| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B A Osborn. Apoptosis and the maintenance of homoeostasis in the immune system. Current opinion in immunology. vol 8. issue 2. 1997-01-21. PMID:8725948. |
although the signal-transduction pathway leading from engagement of fas to apoptosis is not entirely clear, significant advances have been made recently. |
1997-01-21 |
2023-08-12 |
Not clear |
| T Brunner, N J Yoo, D LaFace, C F Ware, D R Gree. Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. International immunology. vol 8. issue 7. 1997-01-21. PMID:8757947. |
since the immunosuppressive drugs cyclosporin a (csa) and fk506 block activation-induced apoptosis in t cell hybridomas, we examined whether such compounds affect cell death by interfering with expression of fas, fasl or both, or whether they block fas signal transduction. |
1997-01-21 |
2023-08-12 |
Not clear |
| T Brunner, N J Yoo, D LaFace, C F Ware, D R Gree. Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. International immunology. vol 8. issue 7. 1997-01-21. PMID:8757947. |
furthermore, csa and fk506 do not interfere with fas signaling since anti-fas induced apoptosis in fas+ target cells was unaffected by these drugs. |
1997-01-21 |
2023-08-12 |
Not clear |
| T Brunner, N J Yoo, D LaFace, C F Ware, D R Gree. Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. International immunology. vol 8. issue 7. 1997-01-21. PMID:8757947. |
we therefore conclude that csa and fk506 block activation-induced apoptosis in t cell hybridomas predominantly by interfering with activation signals leading to fasl expression and, further, that the regulation of the expression of fas and fasl on activated t cells is differentially controlled. |
1997-01-21 |
2023-08-12 |
Not clear |
| A A Manfredi, P Rovere, S Heltai, M Ferrarin. Fas, apoptosis and the cell cycle. Immunology today. vol 17. issue 7. 1997-01-21. PMID:8763824. |
fas, apoptosis and the cell cycle. |
1997-01-21 |
2023-08-12 |
Not clear |
| Y R Chen, X Wang, D Templeton, R J Davis, T H Ta. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. The Journal of biological chemistry. vol 271. issue 50. 1997-01-17. PMID:8943238. |
direct correlation was found between jnk activation and apoptosis induced by uv-c and gamma radiation; however, jnk induction and apoptosis induced by fas signaling were not well correlated. |
1997-01-17 |
2023-08-12 |
Not clear |
| N Oguri-Hyakumachi, S Takahashi, T Nakagawa, K Kikuch. Selective depletion of cyclin-dependent kinases is associated with Fas-mediated apoptosis in human leukemia T-cell lines. International journal of immunopharmacology. vol 17. issue 11. 1997-01-16. PMID:8788121. |
the surface expression of fas antigen was unchanged in the variant cells, suggesting the requirement of the cytoplasmic mechanism to exert apoptosis. |
1997-01-16 |
2023-08-12 |
human |
| T Matsuyama, R Hata, Y Yamamoto, M Tagaya, H Akita, H Uno, A Wanaka, J Furuyama, M Sugit. Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization. Brain research. Molecular brain research. vol 34. issue 1. 1997-01-15. PMID:8750874. |
the expression of mrna for the fas antigen, a membrane-associated protein mediating apoptosis, was localized by in situ hybridization histochemistry in murine brains following 30 min of global cerebral ischemia. |
1997-01-15 |
2023-08-12 |
Not clear |
| M Iwamoto, T Koji, K Makiyama, N Kobayashi, P K Nakan. Apoptosis of crypt epithelial cells in ulcerative colitis. The Journal of pathology. vol 180. issue 2. 1997-01-13. PMID:8976873. |
the markers included dna breaks detected by tunel, fas (cd95/apo-1) and fas ligand (fas-l) localized by immunohistochemistry, electron microscopic features of apoptosis, and laddering of extracted dna. |
1997-01-13 |
2023-08-12 |
Not clear |
| P Vito, B Wolozin, J K Ganjei, K Iwasaki, E Lacanà, L D'Adami. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940094. |
alg-3, a truncated mouse homologue of the chromosome 1 familial alzheimer's disease gene ps2, rescues t hybridoma 3do cells from t-cell receptor-induced apoptosis by inhibiting fas ligand induction and fas signaling. |
1997-01-09 |
2023-08-12 |
mouse |
| D A Wright, B Futcher, P Ghosh, R S Geh. Association of human fas (CD95) with a ubiquitin-conjugating enzyme (UBC-FAP). The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940097. |
