| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanheng Chen, Donald Sheppard, Xingchen Dong, Xiangming Hu, Meihua Chen, Ruichuan Chen, Jayati Chakrabarti, Yana Zavros, Richard M Peek, Lin-Feng Che. H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis. Cell death & disease. vol 11. issue 8. 2021-04-13. PMID:32820150. |
these results identify a novel function of brd4 in h. pylori-mediated apoptosis resistance via activating birc3 erna synthesis, suggesting that brd4 could be a potential therapeutic target for h. pylori-induced gastric cancer. |
2021-04-13 |
2023-08-13 |
human |
| Nan Jiang, Xinzhuo Zhang, Yancheng He, Bo Luo, Chengcheng He, Yu Liang, Jingyuan Zeng, Wei Li, Yujun Xian, Xiaoli Zhen. Identification of key protein-coding genes and lncRNAs in spontaneous neutrophil apoptosis. Scientific reports. vol 9. issue 1. 2020-10-28. PMID:31641174. |
protein-protein interaction (ppi) network analysis of the genes from 2 profiles and lncrna-mrna co-expression network analysis identified a 12-gene hub (including nfκb1 and birc3) associated with apoptosis, as well as 2 highly correlated lncrnas (thap9-as1, and al021707.6). |
2020-10-28 |
2023-08-13 |
Not clear |
| Zhi Wang, Mingming Zhong, Qiong Song, Laura E Pascal, Zhenyu Yang, Zeyu Wu, Ke Wang, Zhou Wan. Anti-apoptotic factor Birc3 is up-regulated by ELL2 knockdown and stimulates proliferation in LNCaP cells. American journal of clinical and experimental urology. vol 7. issue 4. 2020-10-01. PMID:31511829. |
to explore the mechanism of ell2 action in prostate cancer, we investigated the role of birc3, an apoptosis inhibitor, in prostate cancer cells and the regulation of its expression by ell2. |
2020-10-01 |
2023-08-13 |
mouse |
| Ting Xie, Wing Yan So, Xing Yu Li, Po Sing Leun. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism. Clinical science (London, England : 1979). vol 133. issue 19. 2020-05-25. PMID:31654570. |
interestingly, fgf21 reduced pa-induced cell death via restoration of the expression of apoptosis inhibitor birc3. |
2020-05-25 |
2023-08-13 |
mouse |
| Xiaoyan Hu, Yang Meng, Lian Xu, Lei Qiu, Mingtian Wei, Dan Su, Xu Qi, Ziqiang Wang, Shengyong Yang, Cong Liu, Junhong Ha. Cul4 E3 ubiquitin ligase regulates ovarian cancer drug resistance by targeting the antiapoptotic protein BIRC3. Cell death & disease. vol 10. issue 2. 2020-04-06. PMID:30718461. |
moreover, crl4 knockdown markedly inhibits the expression of birc3, one of the inhibitors of apoptosis proteins (iaps). |
2020-04-06 |
2023-08-13 |
Not clear |
| Jin-Yong Lee, Maki Tokumoto, Gi-Wook Hwang, Moo-Yeol Lee, Masahiko Sato. Identification of ARNT-regulated BIRC3 as the target factor in cadmium renal toxicity. Scientific reports. vol 7. issue 1. 2019-07-24. PMID:29229987. |
microarray analysis in arnt knockdown cells revealed a decrease in the expression of a number of genes, including a known apoptosis inhibitor, birc3, whose gene and protein expression level was also decreased by cd treatment. |
2019-07-24 |
2023-08-13 |
human |
| Jin-Yong Lee, Maki Tokumoto, Gi-Wook Hwang, Moo-Yeol Lee, Masahiko Sato. Identification of ARNT-regulated BIRC3 as the target factor in cadmium renal toxicity. Scientific reports. vol 7. issue 1. 2019-07-24. PMID:29229987. |
