| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marianne E McPherson, Alan R Anderson, Ann E Haight, Paula Jessup, Marta-Inés Castillejo, Christopher D Hillyer, Cassandra D Josephso. Transfusion management of sickle cell patients during bone marrow transplantation with matched sibling donor. Transfusion. vol 49. issue 9. 2009-09-23. PMID:19453984. |
sickle cell disease (scd) patients have unique transfusion considerations during bone marrow transplantation (bmt), including prophylaxis against stroke and alloimmunization. |
2009-09-23 |
2023-08-12 |
Not clear |
| Michael R Debaun, Joshua J Fiel. Limitations of clinical trials in sickle cell disease: a case study of the Multi-center Study of Hydroxyurea (MSH) trial and the Stroke Prevention (STOP) trial. Hematology. American Society of Hematology. Education Program. 2009-07-14. PMID:18024668. |
in the past two decades, two landmark randomized controlled trials (rct) have been completed among individuals with sickle cell disease (scd), the multi-center study of hydroxyurea (msh) trial and the stroke prevention (stop) trial. |
2009-07-14 |
2023-08-12 |
human |
| Valentine Brousse, Lucie Hertz-Pannier, Yann Consigny, Jean-Louis Bresson, Robert Girot, Elsa Mirre, Gérard Lenoir, Mariane de Montalember. Does regular blood transfusion prevent progression of cerebrovascular lesions in children with sickle cell disease? Annals of hematology. vol 88. issue 8. 2009-07-07. PMID:19107481. |
a retrospective study was conducted to assess changes in cerebrovascular lesions, as assessed by magnetic resonance (mr) imaging and angiography in 18 children with sickle cell disease (scd) receiving optimised chronic transfusions for primary stroke prevention (abnormal transcranial doppler flow, nine patients, median follow-up 14.3 months (range, 7.9-48.9)) or secondary stroke prevention (nine patients, median follow-up 59.6 months (range, 11.0-127.9)). |
2009-07-07 |
2023-08-12 |
Not clear |
| Valentine Brousse, Lucie Hertz-Pannier, Yann Consigny, Jean-Louis Bresson, Robert Girot, Elsa Mirre, Gérard Lenoir, Mariane de Montalember. Does regular blood transfusion prevent progression of cerebrovascular lesions in children with sickle cell disease? Annals of hematology. vol 88. issue 8. 2009-07-07. PMID:19107481. |
optimised transfusion therapy does not prevent progression of cerebral vasculopathy in scd children with a history of stroke. |
2009-07-07 |
2023-08-12 |
Not clear |
| Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
sickle cell disease (scd) is the most frequent cause of stroke during infancy, and stroke is the most serious complication of scd in children. |
2009-06-26 |
2023-08-12 |
Not clear |
| Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
sludge-induced distal vasculopathy explains 25% of strokes in scd, while proximal vasculopathy is responsible for 75% of cases. |
2009-06-26 |
2023-08-12 |
Not clear |
| Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
this approach has been adopted in our institution, based on a cohort of scd newborns screened at birth: the risk of stroke was reduced from the expected 11% to less than 2% at 18 years. |
2009-06-26 |
2023-08-12 |
Not clear |
| J Armstrong-Wells, B Grimes, S Sidney, D Kronish, S C Shiboski, R J Adams, H J Fullerto. Utilization of TCD screening for primary stroke prevention in children with sickle cell disease. Neurology. vol 72. issue 15. 2009-05-01. PMID:19365052. |
in 1998, the stroke prevention trial in sickle cell anemia showed a >90% reduction in stroke rates after blood transfusion therapy in children with sickle cell disease (scd) identified as high risk with transcranial doppler ultrasonography (tcd) screening. |
2009-05-01 |
2023-08-12 |
Not clear |
| Yu-Sok Kim, Erfan Nur, Eduard J van Beers, Jasper Truijen, Shyrin C A T Davis, Bart J Biemond, Johannes J van Lieshou. Dynamic cerebral autoregulation in homozygous Sickle cell disease. Stroke. vol 40. issue 3. 2009-03-20. PMID:19150866. |
