Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Amy L Gillespie, Emma M Walker, Eilis Hannon, Grant A McQueen, Kyra-Verena Sendt, Alessia Avila, John Lally, Cynthia Okhuijsen-Pfeifer, Marte van der Horst, Alkomiet Hasan, Emma L Dempster, Joe Burrage, Jan Bogers, Dan Cohen, Marco P Boks, David A Collier, Alice Egerton, Jurjen J Luykx, Jonathan Mill, James H MacCab. Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts. Translational psychiatry. vol 14. issue 1. 2024-09-28. PMID:39333502. |
the second-generation antipsychotic clozapine is used as a medication for treatment-resistant schizophrenia. |
2024-09-28 |
2024-10-01 |
Not clear |
Hasan Çağın Lenk, Elise Koch, Kevin S O'Connell, Robert Løvsletten Smith, Ibrahim A Akkouh, Srdjan Djurovic, Ole A Andreassen, Espen Molde. Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment. Human genomics. vol 18. issue 1. 2024-09-28. PMID:39334510. |
here, we conducted a genome-wide association study on patients treated with clozapine (trs) vs. risperidone (non-trs) and investigated whether single variants and/or polygenic risk score for schizophrenia are associated with trs status. |
2024-09-28 |
2024-10-01 |
Not clear |
Ruri Okubo, Motohiro Okada, Eishi Motomur. Dysfunction of the NMDA Receptor in the Pathophysiology of Schizophrenia and/or the Pathomechanisms of Treatment-Resistant Schizophrenia. Biomolecules. vol 14. issue 9. 2024-09-28. PMID:39334894. |
however, neither typical nor atypical antipsychotics, other than clozapine, have been effective in addressing negative symptoms and cognitive impairments, which are indices for the prognostic and disability outcomes of schizophrenia. |
2024-09-28 |
2024-10-01 |
Not clear |
Tambi I Isaa. Normocytic Anemia as a Side Effect of Clozapine: A Case Report. Cureus. vol 16. issue 8. 2024-09-24. PMID:39314579. |
this brief case report aims to shed light on an uncommon blood-related side effect potentially associated with clozapine use, an atypical antipsychotic primarily prescribed for treatment-resistant schizophrenia. |
2024-09-24 |
2024-09-26 |
Not clear |
Tambi I Isaa. Normocytic Anemia as a Side Effect of Clozapine: A Case Report. Cureus. vol 16. issue 8. 2024-09-24. PMID:39314579. |
a 70-year-old white male with a significant past medical history of schizophrenia controlled with clozapine was evaluated over approximately two months. |
2024-09-24 |
2024-09-26 |
Not clear |
Balazs Adam, Osama Aya. Improving the Monitoring and Management of Clozapine-Induced Gastrointestinal Hypomotility (CIGH) in Community Mental Health Services: A Quality Improvement Approach. Pharmacy (Basel, Switzerland). vol 12. issue 5. 2024-09-23. PMID:39311132. |
clozapine is the only approved antipsychotic for refractory schizophrenia to date. |
2024-09-23 |
2024-09-26 |
Not clear |
Francesca McDonagh, Anna Tumeo, Elaine K Murray, Brian Hallahan, Georgios Milioti. Complete genome of Escherichia coli sequence type 73 with acquired blaTEM-1 and high genotypic virulence load identified in human saliva. Journal of global antimicrobial resistance. 2024-09-20. PMID:39303870. |
we report the complete genome of a genomically hypervirulent e. coli st73 strain isolated from the oral cavity of a patient with a diagnosis of treatment resistant schizophrenia and receiving clozapine treatment. |
2024-09-20 |
2024-09-23 |
human |
Shunya Aoki, Katsutoshi Takada, Tatsuru Sugama, Mitsugi Kimiwada, Tatsuya Hoshino, Takaoki Kaneko, Shintaro Obata, Yasuhiro Ota, Satoshi Toishi, Kaori Koike, Hirokazu Akada, Takahisa Saiga, Shigeki Sat. Clozapine treatment of a Japanese patient during pregnancy: Effect on fetal heart rate. Neuropsychopharmacology reports. 2024-09-16. PMID:39285465. |
in this case, a 29-year-old japanese primipara with treatment-resistant schizophrenia taking clozapine 250 mg/day experienced pregnancy. |
2024-09-16 |
2024-09-19 |
Not clear |
Aykut Kul, Fatma Budak, Ahmet Cetinkaya, S Irem Kaya, Selen Al, Olcay Sagirli, Sibel A Ozka. Fabrication of a molecularly imprinted polymer-based electrochemical sensor for the selective assay of antipsychotic drug clozapine and performance comparison with LC-MS/MS. Talanta. vol 281. 2024-09-06. PMID:39241641. |
clozapine (clo) is an atypical antipsychotic drug indicated for the treatment of schizophrenia. |
2024-09-06 |
2024-09-10 |
human |
Anzejs Dmuhovskis, Maris Taub. Cariprazine and clozapine combination for the treatment of psychosis in a young, female patient with schizophrenia: a case report. Frontiers in psychiatry. vol 15. 2024-09-05. PMID:39234624. |
cariprazine and clozapine combination for the treatment of psychosis in a young, female patient with schizophrenia: a case report. |
2024-09-05 |
2024-09-08 |
Not clear |
