| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Rivoltini, M Radrizzani, P Accornero, P Squarcina, C Chiodoni, A Mazzocchi, C Castelli, P Tarsini, V Viggiano, F Belli, M P Colombo, G Parmian. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 3. 1998-08-12. PMID:9686582. |
human melanoma-reactive cd4+ and cd8+ ctl clones resist fas ligand-induced apoptosis and use fas/fas ligand-independent mechanisms for tumor killing. |
1998-08-12 |
2023-08-12 |
human |
| L Rivoltini, M Radrizzani, P Accornero, P Squarcina, C Chiodoni, A Mazzocchi, C Castelli, P Tarsini, V Viggiano, F Belli, M P Colombo, G Parmian. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 3. 1998-08-12. PMID:9686582. |
tumor cells have been shown recently to escape immune recognition by developing resistance to fas-mediated apoptosis and acquiring expression of fas ligand (fasl) molecule that they may use for eliminating activated fas+ lymphocytes. |
1998-08-12 |
2023-08-12 |
human |
| L Rivoltini, M Radrizzani, P Accornero, P Squarcina, C Chiodoni, A Mazzocchi, C Castelli, P Tarsini, V Viggiano, F Belli, M P Colombo, G Parmian. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 3. 1998-08-12. PMID:9686582. |
melanoma cells (and normal melanocytes) express heterogeneous levels of fas molecule, but they result homogeneously resistant to fas-induced apoptosis. |
1998-08-12 |
2023-08-12 |
human |
| M Sakurai, T Hayashi, K Abe, M Sadahiro, K Tabayash. Delayed selective motor neuron death and fas antigen induction after spinal cord ischemia in rabbits. Brain research. vol 797. issue 1. 1998-08-06. PMID:9630489. |
the expression of fas antigen may be related to the activation of apoptosis signal in motor neuron cells after spinal cord ischemia in rabbits. |
1998-08-06 |
2023-08-12 |
rabbit |
| C Y Chen, J Liou, L W Forman, D V Falle. Differential regulation of discrete apoptotic pathways by Ras. The Journal of biological chemistry. vol 273. issue 27. 1998-08-06. PMID:9642224. |
engagement of fas antigen, a potent effector of apoptosis, activates cellular p21(ras), which may be required for completion of the cell death program. |
1998-08-06 |
2023-08-12 |
mouse |
| C Y Chen, J Liou, L W Forman, D V Falle. Differential regulation of discrete apoptotic pathways by Ras. The Journal of biological chemistry. vol 273. issue 27. 1998-08-06. PMID:9642224. |
in contrast, fas engagement, although inducing a vigorous and pkc-independent activation of endogenous p21(ras), did not alter cell cycle progression, nor did it require such progression for apoptosis. |
1998-08-06 |
2023-08-12 |
mouse |
| H U Simon, S Yousefi, B Dibbert, H Hebestreit, M Weber, D R Branch, K Blaser, F Levi-Schaffer, G P Anderso. Role for tyrosine phosphorylation and Lyn tyrosine kinase in fas receptor-mediated apoptosis in eosinophils. Blood. vol 92. issue 2. 1998-08-06. PMID:9657755. |
role for tyrosine phosphorylation and lyn tyrosine kinase in fas receptor-mediated apoptosis in eosinophils. |
1998-08-06 |
2023-08-12 |
mouse |
| H U Simon, S Yousefi, B Dibbert, H Hebestreit, M Weber, D R Branch, K Blaser, F Levi-Schaffer, G P Anderso. Role for tyrosine phosphorylation and Lyn tyrosine kinase in fas receptor-mediated apoptosis in eosinophils. Blood. vol 92. issue 2. 1998-08-06. PMID:9657755. |
fas ligand/fas receptor molecular interactions have been implicated as having an important function for the regulation of eosinophil apoptosis. |
1998-08-06 |
2023-08-12 |
mouse |
| L Xerri, R Bouabdallah, E Devilard, J Hassoun, A M Stoppa, F Bir. Sensitivity to Fas-mediated apoptosis is null or weak in B-cell non-Hodgkin's lymphomas and is moderately increased by CD40 ligation. British journal of cancer. vol 78. issue 2. 1998-08-06. PMID:9683298. |
the fas receptor (apo-1/cd95) is capable of inducing apoptosis of lymphoid cells and is expressed in some non-hodgkin's lymphomas (nhls). |
1998-08-06 |
2023-08-12 |
Not clear |
| L Xerri, R Bouabdallah, E Devilard, J Hassoun, A M Stoppa, F Bir. Sensitivity to Fas-mediated apoptosis is null or weak in B-cell non-Hodgkin's lymphomas and is moderately increased by CD40 ligation. British journal of cancer. vol 78. issue 2. 1998-08-06. PMID:9683298. |
the sensitivity of lymphoma cells to fas-mediated apoptosis was correlated neither with the histological subtypes nor with the level of fas expression. |
1998-08-06 |
2023-08-12 |
Not clear |
