| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gang Zuo, Tongyu Zhang, Lei Huang, Camila Araujo, Jun Peng, Zachary Travis, Takeshi Okadab, Umut Ocak, Guangyu Zhang, Jiping Tang, Xiaojun Lu, John H Zhan. Corrigendum to "Activation of TGR5 with INT-777 attenuates oxidative stress and neuronal apoptosis via cAMP/PKCε/ALDH2 pathway after subarachnoid hemorrhage in rats" [Free Radic. Biol. Med. (2019 Nov 1) 143 441-453]. Free radical biology & medicine. vol 216. 2024-03-19. PMID:38502984. |
corrigendum to "activation of tgr5 with int-777 attenuates oxidative stress and neuronal apoptosis via camp/pkcε/aldh2 pathway after subarachnoid hemorrhage in rats" [free radic. |
2024-03-19 |
2024-03-23 |
rat |
| Jiaqiang Liu, Zihuan Zhang, Mengliang Zhou, Shizhang Ling, Xiaoming Zhou, Bin Yuan, Xintong Zhao, Min Qi, Yanling Han, Feiyun Qin, Zhenbao L. TREM2 Alleviates Subarachnoid Hemorrhage-Induced Brain Injury through Attenuating Neuroinflammation and Programmed Cell Death Frontiers in bioscience (Landmark edition). vol 29. issue 2. 2024-02-29. PMID:38420821. |
trem2 alleviates subarachnoid hemorrhage-induced brain injury through attenuating neuroinflammation and programmed cell death apoptosis and pyroptosis are two types of programmed cell death related to the neuroinflammatory reaction after subarachnoid hemorrhage (sah). |
2024-02-29 |
2024-03-02 |
Not clear |
| Yan Wu, Yao Xu, Jingshan Sun, Kun Dai, Zhong Wang, Jian Zhan. Inhibiting RIPK1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage. Experimental neurology. 2024-01-30. PMID:38290652. |
inhibiting ripk1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage. |
2024-01-30 |
2024-02-02 |
mouse |
| Yan Wu, Yao Xu, Jingshan Sun, Kun Dai, Zhong Wang, Jian Zhan. Inhibiting RIPK1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage. Experimental neurology. 2024-01-30. PMID:38290652. |
neuroinflammation and neuronal apoptosis are two pivotal factors in the pathogenesis of brain injury following subarachnoid hemorrhage (sah). |
2024-01-30 |
2024-02-02 |
mouse |
| Fumi Nakano, Hideki Kanamaru, Fumihiro Kawakita, Lei Liu, Yoshinari Nakatsuka, Hirofumi Nishikawa, Takeshi Okada, Hidenori Suzuk. Epidermal Growth Factor Receptor Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage in Mice. Stroke. 2023-05-08. PMID:37154060. |
epidermal growth factor receptor mediates neuronal apoptosis after subarachnoid hemorrhage in mice. |
2023-05-08 |
2023-08-14 |
mouse |
| Fumi Nakano, Hideki Kanamaru, Fumihiro Kawakita, Lei Liu, Yoshinari Nakatsuka, Hirofumi Nishikawa, Takeshi Okada, Hidenori Suzuk. Epidermal Growth Factor Receptor Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage in Mice. Stroke. 2023-05-08. PMID:37154060. |
early brain injury including neuronal apoptosis is a main contributor to neurological deterioration after subarachnoid hemorrhage (sah). |
2023-05-08 |
2023-08-14 |
mouse |
| Ali Akar, Rahime Özlem Öztopuz, Başak Büyük, Mehmet Akif Ovali, Damla Aykora, Ümit Ali Malço. Neuroprotective Effects of Piceatannol on Olfactory Bulb Injury after Subarachnoid Hemorrhage. Molecular neurobiology. 2023-03-18. PMID:36933146. |
in this study, we aimed to investigate the potential therapeutic effects of pic on ob injury following sah at molecular mechanism based on sirt1, inflammatory (tnf-α, il1-β, nf-κb, il-6, tlr4), and apoptosis (p53, bax, bcl-2, caspase-3)-related gene expression markers and histopathology level; 27 male wistar albino rats were used in a pre-chiasmatic subarachnoid hemorrhage model. |
