| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R G Fenton, J A Hixon, P W Wright, A D Brooks, T J Sayer. Inhibition of Fas (CD95) expression and Fas-mediated apoptosis by oncogenic Ras. Cancer research. vol 58. issue 15. 1998-08-27. PMID:9699671. |
these data indicate that oncogenic ras inhibits basal levels of expression of the fas gene, and although cytokine signal transduction pathways are functional in these cells, the level of surface fas expression remains below the threshold required for induction of apoptosis. |
1998-08-27 |
2023-08-12 |
Not clear |
| M X Wu, Z Ao, K V Prasad, R Wu, S F Schlossma. IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science (New York, N.Y.). vol 281. issue 5379. 1998-08-25. PMID:9703517. |
one such gene that protects cells from apoptosis induced by fas or tumor necrosis factor type alpha (tnf), iex-1l, is described here. |
1998-08-25 |
2023-08-12 |
Not clear |
| L S Walker, J D McLeod, G Boulougouris, Y I Patel, N D Hall, D M Sanso. Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis. Immunology. vol 94. issue 1. 1998-08-24. PMID:9708185. |
down-regulation of cd28 via fas (cd95): influence of cd28 on t-cell apoptosis. |
1998-08-24 |
2023-08-12 |
human |
| L S Walker, J D McLeod, G Boulougouris, Y I Patel, N D Hall, D M Sanso. Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis. Immunology. vol 94. issue 1. 1998-08-24. PMID:9708185. |
whilst cd28-mediated signalling is increasingly associated with survival, ligation of alternative t-cell antigens, such as fas (cd95), can trigger apoptosis. |
1998-08-24 |
2023-08-12 |
human |
| A Deptala, H D Halicka, B Ardelt, W Ardelt, S M Mikulski, K Shogen, Z Darzynkiewic. Potentiation of tumor necrosis factor induced apoptosis by onconase. International journal of oncology. vol 13. issue 1. 1998-08-20. PMID:9625797. |
indeed, preincubation of u-937 or hl-60 leukemic cells with 0.17 microm onc rendered them more sensitive to induction of apoptosis by tnf-alpha or antibody to cd95 (fas). |
1998-08-20 |
2023-08-12 |
mouse |
| L Genestier, R Paillot, S Fournel, C Ferraro, P Miossec, J P Revillar. Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. The Journal of clinical investigation. vol 102. issue 2. 1998-08-20. PMID:9664073. |
apoptosis of activated t cells did not require interaction between cd95 (fas, apo-1) and its ligand, and adenosine release accounted for only a small part of this mtx activity. |
1998-08-20 |
2023-08-12 |
human |
| R Halenbeck, H MacDonald, A Roulston, T T Chen, L Conroy, L T William. CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45. Current biology : CB. vol 8. issue 9. 1998-08-18. PMID:9560346. |
induction of apoptosis by death receptors such as fas or tumour necrosis factor (tnf) r1 leads to distinct changes in cell morphology, activation of the caspase protease cascade, and the degradation of nuclear chromatin by activated nucleases. |
1998-08-18 |
2023-08-12 |
mouse |
| T Yagi, A Sugimoto, M Tanaka, S Nagata, S Yasuda, H Yagita, T Kuriyama, T Takemori, Y Tsunetsugu-Yokot. Fas/FasL interaction is not involved in apoptosis of activated CD4+ T cells upon HIV-1 infection in vitro. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. vol 18. issue 4. 1998-08-18. PMID:9704935. |
in hiv-1-infected individuals, fas expression and fas/fasl-mediated apoptosis of mature t cells are known to increase compared with those in normal individuals. |
1998-08-18 |
2023-08-12 |
Not clear |
| H C Hsu, X Su, J D Mount. Increased susceptibility to apoptosis induced by anti-Fas antibody in a Rothmund-Thomson syndrome lymphoblastoid cell line. Proceedings of the Association of American Physicians. vol 110. issue 3. 1998-08-17. PMID:9625528. |
taken together, these results provide the first evidence to show that rts lymphoblastoid has an increased sensitivity to cell death mediated by fas and that inhibition of caspase-3 activity may be a potential target in reversing the sensitivity of rts cells to fas-mediated apoptosis in vitro. |
1998-08-17 |
2023-08-12 |
human |
| J R Schelling, N Nkemere, J B Kopp, R P Clevelan. Fas-dependent fratricidal apoptosis is a mechanism of tubular epithelial cell deletion in chronic renal failure. Laboratory investigation; a journal of technical methods and pathology. vol 78. issue 7. 1998-08-17. PMID:9690559. |
because the fas apoptosis pathway has recently been implicated in disease pathogenesis and fas is expressed in the kidney, we hypothesized that fas-mediated apoptosis of renal tubule epithelial cells (rtc) contributes to tubular atrophy in chronic renal failure. |
1998-08-17 |
2023-08-12 |
Not clear |
