| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yaqiong Chai, Adam M Bush, Julie Coloigner, Aart J Nederveen, Benita Tamrazi, Chau Vu, Soyoung Choi, Thomas D Coates, Natasha Lepore, John C Woo. White matter has impaired resting oxygen delivery in sickle cell patients. American journal of hematology. vol 94. issue 4. 2019-12-20. PMID:30697803. |
although modern medical management has lowered overt stroke occurrence in patients with sickle cell disease (scd), progressive white matter (wm) damage remains common. |
2019-12-20 |
2023-08-13 |
human |
| Marianne E McPherson Yee, Erin K Meyer, Ross M Fasano, Peter A Lane, Cassandra D Josephson, Angela G Breg. Health literacy and knowledge of chronic transfusion therapy in adolescents with sickle cell disease and caregivers. Pediatric blood & cancer. vol 66. issue 7. 2019-12-17. PMID:30941859. |
patients with sickle cell disease (scd) may require chronic transfusion therapy (ctt) for prevention of stroke or other complications. |
2019-12-17 |
2023-08-13 |
Not clear |
| Eric J Niesor, Renée Benghozi, Philippe Amouyel, Keith C Ferdinand, Gregory G Schwart. Adenylyl Cyclase 9 Polymorphisms Reveal Potential Link to HDL Function and Cardiovascular Events in Multiple Pathologies: Potential Implications in Sickle Cell Disease. Cardiovascular drugs and therapy. vol 29. issue 6. 2019-11-20. PMID:26619842. |
moreover, adcy9 polymorphism is associated with risk of stroke in scd. |
2019-11-20 |
2023-08-13 |
Not clear |
| Caterina P Minniti, Vinod K Gidvani, Dorothy Bulas, Wendy A Brown, Gilbert Vezina, M Catherine Driscol. Transcranial Doppler Changes in Children With Sickle Cell Disease on Transfusion Therapy. Journal of pediatric hematology/oncology. vol 26. issue 10. 2019-11-20. PMID:27811602. |
transcranial doppler (tcd) is an effective method for screening patients with sickle cell disease (scd) at risk for first stroke. |
2019-11-20 |
2023-08-13 |
Not clear |
| Michelle Downes, Fenella J Kirkham, Paul T Telfer, Michelle de Haa. Altered Neurophysiological Processing of Auditory Attention in Preschool Children With Sickle Cell Disease. Journal of pediatric psychology. vol 43. issue 8. 2019-11-15. PMID:29048550. |
sickle cell disease (scd) is a genetic red blood cell disorder that often leads to stroke and executive dysfunction in school-age children and adults. |
2019-11-15 |
2023-08-13 |
Not clear |
| IkeOluwa Lagunju, B J Brown, A O Oyinlade, A Asinobi, J Ibeh, A Esione, O O Sodeind. Annual stroke incidence in Nigerian children with sickle cell disease and elevated TCD velocities treated with hydroxyurea. Pediatric blood & cancer. vol 66. issue 3. 2019-11-12. PMID:29797633. |
elevated transcranial doppler (tcd) velocities accurately predict stroke risk in children with sickle cell disease (scd). |
2019-11-12 |
2023-08-13 |
Not clear |
| Kenzaburo Nakajima, Takeshi Aiba, Takeru Makiyama, Suguru Nishiuchi, Seiko Ohno, Koichi Kato, Yuta Yamamoto, Takahiro Doi, Satoshi Shizuta, Kenji Onoue, Nobue Yagihara, Taisuke Ishikawa, Ichiro Watanabe, Hiroshi Kawakami, Yasushi Oginosawa, Nobuyuki Murakoshi, Akihiko Nogami, Kazutaka Aonuma, Yoshihiko Saito, Takeshi Kimura, Satoshi Yasuda, Naomasa Makita, Wataru Shimizu, Minoru Horie, Kengo Kusan. Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry. Circulation journal : official journal of the Japanese Circulation Society. vol 82. issue 11. 2019-11-12. PMID:30078822. |
furthermore, during follow-up, 17 patients died: 12 end-stage heart failure, 4 scd and 1 stroke. |
2019-11-12 |
2023-08-13 |
human |
| Brenda M Martin, Lisa N Thaniel, Barbara J Speller-Brown, Deepika S Darbar. Comprehensive Infant Clinic for Sickle Cell Disease: Outcomes and Parental Perspective. Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners. vol 32. issue 5. 2019-10-21. PMID:30180940. |
comprehensive care for children with sickle cell disease (scd) includes penicillin prophylaxis, pneumococcal immunization, hydroxyurea therapy, and transcranial doppler screening for stroke prevention. |
2019-10-21 |
2023-08-13 |
Not clear |
| Adekunle Adekile, Meaad Hassan, Akram Asbeutah, Mohamed Al-Hinai, Omar Trad, Nayef Farha. Transcranial Doppler Ultrasound in Peninsular Arab Patients With Sickle Cell Disease. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. vol 38. issue 1. 2019-04-22. PMID:29732592. |
transcranial doppler ultrasound is used to identify patients with sickle cell disease (scd) at risk for stroke. |
2019-04-22 |
2023-08-13 |
Not clear |
| Luke R Smart, Arielle G Hernandez, Russell E War. Sickle cell disease: Translating clinical care to low-resource countries through international research collaborations. Seminars in hematology. vol 55. issue 2. 2019-04-09. PMID:30616806. |
as a result numerous well-established, cost-effective, and evidence-based strategies for managing scd such as newborn screening, early education, vaccinations, screening for stroke prevention, and treatments with safe transfusions and hydroxyurea are often unavailable, leading to substantial morbidity and increased mortality. |
2019-04-09 |
2023-08-13 |
Not clear |
