| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haoyang Huang, Nicholas Toker, Eliza Burr, Jeff Okoro, Maia Moog, Casey Hearing, Sarita Lagalwa. Intercellular Propagation and Aggregate Seeding of Mutant Ataxin-1. Journal of molecular neuroscience : MN. 2021-11-26. PMID:34826062. |
propagation of oligomeric-structured polyglutamine-expanded ataxin-1 (atxn1[154q]) has been reported in the cerebellum of a spinocerebellar ataxia type 1 (sca1) knock-in mouse to correlate with disease propagation. |
2021-11-26 |
2023-08-13 |
mouse |
| Anna Niewiadomska-Cimicka, Frédéric Doussau, Jean-Baptiste Perot, Michel J Roux, Celine Keime, Antoine Hache, Françoise Piguet, Ariana Novati, Chantal Weber, Binnaz Yalcin, Hamid Meziane, Marie-France Champy, Erwan Grandgirard, Alice Karam, Nadia Messaddeq, Aurélie Eisenmann, Emmanuel Brouillet, Hoa Huu Phuc Nguyen, Julien Flament, Philippe Isope, Yvon Trottie. SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 22. 2021-11-19. PMID:33888607. |
spinocerebellar ataxia type 7 (sca7) is an inherited neurodegenerative disease mainly characterized by motor incoordination because of progressive cerebellar degeneration. |
2021-11-19 |
2023-08-13 |
mouse |
| Angela Sanna, Paolo Follesa, Paolo Tacconi, Mariangela Serra, Maria Giuseppina Pisu, Viola Cocco, Michela Figorilli, Giovanni Defazio, Monica Pulighedd. Therapeutic Use of Cerebellar Intermittent Theta Burst Stimulation (iTBS) in a Sardinian Family Affected by Spinocerebellar Ataxia 38 (SCA 38). Cerebellum (London, England). 2021-11-11. PMID:34410614. |
therapeutic use of cerebellar intermittent theta burst stimulation (itbs) in a sardinian family affected by spinocerebellar ataxia 38 (sca 38). |
2021-11-11 |
2023-08-13 |
Not clear |
| Pamela McMillan, Jeanna Wheeler, Rachel E Gatlin, Laura Taylor, Tim Strovas, Misa Baum, Thomas D Bird, Caitlin Latimer, C Dirk Keene, Brian C Kraemer, Nicole F Liachk. Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice. Acta neuropathologica communications. vol 8. issue 1. 2021-11-09. PMID:33228809. |
these ittbk1 tg mice exhibit phenotypes reminiscent of spinocerebellar ataxia, and represent a new model of cerebellar neurodegeneration. |
2021-11-09 |
2023-08-13 |
mouse |
| Xiaodi Li, Xiao Lv, Churong Liu, Jinlong Ye, Yan Xu, Gengmao Ma, Zhong Li, Yuzhou Wan. 3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography. Cerebellum (London, England). vol 20. issue 2. 2021-11-05. PMID:33164129. |
a static posturography examination was administered to 37 persons with spinocerebellar ataxia, 58 others with the cerebellar type of multiple system atrophy, and 53 healthy controls. |
2021-11-05 |
2023-08-13 |
human |
| Fan Wu, Xu Wang, Xiaohan Li, Huidi Teng, Tao Tian, Jing Ba. Spinocerebellar ataxia type 23 (SCA23): a review. Journal of neurology. vol 268. issue 12. 2021-11-04. PMID:33175256. |
spinocerebellar ataxias (scas), formerly known as autosomal dominant cerebellar ataxias (adcas), are a group of hereditary heterogeneous neurodegenerative diseases. |
2021-11-04 |
2023-08-13 |
Not clear |
| Raghavendra Y Nagaraja, David M Sherry, Jennifer L Fessler, Megan A Stiles, Feng Li, Karanpreet Multani, Albert Orock, Mohiuddin Ahmad, Richard S Brush, Robert E Anderson, Martin-Paul Agbaga, Ferenc Deá. W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34227061. |
