| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruth Yamawaki, Khushdev Thind, Paul S Buckmaste. Blockade of excitatory synaptogenesis with proximal dendrites of dentate granule cells following rapamycin treatment in a mouse model of temporal lobe epilepsy. The Journal of comparative neurology. vol 523. issue 2. 2015-08-04. PMID:25234294. |
to test this possibility stereological electron microscopy was used to estimate the numbers of excitatory synapses in the inner molecular layer per hippocampus in pilocarpine-treated control mice, in mice 5 days after pilocarpine-induced status epilepticus, and after status epilepticus and daily treatment beginning 24 hours later with rapamycin or vehicle for 2 months. |
2015-08-04 |
2023-08-13 |
mouse |
| Vinícius Rafael Funck, Leandro Rodrigo Ribeiro, Letícia Meier Pereira, Clarissa Vasconcelos de Oliveira, Jéssica Grigoletto, Michele Rechia Fighera, Luiz Fernando Freire Royes, Ana Flávia Furian, Mauro Schneider Oliveir. Long-term decrease in Na+,K+-ATPase activity after pilocarpine-induced status epilepticus is associated with nitration of its alpha subunit. Epilepsy research. vol 108. issue 10. 2015-08-04. PMID:25311690. |
activity of na(+),k(+)-atpase decreased in the hippocampus of c57bl/6 mice 60 days after pilocarpine-induced status epilepticus (se). |
2015-08-04 |
2023-08-13 |
mouse |
| Elzbieta Wiernasz, Aleksandra Kaliszewska, Wojciech Brutkowski, Joanna Bednarczyk, Malgorzata Gorniak, Beata Kaza, Katarzyna Lukasiu. Ttyh1 protein is expressed in glia in vitro and shows elevated expression in activated astrocytes following status epilepticus. Neurochemical research. vol 39. issue 12. 2015-08-04. PMID:25316497. |
moreover, using double immunofluorescence, we show ttyh1 protein expression in activated astrocytes in the hippocampus following amygdala stimulation-induced status epilepticus. |
2015-08-04 |
2023-08-13 |
Not clear |
| Rod C Scot. Consequences of febrile seizures in childhood. Current opinion in pediatrics. vol 26. issue 6. 2015-07-22. PMID:25304962. |
there is a long-standing hypothesis that febrile status epilepticus (fse) can cause brain injury, particularly to the hippocampus. |
2015-07-22 |
2023-08-13 |
Not clear |
| Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
here, we used a rat model of pilocarpine-induced status epilepticus (se) to investigate hif-1α expression and apoptosis in the hippocampus, and to explore their relationship during epileptogenesis. |
2015-07-09 |
2023-08-13 |
rat |
| Patrizia Ambrogini, Andrea Minelli, Claudia Galati, Michele Betti, Davide Lattanzi, Silvia Ciffolilli, Marta Piroddi, Francesco Galli, Riccardo Cuppin. Post-seizure α-tocopherol treatment decreases neuroinflammation and neuronal degeneration induced by status epilepticus in rat hippocampus. Molecular neurobiology. vol 50. issue 1. 2015-06-10. PMID:24488645. |
post-seizure α-tocopherol treatment decreases neuroinflammation and neuronal degeneration induced by status epilepticus in rat hippocampus. |
2015-06-10 |
2023-08-12 |
rat |
| Patrizia Ambrogini, Andrea Minelli, Claudia Galati, Michele Betti, Davide Lattanzi, Silvia Ciffolilli, Marta Piroddi, Francesco Galli, Riccardo Cuppin. Post-seizure α-tocopherol treatment decreases neuroinflammation and neuronal degeneration induced by status epilepticus in rat hippocampus. Molecular neurobiology. vol 50. issue 1. 2015-06-10. PMID:24488645. |
we previously showed that α-t oral supplementation before inducing status epilepticus, markedly reduces astrocytic and microglial activation, neuronal cell death and oxidative stress in the hippocampus, as observed 4 days after seizure. |
2015-06-10 |
2023-08-12 |
rat |
| H L Grabenstatter, J Carlsen, Y H Raol, T Yang, D Hund, Y Cruz Del Angel, A M White, M I Gonzalez, F M Longo, S J Russek, A R Brooks-Kaya. Acute administration of the small-molecule p75(NTR) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticus. Journal of neuroscience research. vol 92. issue 10. 2015-05-11. PMID:24801281. |
acute administration of the small-molecule p75(ntr) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticus. |
2015-05-11 |
2023-08-13 |
rat |
