| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Takemura, K Murakami, H Miyazato, K Yagi, K Yoshiok. Expression of Fas antigen and Bcl-2 in human glomerulonephritis. Kidney international. vol 48. issue 6. 1996-03-27. PMID:8587248. |
to understand the regulatory mechanism of apoptosis in human glomerulonephritis, we examined the expression of fas antigen (cd95) and bcl-2 in five normal human kidney specimens and 80 tissues from patients with several types of glomerular diseases. |
1996-03-27 |
2023-08-12 |
human |
| R De Maria, M Boirivant, M G Cifone, P Roncaioli, M Hahne, J Tschopp, F Pallone, A Santoni, R Test. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation. The Journal of clinical investigation. vol 97. issue 2. 1996-03-05. PMID:8567950. |
the expression and function of fas (cd95/apo-1), a cell surface receptor directly responsible for triggering cell death by apoptosis, was investigated on human t lymphocytes resident within the intestinal lamina propria, a major site of antigen challenge and persistent lymphocyte activation. |
1996-03-05 |
2023-08-12 |
human |
| R De Maria, M Boirivant, M G Cifone, P Roncaioli, M Hahne, J Tschopp, F Pallone, A Santoni, R Test. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation. The Journal of clinical investigation. vol 97. issue 2. 1996-03-05. PMID:8567950. |
importantly, whereas fas cross-linking did not result in apoptosis induction in peripheral blood t lymphocytes (t-pbl), fas was found to be fully effective in generating the apoptotic signal in t-lpl. |
1996-03-05 |
2023-08-12 |
human |
| R De Maria, M Boirivant, M G Cifone, P Roncaioli, M Hahne, J Tschopp, F Pallone, A Santoni, R Test. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation. The Journal of clinical investigation. vol 97. issue 2. 1996-03-05. PMID:8567950. |
these data indicate that t-lpl constitutively express both fas and fasl and that fas cross-linking generates signals resulting in sphingomyelin hydrolysis and apoptosis, outlining a potential mechanism involved in intestinal tolerance. |
1996-03-05 |
2023-08-12 |
human |
| J Kajstura, W Cheng, K Reiss, W A Clark, E H Sonnenblick, S Krajewski, J C Reed, G Olivetti, P Anvers. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Laboratory investigation; a journal of technical methods and pathology. vol 74. issue 1. 1996-03-04. PMID:8569201. |
the enhanced expression of fas may be implicated in the activation of apoptosis in spite of the increase in bcl-2, which tends to preserve cell survival. |
1996-03-04 |
2023-08-12 |
rat |
| K M Latinis, G A Koretzk. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood. vol 87. issue 3. 1996-03-01. PMID:8562955. |
fas ligation induces apoptosis and jun kinase activation independently of cd45 and lck in human t cells. |
1996-03-01 |
2023-08-12 |
human |
| K M Latinis, G A Koretzk. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood. vol 87. issue 3. 1996-03-01. PMID:8562955. |
although prior studies suggest a role for protein tyrosine kinases and phosphatases in fas signaling, we report here that fas ligation induces apoptosis in t cells deficient in either cd45 or lck. |
1996-03-01 |
2023-08-12 |
human |
| K M Latinis, G A Koretzk. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood. vol 87. issue 3. 1996-03-01. PMID:8562955. |
we show that stimulation with a synthetic ceramide analog results in jnk activation as well as apoptosis, suggesting ceramide release occurs proximal to jnk activation in fas signaling. |
1996-03-01 |
2023-08-12 |
human |
| K M Latinis, G A Koretzk. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood. vol 87. issue 3. 1996-03-01. PMID:8562955. |
our data suggest that although cd45 and lck are not required for fas signaling, jnk activation may play an important role transducing distal signals that lead to apoptosis after fas ligation. |
1996-03-01 |
2023-08-12 |
human |
| M Tsuboi, K Eguchi, A Kawakami, N Matsuoka, Y Kawabe, T Aoyagi, K Maeda, S Nagatak. Fas antigen expression on synovial cells was down-regulated by interleukin 1 beta. Biochemical and biophysical research communications. vol 218. issue 1. 1996-03-01. PMID:8573146. |
