| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kohei Kitagawa, Shusuke Uekusa, Yuki Hanai, Itsuki Kimura, Masaru Tsukahara, Azusa Kagawa, Kenji Sasaoka, Yui Sakishiro, Ayaka Miyake, Yuki Watanabe, Daiki Baba, Masafumi Kodama, Yoshiki Kishi, Norihito Yamada, Takashi Yoshio, Kazuhiro Matsu. Changes in psychopharmacotherapy for patients with schizophrenia in a psychiatric institution in Japan: A 12-year prescription survey pre- and post-introduction of clozapine. Asian journal of psychiatry. vol 96. 2024-04-19. PMID:38640549. |
the increase in clozapine prescription has contributed to an increased rate of antipsychotic monotherapy and a decreased rate of polypharmacy, promoting the optimization of schizophrenia medication. |
2024-04-19 |
2024-04-22 |
Not clear |
| Kohei Kitagawa, Shusuke Uekusa, Yuki Hanai, Itsuki Kimura, Masaru Tsukahara, Azusa Kagawa, Kenji Sasaoka, Yui Sakishiro, Ayaka Miyake, Yuki Watanabe, Daiki Baba, Masafumi Kodama, Yoshiki Kishi, Norihito Yamada, Takashi Yoshio, Kazuhiro Matsu. Changes in psychopharmacotherapy for patients with schizophrenia in a psychiatric institution in Japan: A 12-year prescription survey pre- and post-introduction of clozapine. Asian journal of psychiatry. vol 96. 2024-04-19. PMID:38640549. |
clozapine therapy should be further promoted in japan to reduce treatment-resistant schizophrenia due to polypharmacy as much as possible. |
2024-04-19 |
2024-04-22 |
Not clear |
| Hasan Çağın Lenk, Robert Løvsletten Smith, Kevin S O'Connell, Ole A Andreassen, Espen Molde. Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data. CNS drugs. 2024-04-18. PMID:38635089. |
adequate antipsychotic treatment intensity is required before diagnosing resistant schizophrenia and initiating clozapine treatment. |
2024-04-18 |
2024-04-20 |
Not clear |
| Merve Direktor, Peter Gass, Dragos Int. Understanding the therapeutic action of antipsychotics: from molecular to cellular targets with focus on the islands of Calleja. The international journal of neuropsychopharmacology. 2024-04-17. PMID:38629703. |
here we discuss results suggesting a main role of the islands of calleja, still poorly studied gabaergic granule cell clusters in the ventral striatum, as cellular targets of several innovative atypical antipsychotics (clozapine, cariprazine and xanomeline/emraclidine) effective in treating also negative symptoms of schizophrenia. |
2024-04-17 |
2024-04-19 |
Not clear |
| Archana Mishra, Rituparna Maiti, Biswa Ranjan Mishra, Anand Srinivasa. Augmentation Strategies for Partial or Non-responders to Clozapine in Patients with Schizophrenia: A Bayesian Network Meta-analysis of Randomized Controlled Trials. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 22. issue 2. 2024-04-16. PMID:38627071. |
augmentation strategies for partial or non-responders to clozapine in patients with schizophrenia: a bayesian network meta-analysis of randomized controlled trials. |
2024-04-16 |
2024-04-19 |
Not clear |
| Vicent Llorca-Bofí, Miquel Bioque, Santiago Madero, Andrea Mallorquí, Cristina Oliveira, Marina Garriga, Eduard Parellada, Clemente García-Riz. Blood Cell Count Ratios at Baseline are Associated with Initial Clinical Response to Clozapine in Treatment-Resistant, Clozapine-Naïve, Schizophrenia-Spectrum Disorder. Pharmacopsychiatry. 2024-04-15. PMID:38621701. |
clozapine is the recommended treatment for managing treatment-resistant schizophrenia (trs), and immunological mechanisms may be involved in its unique antipsychotic efficacy. |
2024-04-15 |