| Mohsen Saleh ElAlfy, Fatma Soliman Elsayed Ebeid, Tarek Mostafa Kamal, Deena Samir Eissa, Eman Abdel Rahman Ismail, Samar Hassan Mohame. Angiotensinogen M235T Gene Polymorphism is a Genetic Determinant of Cerebrovascular and Cardiopulmonary Morbidity in Adolescents with Sickle Cell Disease. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 28. issue 2. 2019-01-28. PMID:30409744. |
cerebrovascular stroke is a common critical complication of sickle cell disease (scd). |
2019-01-28 |
2023-08-13 |
Not clear |
| Laurence Dedeken, Phu Quoc Lê, Laurence Rozen, Hanane El Kenz, Sophie Huybrechts, Christine Devalck, Safiatou Diallo, Catherine Heijmans, Alina Ferste. Automated RBC exchange compared to manual exchange transfusion for children with sickle cell disease is cost-effective and reduces iron overload. Transfusion. vol 58. issue 6. 2018-12-17. PMID:29574950. |
chronic transfusion in sickle cell disease (scd) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. |
2018-12-17 |
2023-08-13 |
Not clear |
| Shaun Lawicki, Laura Craig-Owens, Peter R Bream, Quentin Eichbau. Indwelling ports for prophylactic RBC exchanges in sickle cell patients: Comparison of bard and vortex ports. Journal of clinical apheresis. vol 33. issue 6. 2018-12-17. PMID:30387237. |
red blood cell exchange (rce) procedures are commonly used for stroke prevention in sickle cell disease (scd) patients. |
2018-12-17 |
2023-08-13 |
Not clear |
| Catherine Amlie-Lefond, Jonathan Flanagan, Julie Kanter, William B Dobyn. The Genetic Landscape of Cerebral Steno-Occlusive Arteriopathy and Stroke in Sickle Cell Anemia. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 27. issue 11. 2018-12-11. PMID:30076115. |
stroke is a common and serious complication of scd, most often associated with steno-occlusive cerebral arteriopathy, but little is known about its pathogenesis. |
2018-12-11 |
2023-08-13 |
Not clear |
| Catherine Amlie-Lefond, Jonathan Flanagan, Julie Kanter, William B Dobyn. The Genetic Landscape of Cerebral Steno-Occlusive Arteriopathy and Stroke in Sickle Cell Anemia. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 27. issue 11. 2018-12-11. PMID:30076115. |
while sibling studies have shown a strong genetic contribution to the development of steno-occlusive arteriopathy (soa) in scd, the only genome-wide association study compared a relatively small cohort of 177 patients with stroke to 335 patients with no history of stroke. |
2018-12-11 |
2023-08-13 |
Not clear |
| Catherine Amlie-Lefond, Jonathan Flanagan, Julie Kanter, William B Dobyn. The Genetic Landscape of Cerebral Steno-Occlusive Arteriopathy and Stroke in Sickle Cell Anemia. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 27. issue 11. 2018-12-11. PMID:30076115. |
dissecting the molecular causes of stroke in scd will provide valuable information that can be used to better prevent stroke, stratify risk of soa, and optimize personalized medicine approaches. |
2018-12-11 |
2023-08-13 |
Not clear |
| Rejane de Souza Macedo-Campos, Samuel Ademola Adegoke, Maria Stella Figueiredo, Josefina Aparecida Pellegrini Braga, Gisele Sampaio Silv. Cerebral Vasoreactivity in Children with Sickle Cell Disease: A Transcranial Doppler Study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 27. issue 10. 2018-11-26. PMID:30049518. |
impairment of vasodilatory capacity reflecting reduced cerebrovascular reserve was previously shown in adults with sickle cell disease (scd) and might play a role in the pathophysiology of stroke in such patients. |
2018-11-26 |
2023-08-13 |
Not clear |
| Laura M Raffield, Jacob C Ulirsch, Rakhi P Naik, Samuel Lessard, Robert E Handsaker, Deepti Jain, Hyun M Kang, Nathan Pankratz, Paul L Auer, Erik L Bao, Joshua D Smith, Leslie A Lange, Ethan M Lange, Yun Li, Timothy A Thornton, Bessie A Young, Goncalo R Abecasis, Cathy C Laurie, Deborah A Nickerson, Steven A McCarroll, Adolfo Correa, James G Wilson, Guillaume Lettre, Vijay G Sankaran, Alex P Reine. Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. PLoS genetics. vol 14. issue 3. 2018-06-26. PMID:29590102. |
co-inheritance of α-thalassemia has a significant protective effect on the severity of complications of sickle cell disease (scd), including stroke. |
2018-06-26 |
2023-08-13 |
Not clear |
| Nicola Conran, John D Belche. Inflammation in sickle cell disease. Clinical hemorheology and microcirculation. vol 68. issue 2-3. 2018-05-29. PMID:29614637. |
in addition to their role in the initiation of the acute painful vaso-occlusive episodes that are characteristic of scd, inflammatory processes are also key components of many of the complications of the disease including autosplenectomy, acute chest syndrome, pulmonary hypertension, leg ulcers, nephropathy and stroke. |
2018-05-29 |
2023-08-13 |
Not clear |
| Jeffrey Schatz, Alyssa M Schlenz, Kelsey E Smith, Carla W Robert. Predictive validity of developmental screening in young children with sickle cell disease: a longitudinal follow-up study. Developmental medicine and child neurology. vol 60. issue 5. 2018-05-21. PMID:29488622. |
to assess the predictive validity of developmental screenings in children with sickle cell disease (scd) for academic outcomes and stroke risk. |
2018-05-21 |
2023-08-13 |
Not clear |