| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Garry D Honey, Philip R Corlett, Anthony R Absalom, Michael Lee, Edith Pomarol-Clotet, Graham K Murray, Peter J McKenna, Edward T Bullmore, David K Menon, Paul C Fletche. Individual differences in psychotic effects of ketamine are predicted by brain function measured under placebo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 25. 2008-07-10. PMID:18562599. |
a subpsychotic dose of ketamine administered during a second scanning session resulted in increased basal ganglia and thalamic activation during the working memory task, paralleling previous reports in patients with schizophrenia. |
2008-07-10 |
2023-08-12 |
human |
| C J Schmidt, D S Chapin, J Cianfrogna, M L Corman, M Hajos, J F Harms, W E Hoffman, L A Lebel, S A McCarthy, F R Nelson, C Proulx-LaFrance, M J Majchrzak, A D Ramirez, K Schmidt, P A Seymour, J A Siuciak, F D Tingley, R D Williams, P R Verhoest, F S Mennit. Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. The Journal of pharmacology and experimental therapeutics. vol 325. issue 2. 2008-05-19. PMID:18287214. |
these new pharmacological tools enabled studies that provide further evidence that inhibition of pde10a represents an important new target for the treatment of schizophrenia and related disorders of basal ganglia function. |
2008-05-19 |
2023-08-12 |
Not clear |
| Szabolcs Kér. Interactive memory systems and category learning in schizophrenia. Neuroscience and biobehavioral reviews. vol 32. issue 2. 2008-05-02. PMID:17854895. |
whereas executive and declarative memory dysfunctions are well known in schizophrenia, habit learning deficits related to the basal ganglia are less clear, despite the fact that dopaminergic and other neurochemical processes in the basal ganglia may play a crucial role in the pathophysiology and pharmacology of schizophrenia. |
2008-05-02 |
2023-08-12 |
Not clear |
| Agata Szul. [First and second generation antipsychotics and morphological and neurochemical brain changes in schizophrenia. Review of magnetic resonance imaging and proton spectroscopy findings]. Psychiatria polska. vol 41. issue 3. 2007-10-19. PMID:17900049. |
the most replicated findings in schizophrenia are: an increase of basal ganglia volume and decrease of grey matter in different regions (after typical neuroleptics). |
2007-10-19 |
2023-08-12 |
Not clear |
| Neil D Woodward, Phil Tibbo, Scot E Purdo. An fMRI investigation of procedural learning in unaffected siblings of individuals with schizophrenia. Schizophrenia research. vol 94. issue 1-3. 2007-10-11. PMID:17544630. |
previous functional magnetic resonance imaging (fmri) investigations of procedural learning in patients with schizophrenia identified reduced activity in the frontal cortex, basal ganglia, and parietal cortex during performance of the serial reaction time (srt) task suggesting that abnormal function of these regions may relate to genetic vulnerability for schizophrenia. |
2007-10-11 |
2023-08-12 |
human |
| Neil D Woodward, Phil Tibbo, Scot E Purdo. An fMRI investigation of procedural learning in unaffected siblings of individuals with schizophrenia. Schizophrenia research. vol 94. issue 1-3. 2007-10-11. PMID:17544630. |
identification of genes related to the function of cerebral regions such as the prefrontal cortex, parietal lobe, and basal ganglia may assist in delineating the genetic contributions to schizophrenia. |
2007-10-11 |
2023-08-12 |
human |
| P Stathis, I G Panourias, M S Themistocleous, D E Saka. Connections of the basal ganglia with the limbic system: implications for neuromodulation therapies of anxiety and affective disorders. Acta neurochirurgica. Supplement. vol 97. issue Pt 2. 2007-09-26. PMID:17691350. |
pathophysiological processes underlying psychiatric disorders such as depression, obsessive compulsive disorder and even schizophrenia involve the basal ganglia and their connections to many other structures and particularly to the prefrontal cortex and the limbic system. |
2007-09-26 |
2023-08-12 |
Not clear |
| b' Andreas Glenthoj, Birte Y Glenthoj, Torben Mackeprang, Anne K Pagsberg, Ralf P Hemmingsen, Terry L Jernigan, William F C Baar\\xc3\\xa. Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. Psychiatry research. vol 154. issue 3. 2007-07-03. PMID:17360162.' |
basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. |
2007-07-03 |
2023-08-12 |
Not clear |
| Marin Veldic, Bashkim Kadriu, Ekrem Maloku, Roberto C Agis-Balboa, Alessandro Guidotti, John M Davis, Erminio Cost. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophrenia research. vol 91. issue 1-3. 2007-06-12. PMID:17270400. |
epigenetic mechanisms expressed in basal ganglia gabaergic neurons differentiate schizophrenia from bipolar disorder. |
2007-06-12 |
2023-08-12 |
human |
| Daniel Mamah, Lei Wang, Deanna Barch, Gabriel A de Erausquin, Mokhtar Gado, John G Csernansk. Structural analysis of the basal ganglia in schizophrenia. Schizophrenia research. vol 89. issue 1-3. 2007-04-03. PMID:17071057. |
structural analysis of the basal ganglia in schizophrenia. |
2007-04-03 |
2023-08-12 |
human |