spinocerebellar ataxia (sca) is a neurodegenerative disorder characterized by ataxia and cerebellar atrophy. |
2021-10-27 |
2023-08-13 |
rat |
| Won-Seok Lee, Laura Lavery, Maxime W C Rousseaux, Eric B Rutledge, Youjin Jang, Ying-Wooi Wan, Sih-Rong Wu, Wonho Kim, Ismael Al-Ramahi, Smruti Rath, Carolyn J Adamski, Vitaliy V Bondar, Ambika Tewari, Shirin Soleimani, Samantha Mota, Hari K Yalamanchili, Harry T Orr, Zhandong Liu, Juan Botas, Huda Y Zoghb. Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1. The EMBO journal. vol 40. issue 7. 2021-10-22. PMID:33709453. |
in spinocerebellar ataxia type 1 (sca1), accumulation of polyglutamine-expanded ataxin-1 (atxn1) causes selective degeneration of cerebellar and brainstem neurons. |
2021-10-22 |
2023-08-13 |
mouse |
| John H Pula, Vernon L Towle, Victoria M Staszak, Dingcai Cao, Jacqueline T Bernard, Christopher M Gome. Retinal Nerve Fibre Layer and Macular Thinning in Spinocerebellar Ataxia and Cerebellar Multisystem Atrophy. Neuro-ophthalmology (Aeolus Press). vol 35. issue 3. 2021-10-20. PMID:21866205. |
retinal nerve fibre layer and macular thinning in spinocerebellar ataxia and cerebellar multisystem atrophy. |
2021-10-20 |
2023-08-12 |
human |
| Yoko Takahashi, Masaya Kubota, Rika Kosaki, Kenjiro Kosaki, Akira Ishigur. A severe form of autosomal recessive spinocerebellar ataxia associated with novel PMPCA variants. Brain & development. vol 43. issue 3. 2021-10-04. PMID:33272776. |
spinocerebellar ataxia, autosomal recessive 2 (scar2) [mim:213200] is a rare autosomal recessive disease of spinocerebellar ataxia associated with degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. |
2021-10-04 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Bart P C van de Warrenburg, Dennis J L G Schutte. Inverse associations between cerebellar inhibition and motor impairment in spinocerebellar ataxia type 3. Brain stimulation. vol 14. issue 2. 2021-10-04. PMID:33535082. |
inverse associations between cerebellar inhibition and motor impairment in spinocerebellar ataxia type 3. |
2021-10-04 |
2023-08-13 |
Not clear |
| Polina A Egorova, Aleksandra V Gavrilova, Ilya B Bezprozvann. In vivo analysis of the spontaneous firing of cerebellar Purkinje cells in awake transgenic mice that model spinocerebellar ataxia type 2. Cell calcium. vol 93. 2021-09-24. PMID:33248384. |
cerebellar purkinje cells (pcs) fire spontaneously in a tonic mode, although the precision of this pacemaking activity is disturbed in many abnormal conditions involving cerebellar atrophy, such as many spinocerebellar ataxias (scas). |
2021-09-24 |
2023-08-13 |
mouse |
| Jan Cendelin, Marija Cvetanovic, Mandi Gandelman, Hirokazu Hirai, Harry T Orr, Stefan M Pulst, Michael Strupp, Filip Tichanek, Jan Tuma, Mario Mant. Consensus Paper: Strengths and Weaknesses of Animal Models of Spinocerebellar Ataxias and Their Clinical Implications. Cerebellum (London, England). 2021-09-23. PMID:34378174. |
spinocerebellar ataxias (scas) represent a large group of hereditary degenerative diseases of the nervous system, in particular the cerebellum, and other systems that manifest with a variety of progressive motor, cognitive, and behavioral deficits with the leading symptom of cerebellar ataxia. |