| J R Schelling, N Nkemere, J B Kopp, R P Clevelan. Fas-dependent fratricidal apoptosis is a mechanism of tubular epithelial cell deletion in chronic renal failure. Laboratory investigation; a journal of technical methods and pathology. vol 78. issue 7. 1998-08-17. PMID:9690559. |
in vivo, immunohistochemical analyses of renal sections from two murine models of progressive renal disease revealed coordinate increases in rtc fas expression and apoptosis compared with tissue sections from age-matched control kidneys. |
1998-08-17 |
2023-08-12 |
Not clear |
| J R Schelling, N Nkemere, J B Kopp, R P Clevelan. Fas-dependent fratricidal apoptosis is a mechanism of tubular epithelial cell deletion in chronic renal failure. Laboratory investigation; a journal of technical methods and pathology. vol 78. issue 7. 1998-08-17. PMID:9690559. |
functional studies revealed that interleukin-1alpha-stimulated rtc fas expression was accompanied by increased apoptosis, which was inhibited by blocking anti-fas ligand antibodies. |
1998-08-17 |
2023-08-12 |
Not clear |
| J R Schelling, N Nkemere, J B Kopp, R P Clevelan. Fas-dependent fratricidal apoptosis is a mechanism of tubular epithelial cell deletion in chronic renal failure. Laboratory investigation; a journal of technical methods and pathology. vol 78. issue 7. 1998-08-17. PMID:9690559. |
in contrast to the conventional paradigm, which holds that fas-dependent apoptosis is initiated by the binding of lymphocyte fas ligand to target cell fas, our data suggest that up-regulated rtc fas binds to fas ligand on adjacent rtc, which then leads to rtc death by fratricide. |
1998-08-17 |
2023-08-12 |
Not clear |
| K Frei, B Ambar, N Adachi, Y Yonekawa, A Fontan. Ex vivo malignant glioma cells are sensitive to Fas (CD95/APO-1) ligand-mediated apoptosis. Journal of neuroimmunology. vol 87. issue 1-2. 1998-08-13. PMID:9670851. |
ex vivo malignant glioma cells are sensitive to fas (cd95/apo-1) ligand-mediated apoptosis. |
1998-08-13 |
2023-08-12 |
human |
| K Frei, B Ambar, N Adachi, Y Yonekawa, A Fontan. Ex vivo malignant glioma cells are sensitive to Fas (CD95/APO-1) ligand-mediated apoptosis. Journal of neuroimmunology. vol 87. issue 1-2. 1998-08-13. PMID:9670851. |
fas (also known as cd95/apo-1) is a cell surface receptor and member of the tumor necrosis factor receptor superfamily which mediates apoptosis in sensitive cells upon oligomerization by specific antibodies or by its ligand (fasl). |
1998-08-13 |
2023-08-12 |
human |
| Y Mizutani, O Yoshida, B Bonavid. Sensitization of human bladder cancer cells to Fas-mediated cytotoxicity by cis-diamminedichloroplatinum (II). The Journal of urology. vol 160. issue 2. 1998-08-13. PMID:9679929. |
like the fas ligand, anti-fas monoclonal antibody (mab) induces apoptosis in tumor cells expressing fas. |
1998-08-13 |
2023-08-12 |
human |
| Y Mizutani, O Yoshida, B Bonavid. Sensitization of human bladder cancer cells to Fas-mediated cytotoxicity by cis-diamminedichloroplatinum (II). The Journal of urology. vol 160. issue 2. 1998-08-13. PMID:9679929. |
several anticancer drugs also mediate apoptosis and may share with fas common intracellular pathways leading to cell killing. |
1998-08-13 |
2023-08-12 |
human |
| M Tamura, H Kimura, T Koji, T Tominaga, K Ashizawa, T Kiriyama, N Yokoyama, T Yoshimura, K Eguchi, P K Nakane, S Nagatak. Role of apoptosis of thyrocytes in a rat model of goiter. A possible involvement of Fas system. Endocrinology. vol 139. issue 8. 1998-08-13. PMID:9681519. |
we also investigated the association between fas and fasl expression and thyrocyte apoptosis using immunohistochemistry and western blotting. |
1998-08-13 |
2023-08-12 |
rat |
| W Luttmann, A Opfer, E Dauer, M Foerster, H Matthys, H Eibel, K Schulze-Osthoff, C Kroegel, J C Vircho. Differential regulation of CD95 (Fas/APO-1) expression in human blood eosinophils. European journal of immunology. vol 28. issue 7. 1998-08-13. PMID:9692873. |
cd95 (fas, apo-1) is a cell surface receptor expressed on many cells including eosinophils which mediates apoptosis when ligated by agonistic antibodies or its natural ligand fasl. |
1998-08-13 |
2023-08-12 |
human |
| P Krajcsi, W S Wol. Inhibition of tumor necrosis factor and interferon triggered responses by DNA viruses. Seminars in cell & developmental biology. vol 9. issue 3. 1998-08-12. PMID:9665872. |
depending on the dna virus and the viral proteins, the following mechanisms to prevent tnf receptor- and fas-induced apoptosis are used: (1) absorption of extracellular tnf by secreted homologs of the tnf receptor; (2) degradation of fas; (3) inhibition of the assembly of fadd and caspase 8 with tnfr1 and fas; (4) direct inhibition of proapoptotic caspase enzymatic activity; and (5) inhibition of the proapoptotic members of the bcl-2 family. |
1998-08-12 |
2023-08-12 |
Not clear |