| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Theja Bhamidipati, Krishna Divadeena. Management of Clozapine Titration in the Setting of Cardiac Comorbidities. Cureus. vol 13. issue 11. 2021-12-11. PMID:34881120. |
treatment-resistant schizophrenia is commonly treated by the initiation of clozapine therapy. |
2021-12-11 |
2023-08-13 |
Not clear |
| Jisha M Lucca, Fatima M Al-Turaifi, Al-Mubayedh Safyah, Feras A Hamad Al-Awa. A Comprehensive Monitoring of Clozapine and Related Components in Clinical Practices. Saudi Arabian Scenario. Psychopharmacology bulletin. vol 51. issue 4. 2021-12-11. PMID:34887598. |
clozapine is considered as effective medication for treatment resistant schizophrenia. |
2021-12-11 |
2023-08-13 |
Not clear |
| M B Deepak, Kalra Deeksha, Rajhans Pallavi, Choudhary Hemant, Bajaj Nidhisha, Deep Rama. Clozapine Induced Hypertension and its Association with Autonomic Dysfunction. Psychopharmacology bulletin. vol 51. issue 4. 2021-12-11. PMID:34887604. |
clozapine is a second generation antipsychotic agent which is drug of choice for treatment resistant schizophrenia. |
2021-12-11 |
2023-08-13 |
Not clear |
| Sandeep Grover, Kripa Shanker Kasudhan, Naveen Murali, Amol N Patil, Smita Pattanaik, Subho Chakrabarti, Ajit Avasth. Pharmacometabolomics-guided clozapine therapy in treatment resistant schizophrenia: Preliminary exploration of future too near. Asian journal of psychiatry. vol 67. 2021-12-10. PMID:34844176. |
pharmacometabolomics-guided clozapine therapy in treatment resistant schizophrenia: preliminary exploration of future too near. |
2021-12-10 |
2023-08-13 |
Not clear |
| Sandeep Grover, Kripa Shanker Kasudhan, Naveen Murali, Amol N Patil, Smita Pattanaik, Subho Chakrabarti, Ajit Avasth. Pharmacometabolomics-guided clozapine therapy in treatment resistant schizophrenia: Preliminary exploration of future too near. Asian journal of psychiatry. vol 67. 2021-12-10. PMID:34844176. |
to study the association of clozapine pharmacometabolomics and clozapine response in asian patients with treatment-resistant schizophrenia (trs). |
2021-12-10 |
2023-08-13 |
Not clear |
| Kotaro Hatta, Shigemasa Katayama, Takuya Ishizuka, Yasuhiko Sudo, Mitsuru Nakamura, Hana Hasegawa, Atsushi Imai, Fumiyoshi Morikawa, Tatsuhiro Shimada, Fuminari Misawa, Shigeru Ozaki, Kiyoshi Fujita, Haruo Watanabe, Hiroyuki Nakamura, Naoya Sugiyam. Real-world effectiveness of antipsychotic treatments in 1011 acutely hospitalized patients with schizophrenia: A one-year follow-up study. Asian journal of psychiatry. vol 67. 2021-12-10. PMID:34875558. |
to compare the real-world effectiveness of antipsychotic treatments focusing on long-acting injectable antipsychotic medications (lais) and antipsychotic polytherapies except polytherapy involving clozapine (apec) for patients with schizophrenia. |
2021-12-10 |
2023-08-13 |
Not clear |
| Jari-Pekka Klemettilä, Anssi Solismaa, Niko Seppälä, Mari Hämäläinen, Eeva Moilanen, Esa Leinonen, Olli Kampma. Glucagon-like peptide-1 serum levels are associated with weight gain in patients treated with clozapine. Psychiatry research. vol 306. 2021-12-06. PMID:34610543. |
the aim of the present study was to test the possible role of serum glp-1 and visfatin level alterations as markers of weight gain in association with metabolic and inflammatory markers in 190 patients (109 male, 81 female) with schizophrenia on clozapine treatment. |
2021-12-06 |
2023-08-13 |
Not clear |
| Jari-Pekka Klemettilä, Anssi Solismaa, Niko Seppälä, Mari Hämäläinen, Eeva Moilanen, Esa Leinonen, Olli Kampma. Glucagon-like peptide-1 serum levels are associated with weight gain in patients treated with clozapine. Psychiatry research. vol 306. 2021-12-06. PMID:34610543. |
serum glp-1 level seems to be a marker of metabolic risk factors among men with schizophrenia on clozapine treatment. |
2021-12-06 |
2023-08-13 |
Not clear |
