| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Grant McQueen, Kyra-Verena Sendt, Amy Gillespie, Alessia Avila, John Lally, Kalliopi Vallianatou, Nynn Chang, Diogo Ferreira, Faith Borgan, Oliver D Howes, Gareth J Barker, David J Lythgoe, James M Stone, Philip McGuire, James H MacCabe, Alice Egerto. Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia. Schizophrenia bulletin. vol 47. issue 3. 2021-11-22. PMID:33398325. |
changes in brain glutamate on switching to clozapine in treatment-resistant schizophrenia. |
2021-11-22 |
2023-08-13 |
Not clear |
| Grant McQueen, Kyra-Verena Sendt, Amy Gillespie, Alessia Avila, John Lally, Kalliopi Vallianatou, Nynn Chang, Diogo Ferreira, Faith Borgan, Oliver D Howes, Gareth J Barker, David J Lythgoe, James M Stone, Philip McGuire, James H MacCabe, Alice Egerto. Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia. Schizophrenia bulletin. vol 47. issue 3. 2021-11-22. PMID:33398325. |
it has been suggested that the antipsychotic clozapine may modulate brain glutamate, and that this effect could contribute to its efficacy in treatment-resistant schizophrenia (trs). |
2021-11-22 |
2023-08-13 |
Not clear |
| Rodolfo Furlan Damiano, Belquiz S Avrichir, Débora L Melzer-Ribeiro, Paulo Clemente Sallet, Helio Elki. Which are the best evidence-based therapeutic options for clozapine and ECT resistant schizophrenia? A case-report. Psychiatry research. vol 305. 2021-11-19. PMID:34739952. |
which are the best evidence-based therapeutic options for clozapine and ect resistant schizophrenia? |
2021-11-19 |
2023-08-13 |
Not clear |
| Rodolfo Furlan Damiano, Belquiz S Avrichir, Débora L Melzer-Ribeiro, Paulo Clemente Sallet, Helio Elki. Which are the best evidence-based therapeutic options for clozapine and ECT resistant schizophrenia? A case-report. Psychiatry research. vol 305. 2021-11-19. PMID:34739952. |
this is a case description of a patient with clozapine and ect resistance schizophrenia with several suicide attempts. |
2021-11-19 |
2023-08-13 |
Not clear |
| Christine Sahyouni, Elika Hefaz. Clozapine induced pericarditis: A case report. Psychiatry research. vol 305. 2021-11-19. PMID:34749222. |
clozapine is a second-generation antipsychotic often used for treatment-refractory schizophrenia and has many adverse effects. |
2021-11-19 |
2023-08-13 |
Not clear |
| Christine Sahyouni, Elika Hefaz. Clozapine induced pericarditis: A case report. Psychiatry research. vol 305. 2021-11-19. PMID:34749222. |
this is a case report of a 32-year old male with paranoid schizophrenia who developed pericarditis after initiation and titration of clozapine in the inpatient psychiatry unit. |
2021-11-19 |
2023-08-13 |
Not clear |
| Silviu Tomulescu, Kim Uittenhove, Reda Boukakio. Managing Recurrent Clozapine-Induced Constipation in a Patient with Resistant Schizophrenia. Case reports in psychiatry. vol 2021. 2021-11-19. PMID:34790422. |
clozapine is an effective antipsychotic for the treatment of resistant schizophrenia. |
2021-11-19 |
2023-08-13 |
Not clear |
| Ed Boai. A story of recovery from the dangers of drug use and psychosis. Journal of psychiatric and mental health nursing. vol 28. issue 6. 2021-11-18. PMID:34558150. |
: the effectiveness of clozapine for some people suffering from schizophrenia. |
2021-11-18 |
2023-08-13 |
human |
| Fitri Fareez Ramli, Adli Ali, Syed Alhafiz Syed Hashim, Yusof Kamisah, Normala Ibrahi. Reduction in Absolute Neutrophil Counts in Patient on Clozapine Infected with COVID-19. International journal of environmental research and public health. vol 18. issue 21. 2021-11-18. PMID:34769806. |
despite its severe adverse effects, such as agranulocytosis, clozapine is the primary treatment for treatment-resistant schizophrenia. |
2021-11-18 |
2023-08-13 |
Not clear |
| Masaru Nakamura, Takahiko Nagamin. Metabolic Effects of Clozapine Administration Based on Sex Differences and the Relationships Between Dosage and Prolactin Levels: An Observational Study. Clinical neuropharmacology. vol 44. issue 6. 2021-11-16. PMID:34581701. |
this study aimed to investigate the effects of clozapine treatment on metabolic and neuroendocrine parameters, and the relationships between prescribed clozapine dosage and prolactin levels that may be associated with plasma clozapine concentrations, in 24 female and 24 male japanese schizophrenia inpatients switched to clozapine. |
