| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Liu, Yin Luo, Guofu Zhang, Chunhui Jin, Zhenhe Zhou, Zaohuo Cheng, Guozhen Yua. Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment. Oncotarget. vol 8. issue 49. 2019-11-20. PMID:29156812. |
correlation of drd2 mrna expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment. |
2019-11-20 |
2023-08-13 |
Not clear |
| Liang Liu, Yin Luo, Guofu Zhang, Chunhui Jin, Zhenhe Zhou, Zaohuo Cheng, Guozhen Yua. Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment. Oncotarget. vol 8. issue 49. 2019-11-20. PMID:29156812. |
this study analyzed the relationship of deficit syndrome severity with the mrna levels of members of signaling pathways that associate with the pathophysiology of schizophrenia, including the dopamine d2 receptor (drd2), protein kinase b (akt1), and phosphoinositide-3 kinase (pi3kcb), in peripheral blood leukocytes (pbls) of 20 healthy controls and 19 chronic schizophrenia patients with long-term clozapine treatment. |
2019-11-20 |
2023-08-13 |
Not clear |
| Liang Liu, Yin Luo, Guofu Zhang, Chunhui Jin, Zhenhe Zhou, Zaohuo Cheng, Guozhen Yua. Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment. Oncotarget. vol 8. issue 49. 2019-11-20. PMID:29156812. |
in conclusion, a correlation was observed between increased deficit syndrome severity and elevated expression levels of drd2 in pbls of chronic schizophrenia patients receiving long-term clozapine treatment. |
2019-11-20 |
2023-08-13 |
Not clear |
| Dorgival Caetano, Irina Piatko. Ultrarapid clozapine metabolism and CYP2D6 gene duplication in a patient with schizophrenia. Personalized medicine. vol 13. issue 2. 2019-11-20. PMID:29749897. |
ultrarapid clozapine metabolism and cyp2d6 gene duplication in a patient with schizophrenia. |
2019-11-20 |
2023-08-13 |
Not clear |
| David Sarfati, Jonathan Lai, Howard C Margoles. Methylphenidate as Treatment for Clozapine-Induced Sedation in Patients with Treatment-Resistant Schizophrenia. Clinical schizophrenia & related psychoses. 2019-11-20. PMID:29944412. |
treatment-resistant schizophrenia patients frequently need to be managed with clozapine. |
2019-11-20 |
2023-08-13 |
Not clear |
| Massimiliano Buoli, Chiara Rovera, Cecilia Maria Esposito, Silvia Grassi, Wiepke Cahn, A Carlo Altamur. THE USE OF LONG-ACTING ANTIPSYCHOTICS FOR THE MANAGEMENT OF AGGRESSIVENESS IN SCHIZOPHRENIA: A CLINICAL OVERVIEW. Clinical schizophrenia & related psychoses. 2019-11-20. PMID:29944415. |
with oral clozapine and aripiprazole depot) are needed to assess the real clinical advantage of the use of depot antipsychotic versus oral alternatives for the prevention of violent behaviour in schizophrenia. |
2019-11-20 |
2023-08-13 |
human |
| Neelava Sengupta, Carolyn B McNabb, Nikola Kasabov, Bruce R Russel. Integrating Space, Time, and Orientation in Spiking Neural Networks: A Case Study on Multimodal Brain Data Modeling. IEEE transactions on neural networks and learning systems. vol 29. issue 11. 2019-11-20. PMID:29994642. |
furthermore, a case study is presented, which aims to build a computational model that discriminates between people with schizophrenia who respond or do not respond to monotherapy with the antipsychotic clozapine. |
2019-11-20 |
2023-08-13 |
Not clear |
| Anwar Ul-Haq, Edmond Hollan. Pulmonary embolism secondary to clozapine therapy. Irish journal of psychological medicine. vol 26. issue 3. 2019-11-20. PMID:30282311. |
clozapine is an atypical antipsychotic indicated for paranoid schizophrenia (treatment resistant type). |
2019-11-20 |
2023-08-13 |
Not clear |
| Sarah E Prasad, Harry G Kenned. Pseudophaeochromocytoma associated with clozapine treatment. Irish journal of psychological medicine. vol 20. issue 4. 2019-11-20. PMID:30308722. |
we describe a 44 year old man with treatment resistant schizophrenia who developed pseudophaeochromocytoma on clozapine with high blood pressure, tachycardia and elevated 24 hour urinary catecholamines. |
2019-11-20 |
2023-08-13 |
Not clear |
| Padraig Wright, Luke O'Flahert. Antipsychotic drugs: atypical advantages and typical disadvantages. Irish journal of psychological medicine. vol 20. issue 1. 2019-11-20. PMID:30440229. |
clozapine is marketed for patients unresponsive to, or intolerant of, other antipsychotic drugs and must thus be regarded as a second line treatment for schizophrenia. |
2019-11-20 |
2023-08-13 |
Not clear |
