All Relations between apoptosis and fas

Publication Sentence Publish Date Extraction Date Species
Ayman Hyder, Basma Sheta, Manar Eissa, Jürgen Schrezenmei. Silencing the FABP3 gene in insulin-secreting cells reduces fatty acid uptake and protects against lipotoxicity. Acta diabetologica. 2024-07-03. PMID:38960943. long-term exposure of pancreatic islets to fatty acids (fas), common in obesity, metabolic syndrome, and type 2 diabetes, leads to a compensatory hyperactivity followed by inflammation, apoptosis, dysfunctional beta cells, and results in insulin dependence of the patient. 2024-07-03 2024-07-10 Not clear
Mehmet H Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T Chan, Valeria I Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R Sewanan, In-Hyun Park, Laura E Niklason, Comert Kura. Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis. Cell death & disease. vol 15. issue 6. 2024-06-22. PMID:38909035. although fas is highly expressed in cancer cells, insufficient cell surface fas expression desensitizes cancer cells to fas-induced apoptosis. 2024-06-22 2024-06-25 mouse
Mehmet H Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Emily T Chan, Valeria I Arteaga Muniz, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo R Sewanan, In-Hyun Park, Laura E Niklason, Comert Kura. Mechano-inhibition of endocytosis sensitizes cancer cells to Fas-induced Apoptosis. Cell death & disease. vol 15. issue 6. 2024-06-22. PMID:38909035. here, we show that the increase in fas microaggregate formation on the plasma membrane in response to the inhibition of endocytosis sensitizes cancer cells to fas-induced apoptosis. 2024-06-22 2024-06-25 mouse
Wei Jiang, Tao-Tao Tang, Yi-Lin Zhang, Zuo-Lin Li, Yi Wen, Qin Yang, Yu-Qi Fu, Jing Song, Qiu-Li Wu, Min Wu, Bin Wang, Bi-Cheng Liu, Lin-Li L. CD8 T cells induce the peritubular capillary rarefaction during AKI to CKD transition. International journal of biological sciences. vol 20. issue 8. 2024-06-21. PMID:38904017. notably, cd8 t cells induced endothelial cell apoptosis via fas ligand-fas signaling. 2024-06-21 2024-06-23 mouse
Fei Wang, Shuheng Qin, Jiejie Zhang, Menglu Huang, Qin Liu, Peipei Xu, Yong H. Low-dose doxorubicin loaded extracellular vesicles combined Fas/FasL pathway-mediated chemo-sensitization and immunotherapy against tumor. International journal of pharmaceutics. 2024-06-17. PMID:38885778. the in situ-produced no upregulated the fas expression on the tumor cell surface, thereby sensitizing the fas/fasl pathway-mediated tumor cell apoptosis of dox. 2024-06-17 2024-06-21 Not clear
Reiri Takeuchi, Takatoshi Nomura, Manabu Yaguchi, Chieko Taguchi, Itaru Suzuki, Haruka Suzuki, Hiroko Matsumoto, Yuichiro Okada, Kazumune Arikawa, Takato Nomoto, Koichi Hiratsuk. 18‑α‑glycyrrhetinic acid induces apoptosis in gingival fibroblasts exposed to phenytoin. Experimental and therapeutic medicine. vol 28. issue 1. 2024-06-13. PMID:38868612. these results demonstrated that 18α-ga induced apoptosis through the activation of the fas and tnf pathways in the death receptor signaling pathway in gingival fibroblasts treated with pht. 2024-06-13 2024-06-15 human
Kim J Krott, Friedrich Reusswig, Matthias Dille, Evelyn Krüger, Simone Gorressen, Saoussen Karray, Amin Polzin, Malte Kelm, Jens W Fischer, Margitta Elver. Platelets Induce Cell Apoptosis of Cardiac Cells via FasL after Acute Myocardial Infarction. Biomedicines. vol 12. issue 5. 2024-05-25. PMID:38791039. further, we identified platelet fasl to induce cell apoptosis via the extrinsic pathway of fas receptor activation of target cells. 2024-05-25 2024-05-27 mouse
