| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul A Yushkevich, Hui Zhang, James C Ge. Continuous medial representation for anatomical structures. IEEE transactions on medical imaging. vol 25. issue 12. 2007-02-22. PMID:17167991. |
an efficient variational algorithm for deformable template modeling using the continuous medial representation is described and used to fit a template to the hippocampus in 87 subjects from a schizophrenia study with sub-voxel accuracy and 95% mean overlap. |
2007-02-22 |
2023-08-12 |
human |
| Xinzhi Zhao, Ruqi Tang, Bo Gao, Yongyong Shi, Jian Zhou, Shengzhen Guo, Jing Zhang, Yabing Wang, Wei Tang, Junwei Meng, Sheng Li, Hongsheng Wang, Gang Ma, Chuwen Lin, Yue Xiao, Guoyin Feng, Zhiguang Lin, Shaomin Zhu, Yangling Xing, Hong Sang, David St Clair, Lin H. Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia. American journal of human genetics. vol 80. issue 1. 2007-02-12. PMID:17160890. |
the chitinase 3-like 1 gene (chi3l1) is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia. |
2007-02-12 |
2023-08-12 |
human |
| Johann Steiner, Christian Mawrin, Anke Ziegeler, Hendrik Bielau, Oliver Ullrich, Hans-Gert Bernstein, Bernhard Bogert. Distribution of HLA-DR-positive microglia in schizophrenia reflects impaired cerebral lateralization. Acta neuropathologica. vol 112. issue 3. 2007-02-08. PMID:16783554. |
dorsolateral prefrontal cortex (dlpfc), anterior cingulate cortex (acc), hippocampus and mediodorsal thalamus (md) were studied in 16 cases with schizophrenia and 16 control subjects. |
2007-02-08 |
2023-08-12 |
human |
| Linda W Jurata, Paul Gallagher, Andrew L Lemire, Vinod Charles, Jeffrey A Brockman, Elizabeth Lindsay Illingworth, C Anthony Alta. Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome. Schizophrenia research. vol 88. issue 1-3. 2007-02-06. PMID:17008057. |
df1/+ mice are mostly viable but display deficits in prepulse inhibition and learning and memory, two common traits of schizophrenia thought to result, at least in part, from defects in hippocampal neurons. |
2007-02-06 |
2023-08-12 |
mouse |
| Katja Schulze, James H MacCabe, Sophia Rabe-Hesketh, Trevor Crawford, Nicolette Marshall, Jolanta Zanelli, Muriel Walshe, Elvira Bramon, Robin M Murray, Colm McDonal. The relationship between eye movement and brain structural abnormalities in patients with schizophrenia and their unaffected relatives. Journal of psychiatric research. vol 40. issue 7. 2007-01-29. PMID:15979644. |
the relationship between quantitative measures of eye movement task performance (smooth pursuit and antisaccade) and mri volumetric measurements (whole brain volume, prefrontal region, lateral ventricles, third ventricle, hippocampus, and cerebellum) was assessed in 70 patients with schizophrenia or schizoaffective disorder, 105 of their unaffected first-degree relatives and 68 controls. |
2007-01-29 |
2023-08-12 |
Not clear |
| S Totterdel. The anatomy of co-morbid neuropsychiatric disorders based on cortico-limbic synaptic interactions. Neurotoxicity research. vol 10. issue 2. 2007-01-03. PMID:17062369. |
furthermore, the control of motivational behaviour and dopamine release is apparently modified by hippocampal and amygdala activity, both brain regions showing pathological changes in schizophrenia and depression. |
2007-01-03 |
2023-08-12 |
Not clear |
| Ulrich Sprick, Martina von Wilmsdorff, Marie-Luise Bouvier, Daniela Schulz, Wolfgang Gaebe. Behavioral and hippocampal changes after prenatal invasive interventions with possible relevance to schizophrenia. Behavioural brain research. vol 172. issue 2. 2006-12-28. PMID:16806517. |
behavioral and hippocampal changes after prenatal invasive interventions with possible relevance to schizophrenia. |
2006-12-28 |
2023-08-12 |
human |
| Ulrich Sprick, Martina von Wilmsdorff, Marie-Luise Bouvier, Daniela Schulz, Wolfgang Gaebe. Behavioral and hippocampal changes after prenatal invasive interventions with possible relevance to schizophrenia. Behavioural brain research. vol 172. issue 2. 2006-12-28. PMID:16806517. |
in an attempt to model neurodevelopmental defects that may contribute to the outbreak of schizophrenia after adolescence, the present study examined the effects of prenatal interventions in rats, including injections of kainic acid, on motor, cognitive and social behaviour, which was assessed repeatedly between pds 56-62 (week 8) and 168-174 (week 24), as well as on hippocampal morphology. |
2006-12-28 |
2023-08-12 |
human |
| Ulrich Sprick, Martina von Wilmsdorff, Marie-Luise Bouvier, Daniela Schulz, Wolfgang Gaebe. Behavioral and hippocampal changes after prenatal invasive interventions with possible relevance to schizophrenia. Behavioural brain research. vol 172. issue 2. 2006-12-28. PMID:16806517. |
thus, the prenatally treated offspring showed certain alterations in their brains and behaviour that resembled the human condition of schizophrenia (e.g., changes at cell level in the hippocampus, perseverative behaviour, lower weight gains), although others (e.g., increased social contacts) did not. |
2006-12-28 |
2023-08-12 |
human |
| Barbara K Lipska, Shruti N Mitkus, Shiny V Mathew, Robert Fatula, Thomas M Hyde, Daniel R Weinberger, Joel E Kleinma. Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia. Dialogues in clinical neuroscience. vol 8. issue 3. 2006-12-20. PMID:17117617. |
