| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Noboru Uchide, Kunio Ohyama, Bo Yuan, Tomomi Sano, Toshio Bessho, Toshio Yamakaw. Differential mRNA expression of inflammatory cytokines in cultured human fetal membrane cells responding to influenza virus infection. Biological & pharmaceutical bulletin. vol 25. issue 2. 2002-08-02. PMID:11853174. |
moreover, tnf-alpha, ifn-beta, ifn-gamma and fas do not appear to be directly involved in the apoptosis induction of iv-infected chorion cells. |
2002-08-02 |
2023-08-12 |
human |
| Olivier Dereure, Edi Levi, Eric C Vonderheid, Marshall E Kadi. Infrequent Fas mutations but no Bax or p53 mutations in early mycosis fungoides: a possible mechanism for the accumulation of malignant T lymphocytes in the skin. The Journal of investigative dermatology. vol 118. issue 6. 2002-08-02. PMID:12060388. |
in this study, we investigate possible alterations of three molecules regulating apoptosis, i.e., fas antigen, bax, and p53, at the genomic level in skin lesions from 44 patients with mf, as fas mediates one of two major pathways for apoptosis of activated t cells. |
2002-08-02 |
2023-08-12 |
Not clear |
| Kathrin Maedler, Adriano Fontana, Frédéric Ris, Pavel Sergeev, Christian Toso, José Oberholzer, Roger Lehmann, Felix Bachmann, Andrea Tasinato, Giatgen A Spinas, Philippe A Halban, Marc Y Donat. FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 12. 2002-08-02. PMID:12060768. |
in human islets, elevated glucose concentrations impair beta cell proliferation and induce beta cell apoptosis via up-regulation of the fas receptor. |
2002-08-02 |
2023-08-12 |
human |
| Kathrin Maedler, Adriano Fontana, Frédéric Ris, Pavel Sergeev, Christian Toso, José Oberholzer, Roger Lehmann, Felix Bachmann, Andrea Tasinato, Giatgen A Spinas, Philippe A Halban, Marc Y Donat. FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 12. 2002-08-02. PMID:12060768. |
the present data provide evidence for expression of flip in the human beta cell and suggest a novel approach to prevent and treat diabetes by switching fas signaling from apoptosis to proliferation. |
2002-08-02 |
2023-08-12 |
human |
| Gal Yaniv, Mark Shilkrut, Rona Lotan, Gideon Berke, Sarit Larisch, Ofer Bina. Hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the Fas (CD95/Apo-1) receptor: Fas activation and apoptosis in hypoxic myocytes. Cardiovascular research. vol 54. issue 3. 2002-08-01. PMID:12031707. |
hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the fas (cd95/apo-1) receptor: fas activation and apoptosis in hypoxic myocytes. |
2002-08-01 |
2023-08-12 |
rat |
| P Legembre, P Moreau, S Daburon, J-F Moreau, J-L Taupi. Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas. Cell death and differentiation. vol 9. issue 3. 2002-07-31. PMID:11859415. |
potentiation of fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked fas. |
2002-07-31 |
2023-08-12 |
Not clear |
| P Legembre, P Moreau, S Daburon, J-F Moreau, J-L Taupi. Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas. Cell death and differentiation. vol 9. issue 3. 2002-07-31. PMID:11859415. |
surprisingly, despite lacking the death domain region of functional fas, fas-gpi was able to significantly increase fas-mediated cell death triggered by membrane bound or soluble fasl, whereas engagement of fas-gpi alone did not trigger apoptosis. |
2002-07-31 |
2023-08-12 |
Not clear |
| Y E Claessens, M Fontenay-Roupi. [Physiopathology of myelodysplastic syndromes]. Pathologie-biologie. vol 50. issue 4. 2002-07-31. PMID:12085671. |
this growth defect could be linked to (1) a resistance to hematopoietic cytokine stimulation although, erythropoietin receptor expression and functionality are normal and/or (2) increased susceptibility to apoptosis due to overexpression of the death domain receptor fas on cd34+, cd33+ and gpa+ cells. |
2002-07-31 |
2023-08-12 |
Not clear |
| S de Jong, T Timmer, F J Heijenbrok, E G de Vrie. Death receptor ligands, in particular TRAIL, to overcome drug resistance. Cancer metastasis reviews. vol 20. issue 1-2. 2002-07-30. PMID:11831647. |
the death receptor ligands tumor necrosis factor (tnf), fas ligand (fasl) and tnf-related apoptosis-inducing ligand (trail) are able to induce apoptosis by binding to their cell membrane receptors. |
2002-07-30 |
2023-08-12 |
Not clear |
| Hans U Schmelz, Michael Abend, Klaus Kraft, Ekkehard W Hauck, Wolfgang Weidner, Dirk Van Beuningen, Christoph Sparwasse. Fas/Fas ligand system and apoptosis induction in testicular carcinoma. Cancer. vol 95. issue 1. 2002-07-30. PMID:12115319. |