recent reports revealed that fas antigen is functionally expressed on human synovial cells and apoptosis can be induced in these cells by anti-fas antibody. |
1996-03-01 |
2023-08-12 |
human |
| M Tsuboi, K Eguchi, A Kawakami, N Matsuoka, Y Kawabe, T Aoyagi, K Maeda, S Nagatak. Fas antigen expression on synovial cells was down-regulated by interleukin 1 beta. Biochemical and biophysical research communications. vol 218. issue 1. 1996-03-01. PMID:8573146. |
we examined the effect of interleukin 1 beta (il-1 beta) on fas antigen-mediated apoptosis on human synovial cells in vitro. |
1996-03-01 |
2023-08-12 |
human |
| M Tsuboi, K Eguchi, A Kawakami, N Matsuoka, Y Kawabe, T Aoyagi, K Maeda, S Nagatak. Fas antigen expression on synovial cells was down-regulated by interleukin 1 beta. Biochemical and biophysical research communications. vol 218. issue 1. 1996-03-01. PMID:8573146. |
in contrast, pretreatment of synovial cells with il-1 beta protected these cells against fas antigen-mediated apoptosis. |
1996-03-01 |
2023-08-12 |
human |
| M Tsuboi, K Eguchi, A Kawakami, N Matsuoka, Y Kawabe, T Aoyagi, K Maeda, S Nagatak. Fas antigen expression on synovial cells was down-regulated by interleukin 1 beta. Biochemical and biophysical research communications. vol 218. issue 1. 1996-03-01. PMID:8573146. |
our results suggest that il-1 beta inhibits fas antigen-mediated apoptosis of synovial cells and may perpetuate the hyperplasia of the synovium in patients with rheumatoid arthritis. |
1996-03-01 |
2023-08-12 |
human |
| T Nishimura, H Akiyama, S Yonehara, H Kondo, K Ikeda, M Kato, E Iseki, K Kosak. Fas antigen expression in brains of patients with Alzheimer-type dementia. Brain research. vol 695. issue 2. 1996-02-27. PMID:8556323. |
fas antigen (cd95) is a cell surface protein that mediates apoptosis. |
1996-02-27 |
2023-08-12 |
human |
| H T Maecker, S Hedjbeli, M Alzona, P T L. Comparison of apoptosis signaling through T cell receptor, fas, and calcium ionophore. Experimental cell research. vol 222. issue 1. 1996-02-22. PMID:8549678. |
comparison of apoptosis signaling through t cell receptor, fas, and calcium ionophore. |
1996-02-22 |
2023-08-12 |
human |
| J L Shellhaas, S H Zuckerma. In vitro detection of apoptotic stimuli by use of the HL-60 myeloid leukemic cell line. Clinical and diagnostic laboratory immunology. vol 2. issue 5. 1996-02-21. PMID:8548540. |
in the present study, nondifferentiated hl-60 has served as a model for studying myeloid cell apoptosis by investigating apoptotic changes induced by camptothecin, a dna topoisomerase inhibitor, as well as physiologic stimuli, including ceramide analogs and a monoclonal antibody against the fas antigen. |
1996-02-21 |
2023-08-12 |
human |
| A Cerwenka, H Kovar, O Majdic, W Holte. Fas- and activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 2. 1996-02-14. PMID:8543794. |
the elimination of activated but not resting t cells involves apoptosis induced either by restimulation via the tcr/cd3 complex, cd2, or by signaling through the fas ag. |
1996-02-14 |
2023-08-12 |
human |
| H Ohashi, N Ogaw. [Analysis of Fas and bcl-2 expression on peripheral blood lymphocytes from primary Sjögren's syndrome]. Nihon rinsho. Japanese journal of clinical medicine. vol 53. issue 10. 1996-01-26. PMID:8531354. |
the fas antigen is the major trigger for apoptosis. |
1996-01-26 |
2023-08-12 |
mouse |
| H Ohashi, N Ogaw. [Analysis of Fas and bcl-2 expression on peripheral blood lymphocytes from primary Sjögren's syndrome]. Nihon rinsho. Japanese journal of clinical medicine. vol 53. issue 10. 1996-01-26. PMID:8531354. |
this study suggests that the increased expression of fas may result in enhanced susceptibility to apoptosis. |
1996-01-26 |
2023-08-12 |
mouse |
| A D Badley, J A McElhinny, P J Leibson, D H Lynch, M R Alderson, C V Pay. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. Journal of virology. vol 70. issue 1. 1996-01-25. PMID:8523526. |
upregulation of fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected t lymphocytes. |
1996-01-25 |
2023-08-12 |
human |