| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wioleta Justyna Omeljaniuk, Marzena Garley, Anna Pryczynicz, Joanna Motyka, Angelika Edyta Charkiewicz, Elżbieta Milewska, Piotr Laudański, Wojciech Milty. NLRP3 Inflammasome in the Pathogenesis of Miscarriages. International journal of molecular sciences. vol 25. issue 19. 2024-10-16. PMID:39408839. |
in the placental tissue, the expression of nlrp3, il-1β, il-18, and caspase-1 as well as that of the classical apoptosis biomarkers fas, fasl, bcl-2, and ca was evaluated by means of immunohistochemistry techniques. |
2024-10-16 |
2024-10-18 |
Not clear |
| Yuan-Yuan Liu, Ning Li, Xing-Yuan Chen, Hui Wang, Shao-Wei Zhu, Lan Yang, Fang-Yi Quan, Jian-Chun Ma, Jian-Wei Dai, Ya-le Jiang, Zhou-Fu Xiang, Qi Cheng, Wei-Hao Zhang, Ke-Han Chen, Wei Hou, Hai-Rong Xion. MicroRNA let-7a regulation of Hantaan virus replication by Targeting FAS Signaling Pathways. Virology. vol 600. 2024-10-09. PMID:39383773. |
mirna let-7a mimics and inhibitors validated the predicted targets, including cell apoptosis genes (fas, caspase-8, and caspase-3) and inflammatory factors (il-6 and its related factors). |
2024-10-09 |
2024-10-12 |
human |
| Malgorzata Krzyzowska, Magdalena Patrycy, Marcin Chodkowski, Martyna Janicka, Andrzej Kowalczyk, Katarzyna Skulska, Karolina Thörn, Kristina Eriksso. Fas/FasL-Mediated Apoptosis and Inflammation Contribute to Recovery from HSV-2-Mediated Spinal Cord Infection. Viruses. vol 16. issue 9. 2024-09-28. PMID:39339840. |
in vitro, we confirmed that fas and fasl is required for the induction of leucocyte apoptosis, but also show that the fas/fasl pathway is required for adequate cytokine and chemokine production by glial cells. |
2024-09-28 |
2024-10-01 |
mouse |
| Zahra Tahmasebi Far. Evaluation of the Effect of Menopausal Status and BMI on Polymorphisms in Fas/Fas L and the Risk of Breast Cancer. Clinical breast cancer. 2024-08-30. PMID:39214844. |
fas and fas ligand play an essential role in cell apoptosis. |
2024-08-30 |
2024-09-04 |
Not clear |
| Xing Wu, Yixiang Tian, Na Zhang, Yangguang Ren, Zihao Zhang, Yudian Zhao, Yulong Guo, Yujie Gong, Yanhua Zhang, Donghua Li, Hong Li, Ruirui Jiang, Guoxi Li, Xiaojun Liu, Xiangtao Kang, Yadong Tia. The role of AdipoQ on proliferation, apoptosis, and hormone Secretion in chicken primary adenohypophysis cells. Poultry science. vol 103. issue 10. 2024-08-14. PMID:39142032. |
furthermore, adipoq inhibited apoptosis of chicken primary adenohypophysis cells, resulting in down-regulation of pro-apoptotic genes caspase3, fas, and fasl mrna expression, and decreased caspase3 protein expression (p < 0.05). |
2024-08-14 |
2024-08-17 |
chicken |
| Jabeen Farheen, M Zubair Iqbal, Asim Mushtaq, Yike Hou, Xiangdong Kon. Hippophae Rhamnoides-derived Phytomedicine Nano-System Modulates Bax/Fas Pathways to Reduce Proliferation in Triple-Negative Breast Cancer. Advanced healthcare materials. 2024-08-12. PMID:39132863. |
mechanistically, in vivo sbp-met proteome expression profiling reveals upregulation of proapoptotic bax protein and activation of fas signaling pathways convince downstream daxx and fadd proteins, which further triggers caspase-3 that prompts apoptosis in human tnbc cells by cleaving parp-1 protein. |
2024-08-12 |
2024-08-14 |
human |
