Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yuwei Han, Chenchen Wang, Xiaoming Li, Guobiao Lian. Oleanolic acid reduces oxidative stress and neuronal apoptosis after experimental subarachnoid hemorrhage by regulating Nrf2/HO-1 pathway. Drug development research. 2021-11-25. PMID:34820872. |
oxidative stress is an early major pathological feature after subarachnoid hemorrhage (sah) and involves in the development of acute brain injury, neuronal apoptosis and cerebral vasospasm following sah. |
2021-11-25 |
2023-08-13 |
rat |
Bao Zheng, Xiwei Zhou, Lujun Pang, Yanjun Che, Xin Q. Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage. Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34704542. |
early brain injury, characterized by massive cell apoptosis or death, is identified as a critical pathophysiological process during subarachnoid hemorrhage (sah). |
2021-11-23 |
2023-08-13 |
rat |
Cong Yan, Hongwei Yu, Yao Liu, Pei Wu, Chunlei Wang, Hongbo Zhao, Kongbin Yang, Qi Shao, Yingqiang Zhong, Wenyang Zhao, Jingwei Li, Nan Liu, Jinglong Di, Chen Li, Luhao Bao, Cheng Ga. c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway. Journal of molecular neuroscience : MN. vol 71. issue 12. 2021-11-19. PMID:33786723. |
c-abl tyrosine kinase-mediated neuronal apoptosis in subarachnoid hemorrhage by modulating the lrp-1-dependent akt/gsk3β survival pathway. |
2021-11-19 |
2023-08-13 |
Not clear |
Cong Yan, Hongwei Yu, Yao Liu, Pei Wu, Chunlei Wang, Hongbo Zhao, Kongbin Yang, Qi Shao, Yingqiang Zhong, Wenyang Zhao, Jingwei Li, Nan Liu, Jinglong Di, Chen Li, Luhao Bao, Cheng Ga. c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway. Journal of molecular neuroscience : MN. vol 71. issue 12. 2021-11-19. PMID:33786723. |
accumulating evidence suggests that neuronal apoptosis plays a critical role in early brain injury (ebi) after subarachnoid hemorrhage (sah), and the inhibition of apoptosis can induce neuroprotective effects in sah animal models. |
2021-11-19 |
2023-08-13 |
Not clear |
Shotaro Otsuka, Kentaro Setoyama, Seiya Takada, Kazuki Nakanishi, Takuto Terashi, Kosuke Norimatsu, Akira Tani, Harutoshi Sakakima, Ikuro Maruyama, Salunya Tancharoen, Eiichiro Tanaka, Kiyoshi Kikuch. Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34368932. |
preconditioning exercise in rats attenuates early brain injury resulting from subarachnoid hemorrhage by reducing oxidative stress, inflammation, and neuronal apoptosis. |
2021-11-18 |
2023-08-13 |
rat |
Xiaowei Chen, Xiaocheng Luo, Hang Hu, Qianghua X. NBTI attenuates neuroinflammation and apoptosis partly by ENT1/NLRP3/Bcl2 pathway after subarachnoid hemorrhage in rats. Neuroreport. vol 32. issue 17. 2021-11-16. PMID:34718248. |
nbti attenuates neuroinflammation and apoptosis partly by ent1/nlrp3/bcl2 pathway after subarachnoid hemorrhage in rats. |
2021-11-16 |
2023-08-13 |
rat |
Xiaowei Chen, Xiaocheng Luo, Hang Hu, Qianghua X. NBTI attenuates neuroinflammation and apoptosis partly by ENT1/NLRP3/Bcl2 pathway after subarachnoid hemorrhage in rats. Neuroreport. vol 32. issue 17. 2021-11-16. PMID:34718248. |
neuroinflammation and apoptosis are two key factors contributing to early brain injury (ebi) after subarachnoid hemorrhage (sah) and are strongly associated with a poor prognosis. |
2021-11-16 |
2023-08-13 |
rat |
Xiwei Zhou, Bao Zheng, Lujun Pang, Yanjun Che, Xin Q. Suppression of MALAT1 alleviates neurocyte apoptosis and reactive oxygen species production through the miR-499-5p/SOX6 axis in subarachnoid hemorrhage. Journal of molecular histology. 2021-10-28. PMID:34709490. |
suppression of malat1 alleviates neurocyte apoptosis and reactive oxygen species production through the mir-499-5p/sox6 axis in subarachnoid hemorrhage. |
2021-10-28 |
2023-08-13 |
mouse |
Lixiang Yang, Yue Wang, Can Zhang, Tao Chen, Huilin Chen. Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage‑induced brain injury via necroptosis and neuroinflammation. Molecular medicine reports. vol 24. issue 2. 2021-10-22. PMID:34080030. |
the alpha‑amino‑3‑hydroxy‑5‑methyl‑4‑isoxazolepropionic acid receptor antagonist perampanel has been reported to alleviate early brain injury following subarachnoid hemorrhage and traumatic brain injury by reducing reactive oxygen species, apoptosis, autophagy, and necroptosis. |
2021-10-22 |
2023-08-13 |
mouse |
Xian-Kun Tu, Quan Chen, Song Chen, Bin Huang, Bao-Gang Ren, Song-Sheng Sh. GLP-1R Agonist Liraglutide Attenuates Inflammatory Reaction and Neuronal Apoptosis and Reduces Early Brain Injury After Subarachnoid Hemorrhage in Rats. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32951103. |
glp-1r agonist liraglutide attenuates inflammatory reaction and neuronal apoptosis and reduces early brain injury after subarachnoid hemorrhage in rats. |
2021-10-07 |
2023-08-13 |
rat |
