Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ajay X Thomas, Yasmin Cruz Del Angel, Marco I Gonzalez, Andrew J Carrel, Jessica Carlsen, Philip M Lam, Barbara L Hempstead, Shelley J Russek, Amy R Brooks-Kaya. Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery. eNeuro. vol 3. issue 1. 2016-10-27. PMID:27057559. |
brain-derived neurotrophic factor (bdnf) levels are elevated after status epilepticus (se), leading to activation of multiple signaling pathways, including the janus kinase/signal transducer and activator of transcription pathway that mediates a decrease in gabaa receptor α1 subunits in the hippocampus (lund et al., 2008). |
2016-10-27 |
2023-08-13 |
mouse |
Hua Yu Sun, Howard P Goodki. The pervasive reduction of GABA-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus. Epilepsy research. vol 119. 2016-09-30. PMID:26656782. |
the pervasive reduction of gaba-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus. |
2016-09-30 |
2023-08-13 |
Not clear |
Hua Yu Sun, Howard P Goodki. The pervasive reduction of GABA-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus. Epilepsy research. vol 119. 2016-09-30. PMID:26656782. |
the goal of this study was to determine whether there are region-specific or time-dependent changes in gaba-mediated synaptic inhibition of principal neurons in the hippocampus during in vivo status epilepticus. |
2016-09-30 |
2023-08-13 |
Not clear |
Hua Yu Sun, Howard P Goodki. The pervasive reduction of GABA-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus. Epilepsy research. vol 119. 2016-09-30. PMID:26656782. |
standard whole cell patch clamp electrophysiological techniques were used to characterize miniature inhibitory postsynaptic currents (mipscs) in recordings from the principal neurons (pns) of the dentate gyrus, ca1, and ca3 in acutely-obtained hippocampal slices from control and lithium/pilocarpine-induced status epilepticus(se)-treated animals. |
2016-09-30 |
2023-08-13 |
Not clear |
Anna Karynna Alves de Alencar Rocha, Eliangela de Lima, Fernanda Gaspar do Amaral, Rafael Peres, José Cipolla-Neto, Débora Amad. Pilocarpine-induced epilepsy alters the expression and daily variation of the nuclear receptor RORα in the hippocampus of rats. Epilepsy & behavior : E&B. vol 55. 2016-09-26. PMID:26731717. |
our results indicate that the status epilepticus induced by pilocarpine is able to change the expression and daily variation of rorα in the rat hippocampal area during the acute and silent phases. |
2016-09-26 |
2023-08-13 |
rat |
Tianqing Xiong, Jiamei Liu, Gaoyue Dai, Yuan Hou, Baihong Tan, Yanfeng Zhang, Shulei Li, Yan Song, Haiyan Liu, Yongnan Li, Yanchao L. The progressive changes of filamentous actin cytoskeleton in the hippocampal neurons after pilocarpine-induced status epilepticus. Epilepsy research. vol 118. 2016-09-19. PMID:26600371. |
the progressive changes of filamentous actin cytoskeleton in the hippocampal neurons after pilocarpine-induced status epilepticus. |
2016-09-19 |
2023-08-13 |
mouse |
Tianqing Xiong, Jiamei Liu, Gaoyue Dai, Yuan Hou, Baihong Tan, Yanfeng Zhang, Shulei Li, Yan Song, Haiyan Liu, Yongnan Li, Yanchao L. The progressive changes of filamentous actin cytoskeleton in the hippocampal neurons after pilocarpine-induced status epilepticus. Epilepsy research. vol 118. 2016-09-19. PMID:26600371. |
in a previous study, we reported a persistent reduction of f-actin puncta but a compensating increase in puncta size in the mouse hippocampus at 2 months after pilocarpine-induced status epilepticus (epilepsy res. |
2016-09-19 |
2023-08-13 |
mouse |
Cesar E Santana-Gomez, David Alcantara-Gonzalez, Hiram Luna-Munguia, Ivette Banuelos-Cabrera, Victor Magdaleno-Madrigal, Michael Tamayo, Luisa L Rocha, Walter G Besi. Transcranial focal electrical stimulation reduces seizure activity and hippocampal glutamate release during status epilepticus. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2016-09-02. PMID:26737802. |
transcranial focal electrical stimulation reduces seizure activity and hippocampal glutamate release during status epilepticus. |
2016-09-02 |
2023-08-13 |
rat |
Jennifer N Pearson, Shane Rowley, Li-Ping Liang, Andrew M White, Brian J Day, Manisha Pate. Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy. Neurobiology of disease. vol 82. 2016-08-24. PMID:26184893. |
using a synthetic catalytic antioxidant, we show that pharmacological removal of reactive oxygen species (ros) prevents 1) oxidative stress, 2) deficits in mitochondrial oxygen consumption rates, 3) hippocampal neuronal loss and 4) cognitive dysfunction without altering the intensity of the initial status epilepticus (se) or epilepsy development in a rat model of se-induced tle. |
2016-08-24 |
2023-08-13 |
rat |
Chiara Falcicchia, Pascal Trempat, Anna Binaschi, Coline Perrier-Biollay, Paolo Roncon, Marie Soukupova, Hervé Berthommé, Michele Simonat. Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors. PloS one. vol 11. issue 3. 2016-08-03. PMID:26954758. |
