| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A A Cardon. Risperidone: review and assessment of its role in the treatment of schizophrenia. The Annals of pharmacotherapy. vol 29. issue 6. 1995-10-12. PMID:7545034. |
risperidone: review and assessment of its role in the treatment of schizophrenia. |
1995-10-12 |
2023-08-12 |
Not clear |
| A A Cardon. Risperidone: review and assessment of its role in the treatment of schizophrenia. The Annals of pharmacotherapy. vol 29. issue 6. 1995-10-12. PMID:7545034. |
to review pharmacologic, pharmacokinetic, therapeutic, and safety information for the antipsychotic agent risperidone and to evaluate its place in the treatment of schizophrenia. |
1995-10-12 |
2023-08-12 |
Not clear |
| F M Jacobse. Risperidone in the treatment of affective illness and obsessive-compulsive disorder. The Journal of clinical psychiatry. vol 56. issue 9. 1995-10-11. PMID:7545159. |
compared with traditional dopamine-blocking neuroleptics, risperidone is more effective in treating negative symptoms of schizophrenia and may be less likely to cause extrapyramidal symptoms or tardive dyskinesia. |
1995-10-11 |
2023-08-12 |
Not clear |
| J Peusken. Risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multi-centre, double-blind, parallel-group study versus haloperidol. Risperidone Study Group. The British journal of psychiatry : the journal of mental science. vol 166. issue 6. 1995-10-10. PMID:7545060. |
risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multi-centre, double-blind, parallel-group study versus haloperidol. |
1995-10-10 |
2023-08-12 |
Not clear |
| D Shore, S Matthews, J Cott, J A Lieberma. Clinical implications of clozapine discontinuation: report of an NIMH workshop. Schizophrenia bulletin. vol 21. issue 2. 1995-09-07. PMID:7543218. |
in september 1994, the national institute of mental health convened a group of scientists to discuss the clinical effects of rapid clozapine discontinuation, especially in light of the introduction of risperidone for the treatment of schizophrenia. |
1995-09-07 |
2023-08-12 |
Not clear |
| T B Tanner, R Ganguli, R Reddy, M Allen, K Fiel. Risperidone for treatment-refractory schizophrenia. The American journal of psychiatry. vol 152. issue 8. 1995-08-31. PMID:7542836. |
risperidone for treatment-refractory schizophrenia. |
1995-08-31 |
2023-08-12 |
Not clear |
| H He, J S Richardso. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7542676. |
in clinical trials with chronic schizophrenia patients, risperidone has an overall therapeutic activity comparable with that of haloperidol, but at doses that produce similar improvements in the positive symptoms of schizophrenia, risperidone has a greater effect on the negative symptoms and produces less extrapyramidal side effects than does haloperidol. |
1995-08-30 |
2023-08-12 |
human |
| H He, J S Richardso. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7542676. |
although risperidone is effective in acute schizophrenia and in non-treatment-resistant schizophrenics, studies adequately comparing risperidone with clozapine in treatment-resistant schizophrenic patients remain to be published. |
1995-08-30 |
2023-08-12 |
human |
| M O Huttunen, T Piepponen, H Rantanen, I Larmo, R Nyholm, V Raitasu. Risperidone versus zuclopenthixol in the treatment of acute schizophrenic episodes: a double-blind parallel-group trial. Acta psychiatrica Scandinavica. vol 91. issue 4. 1995-08-30. PMID:7542829. |
a double-blind, randomized, multi-center, parallel-group study was conducted in finland to compare the efficacy and safety of risperidone with zuclopenthixol in patients with acute exacerbations of schizophrenia or schizophreniform disorder. |
1995-08-30 |
2023-08-12 |
Not clear |
| P L Pric. Risperidone for the treatment of schizophrenia: does it have a niche? South Dakota journal of medicine. vol 48. issue 5. 1995-08-07. PMID:7541553. |
risperidone for the treatment of schizophrenia: does it have a niche? |
1995-08-07 |
2023-08-12 |
Not clear |
| H J Möller, H Müller, R L Borison, N R Schooler, G Chouinar. A path-analytical approach to differentiate between direct and indirect drug effects on negative symptoms in schizophrenic patients. A re-evaluation of the North American risperidone study. European archives of psychiatry and clinical neuroscience. vol 245. issue 1. 1995-07-27. PMID:7540426. |
the hypothesis that differences in drug effects of risperidone and haloperidol on negative symptoms in schizophrenia are secondary to effects on positive, extrapyramidal, and depressive symptoms was investigated by means of an analysis of the data from the usa-canada risperidone double-blind randomized clinical trial of 523 chronic schizophrenic patients. |
1995-07-27 |
2023-08-12 |
Not clear |
| H C Sternlicht, S R Well. Risperidone in childhood schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry. vol 34. issue 5. 1995-07-10. PMID:7539785. |
risperidone in childhood schizophrenia. |
1995-07-10 |
2023-08-12 |
Not clear |
| V A Curtis, R W Kerwi. A risk-benefit assessment of risperidone in schizophrenia. Drug safety. vol 12. issue 2. 1995-06-30. PMID:7539272. |
a risk-benefit assessment of risperidone in schizophrenia. |
1995-06-30 |
2023-08-12 |
Not clear |
| N L Keltne. Risperidone: the search for a better antipsychotic. Perspectives in psychiatric care. vol 31. issue 1. 1995-06-29. PMID:7539123. |
first, risperidone is as effective as traditional antipsychotics for treating schizophrenia and perhaps more effective for treating refractory schizophrenia. |
1995-06-29 |
2023-08-12 |
Not clear |
| N L Keltne. Risperidone: the search for a better antipsychotic. Perspectives in psychiatric care. vol 31. issue 1. 1995-06-29. PMID:7539123. |
second, and related to the first point, risperidone is effective in the treatment of the negative symptoms of schizophrenia. |
1995-06-29 |
2023-08-12 |
Not clear |
| L Farde, S Nyberg, G Oxenstierna, Y Nakashima, C Halldin, B Ericsso. Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537284. |
four patients with acute exacerbation of schizophrenia were examined by pet after 4 weeks of treatment with risperidone, 6 mg daily. |
1995-05-31 |
2023-08-12 |
Not clear |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
this study compares the antipsychotic efficacy and the tolerability of risperidone and clozapine in patients with schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| E Klieser, E Lehmann, E Kinzler, C Wurthmann, K Heinric. Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7537287. |
the results suggest that risperidone is at least as effective as an antipsychotic as clozapine, providing a valuable new approach for the treatment of schizophrenia. |
1995-05-31 |
2023-08-12 |
Not clear |
| M Huttune. The evolution of the serotonin-dopamine antagonist concept. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7730499. |
risperidone has efficacy against both the positive and negative symptoms of schizophrenia and has a low tendency to produce eps. |
1995-05-31 |
2023-08-12 |
Not clear |