2021-11-16 |
2023-08-13 |
Not clear |
| Gokhan Unal, Serap Sirvanci, Feyza Ariciogl. α7 nicotinic receptor agonist and positive allosteric modulators differently improved schizophrenia-like cognitive deficits in male rats. Behavioural brain research. vol 397. 2021-11-15. PMID:33011186. |
this study comparatively investigated the effect of α7 nachr agonist (a-582941), type i pam (ccmi), type ii pam (pnu-120596), and the antipsychotic drug (clozapine) on behavioral, molecular, and immunohistochemical parameters in a subchronic mk-801 model of schizophrenia in male rats. |
2021-11-15 |
2023-08-13 |
human |
| Mina Y George, Esther T Menze, Ahmed Esmat, Mariane G Tadros, Ebtehal El-Demerdas. Naringin treatment improved main clozapine-induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis. Drug development research. vol 82. issue 7. 2021-11-15. PMID:33537987. |
among them, clozapine is one of the atypical antipsychotics prescribed in schizophrenia wing to its blocking effect on dopamine (d2) and serotonin (5-ht |
2021-11-15 |
2023-08-13 |
rat |
| Kira Griffiths, Edward Millgate, Alice Egerton, James H MacCab. Demographic and clinical variables associated with response to clozapine in schizophrenia: a systematic review and meta-analysis. Psychological medicine. vol 51. issue 3. 2021-11-12. PMID:33602358. |
demographic and clinical variables associated with response to clozapine in schizophrenia: a systematic review and meta-analysis. |
2021-11-12 |
2023-08-13 |
human |
| Kira Griffiths, Edward Millgate, Alice Egerton, James H MacCab. Demographic and clinical variables associated with response to clozapine in schizophrenia: a systematic review and meta-analysis. Psychological medicine. vol 51. issue 3. 2021-11-12. PMID:33602358. |
clozapine is the only licensed pharmacotherapy for treatment-resistant schizophrenia. |
2021-11-12 |
2023-08-13 |
human |
| Gul Karacetin, Cagatay Ermis, Esra Bulanik Koc, Yesim Sagla. Investigating Predictors of Clozapine Response in Adolescents with Schizophrenia and Schizoaffective Disorder. Journal of child and adolescent psychopharmacology. vol 31. issue 7. 2021-11-12. PMID:34283936. |
investigating predictors of clozapine response in adolescents with schizophrenia and schizoaffective disorder. |
2021-11-12 |
2023-08-13 |
Not clear |
| Anum Iqbal Baig, Shahrzad Bazargan-Hejazi, Gul Ebrahim, Jaziel Rodriguez-Lar. Clozapine prescribing barriers in the management of treatment-resistant schizophrenia: A systematic review. Medicine. vol 100. issue 45. 2021-11-12. PMID:34766570. |
clozapine prescribing barriers in the management of treatment-resistant schizophrenia: a systematic review. |
2021-11-12 |
2023-08-13 |
Not clear |
| Anum Iqbal Baig, Shahrzad Bazargan-Hejazi, Gul Ebrahim, Jaziel Rodriguez-Lar. Clozapine prescribing barriers in the management of treatment-resistant schizophrenia: A systematic review. Medicine. vol 100. issue 45. 2021-11-12. PMID:34766570. |
currently clozapine is the only food and drug administration-approved pharmacotherapy for treatment-resistant schizophrenia but remains under-prescribed. |
2021-11-12 |
2023-08-13 |
Not clear |
| G Horvath, G Kis, G Kekesi, A Büki, L G Adlan, E Szűcs, H El Heni, S Benyh. Interaction of clozapine with metformin in a schizophrenia rat model. Scientific reports. vol 11. issue 1. 2021-11-10. PMID:34413440. |
interaction of clozapine with metformin in a schizophrenia rat model. |
2021-11-10 |
2023-08-13 |
rat |
| Srinivasan Tirupati, Tracy Gordo. Continuation of Treatment With Clozapine After an Episode of Neutropenia. Journal of clinical psychopharmacology. vol 41. issue 3. 2021-11-09. PMID:33657071. |
clozapine is the most effective in treatment-resistant schizophrenia. |
2021-11-09 |
2023-08-13 |
Not clear |
| Andrea J Stanbridge, Thomas Cranshaw, Meethu M Pau. Clozapine metabolism may be affected by Gilbert's syndrome: case report and discussion. Pharmacogenetics and genomics. vol 31. issue 9. 2021-11-09. PMID:34320604. |
a 34-year-old man with treatment-resistant schizophrenia and gilbert's syndrome was treated with clozapine and found to have unusually slow and fluctuating metabolism of clozapine, resulting in difficulty achieving a well-tolerated and stable plasma clozapine level. |
2021-11-09 |
2023-08-13 |
Not clear |