| L Xerri, R Bouabdallah, E Devilard, J Hassoun, A M Stoppa, F Bir. Sensitivity to Fas-mediated apoptosis is null or weak in B-cell non-Hodgkin's lymphomas and is moderately increased by CD40 ligation. British journal of cancer. vol 78. issue 2. 1998-08-06. PMID:9683298. |
activation of neoplastic b cells by cd40 ligation resulted in significant increases in fas expression and fas-induced apoptosis among the five b-nhl cases tested. |
1998-08-06 |
2023-08-12 |
Not clear |
| Y W Zhou, Y Komada, H Inaba, E Azuma, M Sakura. Down-regulation of Fas-associated phosphatase-1 (FAP-1) in interleukin-2-activated T cells. Cellular immunology. vol 186. issue 2. 1998-08-05. PMID:9665752. |
peripheral t cells are resistant to fas receptor (fasr/cd95)-mediated apoptosis. |
1998-08-05 |
2023-08-12 |
Not clear |
| S Spiegel, O Cuvillier, L C Edsall, T Kohama, R Menzeleev, Z Olah, A Olivera, G Pirianov, D M Thomas, Z Tu, J R Van Brocklyn, F Wan. Sphingosine-1-phosphate in cell growth and cell death. Annals of the New York Academy of Sciences. vol 845. 1998-08-04. PMID:9668339. |
while ceramide has been shown to be an important regulatory component of apoptosis induced by tumor necrosis factor alpha and fas ligand, sphingosine-1-phosphate (spp), a further metabolite of ceramide, has been implicated as a second messenger in cellular proliferation and survival induced by platelet-derived growth factor, nerve growth factor, and serum. |
1998-08-04 |
2023-08-12 |
Not clear |
| S Nemoto, J Xiang, S Huang, A Li. Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. The Journal of biological chemistry. vol 273. issue 26. 1998-08-03. PMID:9632706. |
in addition, sb202190 was able to potentiate apoptosis induced by fas(apo-1) ligation or uv irradiation. |
1998-08-03 |
2023-08-12 |
Not clear |
| K K Lee, M Murakawa, E Nishida, S Tsubuki, S Kawashima, K Sakamaki, S Yonehar. Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis. Oncogene. vol 16. issue 23. 1998-08-03. PMID:9662336. |
the fas system has been extensively investigated as a model of apoptosis and the caspase cascade has been shown to be a characteristic mechanism of signaling of apoptosis. |
1998-08-03 |
2023-08-12 |
human |
| A J McGahon, A P Costa Pereira, L Daly, T G Cotte. Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system. British journal of haematology. vol 101. issue 3. 1998-07-31. PMID:9633899. |
chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the fas (apo-1/cd95) receptor/ligand system. |
1998-07-31 |
2023-08-12 |
human |
| A J McGahon, A P Costa Pereira, L Daly, T G Cotte. Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system. British journal of haematology. vol 101. issue 3. 1998-07-31. PMID:9633899. |
the potential role of the fas (cd95/apo-1) receptor/ligand system in chemotherapeutic drug-induced apoptosis was examined in a number of human leukaemic cell lines. |
1998-07-31 |
2023-08-12 |
human |
| A J McGahon, A P Costa Pereira, L Daly, T G Cotte. Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system. British journal of haematology. vol 101. issue 3. 1998-07-31. PMID:9633899. |
flow cytometric profiles of doxorubicin-treated hl-60, k562, u937 and jurkat cells failed to show any significant increase in fas or fas ligand expression over 24 h, despite the induction of significant levels of apoptosis in these cells. |
1998-07-31 |
2023-08-12 |
human |
| J P Weintraub, V Godfrey, P A Wolthusen, R L Cheek, R A Eisenberg, P L Cohe. Immunological and pathological consequences of mutations in both Fas and Fas ligand. Cellular immunology. vol 186. issue 1. 1998-07-30. PMID:9637760. |
to determine if fas expressed in lpr mice is contributing to apoptosis we generated a novel strain of mice (b6/lprgld) which is homozygous for both the lpr mutation and the gld mutation which encodes nonfunctional fas ligand (fasl) protein. |
1998-07-30 |
2023-08-12 |
mouse |
| J P Weintraub, V Godfrey, P A Wolthusen, R L Cheek, R A Eisenberg, P L Cohe. Immunological and pathological consequences of mutations in both Fas and Fas ligand. Cellular immunology. vol 186. issue 1. 1998-07-30. PMID:9637760. |
if low levels of fas in b6/lpr mice contribute to apoptosis and lessen the severity of disease, the b6/lprgld mice, which also lack functional fasl, would be expected to develop a more severe form of disease than b6/lpr mice. |
1998-07-30 |
2023-08-12 |
mouse |