birc3 is known to suppress apoptosis through the inhibition effect on caspase-3. |
2019-07-24 |
2023-08-13 |
human |
| Jin-Yong Lee, Maki Tokumoto, Gi-Wook Hwang, Moo-Yeol Lee, Masahiko Sato. Identification of ARNT-regulated BIRC3 as the target factor in cadmium renal toxicity. Scientific reports. vol 7. issue 1. 2019-07-24. PMID:29229987. |
moreover, knockdown of birc3 not only triggered cell toxicity and apoptosis but also strengthened cd toxicity in hk-2 cells. |
2019-07-24 |
2023-08-13 |
human |
| Jin-Yong Lee, Maki Tokumoto, Gi-Wook Hwang, Moo-Yeol Lee, Masahiko Sato. Identification of ARNT-regulated BIRC3 as the target factor in cadmium renal toxicity. Scientific reports. vol 7. issue 1. 2019-07-24. PMID:29229987. |
these results suggest that cd induces apoptosis through the inhibition of arnt-regulated birc3 in human proximal tubular cells. |
2019-07-24 |
2023-08-13 |
human |
| Miran Rada, Sameera Nallanthighal, Jennifer Cha, Kerry Ryan, Jessica Sage, Catherine Eldred, Maria Ullo, Sandra Orsulic, Dong-Joo Cheo. Inhibitor of apoptosis proteins (IAPs) mediate collagen type XI alpha 1-driven cisplatin resistance in ovarian cancer. Oncogene. vol 37. issue 35. 2019-02-27. PMID:29769618. |
mechanistically, we show that col11a1 activates src-pi3k/akt-nf-kb signaling to induce the expression of three inhibitor apoptosis proteins (iaps), including xiap, birc2, and birc3. |
2019-02-27 |
2023-08-13 |
mouse |
| Miran Rada, Sameera Nallanthighal, Jennifer Cha, Kerry Ryan, Jessica Sage, Catherine Eldred, Maria Ullo, Sandra Orsulic, Dong-Joo Cheo. Inhibitor of apoptosis proteins (IAPs) mediate collagen type XI alpha 1-driven cisplatin resistance in ovarian cancer. Oncogene. vol 37. issue 35. 2019-02-27. PMID:29769618. |
genetic and pharmacological inhibition of xiap, birc2, and birc3 is sufficient to restore cisplatin-induced apoptosis in ovarian cancer cells in the presence of col11a1 in ovarian cancer cells and xenograft mouse models, respectively. |
2019-02-27 |
2023-08-13 |
mouse |
| Erasmia Rouk. Hypothesis: Is there a link between the immune response to Human Herpes Virus type 6Α (HHV-6Α) infection and the interaction network (interactome) of the genes encoding the CTSS, PTX3, CHI3L1, Mx1, CXCL16, BIRC3 and BST2 proteins? Medical hypotheses. vol 112. 2018-09-13. PMID:29447938. |
the genes encoding the ctss, ptx3, chi3l1, mx1, cxcl16, birc3 and bst2 proteins have been linked to hhv-6Α related neurologic diseases whilst also associated with apoptosis. |
2018-09-13 |
2023-08-13 |
human |
| Liping Wang, Yongxiang Wei, Yongyong Yan, Haiyan Wang, Jiantin Yang, Zhichao Zheng, Jun Zha, Peng Bo, Yinghua Tang, Xueqi Guo, Weihong Chen, Xinxin Zhu, Linhu G. CircDOCK1 suppresses cell apoptosis via inhibition of miR‑196a‑5p by targeting BIRC3 in OSCC. Oncology reports. vol 39. issue 3. 2018-08-28. PMID:29286141. |
circdock1 suppresses cell apoptosis via inhibition of mir‑196a‑5p by targeting birc3 in oscc. |
2018-08-28 |
2023-08-13 |
Not clear |
| Liping Wang, Yongxiang Wei, Yongyong Yan, Haiyan Wang, Jiantin Yang, Zhichao Zheng, Jun Zha, Peng Bo, Yinghua Tang, Xueqi Guo, Weihong Chen, Xinxin Zhu, Linhu G. CircDOCK1 suppresses cell apoptosis via inhibition of miR‑196a‑5p by targeting BIRC3 in OSCC. Oncology reports. vol 39. issue 3. 2018-08-28. PMID:29286141. |