Adarsha Koirala, Ann Marshak-Rothstein, Bruce R Ksander, Meredith Gregory-Ksande. Fas Ligand enhances vessel maturation and inhibits vascular leakage associated with age-related macular degeneration. Research square. 2024-05-20. PMID:38766158. previous studies suggested that fas ligand (fasl) on retinal pigment epithelial cells inhibited cnv by inducing apoptosis of infiltrating fas + vascular endothelial cells. 2024-05-20 2024-05-27 mouse
Xueqin Huang, Eugenie Nepovimova, Vojtech Adam, Ladislav Sivak, Zbynek Heger, Marian Valko, Qinghua Wu, Kamil Kuc. Neutrophils in Cancer immunotherapy: friends or foes? Molecular cancer. vol 23. issue 1. 2024-05-18. PMID:38760815. they also modulate the expression of tumor necrosis factor-related apoptosis-inducing ligand and fas ligand, augmenting their capacity to induce tumor cell apoptosis. 2024-05-18 2024-05-27 Not clear
Monika Szelest, Krzysztof Giannopoulo. Biological relevance of alternative splicing in hematologic malignancies. Molecular medicine (Cambridge, Mass.). vol 30. issue 1. 2024-05-17. PMID:38760666. finally, we provide an extensive overview of the biological relevance of aberrant isoforms of genes involved in the regulation of apoptosis (e. g. bcl-x, mcl-1, fas, and c-flip), activation of key cellular signaling pathways (casp8, map3k7, and notch2), and cell metabolism (pkm). 2024-05-17 2024-05-27 Not clear
YuXin Feng, ZhengXinYu Liu, CaoYuan Han, JiaQian Chen, XinHao Lin, WangHao Du, Yu Zhang, BeiBei Dong, YiKai Zheng, KeXiang Lu, QingJian Lian. Ficus hirta Vahl. alleviate LPS induced apoptosis via down-regulating of MiR-411 in orange-spotted grouper (Epinephelus coioides) spleen cell. Developmental and comparative immunology. 2024-05-05. PMID:38705263. in this study, fas, an apoptosis receptor, was cloned, which included a 5'-utr of 39 bp, an orf of 951 bp, a protein of 316 amino acids, and a 3'-utr of 845 bp. 2024-05-05 2024-05-08 Not clear
YuXin Feng, ZhengXinYu Liu, CaoYuan Han, JiaQian Chen, XinHao Lin, WangHao Du, Yu Zhang, BeiBei Dong, YiKai Zheng, KeXiang Lu, QingJian Lian. Ficus hirta Vahl. alleviate LPS induced apoptosis via down-regulating of MiR-411 in orange-spotted grouper (Epinephelus coioides) spleen cell. Developmental and comparative immunology. 2024-05-05. PMID:38705263. inhibition of mir-411 further decreased the inhibitory effect of fas on apoptosis, which reduced bcl-2 expression and mitochondrial membrane potential, enhanced the protein expression of bax and fas. 2024-05-05 2024-05-08 Not clear
YuXin Feng, ZhengXinYu Liu, CaoYuan Han, JiaQian Chen, XinHao Lin, WangHao Du, Yu Zhang, BeiBei Dong, YiKai Zheng, KeXiang Lu, QingJian Lian. Ficus hirta Vahl. alleviate LPS induced apoptosis via down-regulating of MiR-411 in orange-spotted grouper (Epinephelus coioides) spleen cell. Developmental and comparative immunology. 2024-05-05. PMID:38705263. alleviates lps-induced apoptosis by activating mir-411 to inhibit fas expression and, therefore, provided possible strategies for bacterial infections in fish. 2024-05-05 2024-05-08 Not clear
Filippo Consonni, Solange Moreno, Blanca Vinuales Colell, Marie-Claude Stolzenberg, Alicia Fernandes, Mélanie Parisot, Cécile Masson, Nathalie Neveux, Jérémie Rosain, Sarah Bamberger, Marie-Gabrielle Vigue, Marion Malphettes, Pierre Quartier, Capucine Picard, Frédéric Rieux-Laucat, Aude Mageru. Study of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome. Cell death & disease. vol 15. issue 5. 2024-05-04. PMID:38704374. the genetic landscape of alps includes mutations in fas, faslg, and fadd, all associated with apoptosis deficiency, while the role of casp10 defect in the disease remains debated. 2024-05-04 2024-05-07 human