| Asheebo Rojas, Paoula Gueorguieva, Nadia Lelutiu, Yi Quan, Renee Shaw, Raymond Dingledin. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiology of disease. vol 70. 2015-04-21. PMID:24952362. |
ep1-ko mice that did experience typical status epilepticus had reduced hippocampal neurodegeneration and a blunted inflammatory response. |
2015-04-21 |
2023-08-13 |
mouse |
| Asheebo Rojas, Paoula Gueorguieva, Nadia Lelutiu, Yi Quan, Renee Shaw, Raymond Dingledin. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiology of disease. vol 70. 2015-04-21. PMID:24952362. |
taken together, these results indicate that ep1 receptor activation during seizures, through a protein kinase c pathway, increases the probability of kainic acid induced status epilepticus, and independently promotes hippocampal neurodegeneration and a broad inflammatory response. |
2015-04-21 |
2023-08-13 |
mouse |
| Meng Na, Yanshu Liu, Chen Shi, Wenpeng Gao, Haitao Ge, Yu Wang, Haiyang Wang, Yu Long, Hong Shen, Changbin Shi, Zhiguo Li. Prognostic value of CA4/DG volumetry with 3T magnetic resonance imaging on postoperative outcome of epilepsy patients with dentate gyrus pathology. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25085233. |
pathological hallmarks in hippocampal dentate gyrus (dg), including granule cell loss (gcl) and granule cell dispersion (gcd), are known to be closely related to the status epilepticus and spontaneous seizure. |
2015-04-20 |
2023-08-13 |
Not clear |
| Michele Juliane Vieira, Sandra Regina Perosa, Gustavo Adolfo Argaãaraz, José Antônio Silva, Esper Abrão Cavalheiro, Maria da Graça Naffah-Mazzacoratt. Indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus. Clinics (Sao Paulo, Brazil). vol 69. issue 9. 2015-04-08. PMID:25318094. |
indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus. |
2015-04-08 |
2023-08-13 |
rat |
| Weihua Yu, Dan Chen, Zhihua Wang, Chunlei Zhou, Jing Luo, Yali Xu, Lan Shen, Huan Yin, Shuxin Tao, Zheng Xiao, Fei Xiao, Yang Lü, Xuefeng Wan. Time-dependent decrease of clusterin as a potential cerebrospinal fluid biomarker for drug-resistant epilepsy. Journal of molecular neuroscience : MN. vol 54. issue 1. 2015-04-01. PMID:24488574. |
moreover, alteration of clu was detected in the rat hippocampus over time after pilocarpine-induced status epilepticus (se). |
2015-04-01 |
2023-08-12 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
status epilepticus in the adult brain invariably causes an increase in hippocampal neurogenesis and the appearance of ectopic cells and this has been implicated as a causal factor in epileptogenesis. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
the effect of status epilepticus on neurogenesis in the developing brain is less well characterized and models of early-life seizures typically do not reproduce the hippocampal damage common to human mesial temporal sclerosis. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
we recently reported that evoking status epilepticus by intra-amygdala microinjection of kainic acid in post-natal (p) day 10 rats caused substantial acute neuronal death within the ipsilateral hippocampus and rats later developed unilateral hippocampal sclerosis and spontaneous recurrent seizures. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
protein levels of several markers of neurogenesis including polysialic acid neural cell adhesion molecule, neurod and doublecortin were reduced in the hippocampus three days after status epilepticus in p10 rats. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
pulse-chase experiments using thymidine analogues suggested there was a reduction in new neurons at 72 h after status epilepticus in p10 rats, whereas numbers of new neurons labelled in epileptic rats at p55 with hippocampal sclerosis were similar to controls. |
2015-03-10 |
2023-08-13 |
human |
| Mark Dunleavy, Clara K Schindler, Sachiko Shinoda, Shane Crilly, David C Henshal. Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus. International journal of physiology, pathophysiology and pharmacology. vol 6. issue 4. 2015-03-10. PMID:25755841. |
the present study suggests that status epilepticus in the immature brain suppresses neurogenesis but the neurogenic potential is retained in animals that later develop hippocampal sclerosis. |
2015-03-10 |
2023-08-13 |
human |