All Relations between Synucleinopathies and microtubule-associated protein tau
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Virginia M-Y Lee, Benoit I Giasson, John Q Trojanowsk. More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases. Trends in neurosciences. vol 27. issue 3. 2004-05-03. PMID:15036877. | thus, the ability of tau and alpha-synuclein to affect each other directly or indirectly might contribute to the overlap in the clinical and pathological features of tauopathies and synucleinopathies. | 2004-05-03 | 2023-08-12 | Not clear |
| Lawrence M Agiu. Are tau and alpha synuclein filamentous inclusions in neurons and glia analogous to accumulation of myosin/actin filaments in myofiber hypertrophy? Medical hypotheses. vol 60. issue 3. 2003-10-01. PMID:12581622. | in this sense, neurodegeneration as reflected in terms of neurofibrillary tangles and lewy bodies might actually be a process of integral tau opathy and synucleinopathy that in probably multiple different ways in the individual patient contributes to a disruption of neuronal interactions as an integral neuronal network. | 2003-10-01 | 2023-08-12 | Not clear |
| Mark S Forman, M Luise Schmidt, Sanjay Kasturi, Daniel P Perl, Virginia M-Y Lee, John Q Trojanowsk. Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam. The American journal of pathology. vol 160. issue 5. 2002-06-04. PMID:12000724. | tau and alpha-synuclein pathology within the amygdala is biochemically similar to that observed in ad and synucleinopathies, respectively. | 2002-06-04 | 2023-08-12 | Not clear |
| M Farrer, D M Maraganore, P Lockhart, A Singleton, T G Lesnick, M de Andrade, A West, R de Silva, J Hardy, D Hernande. alpha-Synuclein gene haplotypes are associated with Parkinson's disease. Human molecular genetics. vol 10. issue 17. 2002-01-15. PMID:11532993. | these genetic findings are analogous to the tau haplotype over-represented in progressive supranuclear palsy and further extend the similarity in the etiologies and pathogeneses of the synucleinopathies and tauopathies. | 2002-01-15 | 2023-08-12 | Not clear |