tumor-infiltrating, fas ligand (fasl)-expressing lymphocytes are able to eliminate fas-bearing tumor cells by apoptosis induction. |
2002-07-30 |
2023-08-12 |
Not clear |
| Hans U Schmelz, Michael Abend, Klaus Kraft, Ekkehard W Hauck, Wolfgang Weidner, Dirk Van Beuningen, Christoph Sparwasse. Fas/Fas ligand system and apoptosis induction in testicular carcinoma. Cancer. vol 95. issue 1. 2002-07-30. PMID:12115319. |
activated cytotoxic t-cells that express fas may enter apoptosis in the presence of fasl tumor cells. |
2002-07-30 |
2023-08-12 |
Not clear |
| Michele M Kosiewicz, Anasuya Krishnan, Mark T Worthington, James A Matriano, William G Ros. B cells engineered to express Fas ligand suppress pre-sensitized antigen-specific T cell responses in vivo. European journal of immunology. vol 32. issue 6. 2002-07-30. PMID:12115651. |
inducing apoptosis of activated lymphocytes via fas ligand (fasl, cd95) may be a useful strategy for the treatment of autoimmune diseases mediated by pathogenic t cells. |
2002-07-30 |
2023-08-12 |
Not clear |
| Shuichiro Ito, Tomoko Takayama, Hiroyuki Hanzawa, Kimihisa Ichikawa, Jun Ohsumi, Nobufusa Serizawa, Tadashi Hata, Hideyuki Haruyam. Crystal structure of the antigen-binding fragment of apoptosis-inducing mouse anti-human Fas monoclonal antibody HFE7A. Journal of biochemistry. vol 131. issue 1. 2002-07-26. PMID:11754745. |
binding of fas ligand to fas induces apoptosis. |
2002-07-26 |
2023-08-12 |
mouse |
| Shuichiro Ito, Tomoko Takayama, Hiroyuki Hanzawa, Kimihisa Ichikawa, Jun Ohsumi, Nobufusa Serizawa, Tadashi Hata, Hideyuki Haruyam. Crystal structure of the antigen-binding fragment of apoptosis-inducing mouse anti-human Fas monoclonal antibody HFE7A. Journal of biochemistry. vol 131. issue 1. 2002-07-26. PMID:11754745. |
the mouse anti-human fas monoclonal antibody hfe7a (m-hfe7a), which induces apoptosis, has been humanized based on a structure predicted by homology modeling. |
2002-07-26 |
2023-08-12 |
mouse |
| P S Wang, Y M Chen, Y L Hsieh, C F Yu, C M Tsai, R P Pern. Pleural effusion and serum soluble fas-ligand levels are elevated in different clinical conditions. Lung. vol 180. issue 1. 2002-07-26. PMID:12105754. |
fas ligand (fasl) plays an important role in the regulation of apoptosis. |
2002-07-26 |
2023-08-12 |
Not clear |
| T Tsuda, Y Ohmori, H Muramatsu, Y Hosaka, K Takiguchi, F Saitoh, K Kato, K Nakayama, N Nakamura, S Nagata, H Mochizuk. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia. European journal of pharmacology. vol 433. issue 1. 2002-07-25. PMID:11755132. |
m50054, 2,2'-methylenebis (1,3-cyclohexanedione), was identified as a novel inhibitor of apoptosis (programmed cell death) using an in vitro cell death assay system induced in human fas-expressing wc8 cells by soluble human fas ligand. |
2002-07-25 |
2023-08-12 |
human |
| Christelle Lamboley, Annie-France Bringuier, Emmanuel Camus, Bernard Lardeux, André Groyer, Gérard Feldman. Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis. Journal of hepatology. vol 36. issue 3. 2002-07-25. PMID:11867183. |
overexpression of the mouse fas gene in human hep3b hepatoma cells overcomes their resistance to fas-mediated apoptosis. |
2002-07-25 |
2023-08-12 |
mouse |
| Wenli Wang, Chengyu Z Prince, Yongshan Mou, Matthew J Pollma. Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation. Resistance to Fas ligand-induced apoptosis. The Journal of biological chemistry. vol 277. issue 24. 2002-07-25. PMID:11925448. |
resistance to fas ligand-induced apoptosis. |
2002-07-25 |
2023-08-12 |
Not clear |
| Yoshiya Tanaka, Shingo Nakayamada, Hiroko Fujimoto, Yosuke Okada, Hisanori Umehara, Tohru Kataoka, Yasuhiro Minam. H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts. The Journal of biological chemistry. vol 277. issue 24. 2002-07-25. PMID:11934900. |
thus, we propose that h-ras signals followed by raf-1/mapk pathway but not pi3k not only reduces beta(1)-mediated adhesion of osteoblasts to matrix proteins but induces apoptosis presumably via the fas up-regulation and bcl-2 down-regulation. |
2002-07-25 |
2023-08-12 |
human |
| P O Fritsch, A Sidorof. Drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. American journal of clinical dermatology. vol 1. issue 6. 2002-07-24. PMID:11702611. |
recently, in a small series of patients, intravenous immunoglobulins were presumed to be effective by the blockade of lytic fas ligand-mediated apoptosis in sjs/ten. |
2002-07-24 |
2023-08-12 |
Not clear |