| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Chvojka, J Kudláček, K Liska, A Pant, J Gr Jefferys, P Jirusk. Dissociation Between the Epileptogenic Lesion and Primary Seizure Onset Zone in the Tetanus Toxin Model of Temporal Lobe Epilepsy. Physiological research. vol 73. issue 3. 2024-07-19. PMID:39027960. |
conventional tle models like kainate and pilocarpine hinder precise assessment of the role of individual limbic structures in tle ictogenesis due to widespread limbic damage induced by the initial status epilepticus. |
2024-07-19 |
2024-07-21 |
Not clear |
| Kristina Junghans, Megan Wyeth, Paul S Buckmaste. Rat strain differences in seizure frequency and hilar neuron loss after systemic treatment with pilocarpine. Epilepsy research. vol 204. 2024-06-16. PMID:38879905. |
at least 3 months after systemic treatment with pilocarpine to induce status epilepticus, long-evans and sprague-dawley rats were video-eeg monitored for seizures continuously for 1 month. |
2024-06-16 |
2024-06-19 |
rat |
| Hiram Luna-Munguia, Deisy Gasca-Martinez, Alejandra Garay-Cortes, Daniela Coutiño, Mirelta Regalado, Ericka de Los Rios, Paulina Villaseñor, Fernando Hidalgo-Flores, Karen Flores-Guapo, Brandon Yair Benito, Luis Conch. Selective Medial Septum Lesions in Healthy Rats Induce Longitudinal Changes in Microstructure of Limbic Regions, Behavioral Alterations, and Increased Susceptibility to Status Epilepticus. Molecular neurobiology. 2024-03-05. PMID:38443731. |
twenty-four different animals received pilocarpine to evaluate the latency and severity of the status epilepticus 2 weeks after surgery. |
2024-03-05 |
2024-03-08 |
rat |
| Grigorios Kyriatzis, Anne Bernard, Angélique Bôle, Michel Khrestchatisky, Lotfi Ferha. In the Rat Hippocampus, Pilocarpine-Induced Status Epilepticus Is Associated with Reactive Glia and Concomitant Increased Expression of CD31, PDGFRβ, and Collagen IV in Endothelial Cells and Pericytes of the Blood-Brain Barrier. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338969. |
in this work, we induced status epilepticus in rats through injection of the proconvulsant drug pilocarpine, which leads to tle. |
2024-02-10 |
2024-02-12 |
rat |
| Letícia Meier, Estevan Bruginski, Joseane Righes Marafiga, Letícia Barbieri Caus, Mayara Vendramin Pasquetti, Maria Elisa Calcagnotto, Francinete Ramos Campo. Hippocampal metabolic profile during epileptogenesis in the pilocarpine model of epilepsy. Biomedical chromatography : BMC. 2023-12-28. PMID:38154955. |
using a pilocarpine model of epilepsy, we analyzed the global metabolic profile of hippocampal extracts by untargeted metabolomics based on ultra-performance liquid chromatography-high-resolution mass spectrometry, at three time points (3 h, 1 week, and 2 weeks) after status epilepticus (se) induction. |
2023-12-28 |
2023-12-31 |
Not clear |
| Fang Zheng, Kevin D Phelan, U Thaung Shw. Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice. Neurology international. vol 15. issue 4. 2023-12-22. PMID:38132974. |
in this study, we utilized electroencephalography (eeg) recording and spectral analysis to assess the role of trpc1/4 channels in the pilocarpine model of status epilepticus (se). |
2023-12-22 |
2023-12-24 |
mouse |
| Jiandong Yu, Vijayalakshmi Santhakuma. Electrical Coupling between Parvalbumin Basket Cells is Reduced after Experimental Status Epilepticus. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808695. |
using a pilocarpine induced status epilepticus (se) model of acquired temporal lobe epilepsy in rat, this study examined changes in electrical coupling between pv-ins in the hippocampal dentate gyrus one week after se. |
