| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Olivia Edwards, Alicia Burris, Josh Lua, Diana J Wilkie, Miriam O Ezenwa, Sylvain Dor\\xc3\\xa. Influence of Haptoglobin Polymorphism on Stroke in Sickle Cell Disease Patients. Genes. vol 13. issue 1. 2022-01-21. PMID:35052484.' |
the role of hp in patients with scd is critical in combating blood toxicity, inflammation, oxidative stress, and even stroke. |
2022-01-21 |
2023-08-13 |
Not clear |
| b' Olivia Edwards, Alicia Burris, Josh Lua, Diana J Wilkie, Miriam O Ezenwa, Sylvain Dor\\xc3\\xa. Influence of Haptoglobin Polymorphism on Stroke in Sickle Cell Disease Patients. Genes. vol 13. issue 1. 2022-01-21. PMID:35052484.' |
this review is the first to evaluate the role of the hp polymorphism in the incidence of stroke in patients with scd. |
2022-01-21 |
2023-08-13 |
Not clear |
| Eboni I Lance, Lisa M Faulcon, Zongming Fu, Jun Yang, Donna Whyte-Stewart, John J Strouse, Emily Barron-Casella, Kimberly Jones, Jennifer E Van Eyk, James F Casella, Allen D Everet. Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease. Proteomics. Clinical applications. vol 15. issue 5. 2021-11-17. PMID:33915030. |
sickle cell disease (scd) is an inherited hemoglobinopathy that causes stroke and silent cerebral infarct (sci). |
2021-11-17 |
2023-08-13 |
Not clear |
| Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
children with scd have a 300-fold higher risk of acute stroke and by the age of 45 about 25% of patients have suffered an overt stoke. |
2021-11-11 |
2023-08-13 |
Not clear |
| Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
management and prevention of stroke in patients with scd is not well defined. |
2021-11-11 |
2023-08-13 |
Not clear |
| Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
moreover, during covid-19 pandemic and taking into account the increased rates of thrombotic events and the difficulties in blood transfusion, management of scd patients is even more challenging and difficult, since data are scarce regarding stroke occurrence and management in this specific population in the covid-19 era. |
2021-11-11 |
2023-08-13 |
Not clear |
| Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
this review focuses on pathophysiology of stroke in patients with scd and possible treatment strategies in the presence of pfo. |
2021-11-11 |
2023-08-13 |
Not clear |
| Jacob A Smith, Jansen N Seheult, Joan Sevcik, Joseph E Kiss, Alesia Kapla. Process mapping of the urgent red cell exchange procedure for patients with severe complications of sickle cell disease at a centralized hemapheresis service. Journal of clinical apheresis. vol 35. issue 5. 2021-11-03. PMID:32767846. |
a retrospective review of patients with scd requiring urgent rce for acs and stroke from 2012 to 2017 was performed at a centralized hemapheresis service covering a multihospital healthcare system. |
2021-11-03 |
2023-08-13 |
Not clear |
| Sarah L Mayer, Melanie E Fields, Monica L Hulber. Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence. NeoReviews. vol 22. issue 8. 2021-11-02. PMID:34341160. |
current treatment for scd focuses on primary prevention of complications, such as hydroxyurea for prevention of pain and acute chest syndrome, and chronic transfusion therapy for children who are at high risk for strokes. |
2021-11-02 |
2023-08-13 |
Not clear |
| James M Shikany, Monika M Safford, Orysya Soroka, Todd M Brown, P K Newby, Raegan W Durant, Suzanne E Jud. Mediterranean Diet Score, Dietary Patterns, and Risk of Sudden Cardiac Death in the REGARDS Study. Journal of the American Heart Association. vol 10. issue 13. 2021-11-01. PMID:34189926. |
we investigated the associations of the mediterranean diet score and various dietary patterns with risk of scd in participants in the regards (reasons for geographic and racial differences in stroke) study cohort. |
2021-11-01 |
2023-08-13 |
human |
| David M Kent, Lester Y Leung, Yichen Zhou, Patrick H Luetmer, David F Kallmes, Jason Nelson, Sunyang Fu, Chengyi Zheng, Hongfang Liu, Wansu Che. Association of Silent Cerebrovascular Disease Identified Using Natural Language Processing and Future Ischemic Stroke. Neurology. vol 97. issue 13. 2021-10-29. PMID:34376505. |
we aimed to estimate the incidence of and risk increase in future stroke in patients with incidentally discovered scd. |
2021-10-29 |
2023-08-13 |
Not clear |
| Albraa Abulhamail, Saif Selati, Rakan Alasqa. The association between obstructive sleep apnea and stroke in sickle-cell disease children. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2021-10-29. PMID:34713338. |