Yan Zhou, Tao Tao, Guangjie Liu, Xuan Gao, Yongyue Gao, Zong Zhuang, Yue Lu, Han Wang, Wei Li, Lingyun Wu, Dingding Zhang, Chunhua Han. TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways. Cell death & disease. vol 12. issue 1. 2021-09-30. PMID:33414375. |
traf3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting tak1-dependent mapks and nf-κb pathways. |
2021-09-30 |
2023-08-13 |
mouse |
Yan Zhou, Tao Tao, Guangjie Liu, Xuan Gao, Yongyue Gao, Zong Zhuang, Yue Lu, Han Wang, Wei Li, Lingyun Wu, Dingding Zhang, Chunhua Han. TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways. Cell death & disease. vol 12. issue 1. 2021-09-30. PMID:33414375. |
neuronal apoptosis has an important role in early brain injury (ebi) following subarachnoid hemorrhage (sah). |
2021-09-30 |
2023-08-13 |
mouse |
Felix Neumaier, Miriam Weiss, Michael Veldeman, Konstantin Kotliar, Martin Wiesmann, Henna Schulze-Steinen, Anke Höllig, Hans Clusmann, Gerrit Alexander Schubert, Walid Albann. Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage - Preliminary findings from an observational cohort study. Clinical neurology and neurosurgery. vol 208. 2021-09-15. PMID:34418701. |
aneurysmal subarachnoid hemorrhage (asah) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. |
2021-09-15 |
2023-08-13 |
Not clear |
Yuanjian Fang, Hui Shi, Lei Huang, Reng Ren, Cameron Lenahan, Jie Xiao, Yu Liu, Rui Liu, Rajvee Sanghavi, Chenguang Li, Sheng Chen, Jiping Tang, Jun Yu, John H Zhang, Jianmin Zhan. Pituitary adenylate cyclase-activating polypeptide attenuates mitochondria-mediated oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats. Free radical biology & medicine. vol 174. 2021-09-09. PMID:34400297. |
pituitary adenylate cyclase-activating polypeptide attenuates mitochondria-mediated oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats. |
2021-09-09 |
2023-08-13 |
rat |
Yuanjian Fang, Hui Shi, Lei Huang, Reng Ren, Cameron Lenahan, Jie Xiao, Yu Liu, Rui Liu, Rajvee Sanghavi, Chenguang Li, Sheng Chen, Jiping Tang, Jun Yu, John H Zhang, Jianmin Zhan. Pituitary adenylate cyclase-activating polypeptide attenuates mitochondria-mediated oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats. Free radical biology & medicine. vol 174. 2021-09-09. PMID:34400297. |
mitochondria-mediated oxidative stress and neuronal apoptosis play an important role in early brain injury following subarachnoid hemorrhage (sah). |
2021-09-09 |
2023-08-13 |
rat |
Xuan Gao, Yong-Yue Gao, Hui-Ying Yan, Guang-Jie Liu, Yan Zhou, Tao Tao, Ting-Ting Yue, Cong Pang, Xiang-Xin Chen, Sen Gao, Ling-Yun Wu, Chun-Hua Hang, Wei L. PDK4 decrease neuronal apoptosis via inhibiting ROS-ASK1/p38 pathway in early brain injury after subarachnoid hemorrhage. Antioxidants & redox signaling. 2021-09-09. PMID:34498942. |
pdk4 decrease neuronal apoptosis via inhibiting ros-ask1/p38 pathway in early brain injury after subarachnoid hemorrhage. |
2021-09-09 |
2023-08-13 |
Not clear |
Xuan Gao, Yong-Yue Gao, Hui-Ying Yan, Guang-Jie Liu, Yan Zhou, Tao Tao, Ting-Ting Yue, Cong Pang, Xiang-Xin Chen, Sen Gao, Ling-Yun Wu, Chun-Hua Hang, Wei L. PDK4 decrease neuronal apoptosis via inhibiting ROS-ASK1/p38 pathway in early brain injury after subarachnoid hemorrhage. Antioxidants & redox signaling. 2021-09-09. PMID:34498942. |
metabolic disorders may play key roles in oxidative stress and neuronal apoptosis in response to early brain injury (ebi) after subarachnoid hemorrhage (sah). |
2021-09-09 |
2023-08-13 |
Not clear |
Yang Wang, Xiang-Qian Kong, Fei Wu, Bin Xu, De-Jun Bao, Chuan-Dong Cheng, Xiang-Ping Wei, Yong-Fei Dong, Chao-Shi Ni. SOCS1/JAK2/STAT3 axis regulates early brain injury induced by subarachnoid hemorrhage via inflammatory responses. Neural regeneration research. vol 16. issue 12. 2021-08-26. PMID:33907034. |
si-jak2 and si-stat3 treatment alleviated cortical neuronal cell apoptosis and necrosis, destruction of the blood-brain barrier, brain edema, and cognitive functional impairment after subarachnoid hemorrhage. |
2021-08-26 |
2023-08-13 |
rat |
Guangyao Shi, Lei Cui, Rui Chen, Shaodong Liang, Chunlei Wang, Pei W. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction after subarachnoid hemorrhage in rats. Neuroreport. vol 31. issue 11. 2021-08-16. PMID:32604395. |
tt01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoneet-mediated mitochondrial dysfunction after subarachnoid hemorrhage in rats. |
2021-08-16 |
2023-08-13 |
rat |
Guangyao Shi, Lei Cui, Rui Chen, Shaodong Liang, Chunlei Wang, Pei W. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction after subarachnoid hemorrhage in rats. Neuroreport. vol 31. issue 11. 2021-08-16. PMID:32604395. |
oxidative stress and neuronal apoptosis are considered crucial therapeutic targets against early brain injury (ebi) after subarachnoid hemorrhage (sah). |
2021-08-16 |
2023-08-13 |
rat |