2024-04-18 |
Not clear |
| Javeria Sahib Din, Ernesto Navarro Garcia, Hiba Al-Rubaye, Carlos Julia. Knee Buckling as an Atypical Adverse Effect of Clozapine: A Case Report. Cureus. vol 16. issue 3. 2024-04-10. PMID:38595866. |
clozapine has become a widely popular and effective medication in the treatment of refractory schizophrenia and refractory bipolar disorder. |
2024-04-10 |
2024-04-12 |
Not clear |
| Nuree Kang, Hee-Soo Yoon, Se Hyun Kim, Jae Hoon Jeong, Minah Kim, Jun Soo Kwo. Comparative Study of the Efficacy and Side Effects of Brand-Name and Generic Clozapine for Long-Term Maintenance Treatment Among Korean Patients With Schizophrenia: A Retrospective Naturalistic Mirror-Image Study. Psychiatry investigation. vol 21. issue 3. 2024-04-03. PMID:38569589. |
comparative study of the efficacy and side effects of brand-name and generic clozapine for long-term maintenance treatment among korean patients with schizophrenia: a retrospective naturalistic mirror-image study. |
2024-04-03 |
2024-04-06 |
Not clear |
| Nuree Kang, Hee-Soo Yoon, Se Hyun Kim, Jae Hoon Jeong, Minah Kim, Jun Soo Kwo. Comparative Study of the Efficacy and Side Effects of Brand-Name and Generic Clozapine for Long-Term Maintenance Treatment Among Korean Patients With Schizophrenia: A Retrospective Naturalistic Mirror-Image Study. Psychiatry investigation. vol 21. issue 3. 2024-04-03. PMID:38569589. |
clozapine is considered the most reliable drug for treatment-resistant schizophrenia. |
2024-04-03 |
2024-04-06 |
Not clear |
| Nuree Kang, Hee-Soo Yoon, Se Hyun Kim, Jae Hoon Jeong, Minah Kim, Jun Soo Kwo. Comparative Study of the Efficacy and Side Effects of Brand-Name and Generic Clozapine for Long-Term Maintenance Treatment Among Korean Patients With Schizophrenia: A Retrospective Naturalistic Mirror-Image Study. Psychiatry investigation. vol 21. issue 3. 2024-04-03. PMID:38569589. |
this study was performed to provide clinical information regarding the use of clozapine and to compare efficacy and tolerability when converting from the brand-name formulation (clozaril) to the generic formulation during longterm maintenance treatment among korean patients with schizophrenia. |
2024-04-03 |
2024-04-06 |
Not clear |
| Jingqi He, Jinguang Li, Yisen Wei, Zhangyin He, Junyu Liu, Ning Yuan, Risheng Zhou, Xingtao He, Honghong Ren, Lin Gu, Yanhui Liao, Xiaogang Chen, Jinsong Tan. Multiple serum anti-glutamate receptor antibody levels in clozapine-treated/naïve patients with treatment-resistant schizophrenia. BMC psychiatry. vol 24. issue 1. 2024-04-02. PMID:38566016. |
glutamatergic function abnormalities have been implicated in the etiology of treatment-resistant schizophrenia (trs), and the efficacy of clozapine may be attributed to its impact on the glutamate system. |
2024-04-02 |
2024-04-05 |
Not clear |
| Justina A Warnick, Rachel I Gifeisman, Khevna P Joshi, Sophie A Roe, Rick A Hiciano, Christopher P Conroy, Sohrab Zahed. Dual Atypical Antipsychotics in Treatment-Resistant Schizophrenia: A Correctional Case Report and Review of Literature. Journal of correctional health care : the official journal of the National Commission on Correctional Health Care. 2024-04-02. PMID:38563618. |
in the correctional setting, patients with severe and persistent schizophrenia are frequently nonadherent due to lack of insight and anemic access to health care resources, specifically as these pertain to clozapine. |
2024-04-02 |
2024-04-04 |
Not clear |