the prevalence of stroke in scd patients was reported to be around 4%; however, the pediatric category was among the higher risk group for stroke compared to young and middle age adults. |
2021-10-29 |
2023-08-13 |
Not clear |
| Albraa Abulhamail, Saif Selati, Rakan Alasqa. The association between obstructive sleep apnea and stroke in sickle-cell disease children. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2021-10-29. PMID:34713338. |
the objective of this study is to calculate the prevalence of stroke in children with scd with and without obstructive sleep apnea. |
2021-10-29 |
2023-08-13 |
Not clear |
| Jessica Venugopal, Jintao Wang, Jalal Mawri, Chiao Guo, Daniel Eitzma. Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease. Haematologica. vol 106. issue 9. 2021-10-27. PMID:32817286. |
the causal role of inflammatory pathways in stroke associated with scd is unclear. |
2021-10-27 |
2023-08-13 |
mouse |
| Jessica Venugopal, Jintao Wang, Jalal Mawri, Chiao Guo, Daniel Eitzma. Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease. Haematologica. vol 106. issue 9. 2021-10-27. PMID:32817286. |
deficiency of non-hematopoietic il-1r or treatment with an il-1r antagonist is sufficient to confer protection against the increased stroke size associated with scd. |
2021-10-27 |
2023-08-13 |
mouse |
| Kaitlin Strumph, Michael Hafeman, Saritha Ranabothu, William Gomes, Steven Benitez, Frederick Kaskel, Deepa Manwani, Joseph Mahgerefte. Nocturnal hypertension associated with stroke and silent cerebral infarcts in children with sickle cell disease. Pediatric blood & cancer. vol 68. issue 5. 2021-10-14. PMID:33405393. |
strokes and silent cerebral infarcts (scis) lead to significant morbidity and mortality in children with sickle cell disease (scd). |
2021-10-14 |
2023-08-13 |
Not clear |
| Kaitlin Strumph, Michael Hafeman, Saritha Ranabothu, William Gomes, Steven Benitez, Frederick Kaskel, Deepa Manwani, Joseph Mahgerefte. Nocturnal hypertension associated with stroke and silent cerebral infarcts in children with sickle cell disease. Pediatric blood & cancer. vol 68. issue 5. 2021-10-14. PMID:33405393. |
higher systolic blood pressures increase risk for stroke and scis; however, patients with scd often have lower clinic blood pressures than the general population. |
2021-10-14 |
2023-08-13 |
Not clear |
| Deborah Friedman, Allen J Dozor, Jordan Milner, Marise D'Souza, Julie-An Talano, Theodore B Moore, Shalini Shenoy, Qiuhu Shi, Mark C Walters, Elliott Vichinsky, Susan K Parsons, Suzanne Braniecki, Chitti R Moorthy, Janet Ayello, Allyson Flower, Erin Morris, Harshini Mahanti, Sandra Fabricatore, Liana Klejmont, Carmella van de Ven, Lee Ann Baxter-Lowe, Mitchell S Cair. Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation. Bone marrow transplantation. vol 56. issue 9. 2021-10-13. PMID:33958740. |
in this prospective multicenter phase ii trial of myeloimmunoablative conditioning followed by haploidentical stem cell transplantation in children with high-risk scd, 19 patients, 2.0-21.0 years of age, were enrolled with one or more of the following: history of (1) overt stroke; (2) silent stroke; (3) elevated transcranial doppler velocity; (4) multiple vaso-occlusive crises; and/or (5) two or more acute chest syndromes and received haploidentical transplants from 18 parental donors. |
2021-10-13 |
2023-08-13 |
Not clear |
| Luis E F Almeida, Li Wang, Sayuri Kamimura, Patricia M Zerfas, Meghann L Smith, Osorio L Abath Neto, Ticiana Vale, Martha M Quezado, Iren Horkayne-Szakaly, Paul Wakim, Zenaide M N Quezad. Locomotor mal-performance and gait adaptability deficits in sickle cell mice are associated with vascular and white matter abnormalities and oxidative stress in cerebellum. Brain research. vol 1746. 2021-10-01. PMID:32533970. |
patients with sickle cell disease (scd) can develop strokes and as a result, present neurologic and neurocognitive deficits. |
2021-10-01 |
2023-08-13 |
mouse |
| Tanmay Mathur, Jonathan M Flanagan, Abhishek Jai. Tripartite collaboration of blood-derived endothelial cells, next generation RNA sequencing and bioengineered vessel-chip may distinguish vasculopathy and thrombosis among sickle cell disease patients. Bioengineering & translational medicine. vol 6. issue 3. 2021-10-01. PMID:34589594. |
in particular, it is currently difficult to predict the adverse outcomes within patients with scd, such as, vasculopathy, thrombosis, and stroke. |
2021-10-01 |
2023-08-13 |
Not clear |