the disrupted in schizophrenia 1 (disc1) gene has been identified as a schizophrenia susceptibility gene based on linkage and single nucleotide polymorphism (snp) association studies and clinical data, suggesting that risk snps impact on hippocampal structure and function. |
2006-12-20 |
2023-08-12 |
human |
| Barbara K Lipska, Shruti Mitkus, Mark Caruso, Thomas M Hyde, Jingshan Chen, Radhakrishna Vakkalanka, Richard E Straub, Daniel R Weinberger, Joel E Kleinma. RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity. Human molecular genetics. vol 15. issue 18. 2006-11-08. PMID:16905560. |
we compared rgs4 mrna expression in the dorsolateral prefrontal cortex (dlpfc), between normal controls and patients with schizophrenia in two independent cohorts (>100 subjects each) (the cbdb/nimh collection and the stanley array collection), and in the hippocampus in the cbdb/nimh collection. |
2006-11-08 |
2023-08-12 |
human |
| Kuei Y Tseng, Fatema Amin, Barbara L Lewis, Patricio O'Donnel. Altered prefrontal cortical metabolic response to mesocortical activation in adult animals with a neonatal ventral hippocampal lesion. Biological psychiatry. vol 60. issue 6. 2006-11-01. PMID:16780812. |
adult animals with a neonatal ventral hippocampal lesion (nvhl) exhibit deficits in working memory and sensorimotor gating similar to those observed in schizophrenia. |
2006-11-01 |
2023-08-12 |
Not clear |
| S Mexal, R Berger, C E Adams, R G Ross, R Freedman, S Leonar. Brain pH has a significant impact on human postmortem hippocampal gene expression profiles. Brain research. vol 1106. issue 1. 2006-11-01. PMID:16843448. |
one region that has not yet been evaluated in such studies is the hippocampus, a region often implicated in schizophrenia research. |
2006-11-01 |
2023-08-12 |
human |
| S Mexal, R Berger, C E Adams, R G Ross, R Freedman, S Leonar. Brain pH has a significant impact on human postmortem hippocampal gene expression profiles. Brain research. vol 1106. issue 1. 2006-11-01. PMID:16843448. |
brain ph accounted for greater variation in hippocampal gene expression profiles than any other parameter evaluated, including gender and schizophrenia. |
2006-11-01 |
2023-08-12 |
human |
| Matthew L MacDonald, Alipi Naydenov, Melissa Chu, David Matzilevich, Christine Konrad. Decrease in creatine kinase messenger RNA expression in the hippocampus and dorsolateral prefrontal cortex in bipolar disorder. Bipolar disorders. vol 8. issue 3. 2006-10-31. PMID:16696827. |
to further explore this hypothesis, we examined levels of creatine kinase (ck) mrna, the enzyme involved in synthesis and metabolism of pcr, in the hippocampus (hip) and dorsolateral prefrontal cortex (dlpfc) of control, bpd and schizophrenia subjects. |
2006-10-31 |
2023-08-12 |
human |
| Edward D Levin, Amir H Rezvan. Nicotinic-antipsychotic drug interactions and cognitive function. EXS. vol 98. 2006-10-31. PMID:17019889. |
chronic hippocampal nicotinic antagonist infusions have served as a model of persistent decreases in nicotinic receptor level seen in schizophrenia and alzheimer's disease. |
2006-10-31 |
2023-08-12 |
human |
| Celine Hoareau, Franck Hazane, Gwenaëlle Le Pen, Marie-Odile Kreb. Postnatal effect of embryonic neurogenesis disturbance on reelin level in organotypic cultures of rat hippocampus. Brain research. vol 1097. issue 1. 2006-10-06. PMID:16733048. |
in the rat, intraperitoneal injection of the anti-mitotic agent methylazoxymethanol (mam) during intra-uterine development (embryonic day 17) induces cytoarchitectural abnormalities in the hippocampus and the cortex and behavioural changes reminiscent of positive, negative and cognitive symptoms of schizophrenia. |
2006-10-06 |
2023-08-12 |
rat |
| István Szendi, Marianna Kiss, Mihály Racsmány, Krisztina Boda, Csongor Cimmer, Erika Vörös, Zoltán A Kovács, György Szekeres, Gabriella Galsi, Csaba Pléh, László Csernay, Zoltán Jank. Correlations between clinical symptoms, working memory functions and structural brain abnormalities in men with schizophrenia. Psychiatry research. vol 147. issue 1. 2006-10-05. PMID:16545554. |
thirteen male patients with schizophrenia and thirteen male normal control subjects were compared by magnetic resonance imaging (mri) on volumes of the straight gyrus (sg), anterior cingulate gyrus, middle frontal gyrus, hippocampus, third ventricle, cavum septi pellucidi, total brain volume and intracranial volume. |
2006-10-05 |
2023-08-12 |
human |
| L Lecourtier, O Deschaux, C Arnaud, A Chessel, P H Kelly, R Garci. Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16716523. |
both the habenula and the nucleus accumbens, and especially the glutamatergic innervation of the latter from the hippocampus, have been hypothesized to be involved, in different ways, in the pathophysiology of cognitive disturbances in schizophrenia. |
2006-10-04 |
2023-08-12 |
rat |
| b' T Kasp\\xc3\\xa1rek, R Prikryl, D Schwarz, H Kucerov\\xc3\\xa1, E Ceskov\\xc3\\xa. [Hippocampus, structure of the brain and schizophrenia]. Casopis lekaru ceskych. vol 145. issue 7. 2006-10-03. PMID:16921782.' |
[hippocampus, structure of the brain and schizophrenia]. |
2006-10-03 |
2023-08-12 |
Not clear |