| Yuichi Uwai, Tomohiro Nabekur. Relationship Between Clozapine and Non-Hematological Malignant Tumors: A Pharmacovigilance Analysis Using the FDA Adverse Event Reporting System Database. Drugs - real world outcomes. 2024-03-31. PMID:38556566. |
clozapine shows higher efficacy against treatment-resistant schizophrenia than other antipsychotics. |
2024-03-31 |
2024-04-03 |
Not clear |
| Estela Sangüesa, Emilio Fernández-Egea, Julia Concha, Cristina B García, María Pilar Ribat. Impact of Pharmacogenetic Testing on Clozapine Treatment Efficacy in Patients with Treatment-Resistant Schizophrenia. Biomedicines. vol 12. issue 3. 2024-03-28. PMID:38540209. |
impact of pharmacogenetic testing on clozapine treatment efficacy in patients with treatment-resistant schizophrenia. |
2024-03-28 |
2024-03-30 |
Not clear |
| Estela Sangüesa, Emilio Fernández-Egea, Julia Concha, Cristina B García, María Pilar Ribat. Impact of Pharmacogenetic Testing on Clozapine Treatment Efficacy in Patients with Treatment-Resistant Schizophrenia. Biomedicines. vol 12. issue 3. 2024-03-28. PMID:38540209. |
managing schizophrenia with clozapine poses a significant challenge due to prevalent therapeutic failures. |
2024-03-28 |
2024-03-30 |
Not clear |
| Natasha Marcella Vaselli, Stanley Du Preez, Nuwan Jasenthu Kankanamag. Clozapine-induced pneumonitis mimicking an atypical pneumonia. BMJ case reports. vol 17. issue 3. 2024-03-26. PMID:38531554. |
clozapine is an antipsychotic used for treatment-resistant schizophrenia with a significant side effect profile, including agranulocytosis, myocarditis and fever. |
2024-03-26 |
2024-03-29 |
Not clear |
| Reza Rafizadeh, Anmol Sooch, Alessia Risi, Nicoline Bihelek, Kyler Kanegawa, Alasdair M Barr, Randall F White, Christian G Schütz, Chad A Bousma. Impact of patient-specific factors on clozapine metabolism in individuals with treatment-resistant schizophrenia or schizoaffective disorder. Journal of psychopharmacology (Oxford, England). 2024-03-23. PMID:38520287. |
impact of patient-specific factors on clozapine metabolism in individuals with treatment-resistant schizophrenia or schizoaffective disorder. |
2024-03-23 |
2024-03-26 |
Not clear |
| Spenser Barry, L Fredrik Jarskog, Kai Xia, Rohit Simha Torpunuri, Xiaoyu Wu, Xiaoming Zen. Racial Disparities in Clozapine Prescription Patterns Among Patients With Schizophrenia. Psychiatric services (Washington, D.C.). 2024-03-19. PMID:38500451. |
racial disparities in clozapine prescription patterns among patients with schizophrenia. |
2024-03-19 |
2024-03-21 |
Not clear |
| Spenser Barry, L Fredrik Jarskog, Kai Xia, Rohit Simha Torpunuri, Xiaoyu Wu, Xiaoming Zen. Racial Disparities in Clozapine Prescription Patterns Among Patients With Schizophrenia. Psychiatric services (Washington, D.C.). 2024-03-19. PMID:38500451. |
previous research has suggested that demographic factors affect the likelihood of a patient with schizophrenia receiving a clozapine prescription. |
2024-03-19 |
2024-03-21 |
Not clear |
| Felipe Mendonça Rocha Barros, Arthur Cardoso Tolentino, Lais Soares Ker Marques, Leandro Xavier de Camargo Schlittler, Karina Diniz Oliveira, Paulo Dalgalarrondo, Lucas Luchesi Barnes, Amilton Dos Santos Junior, Claudio Eduardo Muller Banzat. Successful Clozapine Rechallenge After Clozapine-Induced Severe Anemia: A Case Report. Schizophrenia bulletin. 2024-03-19. PMID:38502910. |
clozapine, a second-generation antipsychotic (sga), is considered the gold standard medication to treat patients with treatment-resistant schizophrenia (trs). |
2024-03-19 |
2024-03-23 |
Not clear |