2023-03-18 |
2023-08-14 |
rat |
| Fumihiro Kawakita, Fumi Nakano, Hideki Kanamaru, Reona Asada, Hidenori Suzuk. Anti-Apoptotic Effects of AMPA Receptor Antagonist Perampanel in Early Brain Injury After Subarachnoid Hemorrhage in Mice. Translational stroke research. 2023-02-09. PMID:36757633. |
this study was aimed to investigate if acute neuronal apoptosis is induced by activation of ampa (α-amino-3-hydroxy-5-methyl-4-isoxazole propionate) receptors (ampars) and inhibited by a clinically available selective ampar antagonist and antiepileptic drug perampanel (per) in subarachnoid hemorrhage (sah), and if the mechanisms include upregulation of an inflammation-related matricellular protein periostin. |
2023-02-09 |
2023-08-14 |
mouse |
| Qi Tian, Yujia Guo, Shi Feng, Chengli Liu, Peibang He, Jianfeng Wang, Wenrui Han, Chen Yang, Zhan Zhang, Mingchang L. Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-12-24. PMID:36566220. |
inhibition of ccr2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the pi3k/akt pathway. |
2022-12-24 |
2023-08-14 |
Not clear |
| Qi Tian, Yujia Guo, Shi Feng, Chengli Liu, Peibang He, Jianfeng Wang, Wenrui Han, Chen Yang, Zhan Zhang, Mingchang L. Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-12-24. PMID:36566220. |
neuroinflammation and neuronal apoptosis are closely associated with a poor prognosis in patients with subarachnoid hemorrhage (sah). |
2022-12-24 |
2023-08-14 |
Not clear |
| Xiao-Yi Wang, Fan Wu, Ren-Ya Zhan, Heng-Jun Zho. Inflammatory role of microglia in brain injury caused by subarachnoid hemorrhage. Frontiers in cellular neuroscience. vol 16. 2022-12-23. PMID:36561497. |
microglia are involved in the occurrence of brain edema, the processes of neuronal apoptosis, and the blood-brain barrier disruption after subarachnoid hemorrhage (sah) through the signaling pathways mediated by receptors such as toll-like receptor 4 (tlr4), calcium-sensing receptor (casr), and triggering receptor expressed on myeloid cells-1 (trem-1), which secrete pro-inflammatory cytokines such as interleukins and tumor necrosis factor α. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yu Liu, Rui Liu, Lei Huang, Gang Zuo, Jiaxing Dai, Ling Gao, Hui Shi, Yuanjian Fang, Qin Lu, Takeshi Okada, Zhifei Wang, Xiao Hu, Cameron Lenahan, Jiping Tang, Jie Xiao, John H Zhan. Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats. Oxidative medicine and cellular longevity. vol 2022. 2022-12-19. PMID:36531208. |
inhibition of prostaglandin e2 receptor ep3 attenuates oxidative stress and neuronal apoptosis partially by modulating p38mapk/foxo3/mul1/mfn2 pathway after subarachnoid hemorrhage in rats. |
2022-12-19 |
2023-08-14 |
rat |
| Yu Liu, Rui Liu, Lei Huang, Gang Zuo, Jiaxing Dai, Ling Gao, Hui Shi, Yuanjian Fang, Qin Lu, Takeshi Okada, Zhifei Wang, Xiao Hu, Cameron Lenahan, Jiping Tang, Jie Xiao, John H Zhan. Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats. Oxidative medicine and cellular longevity. vol 2022. 2022-12-19. PMID:36531208. |
oxidative stress and neuronal apoptosis contribute to pathological processes of early brain injury (ebi) after subarachnoid hemorrhage (sah). |
2022-12-19 |
2023-08-14 |
rat |