both the silencing of circdock1 with small interfering rna and the upregulation of the expression of mir‑196a‑5p with mimics led oscc cells to increase apoptosis and decrease birc3 formation. |
2018-08-28 |
2023-08-13 |
Not clear |
| Liping Wang, Yongxiang Wei, Yongyong Yan, Haiyan Wang, Jiantin Yang, Zhichao Zheng, Jun Zha, Peng Bo, Yinghua Tang, Xueqi Guo, Weihong Chen, Xinxin Zhu, Linhu G. CircDOCK1 suppresses cell apoptosis via inhibition of miR‑196a‑5p by targeting BIRC3 in OSCC. Oncology reports. vol 39. issue 3. 2018-08-28. PMID:29286141. |
our results demonstrated that circdock1 regulated birc3 expression by functioning as a competing endogenous rna (cerna) and participated in the process of oscc apoptosis. |
2018-08-28 |
2023-08-13 |
Not clear |
| Zhi-Bin Tong, Helena Hogberg, David Kuo, Srilatha Sakamuru, Menghang Xia, Lena Smirnova, Thomas Hartung, David Gerhol. Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening. Journal of applied toxicology : JAT. vol 37. issue 2. 2017-12-15. PMID:27143523. |
gene expression results suggest that differentiating luhmes cells may be susceptible to apoptosis because they express low levels of anti-apoptotic genes bcl2 and birc5/survivin, whereas sh-sy5y cells may be resistant to apoptosis because they express high levels of bcl2, birc5/survivin, and birc3 genes. |
2017-12-15 |
2023-08-13 |
human |
| Aram Asatryan, Nicolas G Baza. Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. The Journal of biological chemistry. vol 292. issue 30. 2017-09-26. PMID:28615451. |
we summarize here how npd1 elicits neuroprotection by up-regulating c-rel, a nuclear factor (nf)-κb subtype that, in turn, enhances expression of birc3 (baculoviral inhibitor of apoptosis repeat-containing protein 3) in the retina and in experimental stroke, leading to neuroprotection. |
2017-09-26 |
2023-08-13 |
Not clear |
| Loyola V Gressot, Tiffany Doucette, Yuhui Yang, Gregory N Fuller, Ganiraju Manyam, Arvind Rao, Khatri Latha, Ganesh Ra. Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma. Oncotarget. vol 8. issue 8. 2017-09-18. PMID:27074575. |
analysis of the inhibitors of apoptosis identifies birc3 as a facilitator of malignant progression in glioma. |
2017-09-18 |
2023-08-13 |
mouse |
| Taro Yasuma, Yutaka Yano, Corina N D'Alessandro-Gabazza, Masaaki Toda, Paloma Gil-Bernabe, Tetsu Kobayashi, Kota Nishihama, Josephine A Hinneh, Rumi Mifuji-Moroka, Ziaurahman Roeen, John Morser, Isaac Cann, Iwasa Motoh, Yoshiyuki Takei, Esteban C Gabazz. Amelioration of Diabetes by Protein S. Diabetes. vol 65. issue 7. 2017-06-05. PMID:27207541. |
significant inhibition of apoptosis with increased expression of birc3 and bcl-2 and enhanced activation of akt/pkb was induced by protein s in islet β-cells compared with controls. |
2017-06-05 |
2023-08-13 |
mouse |
| Dapeng Wang, Anders Berglund, Rajappa S Kenchappa, Peter A Forsyth, James J Mulé, Arnold B Etam. BIRC3 is a novel driver of therapeutic resistance in Glioblastoma. Scientific reports. vol 6. 2017-03-02. PMID:26888114. |
lastly, we demonstrate that both in-vivo and in-vitro birc3 up-regulation results in apoptosis evasion and therapeutic resistance in gbm. |
2017-03-02 |
2023-08-13 |
human |