| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Szilvia E Mezey, Josef P Kapfhammer, Etsuko Shimobayash. Transcriptome Profile of a New Mouse Model of Spinocerebellar Ataxia Type 14 Implies Changes in Cerebellar Development. Genes. vol 13. issue 8. 2022-08-26. PMID:36011327. |
the autosomal dominant inherited spinocerebellar ataxias (scas) are a group of neurodegenerative disorders characterized by cerebellar atrophy and loss of purkinje neurons. |
2022-08-26 |
2023-08-14 |
mouse |
| Qin-Wei Wu, Josef P Kapfhamme. The Emerging Key Role of the mGluR1-PKCγ Signaling Pathway in the Pathogenesis of Spinocerebellar Ataxias: A Neurodevelopmental Viewpoint. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012439. |
spinocerebellar ataxias (scas) are a heterogeneous group of autosomal dominantly inherited progressive disorders with degeneration and dysfunction of the cerebellum. |
2022-08-26 |
2023-08-14 |
Not clear |
| Kimberly Luttik, Leon Tejwani, Hyoungseok Ju, Terri Driessen, Cleo J L M Smeets, Chandrakanth Reddy Edamakanti, Aryaan Khan, Joy Yun, Puneet Opal, Janghoo Li. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 34. 2022-08-15. PMID:35969780. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including purkinje cells (pcs) in the cerebellum. |
2022-08-15 |
2023-08-14 |
mouse |
| Ilaria Balbo, Francesca Montarolo, Federica Genovese, Filippo Tempia, Eriola Hoxh. Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model. Behavioral and brain functions : BBF. vol 18. issue 1. 2022-08-06. PMID:35933444. |
spinocerebellar ataxia 38 (sca38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. |
2022-08-06 |
2023-08-14 |
mouse |
| Victor Olmos, Neha Gogia, Kimberly Luttik, Fatema Haidery, Janghoo Li. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum. Cellular and molecular life sciences : CMLS. vol 79. issue 8. 2022-07-08. PMID:35802260. |
the extra-cerebellar effects of spinocerebellar ataxia type 1 (sca1): looking beyond the cerebellum. |
2022-07-08 |
2023-08-14 |
mouse |
| David D Bushart, Vikram G Shakkotta. Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies. Frontiers in systems neuroscience. vol 16. 2022-06-27. PMID:35757096. |
we also speculate on the vulnerability of cerebellar neurons to degeneration in mouse models of spinocerebellar ataxia (sca) where ion channel transcript dysregulation has recently been implicated in disease pathogenesis. |
2022-06-27 |
2023-08-14 |
mouse |
| Hung-Chieh Chen, Li-Hua Lee, Jiing-Feng Lirng, Bing-Wen Soon. Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732792. |
radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. |
2022-06-22 |
2023-08-14 |
Not clear |
| Hung-Chieh Chen, Li-Hua Lee, Jiing-Feng Lirng, Bing-Wen Soon. Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732792. |
differentiation cerebellar multiple systemic atrophy (msa-c) from spinocerebellar ataxia (sca) is important. |
2022-06-22 |
2023-08-14 |
Not clear |
| Pauline Bohne, Max Rybarski, Damian Boden-El Mourabit, Felix Krause, Melanie D Mar. Cerebellar contribution to threat probability in a SCA6 mouse model. Human molecular genetics. 2022-06-16. PMID:35708512. |
in this study we investigated the cerebellar contribution in evoking appropriate defensive escape behavior using a purely cerebellar, neurodegenerative mouse model for spinocerebellar ataxia type 6 (sca6) which is caused by an expanded cag repeat in exon 47 of the p/q type calcium channel α1a subunit. |
2022-06-16 |
2023-08-14 |
mouse |
| Kristin Mayoral-Palarz, Andreia Neves-Carvalho, Sara Duarte-Silva, Daniela Monteiro-Fernandes, Patrícia Maciel, Kamran Khodakha. Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. Disease models & mechanisms. 2022-06-06. PMID:35660856. |
cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. |
2022-06-06 |
2023-08-14 |
mouse |
| Francesco Gentile, Alessandro Bertini, Alberto Priori, Tommaso Bocc. Movement disorders and neuropathies: overlaps and mimics in clinical practice. Journal of neurology. 2022-06-03. PMID:35657406. |
finally, genetic causes should be pursued in case of positive family history, young onset or multisystemic involvement, and examined for neuroacanthocytosis, spinocerebellar ataxias, mitochondrial disorders and less common causes of adult-onset cerebellar ataxias and spastic paraparesis. |
2022-06-03 |
2023-08-14 |
Not clear |
| Xin-Yuan Chen, Yan-Hua Lian, Xia-Hua Liu, Arif Sikandar, Meng-Cheng Li, Hao-Ling Xu, Jian-Ping Hu, Qun-Lin Chen, Shi-Rui Ga. Effects of Repetitive Transcranial Magnetic Stimulation on Cerebellar Metabolism in Patients With Spinocerebellar Ataxia Type 3. Frontiers in aging neuroscience. vol 14. 2022-05-13. PMID:35547622. |