2023-10-09 |
2023-10-15 |
human |
| Xinyu Zhang, Yanjun Yi, Li Cheng, Hengsheng Chen, Yue H. Dynamic effects of miR-20a-5p on hippocampal ripple energy after status epilepticus in rats. Experimental brain research. 2023-07-18. PMID:37464223. |
a lithium pilocarpine (licl-pilo)-induced rat model of status epilepticus (se) was established, and the rats were divided into the normal control (control, ctl), epileptic control (pilo), valproic acid (vpa + pilo), mir-20a-5p overexpression lentivirus vector (mir + pilo), sponges blocking lentivirus vector (sponges + pilo), and scramble sequence negative control (scramble + pilo) groups (n = 6). |
2023-07-18 |
2023-08-14 |
rat |
| Ahmad Tarmizi Che Ha. The Applications of the Pilocarpine Animal Model of Status Epilepticus: 40 Years of Progress (1983-2023). Behavioural brain research. 2023-06-22. PMID:37348654. |
the applications of the pilocarpine animal model of status epilepticus: 40 years of progress (1983-2023). |
2023-06-22 |
2023-08-14 |
Not clear |
| Ahmad Tarmizi Che Ha. The Applications of the Pilocarpine Animal Model of Status Epilepticus: 40 Years of Progress (1983-2023). Behavioural brain research. 2023-06-22. PMID:37348654. |
in particular, the chemically induced pilocarpine animal model of status epilepticus is a reliable choice which has evolved for 40 years from its initial discovery back in 1983. |
2023-06-22 |
2023-08-14 |
Not clear |
| F A Concepcion, N A Ekstrom, M N Khan, O O Estes, N P Poolo. Progressive Dysregulation of Tau Phosphorylation in an Animal Model of Temporal Lobe Epilepsy. Neuroscience. 2023-05-04. PMID:37142182. |
here, tau expression and phosphorylation at three canonical loci known to be hyperphosphorylated in ad (s202/t205, t181, and t231) were studied in the rat pilocarpine status epilepticus (se) model of temporal lobe epilepsy (tle). |
2023-05-04 |
2023-08-14 |
human |
| Maxime Lévesque, Siyan Wang, Anežka D B Macey-Dare, Pariya Salami, Massimo Avol. Evolution of interictal activity in models of mesial temporal lobe epilepsy. Neurobiology of disease. 2023-03-12. PMID:36907521. |
this period, which is termed "latent", has been studied in rodent models of mtle in which spontaneous seizures start to occur following an initial insult (most often a status epilepticus induced by convulsive drugs such as kainic acid or pilocarpine) and may mirror epileptogenesis, i.e., the process leading the brain to develop an enduring predisposition to seizure generation. |
2023-03-12 |
2023-08-14 |
Not clear |
| Luiz E C Santos, Antônio-Carlos G Almeida, Sílvia C B Silva, Antônio M Rodrigues, Samyra G Cecílio, Carla A Scorza, Josef Finsterer, Marcelo Moret, Fulvio A Scorz. The amygdala lesioning due to status epilepticus - Changes in mechanisms controlling chloride homeostasis. Clinics (Sao Paulo, Brazil). vol 78. 2023-02-12. PMID:36774732. |
in this study, the authors aimed to investigate if these changes are present in the amygdala after induction of status epilepticus with pilocarpine, which may be directly correlated with sudden unexpected death in epilepsy (sudep). |
2023-02-12 |
2023-08-14 |
Not clear |
| Qiong Wu, Hua Wang, Xueyan Liu, Yajuan Zhao, Peng S. Microglial activation and over pruning involved in developmental epilepsy. Journal of neuropathology and experimental neurology. 2022-12-01. PMID:36453895. |
to understand the potential role of microglia in synaptic pruning following status epilepticus (se), we examined the time course of expression of iba-1, and immune and neuroinflammatory regulators, including cd86, cd206, and cx3cr1, and tlr4/nf-κb after se induced by pilocarpine in rats. |
