| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zakaria Ouhaz, Saadia Ba-M'hamed, Mohamed Benni. Haloperidol treatment at pre-exposure phase reduces the disturbance of latent inhibition in rats with neonatal ventral hippocampus lesions. Comptes rendus biologies. vol 337. issue 10. 2015-06-01. PMID:25282171. |
animals with neonatal ventral hippocampal lesions develop during or after adolescence abnormal behaviors related to schizophrenia such as anxiety and latent inhibition disruption. |
2015-06-01 |
2023-08-13 |
rat |
| Regina F Nasyrova, Dmitriy V Ivashchenko, Mikhail V Ivanov, Nikolay G Neznano. Role of nitric oxide and related molecules in schizophrenia pathogenesis: biochemical, genetic and clinical aspects. Frontiers in physiology. vol 6. 2015-06-01. PMID:26029110. |
investigations reveal significant disturbances in no levels in the brain structures (cerebellum, hypothalamus, hippocampus, striatum) and fluids of subjects with schizophrenia. |
2015-06-01 |
2023-08-13 |
human |
| Pritsana Piyabhan, Thanitsara Wetchaten. Neuroprotective effects of Bacopa monnieri (Brahmi) on novel object recognition and NMDAR1 immunodensity in the prefrontal cortex, striatum and hippocampus of sub-chronic phencyclidine rat model of schizophrenia. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 97 Suppl 8. 2015-05-26. PMID:25518293. |
neuroprotective effects of bacopa monnieri (brahmi) on novel object recognition and nmdar1 immunodensity in the prefrontal cortex, striatum and hippocampus of sub-chronic phencyclidine rat model of schizophrenia. |
2015-05-26 |
2023-08-13 |
rat |
| Diana Xuan Yu, Francesco Paolo Di Giorgio, Jun Yao, Maria Carolina Marchetto, Kristen Brennand, Rebecca Wright, Arianna Mei, Lauren McHenry, David Lisuk, Jaeson Michael Grasmick, Pedro Silberman, Giovanna Silberman, Roberto Jappelli, Fred H Gag. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem cell reports. vol 2. issue 3. 2015-05-22. PMID:24672753. |
because hippocampal neurogenesis has been implicated in schizophrenia (sczd), we applied our protocol to sczd patient-derived human induced pluripotent stem cells (hipscs). |
2015-05-22 |
2023-08-12 |
human |
| Paola Bossù, Fabrizio Piras, Ilaria Palladino, Mariangela Iorio, Francesca Salani, Antonio Ciaramella, Chiara Chiapponi, Carlo Caltagirone, Gianfranco Spallett. Hippocampal volume and depressive symptoms are linked to serum IL-18 in schizophrenia. Neurology(R) neuroimmunology & neuroinflammation. vol 2. issue 4. 2015-05-15. PMID:25977936. |
hippocampal volume and depressive symptoms are linked to serum il-18 in schizophrenia. |
2015-05-15 |
2023-08-13 |
Not clear |
| Paola Bossù, Fabrizio Piras, Ilaria Palladino, Mariangela Iorio, Francesca Salani, Antonio Ciaramella, Chiara Chiapponi, Carlo Caltagirone, Gianfranco Spallett. Hippocampal volume and depressive symptoms are linked to serum IL-18 in schizophrenia. Neurology(R) neuroimmunology & neuroinflammation. vol 2. issue 4. 2015-05-15. PMID:25977936. |
since schizophrenia (scz) is often accompanied by hippocampal abnormalities and dysregulation of cytokine production, this study aimed to investigate the impact of the cytokine interleukin (il)-18, whose biological system appears to be perturbed in scz, on brain structure and clinical severity in patients with chronic scz. |
2015-05-15 |
2023-08-13 |
Not clear |
| Rachel A Hill, Maren Klug, Szerenke Kiss Von Soly, Michele D Binder, Anthony J Hannan, Maarten van den Buus. Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling. Hippocampus. vol 24. issue 10. 2015-05-12. PMID:24802968. |
post-mortem studies have demonstrated reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus of schizophrenia and major depression patients. |
2015-05-12 |
2023-08-13 |
rat |
| Joon Seol Bae, Jason Yongha Kim, Byung-Lae Park, Jeong-Hyun Kim, Bomi Kim, Chul Soo Park, Bong-Jo Kim, Cheol-Soon Lee, Migyung Lee, Woo Hyuk Choi, Tae-Min Shin, Jaeuk Hwang, Hyoung Doo Shin, Sung-Il Wo. Genetic association analysis of CNR1 and CNR2 polymorphisms with schizophrenia in a Korean population. Psychiatric genetics. vol 24. issue 5. 2015-05-12. PMID:25014618. |
located on 6q15 and 1p36.11, cannabinoid receptor 1 (cnr1) and cannabinoid receptor 2 (cnr2) genes are considered to be a positional and functional candidate gene for the development of mental disorders such as schizophrenia because cnr1 is known as a regulator of dopamine signaling in the hippocampus and the cerebral cortex. |
2015-05-12 |
2023-08-13 |
Not clear |
| Stephanie M Perez, Daniel J Lodg. New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways. Drug design, development and therapy. vol 8. 2015-05-11. PMID:25061280. |
new approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways. |
2015-05-11 |
2023-08-13 |
rat |
| Stephanie M Perez, Daniel J Lodg. New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways. Drug design, development and therapy. vol 8. 2015-05-11. PMID:25061280. |