| Daniel Mamah, Lei Wang, Deanna Barch, Gabriel A de Erausquin, Mokhtar Gado, John G Csernansk. Structural analysis of the basal ganglia in schizophrenia. Schizophrenia research. vol 89. issue 1-3. 2007-04-03. PMID:17071057. |
increases in the total volume of basal ganglia structures have been reported in schizophrenia. |
2007-04-03 |
2023-08-12 |
human |
| Daniel Mamah, Lei Wang, Deanna Barch, Gabriel A de Erausquin, Mokhtar Gado, John G Csernansk. Structural analysis of the basal ganglia in schizophrenia. Schizophrenia research. vol 89. issue 1-3. 2007-04-03. PMID:17071057. |
in this study, the total volume and shape of several basal ganglia structures were compared in subjects with and without schizophrenia. |
2007-04-03 |
2023-08-12 |
human |
| Daniel Mamah, Lei Wang, Deanna Barch, Gabriel A de Erausquin, Mokhtar Gado, John G Csernansk. Structural analysis of the basal ganglia in schizophrenia. Schizophrenia research. vol 89. issue 1-3. 2007-04-03. PMID:17071057. |
in conclusion, basal ganglia volumes relative to total brain volume were larger in schizophrenia subjects than healthy comparison subjects. |
2007-04-03 |
2023-08-12 |
human |
| C Mehler-Wex, P Riederer, M Gerlac. Dopaminergic dysbalance in distinct basal ganglia neurocircuits: implications for the pathophysiology of Parkinson's disease, schizophrenia and attention deficit hyperactivity disorder. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197367. |
dopaminergic dysbalance in distinct basal ganglia neurocircuits: implications for the pathophysiology of parkinson's disease, schizophrenia and attention deficit hyperactivity disorder. |
2007-03-20 |
2023-08-12 |
mouse |
| C Mehler-Wex, P Riederer, M Gerlac. Dopaminergic dysbalance in distinct basal ganglia neurocircuits: implications for the pathophysiology of Parkinson's disease, schizophrenia and attention deficit hyperactivity disorder. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197367. |
in this paper we discuss recent evidence indicating that a dopamine-induced dysbalance of basal ganglia neurocircuitries may be an important pathophysiological component in pd, schizophrenia and adhd. |
2007-03-20 |
2023-08-12 |
mouse |
| Dietmar Spengler, Peter Trillenberg, Andreas Sprenger, Matthias Nagel, Andreas Kordon, Klaus Junghanns, Wolfgang Heide, Volker Arolt, Fritz Hohagen, Rebekka Lence. Evidence from increased anticipation of predictive saccades for a dysfunction of fronto-striatal circuits in obsessive-compulsive disorder. Psychiatry research. vol 143. issue 1. 2006-11-09. PMID:16730377. |
patients with ocd and schizophrenia revealed different patterns of oculomotor impairment: whereas increased anticipation of predictive saccades provides evidence for a dysfunction of the circuit between the frontal eye field and the basal ganglia in both groups, results from the antisaccade task imply additional deficits involving the dorsolateral prefrontal cortex in schizophrenic patients. |
2006-11-09 |
2023-08-12 |
human |
| Glenn Laywer, Håkan Nyman, Ingrid Agartz, Stefan Arnborg, Erik G Jönsson, Göran C Sedvall, Håkan Hal. Morphological correlates to cognitive dysfunction in schizophrenia as studied with Bayesian regression. BMC psychiatry. vol 6. 2006-10-24. PMID:16901336. |
relationships between cognitive deficits and brain morphological changes observed in schizophrenia are alternately explained by less gray matter in the brain cerebral cortex, by alterations in neural circuitry involving the basal ganglia, and by alteration in cerebellar structures and related neural circuitry. |
2006-10-24 |
2023-08-12 |
Not clear |
| Bangalore N Gangadhar, Peruvamba N Jayakumar, Ganesan Venkatasubramanian, Nimmagadda Janakiramaiah, Matcheri S Keshava. Developmental reflexes and 31P Magnetic Resonance Spectroscopy of basal ganglia in antipsychotic-naive schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 5. 2006-08-18. PMID:16569471. |
developmental reflexes and 31p magnetic resonance spectroscopy of basal ganglia in antipsychotic-naive schizophrenia. |
2006-08-18 |
2023-08-12 |
human |
| Bangalore N Gangadhar, Peruvamba N Jayakumar, Ganesan Venkatasubramanian, Nimmagadda Janakiramaiah, Matcheri S Keshava. Developmental reflexes and 31P Magnetic Resonance Spectroscopy of basal ganglia in antipsychotic-naive schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 5. 2006-08-18. PMID:16569471. |
the study examined the high energy-phosphate metabolism of basal ganglia in antipsychotic-naive schizophrenia patients with and without developmental reflexes in comparison to healthy subjects. |
2006-08-18 |
2023-08-12 |
human |
| Bangalore N Gangadhar, Peruvamba N Jayakumar, Ganesan Venkatasubramanian, Nimmagadda Janakiramaiah, Matcheri S Keshava. Developmental reflexes and 31P Magnetic Resonance Spectroscopy of basal ganglia in antipsychotic-naive schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 30. issue 5. 2006-08-18. PMID:16569471. |
schizophrenia patients with developmental reflexes had the lowest pcr/total atp ratio in basal ganglia indicating more severe metabolic abnormality. |
2006-08-18 |
2023-08-12 |
human |