| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carolyn Beth McNabb, Frederick Sundram, Ian Soosay, Robert R Kydd, Bruce Roy Russel. Increased sensorimotor network connectivity associated with clozapine eligibility in people with schizophrenia. Psychiatry research. Neuroimaging. vol 275. 2019-04-01. PMID:29650266. |
increased sensorimotor network connectivity associated with clozapine eligibility in people with schizophrenia. |
2019-04-01 |
2023-08-13 |
Not clear |
| Carolyn Beth McNabb, Frederick Sundram, Ian Soosay, Robert R Kydd, Bruce Roy Russel. Increased sensorimotor network connectivity associated with clozapine eligibility in people with schizophrenia. Psychiatry research. Neuroimaging. vol 275. 2019-04-01. PMID:29650266. |
these data reveal differences in functional connectivity between flr and those eligible for clozapine and suggest that greater connectivity between the smn and precuneus may be indicative of treatment resistance in people with schizophrenia. |
2019-04-01 |
2023-08-13 |
Not clear |
| Mario de la Fuente Revenga, Daisuke Ibi, Justin M Saunders, Travis Cuddy, Maryum K Ijaz, Rudy Toneatti, Mitsumasa Kurita, Terrell Holloway, Li Shen, Jeremy Seto, Mikhail G Dozmorov, Javier González-Maes. HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice. Neuroscience. vol 388. 2019-03-29. PMID:30025863. |
antipsychotic drugs, including both typical such as haloperidol and atypical such as clozapine, remain the current standard for schizophrenia treatment. |
2019-03-29 |
2023-08-13 |
mouse |
| Parita Shah, Yusuke Iwata, Eric Plitman, Eric E Brown, Fernando Caravaggio, Julia Kim, Shinichiro Nakajima, Margaret Hahn, Gary Remington, Philip Gerretsen, Ariel Graff-Guerrer. The impact of delay in clozapine initiation on treatment outcomes in patients with treatment-resistant schizophrenia: A systematic review. Psychiatry research. vol 268. 2019-03-26. PMID:30015109. |
the impact of delay in clozapine initiation on treatment outcomes in patients with treatment-resistant schizophrenia: a systematic review. |
2019-03-26 |
2023-08-13 |
Not clear |
| Parita Shah, Yusuke Iwata, Eric Plitman, Eric E Brown, Fernando Caravaggio, Julia Kim, Shinichiro Nakajima, Margaret Hahn, Gary Remington, Philip Gerretsen, Ariel Graff-Guerrer. The impact of delay in clozapine initiation on treatment outcomes in patients with treatment-resistant schizophrenia: A systematic review. Psychiatry research. vol 268. 2019-03-26. PMID:30015109. |
approximately one-third of patients with schizophrenia have treatment-resistant schizophrenia (tr-scz), which is a condition characterized by suboptimal response to antipsychotics other than clozapine. |
2019-03-26 |
2023-08-13 |
Not clear |
| Heidi Taipale, Juha Mehtälä, Antti Tanskanen, Jari Tiihone. Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up. Schizophrenia bulletin. vol 44. issue 6. 2019-03-19. PMID:29272458. |
clozapine and lais are the most effective treatments in preventing psychiatric and all-cause hospitalization among chronic and first-episode patients with schizophrenia. |
2019-03-19 |
2023-08-13 |
Not clear |
| H C van Mierlo, C D Schubart, N M S Golüke, K M Bessembinders, J K Tijdin. [Acute dystonia in a patient with an elevated clozapine level due to an infection]. Tijdschrift voor psychiatrie. vol 60. issue 12. 2019-03-18. PMID:30536298. |
we describe the case of a 75-year-old patient with late-onset schizophrenia who used clozapine. |
2019-03-18 |
2023-08-13 |
Not clear |
| Ryo Okubo, Naoki Hashimoto, Mami Kusachi, Hisashi Narita, Ichiro Kusum. [A Case of Dilated Cardiomyopathy after 17 Years of Clozapine Treatment]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 118. issue 10. 2019-03-15. PMID:30620827. |
a 43-year-old male with a 24-year history of schizophrenia was treated with clozapine (600 mg/day) for 17 years. |
2019-03-15 |
2023-08-13 |
Not clear |
| Samantha A Hollingworth, Karl Winckel, Nargess Saiepour, Amanda J Wheeler, Nicholas Myles, Dan Siskin. Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014. Psychopharmacology. vol 235. issue 7. 2019-03-13. PMID:29589067. |
clozapine is the gold-standard medicine for treating refractory schizophrenia but there are some notable serious adverse events (ae). |
2019-03-13 |
2023-08-13 |
Not clear |
| Oddur Ingimarsson, James H MacCabe, Engilbert Sigurdsso. Constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in Iceland. Nordic journal of psychiatry. vol 72. issue 7. 2019-03-13. PMID:30348045. |
constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in iceland. |
2019-03-13 |
2023-08-13 |
Not clear |