2021-09-23 |
2023-08-13 |
mouse |
| Jianping Hu, Xinyuan Chen, Mengcheng Li, Hao-Ling Xu, Ziqiang Huang, Naping Chen, Yuqing Tu, Qunlin Chen, Shirui Gan, Dairong Ca. Pattern of cerebellar grey matter loss associated with ataxia severity in spinocerebellar ataxias type 3: a multi-voxel pattern analysis. Brain imaging and behavior. 2021-08-21. PMID:34417969. |
pattern of cerebellar grey matter loss associated with ataxia severity in spinocerebellar ataxias type 3: a multi-voxel pattern analysis. |
2021-08-21 |
2023-08-13 |
human |
| Jianping Hu, Xinyuan Chen, Mengcheng Li, Hao-Ling Xu, Ziqiang Huang, Naping Chen, Yuqing Tu, Qunlin Chen, Shirui Gan, Dairong Ca. Pattern of cerebellar grey matter loss associated with ataxia severity in spinocerebellar ataxias type 3: a multi-voxel pattern analysis. Brain imaging and behavior. 2021-08-21. PMID:34417969. |
spinocerebellar ataxias type 3 (sca3) patients are clinically characterized by progressive cerebellar ataxia combined with degeneration of the cerebellum. |
2021-08-21 |
2023-08-13 |
human |
| Giulia Coarelli, Frederic Darios, Emilien Petit, Karim Dorgham, Isaac Adanyeguh, Elodie Petit, Alexis Brice, Fanny Mochel, Alexandra Dur. Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia. Neurobiology of disease. vol 153. 2021-08-20. PMID:33636389. |
plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia. |
2021-08-20 |
2023-08-13 |
Not clear |
| Mohamed A Elsaey, Kazuhiko Namikawa, Reinhard W Köste. Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish. International journal of molecular sciences. vol 22. issue 14. 2021-08-17. PMID:34298970. |
dominant spinocerebellar ataxias (scas) are progredient neurodegenerative diseases commonly affecting the survival of purkinje cells (pcs) in the human cerebellum. |
2021-08-17 |
2023-08-13 |
human |
| Cleo J L M Smeets, Kai Yu Ma, Simon E Fisher, Dineke S Verbee. Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23. Brain pathology (Zurich, Switzerland). vol 31. issue 2. 2021-08-11. PMID:33043513. |
cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23. |
2021-08-11 |
2023-08-13 |
Not clear |
| Roberto Rodríguez-Labrada, Alejandro Batista-Izquierdo, Zuleyra González-Melix, Lorenzo Reynado-Cejas, Yaimeé Vázquez-Mojena, Yuri Arsenio Sanz, Nalia Canales-Ochoa, Yanetza González-Zaldívar, Imis Dogan, Kathrin Reetz, Luis Velázquez-Pére. Cognitive Decline Is Closely Associated with Ataxia Severity in Spinocerebellar Ataxia Type 2: a Validation Study of the Schmahmann Syndrome Scale. Cerebellum (London, England). 2021-07-27. PMID:34313938. |
the cerebellar cognitive affective syndrome scale (ccas-s) was designed to detect specific cognitive dysfunctions in cerebellar patients but is scarcely validated in spinocerebellar ataxias (sca). |
2021-07-27 |
2023-08-13 |
Not clear |
| Qing Lin, Yichen Chang, Peng Liu, Jeffery A Jones, Xi Chen, Danhua Peng, Mingyuan Chen, Chao Wu, Hanjun Li. Cerebellar Continuous Theta Burst Stimulation Facilitates Auditory-Vocal Integration in Spinocerebellar Ataxia. Cerebral cortex (New York, N.Y. : 1991). 2021-07-09. PMID:34240142. |
cerebellar continuous theta burst stimulation facilitates auditory-vocal integration in spinocerebellar ataxia. |
2021-07-09 |
2023-08-13 |
Not clear |