| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robbert Havekes, Ted Abe. The tired hippocampus: the molecular impact of sleep deprivation on hippocampal function. Current opinion in neurobiology. vol 44. 2018-03-01. PMID:28242433. |
it is widely acknowledged that sleep deprivation has a profound effect on synaptic consolidation, particularly for memories that require the hippocampus. |
2018-03-01 |
2023-08-13 |
Not clear |
| Robbert Havekes, Ted Abe. The tired hippocampus: the molecular impact of sleep deprivation on hippocampal function. Current opinion in neurobiology. vol 44. 2018-03-01. PMID:28242433. |
in this review, we highlight recent studies showing that sleep deprivation impairs hippocampal camp and mtor signaling, and ultimately causes spine loss in ca1 neurons in a cofilin-dependent fashion. |
2018-03-01 |
2023-08-13 |
Not clear |
| Zhen Wang, Lu Chen, Ling Zhang, Xuemin Wan. Paradoxical sleep deprivation modulates depressive-like behaviors by regulating the MAOA levels in the amygdala and hippocampus. Brain research. vol 1664. 2018-02-22. PMID:28365314. |
paradoxical sleep deprivation modulates depressive-like behaviors by regulating the maoa levels in the amygdala and hippocampus. |
2018-02-22 |
2023-08-13 |
mouse |
| Fukie Niijima-Yaoita, Yuka Nagasawa, Masahiro Tsuchiya, Yuichiro Arai, Takeshi Tadano, Koichi Tan-N. Effects of methylphenidate on the impairment of spontaneous alternation behavior in mice intermittently deprived of REM sleep. Neurochemistry international. vol 100. 2018-01-31. PMID:27623091. |
in this study, using mice, we investigated whether intermittent rem sleep deprivation stress causes changes in sab and the expression of no synthase (nos) mrna and in the levels of no metabolites in the hippocampus. |
2018-01-31 |
2023-08-13 |
mouse |
| Fukie Niijima-Yaoita, Yuka Nagasawa, Masahiro Tsuchiya, Yuichiro Arai, Takeshi Tadano, Koichi Tan-N. Effects of methylphenidate on the impairment of spontaneous alternation behavior in mice intermittently deprived of REM sleep. Neurochemistry international. vol 100. 2018-01-31. PMID:27623091. |
the sab, the level of nitrite and expression of endothelial nos (enos) and inducible nos (inos) mrna in the hippocampus, but not neuronal nos (nnos), were significantly decreased by intermittent rem sleep deprivation stress. |
2018-01-31 |
2023-08-13 |
mouse |
| H Azizi, J Hwang, V Suen, N Z Kang, R Somvanshi, R Tadavarty, U Kumar, B R Sastr. Sleep deprivation induces changes in 5-HT actions and 5-HT Neuroscience letters. vol 655. 2018-01-01. PMID:28668380. |
sleep deprivation induces changes in 5-ht actions and 5-ht a 12h sleep deprivation enhances the expression of 5-hydroxytryptamine (5-ht) 1a receptors in rat hippocampus that recedes with 48h sleep recovery. |
2018-01-01 |
2023-08-13 |
rat |
| Isabella Panaccione, Luisa Iacovelli, Luigi di Nuzzo, Francesca Nardecchia, Gianluca Mauro, Delfina Janiri, Antonio De Blasi, Gabriele Sani, Ferdinando Nicoletti, Rosamaria Orland. Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. Pharmacological research. vol 117. 2017-12-27. PMID:27890550. |
paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. |
2017-12-27 |
2023-08-13 |
rat |
| Munder A Zagaar, An T Dao, Ibrahim A Alhaider, Karim A Alkadh. Prevention by Regular Exercise of Acute Sleep Deprivation-Induced Impairment of Late Phase LTP and Related Signaling Molecules in the Dentate Gyrus. Molecular neurobiology. vol 53. issue 5. 2017-12-22. PMID:25902862. |
sleep deprivation reduced the basal levels of phosphorylated camp response element-binding protein (p-creb) as well as other upstream modulators including calcium/calmodulin kinase iv (camkiv) and brain-derived neurotrophic factor (bdnf) in the dg of the hippocampus. |
2017-12-22 |
2023-08-13 |
rat |
| Jennifer C Tudor, Emily J Davis, Lucia Peixoto, Mathieu E Wimmer, Erik van Tilborg, Alan J Park, Shane G Poplawski, Caroline W Chung, Robbert Havekes, Jiayan Huang, Evelina Gatti, Philippe Pierre, Ted Abe. Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. Science signaling. vol 9. issue 425. 2017-12-05. PMID:27117251. |
increasing the abundance of 4ebp2 in hippocampal excitatory neurons before sleep deprivation increased the abundance of phosphorylated 4ebp2, restored the amount of eif4e-eif4g interaction and hippocampal protein synthesis to that seen in mice that were not sleep-deprived, and prevented the hippocampus-dependent memory deficits associated with sleep loss. |
2017-12-05 |
2023-08-13 |
mouse |
| Mengmei Yin, Yali Chen, Hui Zheng, Tinglin Pu, Charles Marshall, Ting Wu, Ming Xia. Assessment of mouse cognitive and anxiety-like behaviors and hippocampal inflammation following a repeated and intermittent paradoxical sleep deprivation procedure. Behavioural brain research. vol 321. 2017-11-29. PMID:28043900. |