| Oddur Ingimarsson, James H MacCabe, Engilbert Sigurdsso. Constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in Iceland. Nordic journal of psychiatry. vol 72. issue 7. 2019-03-13. PMID:30348045. |
purpose of the article: clozapine is the only evidence based treatment for treatment-resistant schizophrenia. |
2019-03-13 |
2023-08-13 |
Not clear |
| Oddur Ingimarsson, James H MacCabe, Engilbert Sigurdsso. Constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in Iceland. Nordic journal of psychiatry. vol 72. issue 7. 2019-03-13. PMID:30348045. |
the aims of this study are to describe the prevalence of constipation and ileus during clozapine treatment of patients with schizophrenia in iceland and to assess the concomitant use of medication that can cause constipation, and laxatives used to treat constipation. |
2019-03-13 |
2023-08-13 |
Not clear |
| Kevin J Li, Ronald J Gurrera, Lynn E Delis. Potentially fatal outcomes associated with clozapine. Schizophrenia research. vol 199. 2019-03-11. PMID:29503232. |
clozapine has been shown to be the most efficacious therapy for treatment resistant schizophrenia, estimated at one third of all schizophrenia cases. |
2019-03-11 |
2023-08-13 |
Not clear |
| Kevin J Li, Ronald J Gurrera, Lynn E Delis. Potentially fatal outcomes associated with clozapine. Schizophrenia research. vol 199. 2019-03-11. PMID:29503232. |
here we present a case of a 62-year-old man with chronic paranoid schizophrenia refractory to numerous antipsychotics who was started on clozapine therapy during an acute inpatient psychiatric admission. |
2019-03-11 |
2023-08-13 |
Not clear |
| Kristen Thien, Meghan Bowtell, Scott Eaton, Melissa Bardell-Williams, Linglee Downey, Aswin Ratheesh, Patrick McGorry, Brian O'Donoghu. Clozapine use in early psychosis. Schizophrenia research. vol 199. 2019-03-11. PMID:29525463. |
the superior efficacy of clozapine in treatment resistant schizophrenia has been clearly demonstrated, yet there are often delays in the commencement of clozapine. |
2019-03-11 |
2023-08-13 |
Not clear |
| Cristian Mena, Alfonso Gonzalez-Valderrama, Barbara Iruretagoyena, Juan Undurraga, Nicolas A Crossle. Early treatment resistance in a Latin-American cohort of patients with schizophrenia. Schizophrenia research. vol 199. 2019-03-11. PMID:29526456. |
we here present an analysis of clozapine prescription patterns, used as a real-world proxy marker for treatment-resistance, in a cohort of 1195 patients with schizophrenia from a latin-american cohort, to explore the timing of emergence of treatment resistance and possible subgroup differences. |
2019-03-11 |
2023-08-13 |
Not clear |
| Beatriz Rebollo, Maria Perez-Zabalza, Marcel Ruiz-Mejias, Lorena Perez-Mendez, Maria V Sanchez-Vive. Beta and Gamma Oscillations in Prefrontal Cortex During NMDA Hypofunction: An In Vitro Model of Schizophrenia Features. Neuroscience. vol 383. 2019-03-07. PMID:29723576. |
the observed action of clozapine decreasing hypersynchronization in the local circuit may be one of the mechanisms of action of clozapine in preventing schizophrenia symptoms derived from nmda hypofunction. |
2019-03-07 |
2023-08-13 |
Not clear |
| Vincenzo Monda, Monica Salerno, Francesco Sessa, Renato Bernardini, Anna Valenzano, Gabriella Marsala, Christian Zammit, Roberto Avola, Marco Carotenuto, Giovanni Messina, Antonietta Messin. Functional Changes of Orexinergic Reaction to Psychoactive Substances. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29307079. |
antipsychotic drugs are used often to treat several psychiatric disorders, including schizophrenia and bipolar disorder however, antipsychotic drugs prescription, particularly the second-generation ones (sgas), such as clozapine and olanzapine, is related to a considerable weight gain which usually leads to obesity. |
2019-02-26 |
2023-08-13 |
human |
| Tarun Bastiampillai, Olivia Tonnu, Prashant Tibrewal, Rohan Dhillo. Why not clozapine for the patient with schizophrenia at risk of suicide? Asian journal of psychiatry. vol 26. 2019-02-25. PMID:28483094. |
why not clozapine for the patient with schizophrenia at risk of suicide? |
2019-02-25 |
2023-08-13 |
Not clear |
| A Alachkar, L Wang, R Yoshimura, A R Hamzeh, Z Wang, N Sanathara, S M Lee, X Xu, G W Abbott, O Civell. Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits. Molecular psychiatry. vol 23. issue 2. 2019-02-15. PMID:28809400. |
finally, therapeutic actions of typical (haloperidol) and atypical (clozapine) antipsychotics in met mice mimicked effects in human schizophrenia patients. |
2019-02-15 |
2023-08-13 |
mouse |