2022-12-01 |
2023-08-14 |
rat |
| Michaela Shishmanova-Doseva, Katerina Georgieva, Yordanka Uzunova, Lyubka Ioanidu, Milena Atanasova, Zlatina Nenchovska, Jana Tchekalarov. Pre- and Post-Endurance Training Mitigates the Rat Pilocarpine-Induced Status Epilepticus and Epileptogenesis-Associated Deleterious Consequences. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36361978. |
the objective of the current study was to investigate the effects of endurance training, applied before and after pilocarpine (pilo) administration, on status epilepticus (se) severity, and its relation to epileptogenesis deleterious consequences during the chronic epileptic phase. |
2022-11-11 |
2023-08-14 |
human |
| Amanda Larissa Dias Pacheco, Igor Santana de Melo, Maisa de Araujo Costa, Mariah Morais Celestino Amaral, Nívea Karla de Gusmão Taveiros Silva, Yngrid Mickaelli Oliveira Santos, Daniel Leite Góes Gitaí, Marcelo Duzzioni, Alexandre Urban Borbely, Robinson Sabino Silva, Ana Luiza Ferreira Donatti, Luisa Mestriner, Carlos Alessandro Fuzo, Richard D Cummings, Norberto Garcia-Cairasco, Marcelo Dias-Baruffi, Olagide Wagner de Castr. Neuroprotective Effect of Exogenous Galectin-1 in Status Epilepticus. Molecular neurobiology. 2022-09-28. PMID:36171480. |
intrahippocampal pilocarpine microinjection (h-pilo) induces status epilepticus (se) that can lead to spontaneous recurrent seizures (srs) and neurodegeneration in rodents. |
2022-09-28 |
2023-08-14 |
rat |
| Michaela Shishmanova-Doseva, Dimitrinka Atanasova, Lyubka Ioanidu, Yordanka Uzunova, Milena Atanasova, Lyudmil Peychev, Jana Tchekalarov. The anticonvulsant effect of chronic treatment with topiramate after pilocarpine-induced status epilepticus is accompanied by a suppression of comorbid behavioral impairments and robust neuroprotection in limbic regions in rats. Epilepsy & behavior : E&B. vol 134. 2022-07-06. PMID:35792414. |
was administered 3 h after the pilocarpine (pilo)-induced status epilepticus (se) and continued for up to 12 weeks in wistar rats. |
2022-07-06 |
2023-08-14 |
rat |
| Efrat Shavit-Stein, Shani Berkowitz, Tal Davidy, Uri Fennig, Shani Guly Gofrit, Amir Dori, Nicola Maggi. Modulation of the Thrombin Pathway Restores LTP in a Pilocarpine Mice Model of Status Epilepticus. Frontiers in cellular neuroscience. vol 16. 2022-06-10. PMID:35685989. |
modulation of the thrombin pathway restores ltp in a pilocarpine mice model of status epilepticus. |
2022-06-10 |
2023-08-14 |
mouse |
| Xiangzhen Tong, Zizhu Zhang, Jianping Zhu, Shuji Li, Shaogang Qu, Bing Qin, Yanwu Guo, Rongqing Che. A Comparison of Epileptogenic Effect of Status Epilepticus Treated With Diazepam, Midazolam, and Pentobarbital in the Mouse Pilocarpine Model of Epilepsy. Frontiers in neurology. vol 13. 2022-06-07. PMID:35669869. |
a comparison of epileptogenic effect of status epilepticus treated with diazepam, midazolam, and pentobarbital in the mouse pilocarpine model of epilepsy. |
2022-06-07 |
2023-08-14 |
mouse |
| Jinghui Zhang, Nana Qiao, Jiwen Wang, Baomin L. Nuclear translocation of GluA2/ GAPDH promotes neurotoxicity after pilocarpine-induced epilepsy. Epilepsy research. vol 183. 2022-05-31. PMID:35636277. |
in this study, induced status epilepticus (se) in rats by the systemic administration of pilocarpine, collected hippocampal tissues at different time points after se, and assessed the relationship between glua2/gapdh coupling and neuronal apoptosis in se rats. |
2022-05-31 |
2023-08-13 |
rat |