| Zhengqun Liu, Han Wang, Hui Han, Ning Li, Zi Zheng, Shiyue Liang, Ruqing Zhong, Liang Chen, Jun Yan, Shuqin M. The protective effect of dulcitol on lipopolysaccharide-induced intestinal injury in piglets: mechanistic insights. The Journal of nutritional biochemistry. 2024-08-05. PMID:39103108. |
proteomics showed that dulcitol supplementation altered the protein expression involved in maintaining barrier integrity (fn1, cadm1, and pard3), inhibiting inflammatory response (slp1, sfn, and irf3), and apoptosis (including fas, ing1, btk, mthfr, nox, and p53bp2) in lps-challenged piglets (p <0.05). |
2024-08-05 |
2024-08-08 |
Not clear |
| Jingchao Wang, Daoyuan Huang, Thu Anh Thai Nguyen, Liem Minh Phan, Wenyi Wei, Abdol-Hossein Rezaeia. CD74-AKT Axis Is a Potential Therapeutic Target in Triple-Negative Breast Cancer. Biology. vol 13. issue 7. 2024-07-26. PMID:39056676. |
triple-negative breast cancer (tnbc) cells are often resistant to fas (cd95)-mediated apoptosis, but the underlying molecular mechanism(s) is not fully understood yet. |
2024-07-26 |
2024-07-28 |
Not clear |
| Jingchao Wang, Daoyuan Huang, Thu Anh Thai Nguyen, Liem Minh Phan, Wenyi Wei, Abdol-Hossein Rezaeia. CD74-AKT Axis Is a Potential Therapeutic Target in Triple-Negative Breast Cancer. Biology. vol 13. issue 7. 2024-07-26. PMID:39056676. |
we also revealed that cd74 binds to fas and interferes with the intrinsic signaling of fas-mediated apoptosis. |
2024-07-26 |
2024-07-28 |
Not clear |
| Ayman Hyder, Basma Sheta, Manar Eissa, Jürgen Schrezenmei. Silencing the FABP3 gene in insulin-secreting cells reduces fatty acid uptake and protects against lipotoxicity. Acta diabetologica. 2024-07-03. PMID:38960943. |
long-term exposure of pancreatic islets to fatty acids (fas), common in obesity, metabolic syndrome, and type 2 diabetes, leads to a compensatory hyperactivity followed by inflammation, apoptosis, dysfunctional beta cells, and results in insulin dependence of the patient. |
2024-07-03 |
2024-07-10 |
Not clear |
| Mehmet H Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T Chan, Valeria I Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R Sewanan, In-Hyun Park, Laura E Niklason, Comert Kura. Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis. Cell death & disease. vol 15. issue 6. 2024-06-22. PMID:38909035. |
although fas is highly expressed in cancer cells, insufficient cell surface fas expression desensitizes cancer cells to fas-induced apoptosis. |
2024-06-22 |
2024-06-25 |
mouse |
| Mehmet H Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T Chan, Valeria I Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R Sewanan, In-Hyun Park, Laura E Niklason, Comert Kura. Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis. Cell death & disease. vol 15. issue 6. 2024-06-22. PMID:38909035. |
here, we show that the increase in fas microaggregate formation on the plasma membrane in response to the inhibition of endocytosis sensitizes cancer cells to fas-induced apoptosis. |
2024-06-22 |
2024-06-25 |
mouse |
| Wei Jiang, Tao-Tao Tang, Yi-Lin Zhang, Zuo-Lin Li, Yi Wen, Qin Yang, Yu-Qi Fu, Jing Song, Qiu-Li Wu, Min Wu, Bin Wang, Bi-Cheng Liu, Lin-Li L. CD8 T cells induce the peritubular capillary rarefaction during AKI to CKD transition. International journal of biological sciences. vol 20. issue 8. 2024-06-21. PMID:38904017. |
notably, cd8 t cells induced endothelial cell apoptosis via fas ligand-fas signaling. |
2024-06-21 |
2024-06-23 |
mouse |
