All Relations between Schizophrenia and Risperidone
Publication |
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Publish Date |
Extraction Date |
Species |
J F Castelão, L Ferreira, Y G Gelders, S L Heyle. The efficacy of the D2 and 5-HT2 antagonist risperidone (R 64,766) in the treatment of chronic psychosis. An open dose-finding study. Schizophrenia research. vol 2. issue 4-5. 1991-03-08. PMID:2484825. |
after a wash-out period of 1 week, 20 patients suffering from schizophrenia were treated for 4 weeks in an open dose-finding study with a new serotonin-dopamine antagonist risperidone. |
1991-03-08 |
2023-08-11 |
Not clear |
C J Niemegeers, F Awouters, P A Jansse. [Serotonin antagonism involved in the antipsychotic effect. Confirmation with ritanserine and risperidone]. L'Encephale. vol 16. issue 2. 1990-07-18. PMID:1693560. |
at doses of 5 mg daily risperidone acts on both negative and positive symptoms of schizophrenia in the virtual absence of eps. |
1990-07-18 |
2023-08-11 |
Not clear |
T F Meert, P de Haes, P A Jansse. Risperidone (R 64 766), a potent and complete LSD antagonist in drug discrimination by rats. Psychopharmacology. vol 97. issue 2. 1989-07-03. PMID:2471220. |
the potential clinical effect of risperidone in the positive and negative symptoms of schizophrenia is discussed. |
1989-07-03 |
2023-08-11 |
rat |
P A Janssen, C J Niemegeers, F Awouters, K H Schellekens, A A Megens, T F Meer. Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties. The Journal of pharmacology and experimental therapeutics. vol 244. issue 2. 1988-04-12. PMID:2450200. |
the first clinical studies indicate that two additional therapeutic targets, which are not reached with classical neuroleptics, may be obtained with risperidone in the monotherapy of schizophrenia and related disorders: very important contact and mood-elevating properties and extrapyramidal symptoms-free maintenance therapy. |
1988-04-12 |
2023-08-11 |
rat |