865. |
the murine gld mutation is targetted to the gene coding for the ligand of the fas receptor for apoptosis. |
1995-12-07 |
2023-08-12 |
mouse |
J P Maciejewski, C Selleri, T Sato, S Anderson, N S Youn. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia. British journal of haematology. vol 91. issue 1. 1995-12-04. PMID:7577642. |
interferon-gamma (ifn-gamma) and tumour necrosis factor-alpha (tnf-alpha), potent inhibitors of haemopoiesis, enhance fas receptor expression on bone marrow (bm) cd34+ cells, and both cytokines render haemopoietic progenitor cells susceptible to fas-mediated inhibition of colony formation due to the induction of apoptosis. |
1995-12-04 |
2023-08-12 |
Not clear |
P Garrone, E M Neidhardt, E Garcia, L Galibert, C van Kooten, J Bancherea. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. The Journal of experimental medicine. vol 182. issue 5. 1995-12-04. PMID:7595197. |
fas ligation induces apoptosis of cd40-activated human b lymphocytes. |
1995-12-04 |
2023-08-12 |
human |
P Garrone, E M Neidhardt, E Garcia, L Galibert, C van Kooten, J Bancherea. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. The Journal of experimental medicine. vol 182. issue 5. 1995-12-04. PMID:7595197. |
taken together, the present results show that engagement of cd40 antigen on b cells induces fas expression and sensitizes them to fas-mediated apoptosis. |
1995-12-04 |
2023-08-12 |
human |
D P Hughes, I N Crisp. A naturally occurring soluble isoform of murine Fas generated by alternative splicing. The Journal of experimental medicine. vol 182. issue 5. 1995-12-04. PMID:7595210. |
in vitro, p815 mastocytoma cells transfected with fas b become resistant to fas ligand-induced apoptosis, and the resistance is mediated by a secreted product of the transfected cells. |
1995-12-04 |
2023-08-12 |
mouse |
D P Hughes, I N Crisp. A naturally occurring soluble isoform of murine Fas generated by alternative splicing. The Journal of experimental medicine. vol 182. issue 5. 1995-12-04. PMID:7595210. |
in vivo, fas beta mrna expression is correlated inversely with apoptosis among subsets of intrahepatic t lymphocytes, a cell population in which activation-induced t cell apoptosis occurs. |
1995-12-04 |
2023-08-12 |
mouse |
D P Hughes, I N Crisp. A naturally occurring soluble isoform of murine Fas generated by alternative splicing. The Journal of experimental medicine. vol 182. issue 5. 1995-12-04. PMID:7595210. |
we propose that fas b is a new cytokine that acts physiologically to limit apoptosis induced by fas ligand. |
1995-12-04 |
2023-08-12 |
mouse |
M Hane, B Lowin, M Peitsch, K Becker, J Tschop. Interaction of peptides derived from the Fas ligand with the Fyn-SH3 domain. FEBS letters. vol 373. issue 3. 1995-11-30. PMID:7589480. |
interaction of the widely expressed fas with its membrane-bound ligand (fasl) leads to rapid cell death via apoptosis. |
1995-11-30 |
2023-08-12 |
Not clear |
B Kneitz, T Herrmann, S Yonehara, A Schimp. Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589128. |
in contrast to cells from il-2-producing littermates, they do not exhibit fas-induced apoptosis when cultured on anti-fas antibody-coated plates, although fas expression by il-2-deficient cells is normal or even elevated compared to the il-2-producing control cells. |
1995-11-28 |
2023-08-12 |
mouse |
Z Moukrim, A Achou. Cytotoxic T lymphocytes specific for the synthetic VEINCTR peptide, a sequence found within the Fas molecule and env gp120 in the blood of HIV-1 seropositive individuals. Cellular and molecular biology (Noisy-le-Grand, France). vol 41. issue 3. 1995-11-27. PMID:7580839. |
the ctl activity was directed against autologous target cells presenting the heptapeptide which is site located in the fas molecule, known to be functionally involved in t-cell apoptosis. |
1995-11-27 |
2023-08-12 |
human |
H Koizumi, M Wakisaka, K Nakada, T Takakuwa, T Fujioka, N Yamate, T Uchikosh. Demonstration of apoptosis in neuroblastoma and its relationship to tumour regression. Virchows Archiv : an international journal of pathology. vol 427. issue 2. 1995-11-27. PMID:7582247. |
immunostaining of the fas receptor for apoptosis demonstrated that the tumour cells expressed this molecule on their cell surfaces. |
1995-11-27 |
2023-08-12 |
Not clear |