a single amino acid substitution in the death domain of fas that abolishes fas-mediated apoptosis also abolished fas association with ubc-fap, suggesting that ubc-fap may play a role in fas signal transduction. |
1997-01-09 |
2023-08-12 |
human |
| R A Freiberg, D M Spencer, K A Choate, P D Peng, S L Schreiber, G R Crabtree, P A Khavar. Specific triggering of the Fas signal transduction pathway in normal human keratinocytes. The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940187. |
the membrane receptor, fas, initiates apoptosis in many cell types, including keratinocytes. |
1997-01-09 |
2023-08-12 |
human |
| R A Freiberg, D M Spencer, K A Choate, P D Peng, S L Schreiber, G R Crabtree, P A Khavar. Specific triggering of the Fas signal transduction pathway in normal human keratinocytes. The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940187. |
oligomerization of fas, either with engineered fas.fkbp by fk1012 or via antibody cross-linking of full-length fas-induced cellular changes consistent with apoptosis. |
1997-01-09 |
2023-08-12 |
human |
| A G Eliopoulos, C W Dawson, G Mosialos, J E Floettmann, M Rowe, R J Armitage, J Dawson, J M Zapata, D J Kerr, M J Wakelam, J C Reed, E Kieff, L S Youn. CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator. Oncogene. vol 13. issue 10. 1997-01-09. PMID:8950992. |
we observed that contrary to the studies in normal b cells, cd40 ligation in carcinoma cell lines and in normal primary epithelial cells resulted in growth inhibition and enhanced susceptibility to apoptosis induced by anti-neoplastic drugs, tnf-alpha, fas and ceramide. |
1997-01-09 |
2023-08-12 |
Not clear |
| N Rouquet, K Carlier, P Briand, J Wiels, V Jouli. Multiple pathways of Fas-induced apoptosis in primary culture of hepatocytes. Biochemical and biophysical research communications. vol 229. issue 1. 1997-01-09. PMID:8954079. |
fas (apo1/cd95) is a member of the tumour necrosis factor/nerve growth factor receptor superfamily and mediates apoptosis in various cell types (for review sec [1]). |
1997-01-09 |
2023-08-12 |
Not clear |
| N Rouquet, K Carlier, P Briand, J Wiels, V Jouli. Multiple pathways of Fas-induced apoptosis in primary culture of hepatocytes. Biochemical and biophysical research communications. vol 229. issue 1. 1997-01-09. PMID:8954079. |
we and others previously showed that fas-induced apoptosis of primary culture hepatocytes requires either an inhibitor of translation or a protein kinase inhibitor, suggesting that two distinct pathways of fas signaling exist in hepatocytes. |
1997-01-09 |
2023-08-12 |
Not clear |
| B Huang, M Eberstadt, E T Olejniczak, R P Meadows, S W Fesi. NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain. Nature. vol 384. issue 6610. 1997-01-09. PMID:8967952. |
programmed cell death (apoptosis) mediated by the cytokine receptor fas is critical for the removal of autoreactive t cells, the mechanism of immune privilege, and for maintenance of immune-system homeostasis. |
1997-01-09 |
2023-08-12 |
Not clear |
| P D Katsikis, M E García-Ojeda, E S Wunderlich, C A Smith, H Yagita, K Okumura, N Kayagaki, M Alderson, L A Herzenberg, L A Herzenber. Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-infected individuals. International immunology. vol 8. issue 8. 1997-01-08. PMID:8918700. |
activation-induced peripheral blood t cell apoptosis is fas independent in hiv-infected individuals. |
1997-01-08 |
2023-08-12 |
Not clear |
| P D Katsikis, M E García-Ojeda, E S Wunderlich, C A Smith, H Yagita, K Okumura, N Kayagaki, M Alderson, L A Herzenberg, L A Herzenber. Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-infected individuals. International immunology. vol 8. issue 8. 1997-01-08. PMID:8918700. |
we recently showed that peripheral blood t cells from hiv-infected individuals are especially susceptible to fas antigen-induced apoptosis. |
1997-01-08 |
2023-08-12 |
Not clear |
| P D Katsikis, M E García-Ojeda, E S Wunderlich, C A Smith, H Yagita, K Okumura, N Kayagaki, M Alderson, L A Herzenberg, L A Herzenber. Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-infected individuals. International immunology. vol 8. issue 8. 1997-01-08. PMID:8918700. |
in this study we examine the role of fas, ctla-4, tumor necrosis factor (tnf) receptors (tnfr) and cd30, receptors known to be involved in t cell activation-induced cell death (aicd), in the spontaneous and activation (anti-cd3)-induced apoptosis of peripheral blood t cells from asymptomatic hiv-infected individuals. |
1997-01-08 |
2023-08-12 |
Not clear |