| Zihuan Zhang, Jincheng Fang, Jiawang Zhou, Fei Ding, Gang Zhou, Xintong Zhao, Zong Zhuang, Yue L. Pterostilbene Attenuates Subarachnoid Hemorrhage-Induced Brain Injury through the SIRT1-Dependent Nrf2 Signaling Pathway. Oxidative medicine and cellular longevity. vol 2022. 2022-12-12. PMID:36506933. |
neuroinflammatory injury, oxidative insults, and neuronal apoptosis are major causes of poor outcomes after subarachnoid hemorrhage (sah). |
2022-12-12 |
2023-08-14 |
Not clear |
| Junjia Tang, Yichao Jin, Feng Jia, Tao Lv, Anatol Manaenko, Lin-Feng Zhang, Zeyu Zhang, Xin Qi, Yajun Xue, Bin Zhao, Xiaohua Zhang, John H Zhang, Jianfei Lu, Qin H. Gas6 Promotes Microglia Efferocytosis and Suppresses Inflammation Through Activating Axl/Rac1 Signaling in Subarachnoid Hemorrhage Mice. Translational stroke research. 2022-11-03. PMID:36324028. |
early brain injury (ebi) following subarachnoid hemorrhage (sah) is characterized by rapid development of neuron apoptosis and dysregulated inflammatory response. |
2022-11-03 |
2023-08-14 |
mouse |
| Shuangying Hao, Xingying Chen, Dingding Zhang, Wenting Song, Yan Zhou, Zhiqing Yuan, Zhiqiang Liu, Xiaojing Yue, Shuai Yua. GSK3β inhibitor TDZD8 ameliorates brain damage through both ROS scavenging and inhibition of apoptosis in hyperglycemic subarachnoid hemorrhage rats. Clinical and experimental pharmacology & physiology. 2022-09-15. PMID:36106766. |
gsk3β inhibitor tdzd8 ameliorates brain damage through both ros scavenging and inhibition of apoptosis in hyperglycemic subarachnoid hemorrhage rats. |
2022-09-15 |
2023-08-14 |
rat |
| Catherine Peterson, Alexis O Umoye, Chloe H Puglisi, Ben Walda. Mechanisms of memory impairment in animal models of nontraumatic intracranial hemorrhage: A systematic review of the literature. Brain hemorrhages. vol 3. issue 2. 2022-09-12. PMID:36093312. |
most of subarachnoid hemorrhage studies (30%) reported neuronal apoptosis as a mechanism for memory dysfunction, whereas the most commonly described mechanism following intraparenchymal hemorrhage (40%) and intraventricular hemorrhage (23%) was a proinflammatory response. |
2022-09-12 |
2023-08-14 |
Not clear |
| Peng-Fei Ding, Qi Zhu, Bin Sheng, Heng Yang, Hua-Jie Xu, Tao Tao, Zheng Peng, Xiang-Xin Chen, Xiao-Jian Li, Yan Zhou, Hua-Sheng Zhang, Yong-Yue Gao, Zong Zhuang, Chun-Hua Hang, Wei L. Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage. Oxidative medicine and cellular longevity. vol 2022. 2022-09-05. PMID:36062190. |
alpha-ketoglutarate alleviates neuronal apoptosis induced by central insulin resistance through inhibiting s6k1 phosphorylation after subarachnoid hemorrhage. |
2022-09-05 |
2023-08-14 |
Not clear |
| Peng-Fei Ding, Qi Zhu, Bin Sheng, Heng Yang, Hua-Jie Xu, Tao Tao, Zheng Peng, Xiang-Xin Chen, Xiao-Jian Li, Yan Zhou, Hua-Sheng Zhang, Yong-Yue Gao, Zong Zhuang, Chun-Hua Hang, Wei L. Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage. Oxidative medicine and cellular longevity. vol 2022. 2022-09-05. PMID:36062190. |
neuronal apoptosis after subarachnoid hemorrhage (sah) is believed to play an important role in early brain injury after sah. |
2022-09-05 |
2023-08-14 |
Not clear |
| Qi Tian, Sheng Liu, Shou-Meng Han, Wei Zhang, Xian-Yao Qin, Jun-Hui Chen, Cheng-Li Liu, Yu-Jia Guo, Ming-Chang L. The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage. Neural regeneration research. vol 18. issue 2. 2022-07-28. PMID:35900398. |
the mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage. |
2022-07-28 |
2023-08-14 |
Not clear |