here we review the dopamine, gamma-aminobutyric acid (gaba), and glutamate hypotheses of schizophrenia and describe a pathway whereby a loss of inhibitory signaling in ventral regions of the hippocampus actually drives a dopamine hyperfunction. |
2015-05-11 |
2023-08-13 |
rat |
| Christina Josefa Herold, Marc Montgomery Lässer, Lena Anna Schmid, Ulrich Seidl, Li Kong, Iven Fellhauer, Philipp Arthur Thomann, Marco Essig, Johannes Schröde. Neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia. Frontiers in psychiatry. vol 6. 2015-05-08. PMID:25954208. |
neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia. |
2015-05-08 |
2023-08-13 |
Not clear |
| Christina Josefa Herold, Marc Montgomery Lässer, Lena Anna Schmid, Ulrich Seidl, Li Kong, Iven Fellhauer, Philipp Arthur Thomann, Marco Essig, Johannes Schröde. Neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia. Frontiers in psychiatry. vol 6. 2015-05-08. PMID:25954208. |
therefore, we investigated hippocampal volume and am along with important neuropsychological domains in patients with chronic schizophrenia and the respective relationships between these parameters. |
2015-05-08 |
2023-08-13 |
Not clear |
| Christina Josefa Herold, Marc Montgomery Lässer, Lena Anna Schmid, Ulrich Seidl, Li Kong, Iven Fellhauer, Philipp Arthur Thomann, Marco Essig, Johannes Schröde. Neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia. Frontiers in psychiatry. vol 6. 2015-05-08. PMID:25954208. |
we compared 25 older patients with chronic schizophrenia to 23 younger patients and an older healthy control group (n = 21) with respect to am, additional neuropsychological parameters, and hippocampal volume. |
2015-05-08 |
2023-08-13 |
Not clear |
| Christina Josefa Herold, Marc Montgomery Lässer, Lena Anna Schmid, Ulrich Seidl, Li Kong, Iven Fellhauer, Philipp Arthur Thomann, Marco Essig, Johannes Schröde. Neuropsychology, autobiographical memory, and hippocampal volume in "younger" and "older" patients with chronic schizophrenia. Frontiers in psychiatry. vol 6. 2015-05-08. PMID:25954208. |
these findings underline the complexity of am and its impairments in the course of schizophrenia in comparison to rather progressive neuropsychological deficits and address the importance of hippocampal contribution. |
2015-05-08 |
2023-08-13 |
Not clear |
| Sonia Guzmán-Velázquez, Linda Garcés-Ramírez, Gonzalo Flores, Fidel De La Cruz, Sergio R Zamudi. Differential Effect of the Dopamine D3 Agonist (±)-7-Hydroxy-2-(N,N-di-n-propylamino) Tetralin (7-OH-DPAT) on Motor Activity between Adult Wistar and Sprague-Dawley Rats after a Neonatal Ventral Hippocampus Lesion. International journal of medicinal chemistry. vol 2011. 2015-05-08. PMID:25954521. |
the neonatal ventral hippocampal lesion (nvhl) has been widely used as an animal model for schizophrenia. |
2015-05-08 |
2023-08-13 |
rat |
| Amy E Geddes, Xu-Feng Huang, Kelly A Newel. GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia. BMC psychiatry. vol 14. 2015-04-29. PMID:25292222. |
glun2b protein deficits in the left, but not the right, hippocampus in schizophrenia. |
2015-04-29 |
2023-08-13 |
human |
| Amy E Geddes, Xu-Feng Huang, Kelly A Newel. GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia. BMC psychiatry. vol 14. 2015-04-29. PMID:25292222. |
the hippocampus plays a key role in cognitive function, with studies suggesting lateralised glutamatergic dysfunction in this region may contribute to the cognitive deficits observed in schizophrenia patients. |
2015-04-29 |
2023-08-13 |
human |
| Amy E Geddes, Xu-Feng Huang, Kelly A Newel. GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia. BMC psychiatry. vol 14. 2015-04-29. PMID:25292222. |
the present study, for the first time, investigated glun2b protein and binding density in the left and right hippocampus of 20 schizophrenia subjects compared to 20 matched controls. |
2015-04-29 |
2023-08-13 |
human |
| Owen G O'Daly, Daniel Joyce, Derek K Tracy, Klaas E Stephan, Robin M Murray, Sukhwinder Shergil. Amphetamine sensitisation and memory in healthy human volunteers: a functional magnetic resonance imaging study. Journal of psychopharmacology (Oxford, England). vol 28. issue 9. 2015-04-19. PMID:24671338. |
recent data suggest that the enhanced excitability of mesolimbic dopamine neurons in as is driven by a hyperactivity of hippocampal (subiculum) neurons, consistent with a strong association between hippocampal dysfunction and schizophrenia. |
2015-04-19 |
2023-08-12 |
human |
| Jason Smucny, Adrienne Visani, Jason R Tregella. Could vagus nerve stimulation target hippocampal hyperactivity to improve cognition in schizophrenia? Frontiers in psychiatry. vol 6. 2015-04-08. PMID:25852579. |
could vagus nerve stimulation target hippocampal hyperactivity to improve cognition in schizophrenia? |
2015-04-08 |
2023-08-13 |
Not clear |