effects of repetitive transcranial magnetic stimulation on cerebellar metabolism in patients with spinocerebellar ataxia type 3. |
2022-05-13 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Steven Teerenstra, Ivan Toni, Thomas Klockgether, Dennis J L G Schutter, Bart P C van de Warrenbur. Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-05-02. PMID:35501469. |
cerebellar transcranial direct current stimulation in spinocerebellar ataxia type 3: a randomized, double-blind, sham-controlled trial. |
2022-05-02 |
2023-08-13 |
Not clear |
| Roderick P P W M Maas, Steven Teerenstra, Ivan Toni, Thomas Klockgether, Dennis J L G Schutter, Bart P C van de Warrenbur. Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia Type 3: a Randomized, Double-Blind, Sham-Controlled Trial. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-05-02. PMID:35501469. |
the objective of this study was to investigate if a two-week regimen of daily cerebellar tdcs sessions diminishes ataxia and non-motor symptom severity and alters cerebellar-m1 connectivity in individuals with spinocerebellar ataxia type 3 (sca3). |
2022-05-02 |
2023-08-13 |
Not clear |
| Hui Chen, Limeng Dai, Yuhan Zhang, Liu Feng, Zhenzhen Jiang, Xingang Wang, Dongjing Xie, Jing Guo, Huafu Chen, Jian Wang, Chen Li. Network Reconfiguration Among Cerebellar Visual, Frontiers in aging neuroscience. vol 14. 2022-04-28. PMID:35478700. |
network reconfiguration among cerebellar visual, spinocerebellar ataxia type 3 (sca3) is a rare movement disorder characterized with ataxia. |
2022-04-28 |
2023-08-13 |
Not clear |
| Anton N Shuvaev, Olga S Belozor, Oleg I Mozhei, Aleksandra G Mileiko, Ludmila D Mosina, Irina V Laletina, Ilia G Mikhailov, Yana V Fritsler, Andrey N Shuvaev, Anja G Teschemacher, Sergey Kasparo. Memantine Disrupts Motor Coordination through Anxiety-like Behavior in CD1 Mice. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35448027. |
we previously used memantine to prevent functional damage and to retain morphology of cerebellar neurons and bergmann glia in an optogenetic mouse model of spinocerebellar ataxia type-1 (sca1). |
2022-04-21 |
2023-08-13 |
mouse |
| Jiaqi Wang, Atsuhiko Sugiyama, Hajime Yokota, Shigeki Hirano, Graham Cooper, Hiroki Mukai, Kenji Ohira, Kyosuke Koide, Shoichi Ito, Carsten Finke, Alexander U Brandt, Friedemann Paul, Satoshi Kuwabar. Diagnostic efficacy of the magnetic resonance T1w/T2w ratio for the middle cerebellar peduncle in multiple system atrophy and spinocerebellar ataxia: A preliminary study. PloS one. vol 17. issue 4. 2022-04-15. PMID:35427382. |
diagnostic efficacy of the magnetic resonance t1w/t2w ratio for the middle cerebellar peduncle in multiple system atrophy and spinocerebellar ataxia: a preliminary study. |
2022-04-15 |
2023-08-13 |
Not clear |
| A Umano, K Fang, Z Qu, J B Scaglione, S Altinok, C J Treadway, E T Wick, E Paulakonis, C Karunanayake, S Chou, T M Bardakjian, P Gonzalez-Alegre, R C Page, J C Schisler, N G Brown, D Yan, K M Scaglion. The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP. The Journal of biological chemistry. 2022-04-10. PMID:35398354. |
the spinocerebellar ataxias (scas) are a class of incurable diseases characterized by degeneration of the cerebellum that results in movement disorder. |
2022-04-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Kazuhiko Yamaguchi, Jerome Honnorat, Mario Mant. The Clinical Concept of LTDpathy: Is Dysregulated LTD Responsible for Prodromal Cerebellar Symptoms? Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326260. |
on the other hand, in some types of spinocerebellar ataxia (sca), dysfunction in pf-pc ltd, and impairments of pf-pc ltd-related adaptive behaviors (including vestibulo-ocular reflex (vor) and prism adaptation) appear during the prodromal stage, well before the manifestations of obvious cas and cerebellar atrophy. |
2022-03-25 |
2023-08-13 |
Not clear |
| Marc Corral-Juan, Pilar Casquero, Natalia Giraldo-Restrepo, Steve Laurie, Alicia Martinez-Piñeiro, Raidili Cristina Mateo-Montero, Lourdes Ispierto, Dolores Vilas, Eduardo Tolosa, Victor Volpini, Ramiro Alvarez-Ramo, Ivelisse Sánchez, Antoni Matilla-Dueña. New spinocerebellar ataxia subtype caused by Brain communications. vol 4. issue 2. 2022-03-21. PMID:35310830. |
in this study, we describe a new spinocerebellar ataxia subtype in nine members of a spanish five-generation family from menorca with affected individuals variably presenting with ataxia, nystagmus, dysarthria, polyneuropathy, pyramidal signs, cerebellar atrophy and distinctive cerebral demyelination. |
2022-03-21 |
2023-08-13 |
Not clear |