| Fei Wang, Shuheng Qin, Jiejie Zhang, Menglu Huang, Qin Liu, Peipei Xu, Yong H. Low-dose doxorubicin loaded extracellular vesicles combined Fas/FasL pathway-mediated chemo-sensitization and immunotherapy against tumor. International journal of pharmaceutics. 2024-06-17. PMID:38885778. |
the in situ-produced no upregulated the fas expression on the tumor cell surface, thereby sensitizing the fas/fasl pathway-mediated tumor cell apoptosis of dox. |
2024-06-17 |
2024-06-21 |
Not clear |
| Reiri Takeuchi, Takatoshi Nomura, Manabu Yaguchi, Chieko Taguchi, Itaru Suzuki, Haruka Suzuki, Hiroko Matsumoto, Yuichiro Okada, Kazumune Arikawa, Takato Nomoto, Koichi Hiratsuk. 18‑α‑glycyrrhetinic acid induces apoptosis in gingival fibroblasts exposed to phenytoin. Experimental and therapeutic medicine. vol 28. issue 1. 2024-06-13. PMID:38868612. |
these results demonstrated that 18α-ga induced apoptosis through the activation of the fas and tnf pathways in the death receptor signaling pathway in gingival fibroblasts treated with pht. |
2024-06-13 |
2024-06-15 |
human |
| Kim J Krott, Friedrich Reusswig, Matthias Dille, Evelyn Krüger, Simone Gorressen, Saoussen Karray, Amin Polzin, Malte Kelm, Jens W Fischer, Margitta Elver. Platelets Induce Cell Apoptosis of Cardiac Cells via FasL after Acute Myocardial Infarction. Biomedicines. vol 12. issue 5. 2024-05-25. PMID:38791039. |
further, we identified platelet fasl to induce cell apoptosis via the extrinsic pathway of fas receptor activation of target cells. |
2024-05-25 |
2024-05-27 |
mouse |
| Adarsha Koirala, Ann Marshak-Rothstein, Bruce R Ksander, Meredith Gregory-Ksande. Fas Ligand enhances vessel maturation and inhibits vascular leakage associated with age-related macular degeneration. Research square. 2024-05-20. PMID:38766158. |
previous studies suggested that fas ligand (fasl) on retinal pigment epithelial cells inhibited cnv by inducing apoptosis of infiltrating fas + vascular endothelial cells. |
2024-05-20 |
2024-05-27 |
mouse |
| Xueqin Huang, Eugenie Nepovimova, Vojtech Adam, Ladislav Sivak, Zbynek Heger, Marian Valko, Qinghua Wu, Kamil Kuc. Neutrophils in Cancer immunotherapy: friends or foes? Molecular cancer. vol 23. issue 1. 2024-05-18. PMID:38760815. |
they also modulate the expression of tumor necrosis factor-related apoptosis-inducing ligand and fas ligand, augmenting their capacity to induce tumor cell apoptosis. |
2024-05-18 |
2024-05-27 |
Not clear |
| Monika Szelest, Krzysztof Giannopoulo. Biological relevance of alternative splicing in hematologic malignancies. Molecular medicine (Cambridge, Mass.). vol 30. issue 1. 2024-05-17. PMID:38760666. |
finally, we provide an extensive overview of the biological relevance of aberrant isoforms of genes involved in the regulation of apoptosis (e. g. bcl-x, mcl-1, fas, and c-flip), activation of key cellular signaling pathways (casp8, map3k7, and notch2), and cell metabolism (pkm). |
2024-05-17 |
2024-05-27 |
Not clear |
| YuXin Feng, ZhengXinYu Liu, CaoYuan Han, JiaQian Chen, XinHao Lin, WangHao Du, Yu Zhang, BeiBei Dong, YiKai Zheng, KeXiang Lu, QingJian Lian. Ficus hirta Vahl. alleviate LPS induced apoptosis via down-regulating of MiR-411 in orange-spotted grouper (Epinephelus coioides) spleen cell. Developmental and comparative immunology. 2024-05-05. PMID:38705263. |
in this study, fas, an apoptosis receptor, was cloned, which included a 5'-utr of 39 bp, an orf of 951 bp, a protein of 316 amino acids, and a 3'-utr of 845 bp. |
2024-05-05 |
2024-05-08 |
Not clear |