| Alex Till, Ed Silv. A case report of the successful administration of clozapine in the face of myocardial infarction, pulmonary embolism and hyperlipidaemia resulting in the termination of long-term seclusion. BMC psychiatry. vol 19. issue 1. 2019-11-19. PMID:30674292. |
clozapine has the greatest efficacy for treatment resistant schizophrenia (trs) but the greatest negative impact on cardiometabolic health. |
2019-11-19 |
2023-08-13 |
Not clear |
| Lee-Hou Tsai, Jeng-Wen Li. Use of clozapine for resolving lamotrigine-induced skin lesions caused by schizophrenia treatment. Psychiatria Danubina. vol 31. issue 3. 2019-11-18. PMID:31596832. |
use of clozapine for resolving lamotrigine-induced skin lesions caused by schizophrenia treatment. |
2019-11-18 |
2023-08-13 |
Not clear |
| Worrawat Chanpattana, William V McCal. Commentary on Braga et al: The Potential of Large Simple Trials to Determine the Real-World Effectiveness of Combined Electroconvulsive Therapy and Antipsychotics in Treating Patients With Treatment-Resistant Schizophrenia. The journal of ECT. vol 35. issue 3. 2019-11-15. PMID:30870262. |
this commentary reflects upon the study of braga et al of open-label continuation electroconvulsive therapy (ect) plus clozapine in treatment-resistant schizophrenia (trs), as reported in this issue of the journal of ect. |
2019-11-15 |
2023-08-13 |
Not clear |
| Vivekananda Rachamallu, Benjamin W Elberson, Emily Vutam, Manish Aliget. Off-Label Use of Clozapine in Children and Adolescents-A Literature Review. American journal of therapeutics. vol 26. issue 3. 2019-11-15. PMID:31082865. |
clozapine is a second-generation antipsychotic typically used for refractory schizophrenia or otherwise psychotic pathology. |
2019-11-15 |
2023-08-13 |
Not clear |
| L Mizera, K Klingel, M Gawaz, S Greulic. [Fatigue, breathlessness and chest pain in a 31-year-old man with schizoaffective disorder]. Der Internist. vol 60. issue 11. 2019-11-05. PMID:31501912. |
clozapine is an alternative antipsychotic medication used to control symptoms of schizophrenia and to reduce risks of suicidal behavior in patients who did not adequately respond to standard medication. |
2019-11-05 |
2023-08-13 |
Not clear |
| Ilijana Babic, Ashleigh Gorak, Martin Engel, Dominic Sellers, Paul Else, Ashleigh L Osborne, Nagesh Pai, Xu-Feng Huang, Jessica Nealon, Katrina Weston-Gree. Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats. Journal of psychopharmacology (Oxford, England). vol 32. issue 5. 2019-11-04. PMID:29493378. |
antipsychotic drugs (apds), olanzapine and clozapine, do not effectively address the cognitive symptoms of schizophrenia and can cause serious metabolic side-effects. |
2019-11-04 |
2023-08-13 |
rat |
| Hai-Quyen Tran, Se J Park, Eun-Joo Shin, The-Vinh Tran, Naveen Sharma, Yu J Lee, Ji H Jeong, Choon-Gon Jang, Dae-Joong Kim, Toshitaka Nabeshima, Hyoung-Chun Ki. Clozapine attenuates mitochondrial burdens and abnormal behaviors elicited by phencyclidine in mice via inhibition of p47 Journal of psychopharmacology (Oxford, England). vol 32. issue 11. 2019-10-31. PMID:30207504. |
clozapine attenuates mitochondrial burdens and abnormal behaviors elicited by phencyclidine in mice via inhibition of p47 oxidative stress and mitochondrial dysfunction have been implicated in the pathophysiology of schizophrenia. |
2019-10-31 |
2023-08-13 |
mouse |
| D Siskind, T Reddel, J H MacCabe, S Kisel. The impact of clozapine initiation and cessation on psychiatric hospital admissions and bed days: a mirror image cohort study. Psychopharmacology. vol 236. issue 6. 2019-10-28. PMID:30715572. |
clozapine is the most effective medication for the positive symptoms of treatment-refractory schizophrenia. |
2019-10-28 |
2023-08-13 |
Not clear |
| Xiaoduo Fan, Paul Copeland, Shukair Nawras, Amy Harrington, Oliver Freudenreich, Donald C Goff, David C Henderso. Adjunctive telmisartan treatment on body metabolism in clozapine or olanzapine treated patients with schizophrenia: a randomized, double blind, placebo controlled trial. Psychopharmacology. vol 236. issue 6. 2019-10-28. PMID:30747254. |
adjunctive telmisartan treatment on body metabolism in clozapine or olanzapine treated patients with schizophrenia: a randomized, double blind, placebo controlled trial. |
2019-10-28 |
2023-08-13 |
Not clear |
| Alina Wilkowska, Mariusz S Wiglusz, Wiesław J Cubał. Clozapine: promising treatment for suicidality in bipolar disorder. Psychiatria Danubina. vol 31. issue Suppl 3. 2019-10-23. PMID:31488793. |
there is evidence for anti-suicidal effect of clozapine in schizophrenia. |
2019-10-23 |
2023-08-13 |
Not clear |