however, only the antisense strategy was effective in vivo, after inoculation in the hippocampus in a model of status epilepticus in which bdnf mrna levels are strongly increased. |
2016-08-03 |
2023-08-13 |
Not clear |
Ah-Reum Ko, Tae-Cheon Kan. Mannitol induces selective astroglial death in the CA1 region of the rat hippocampus following status epilepticus. BMB reports. vol 48. issue 9. 2016-07-07. PMID:25703536. |
mannitol induces selective astroglial death in the ca1 region of the rat hippocampus following status epilepticus. |
2016-07-07 |
2023-08-13 |
rat |
Walid Alsharafi, Bo Xia. Dynamic Expression of MicroRNAs (183, 135a, 125b, 128, 30c and 27a) in the Rat Pilocarpine Model and Temporal Lobe Epilepsy Patients. CNS & neurological disorders drug targets. vol 14. issue 8. 2016-07-07. PMID:25801837. |
quantitative polymerase chain reaction was performed on rat hippocampus 2 hours, 3 weeks and 2 months following pilocarpine-induced status epilepticus, representing the acute, latent, and chronic phases, respectively. |
2016-07-07 |
2023-08-13 |
rat |
A-R Ko, J Y Kim, H-W Hyun, J-E Ki. Endoplasmic reticulum (ER) stress protein responses in relation to spatio-temporal dynamics of astroglial responses to status epilepticus in rats. Neuroscience. vol 307. 2016-07-06. PMID:26335380. |
in the present study, we investigated whether endoplasmic reticulum (er) stress is associated with neuronal- and astroglial-death in the hippocampus using licl-pilocarpine-induced status epilepticus (se) rat model. |
2016-07-06 |
2023-08-13 |
rat |
Beatriz O Amorim, Luciene Covolan, Elenn Ferreira, José Geraldo Brito, Diego P Nunes, David G de Morais, José N Nobrega, Antonio M Rodrigues, Antonio Carlos G deAlmeida, Clement Haman. Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats. Journal of neuroinflammation. vol 12. 2016-06-21. PMID:26337974. |
status epilepticus (se) is a severe condition that may lead to hippocampal cell loss and epileptogenesis. |
2016-06-21 |
2023-08-13 |
rat |
Chong-Hyun Ki. Cav3.1 T-type calcium channel modulates the epileptogenicity of hippocampal seizures in the kainic acid-induced temporal lobe epilepsy model. Brain research. vol 1622. 2016-06-02. PMID:26111648. |
during the acute status epilepticus (se) period, both the duration and the frequency of hippocampal seizures were significantly reduced and increased, respectively, in αlg ko mice compared to those of wild type mice. |
2016-06-02 |
2023-08-13 |
mouse |
Lei Xiang, Yanping Ren, Hao Cai, Wen Zhao, Yijun Son. MicroRNA-132 aggravates epileptiform discharges via suppression of BDNF/TrkB signaling in cultured hippocampal neurons. Brain research. vol 1622. 2016-06-01. PMID:26168887. |
in the present study, we found a dramatic upregulation of mir-132 and bdnf mrna in the hippocampal neuronal culture model of status epilepticus (se) obtained by mg(2+)-free treatment. |
2016-06-01 |
2023-08-13 |
Not clear |
Rod C Scot. What are the effects of prolonged seizures in the brain? Epileptic disorders : international epilepsy journal with videotape. vol 16 Spec No 1. 2016-05-31. PMID:25323416. |
there is evidence from animal models and prospective human studies that the hippocampus may be injured during febrile status epilepticus although this pathophysiological sequence remains uncommon. |
2016-05-31 |
2023-08-13 |
human |
Cui Wang, Nanchang Xie, Yunlong Wang, Yulin Li, Xinjie Ge, Menglu Wan. Role of the Mitochondrial Calcium Uniporter in Rat Hippocampal Neuronal Death After Pilocarpine-Induced Status Epilepticus. Neurochemical research. vol 40. issue 8. 2016-05-27. PMID:26148531. |
role of the mitochondrial calcium uniporter in rat hippocampal neuronal death after pilocarpine-induced status epilepticus. |
2016-05-27 |
2023-08-13 |
rat |
Cui Wang, Nanchang Xie, Yunlong Wang, Yulin Li, Xinjie Ge, Menglu Wan. Role of the Mitochondrial Calcium Uniporter in Rat Hippocampal Neuronal Death After Pilocarpine-Induced Status Epilepticus. Neurochemical research. vol 40. issue 8. 2016-05-27. PMID:26148531. |
in this study, we found that the mcu inhibitor ru360 significantly attenuated neuronal death and exerted an anti-apoptotic effect on rat hippocampal neurons after pilocarpine-induced status epilepticus (se), while the mcu activator spermine increased seizure-induced neuronal death and apoptosis. |
2016-05-27 |
2023-08-13 |
rat |
Chang Zeng, Pinting Zhou, Ting Jiang, Chunyun Yuan, Yan Ma, Li Feng, Renkai Liu, Weiting Tang, Xiaoyan Long, Bo Xiao, Fafa Tia. Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25213992. |
we measured the expression of two subtypes of trpc channels, trpc3 and trpc6, in temporal lobe epileptic foci excised from patients with intractable epilepsy and in hippocampus of mice with pilocarpine-induced status epilepticus (se), an animal model of tle. |
2016-05-17 |
2023-08-13 |
mouse |