Carlos De Las Cuevas, Victoria C de Leon, Hilario Blasco-Fontecilla, Enrique Baca-García, Marina Sagud, Emilio J Sanz, Jose de Leo. Clozapine may consistently protect from suicidal behaviors while other antipsychotics may lack a specific protective effect: a comprehensive VigiBase study interpreted in the context of the prior literature. Expert opinion on drug safety. 2024-09-03. PMID:39223773. |
in the united states clozapine was first approved for treatment-resistant schizophrenia and then for suicidality in schizophrenia psychoses. |
2024-09-03 |
2024-09-05 |
Not clear |
Chenghao Lu, Xiaoying Jin, Nannan Liu, Yanzhe Li, Yeqing Dong, Xinxu Wang, Shen Li, Jie L. The relationship of cardiovascular disease risk, clozapine antipsychotic use and cognitive function in a large Chinese schizophrenia cohort. Brain research. 2024-09-02. PMID:39222872. |
the relationship of cardiovascular disease risk, clozapine antipsychotic use and cognitive function in a large chinese schizophrenia cohort. |
2024-09-02 |
2024-09-05 |
Not clear |
Chenghao Lu, Xiaoying Jin, Nannan Liu, Yanzhe Li, Yeqing Dong, Xinxu Wang, Shen Li, Jie L. The relationship of cardiovascular disease risk, clozapine antipsychotic use and cognitive function in a large Chinese schizophrenia cohort. Brain research. 2024-09-02. PMID:39222872. |
this study explores the intricate relationship between clozapine use, cardiovascular disease (cvd) risk, and cognitive function in patients with schizophrenia (scz). |
2024-09-02 |
2024-09-05 |
Not clear |
Helio Elkis, Debora Luciana Melzer-Ribeiro, Isabel Cristina Napolitan. Response to Markota et al. "Clinical heterogeneity and ECT in patients with clozapine resistant schizophrenia" SCHRES-D-24-00481. Schizophrenia research. vol 272. 2024-08-30. PMID:39214020. |
"clinical heterogeneity and ect in patients with clozapine resistant schizophrenia" schres-d-24-00481. |
2024-08-30 |
2024-09-04 |
Not clear |
Aviv Segev, Risha Govind, Ebenezer Oloyede, Hamilton Morrin, Amelia Jewell, Rowena Jones, Laura Mangiaterra, Stefano Bonora, Ehtesham Iqbal, Robert Stewart, Matthew Broadbent, James H MacCab. Developing a validated methodology for identifying clozapine treatment periods in electronic health records. BMC psychiatry. vol 24. issue 1. 2024-08-28. PMID:39192241. |
clozapine is the only recommended antipsychotic medication for individuals diagnosed with treatment-resistant schizophrenia. |
2024-08-28 |
2024-08-30 |
Not clear |
Yanzhe Li, Minghuan Zhu, Yeqing Dong, Nannan Liu, Xinxu Wang, Bing Yang, Zezhi Li, Shen L. Immunoinflammatory features and cognitive function in treatment-resistant schizophrenia: unraveling distinct patterns in clozapine-resistant patients. European archives of psychiatry and clinical neuroscience. 2024-08-28. PMID:39196353. |
patients with treatment-resistant schizophrenia (trs), particularly those resistant to clozapine (ctrs), pose a clinical challenge due to limited response to standard antipsychotic treatments. |
2024-08-28 |
2024-08-30 |
Not clear |
Matej Markota, Paul E Croarkin, Brandon J Coombes, Melanie T Gentry, Jonathan G Leun. Clinical heterogeneity and ECT in patients with clozapine resistant schizophrenia. Schizophrenia research. vol 272. 2024-08-28. PMID:39197319. |
clinical heterogeneity and ect in patients with clozapine resistant schizophrenia. |
2024-08-28 |
2024-09-01 |
Not clear |
Yuhei Suzuki, Kenya Watanabe, Keiko Kanno-Nozaki, Sho Horikoshi, Mizue Ichinose, Yoichiro Hirata, Yuri Kobayashi, Satoshi Takeuchi, Kouichi Osonoe, Shuzo Hoshino, Itaru Miur. Factors associated with cognitive dysfunction in treatment-responsive and -resistant schizophrenia: A pilot cross-sectional study. Journal of psychiatric research. vol 178. 2024-08-20. PMID:39163661. |
we aimed to clarify the association between cognitive dysfunction and factors, such as plasma concentrations of clozapine (clz), n-desmethylclozapine (ndmc), and homovanillic acid (hva), due to differences in antipsychotic responses in patients with schizophrenia. |
2024-08-20 |
2024-08-23 |
Not clear |
Yin Cao, Qingrong Xia, Jun Liang, Jiequan Wang, Feng Shan, Biao Da. Effect of Common Cold on Serum Clozapine Concentrations in Hospitalized Patients with Schizophrenia. Neuropsychiatric disease and treatment. vol 20. 2024-08-19. PMID:39156033. |
effect of common cold on serum clozapine concentrations in hospitalized patients with schizophrenia. |
2024-08-19 |
2024-08-21 |
Not clear |
Yin Cao, Qingrong Xia, Jun Liang, Jiequan Wang, Feng Shan, Biao Da. Effect of Common Cold on Serum Clozapine Concentrations in Hospitalized Patients with Schizophrenia. Neuropsychiatric disease and treatment. vol 20. 2024-08-19. PMID:39156033. |
the present study aims to investigate the effect of common cold on the serum clozapine concentrations in hospitalized patients with schizophrenia. |
2024-08-19 |
2024-08-21 |
Not clear |