Filippo Consonni, Solange Moreno, Blanca Vinuales Colell, Marie-Claude Stolzenberg, Alicia Fernandes, Mélanie Parisot, Cécile Masson, Nathalie Neveux, Jérémie Rosain, Sarah Bamberger, Marie-Gabrielle Vigue, Marion Malphettes, Pierre Quartier, Capucine Picard, Frédéric Rieux-Laucat, Aude Mageru. Study of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome. Cell death & disease. vol 15. issue 5. 2024-05-04. PMID:38704374. comprehensive analyses of casp10 protein expression and fas-mediated apoptosis were conducted and compared to healthy controls and alps patients with fas mutations. 2024-05-04 2024-05-07 human
Filippo Consonni, Solange Moreno, Blanca Vinuales Colell, Marie-Claude Stolzenberg, Alicia Fernandes, Mélanie Parisot, Cécile Masson, Nathalie Neveux, Jérémie Rosain, Sarah Bamberger, Marie-Gabrielle Vigue, Marion Malphettes, Pierre Quartier, Capucine Picard, Frédéric Rieux-Laucat, Aude Mageru. Study of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome. Cell death & disease. vol 15. issue 5. 2024-05-04. PMID:38704374. moreover, the absence of fas expression up-regulation in subjects with casp10 variants rule out any compensatory mechanisms possibly involved in the normal apoptosis function observed. 2024-05-04 2024-05-07 human
Sophie I Worsfold, Kristyn Carter, Moeed Akbar, Lisa Hackett, Neal L Millar, George A C Murrel. Rotator Cuff Tendinopathy: Pathways of Apoptosis. Sports medicine and arthroscopy review. vol 32. issue 1. 2024-05-02. PMID:38695498. a prospective cohort study was conducted with 28 patients-14 rotator cuff tear patients, 5 instability patients, and 9 anterior cruciate ligament reconstruction patients to determine whether there was any increase in several genes implicated in apoptosis, including fas receptor (fasr), fas ligand, aifm-1, bcl-2, fadd, bax, and caspase-3. 2024-05-02 2024-05-04 Not clear
Chen Li, Zhiwen Sun, Hongjun Lou, Yenong Sun, Chengyuan Li, Xi Ga. Effects of miR-129-5p on inflammation and nucleus pulposus cell apoptosis in rats with intervertebral disc degeneration through JNK signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 4. 2024-04-28. PMID:38678607. the mrna expressions of mir-129-5p and apoptosis index fas in ivdd tissues were determined using rt-pcr. 2024-04-28 2024-05-01 rat
Danfeng Yu, Yanmei Ji, Jing Zhang, Xiaochuan Huan. TNFRSF6 induces mitochondrial dysfunction and microglia activation in the in vivo and in vitro models of sepsis-associated encephalopathy. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 3. 2024-04-23. PMID:38650148. the tumour necrosis factor receptor superfamily member 6 (tnfrsf6) gene encodes the fas protein, and it participates in apoptosis induced in different cell types. 2024-04-23 2024-04-26 mouse
Wael El Feky, Dalia El-Afify, Dina Abdelhai, Mohamed Elkashlan, Ahmed Fakhreldin, Doaa El Amrous. L-carnitine decreases myocardial injury in children undergoing open-heart surgery: A randomized controlled trial. European journal of pediatrics. 2024-04-03. PMID:38568244. blood samples were obtained pre-operatively at baseline before the administration of l-carnitine or placebo and 12 h post-operatively to measure the level of malondialdehyde (mda), superoxide dismutase (sod), fas, caspase-3, creatinine kinase-mb (ck-mb), and troponin i. l-carnitine group had significantly lower post-operative level of oxidative stress marker (mda), apoptosis markers (fas and caspase-3), and myocardial injury markers (ck-mb and troponin i), but they had significantly higher sod post-operative level compared to the control group. 2024-04-03 2024-04-05 Not clear