sickle cell disease (scd) is associated with cerebral hyperperfusion and an increased risk of stroke. |
2009-03-20 |
2023-08-12 |
Not clear |
| Cynthia L Price, Michael T Johnson, Terianne Lindsay, Douglas Dalton, A R Watkins, Michael R DeBau. The Sickle Cell Sabbath: a community program increases first-time blood donors in the African American faith community. Transfusion. vol 49. issue 3. 2009-03-16. PMID:19040492. |
blood transfusion therapy is an established treatment for primary and secondary prevention of strokes in children with sickle cell disease (scd), a disease that predominantly affects african americans. |
2009-03-16 |
2023-08-12 |
Not clear |
| Jean L Raphael, Priya B Shetty, Hao Liu, Donald H Mahoney, Brigitta U Muelle. A critical assessment of transcranial doppler screening rates in a large pediatric sickle cell center: opportunities to improve healthcare quality. Pediatric blood & cancer. vol 51. issue 5. 2008-10-07. PMID:18623200. |
transcranial doppler ultrasound (tcd) has been demonstrated to be a powerful predictor of stroke risk due to sickle cell disease (scd) in pediatric populations. |
2008-10-07 |
2023-08-12 |
Not clear |
| Jeffrey I Gold, Caroline B Johnson, Marsha J Treadwell, Nitu Hans, Elliott Vichinsk. Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569843. |
sickle cell disease (scd) is associated with increased risk of stroke and cognitive impairment. |
2008-08-07 |
2023-08-12 |
Not clear |
| Jeffrey I Gold, Caroline B Johnson, Marsha J Treadwell, Nitu Hans, Elliott Vichinsk. Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569843. |
based on mri analysis, 27% of patients with scd had experienced a stroke and 13% a silent infarct. |
2008-08-07 |
2023-08-12 |
Not clear |
| Michael Wolf, Carla Cangemi, Richard Drachtman, Margaret Masterso. Primary hemorrhagic stroke in a 12-year-old female with sickle cell disease and normal transcranial Doppler. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569847. |
stroke is a well-known complication of sickle cell disease (scd). |
2008-08-07 |
2023-08-12 |
Not clear |
| Swee Lay Thei. Genetic modifiers of the beta-haemoglobinopathies. British journal of haematology. vol 141. issue 3. 2008-06-27. PMID:18410570. |
since some of the complications, such as overt stroke in scd, are relatively rare events, intermediate end-points that contribute to the phenotype, such as transcranial doppler velocity (a major predictor of stroke in scd), could be integrated within the genetic analysis. |
2008-06-27 |
2023-08-12 |
Not clear |
| Cheryl A Hillery, Julie A Panepint. Pathophysiology of stroke in sickle cell disease. Microcirculation (New York, N.Y. : 1994). vol 11. issue 2. 2008-06-03. PMID:15280092. |
stroke affects both motor and cognitive function in patients with sickle cell disease (scd). |
2008-06-03 |
2023-08-12 |
Not clear |
| Cheryl A Hillery, Julie A Panepint. Pathophysiology of stroke in sickle cell disease. Microcirculation (New York, N.Y. : 1994). vol 11. issue 2. 2008-06-03. PMID:15280092. |
while the natural history of stroke in scd is well described, the pathophysiology remains poorly understood and probably varies with the site of vascular injury. |
2008-06-03 |
2023-08-12 |
Not clear |
| Allison A King, Michael R DeBaun, Desiree A Whit. Need for cognitive rehabilitation for children with sickle cell disease and strokes. Expert review of neurotherapeutics. vol 8. issue 2. 2008-04-10. PMID:18271713. |
stroke is a significant cause of morbidity among children with sickle cell disease (scd). |
2008-04-10 |
2023-08-12 |
Not clear |
| Allison A King, Michael R DeBaun, Desiree A Whit. Need for cognitive rehabilitation for children with sickle cell disease and strokes. Expert review of neurotherapeutics. vol 8. issue 2. 2008-04-10. PMID:18271713. |
ongoing studies are designed to improve the cognitive impairment for children with scd and stroke. |
2008-04-10 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
young children with scd are at a very high risk of stroke. |
2008-01-24 |
2023-08-12 |
Not clear |