assessment of mouse cognitive and anxiety-like behaviors and hippocampal inflammation following a repeated and intermittent paradoxical sleep deprivation procedure. |
2017-11-29 |
2023-08-13 |
mouse |
| Mak Adam Daulatza. Pharmacotherpy and Alzheimer's Disease: The M-Drugs (Melatonin, Minocycline, Modafinil, and Memantine) Approach. Current pharmaceutical design. vol 22. issue 16. 2017-11-16. PMID:26845126. |
sleep deprivation leads to decreased hippocampal neurogenesis, increased amyloid beta generation, and causes memory dysfunction. |
2017-11-16 |
2023-08-13 |
Not clear |
| Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abe. Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. eLife. vol 5. 2017-10-23. PMID:27549340. |
sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area ca1. |
2017-10-23 |
2023-08-13 |
mouse |
| Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abe. Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. eLife. vol 5. 2017-10-23. PMID:27549340. |
in mice, we find that five hours of sleep deprivation decreases dendritic spine numbers selectively in hippocampal area ca1 and increased activity of the filamentous actin severing protein cofilin. |
2017-10-23 |
2023-08-13 |
mouse |
| Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abe. Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. eLife. vol 5. 2017-10-23. PMID:27549340. |
suppression of cofilin function prevents spine loss, deficits in hippocampal synaptic plasticity, and impairments in long-term memory caused by sleep deprivation. |
2017-10-23 |
2023-08-13 |
mouse |
| Meetu Wadhwa, Punita Kumari, Garima Chauhan, Koustav Roy, Shahnawaz Alam, Krishna Kishore, Koushik Ray, Usha Panjwan. Sleep deprivation induces spatial memory impairment by altered hippocampus neuroinflammatory responses and glial cells activation in rats. Journal of neuroimmunology. vol 312. 2017-10-11. PMID:28912034. |
sleep deprivation induces spatial memory impairment by altered hippocampus neuroinflammatory responses and glial cells activation in rats. |
2017-10-11 |
2023-08-13 |
rat |
| Maxime O Baud, Julia Parafita, Audrey Nguyen, Pierre J Magistretti, Jean-Marie Peti. Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure. Journal of sleep research. vol 25. issue 5. 2017-10-05. PMID:27136914. |
our results suggest that long-term sleep fragmentation impaired brain metabolism to a similar extent as total sleep deprivation without affecting the neuronal responsiveness of hippocampus to a novel environment. |
2017-10-05 |
2023-08-13 |
mouse |
| Virginie Sterpenich, Leonardo Ceravolo, Sophie Schwart. Sleep deprivation disrupts the contribution of the hippocampus to the formation of novel lexical associations. Brain and language. vol 167. 2017-09-25. PMID:28173964. |
sleep deprivation disrupts the contribution of the hippocampus to the formation of novel lexical associations. |
2017-09-25 |
2023-08-13 |
human |
| Gabriela López-Armas, Mario Eduardo Flores-Soto, Verónica Chaparro-Huerta, Luis Felipe Jave-Suarez, Sofía Soto-Rodríguez, Iryna Rusanova, Dario Acuña-Castroviejo, Oscar González-Perez, Rocío Elizabeth González-Castañed. Prophylactic Role of Oral Melatonin Administration on Neurogenesis in Adult Balb/C Mice during REM Sleep Deprivation. Oxidative medicine and cellular longevity. vol 2016. 2017-07-14. PMID:27579149. |
the aim of this study was to assess the effect of melatonin in the proliferation of neural progenitors, melatonin concentration, and antiapoptotic proteins in the hippocampus of adult mice exposed to 96 h rem sleep deprivation (remsd) prophylactic administration of melatonin for 14 days. |
2017-07-14 |
2023-08-13 |
mouse |
| Xinyun Su, Chunhua Wang, Xiuhua Wang, Fang Han, Changjun Lv, Xiuli Zhan. Sweet Dream Liquid Chinese Medicine Ameliorates Learning and Memory Deficit in a Rat Model of Paradoxical Sleep Deprivation through the ERK/CREB Signaling Pathway. Journal of medicinal food. vol 19. issue 5. 2017-03-20. PMID:26870900. |
this study investigated the neuroprotective effect and the underlying mechanisms of sdol-impaired hippocampus learning and memory-induced paradoxical sleep deprivation (psd) in rats. |
2017-03-20 |
2023-08-13 |
rat |
| Tobias Kaufmann, Torbjørn Elvsåshagen, Dag Alnæs, Nathalia Zak, Per Ø Pedersen, Linn B Norbom, Sophia H Quraishi, Enzo Tagliazucchi, Helmut Laufs, Atle Bjørnerud, Ulrik F Malt, Ole A Andreassen, Evangelos Roussos, Eugene P Duff, Stephen M Smith, Inge R Groote, Lars T Westly. The brain functional connectome is robustly altered by lack of sleep. NeuroImage. vol 127. 2016-12-13. PMID:26712339. |
sleep deprivation strongly altered the connectivity of several resting-state networks, including dorsal attention, default mode, and hippocampal networks. |
2016-12-13 |
2023-08-13 |
human |