| Mehrnoosh Azimi Sanavi, Hamed Ghazvini, Mehryar Zargari, Hossein Ghalehnoei, Zahra Hosseini-Kha. Effects of clozapine and risperidone antipsychotic drugs on the expression of CACNA1C and behavioral changes in rat 'Ketamine model of schizophrenia. Neuroscience letters. 2021-12-06. PMID:34801642. |
effects of clozapine and risperidone antipsychotic drugs on the expression of cacna1c and behavioral changes in rat 'ketamine model of schizophrenia. |
2021-12-06 |
2023-08-13 |
rat |
| Bo Tao, Yuan Xiao, Hengyi Cao, Wenjing Zhang, Chengmin Yang, Rebekka Lencer, Qiyong Gong, Su Lu. Characteristics of the corpus callosum in chronic schizophrenia treated with clozapine or risperidone and those never-treated. BMC psychiatry. vol 21. issue 1. 2021-12-03. PMID:34715831. |
characteristics of the corpus callosum in chronic schizophrenia treated with clozapine or risperidone and those never-treated. |
2021-12-03 |
2023-08-13 |
Not clear |
| Norio Yasui-Furukori, Hiroyuki Muraoka, Naomi Hasegawa, Shinichiro Ochi, Shusuke Numata, Hikaru Hori, Akitoyo Hishimoto, Toshiaki Onitsuka, Kazutaka Ohi, Naoki Hashimoto, Tatsuya Nagasawa, Yoshikazu Takaesu, Takahiko Inagaki, Hiromi Tagata, Takashi Tsuboi, Chika Kubota, Ryuji Furihata, Jun-Ichi Iga, Hitoshi Iida, Kenichiro Miura, Junya Matsumoto, Hisashi Yamada, Koichiro Watanabe, Ken Inada, Kazutaka Shimoda, Ryota Hashimot. Association between the examination rate of treatment-resistant schizophrenia and the clozapine prescription rate in a nationwide dissemination and implementation study. Neuropsychopharmacology reports. 2021-12-02. PMID:34854260. |
association between the examination rate of treatment-resistant schizophrenia and the clozapine prescription rate in a nationwide dissemination and implementation study. |
2021-12-02 |
2023-08-13 |
Not clear |
| Norio Yasui-Furukori, Hiroyuki Muraoka, Naomi Hasegawa, Shinichiro Ochi, Shusuke Numata, Hikaru Hori, Akitoyo Hishimoto, Toshiaki Onitsuka, Kazutaka Ohi, Naoki Hashimoto, Tatsuya Nagasawa, Yoshikazu Takaesu, Takahiko Inagaki, Hiromi Tagata, Takashi Tsuboi, Chika Kubota, Ryuji Furihata, Jun-Ichi Iga, Hitoshi Iida, Kenichiro Miura, Junya Matsumoto, Hisashi Yamada, Koichiro Watanabe, Ken Inada, Kazutaka Shimoda, Ryota Hashimot. Association between the examination rate of treatment-resistant schizophrenia and the clozapine prescription rate in a nationwide dissemination and implementation study. Neuropsychopharmacology reports. 2021-12-02. PMID:34854260. |
the decision to initiate clozapine treatment should be made on an individual basis and may be closely related to the early detection of treatment-resistant schizophrenia (trs), although there is evidence that the early use of clozapine results in a better response to treatment. |
2021-12-02 |
2023-08-13 |
Not clear |
| Dylan Lahiff, Peggy Chatham, Gregory Sullivan, Adam J Fusic. Clozapine and COVID-19: A Case Report and Clinical Considerations. Current drug safety. 2021-12-01. PMID:34847849. |
the case presented here describes a patient with schizophrenia who was being managed on clozapine and who developed symptomatic covid-19 infection. |
2021-12-01 |
2023-08-13 |
Not clear |
| Francesca Regen, Nicoleta-Carmen Cosma, Lisa R Otto, Vera Clemens, Lana Saksone, Janine Gellrich, Berk Uesekes, Thi Minh Tam Ta, Eric Hahn, Michael Dettling, Isabella Heuser, Julian Hellmann-Rege. Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia. Molecular psychiatry. vol 26. issue 9. 2021-11-24. PMID:32488128. |
clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia. |
2021-11-24 |
2023-08-13 |
human |
| Francesca Regen, Nicoleta-Carmen Cosma, Lisa R Otto, Vera Clemens, Lana Saksone, Janine Gellrich, Berk Uesekes, Thi Minh Tam Ta, Eric Hahn, Michael Dettling, Isabella Heuser, Julian Hellmann-Rege. Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia. Molecular psychiatry. vol 26. issue 9. 2021-11-24. PMID:32488128. |
in patients with schizophrenia with and without clozapine treatment and matched healthy controls, at-ra serum levels and blood mrna expression of retinoid-related genes in pbmcs were quantified. |
2021-11-24 |
2023-08-13 |
human |
| Francesca Regen, Nicoleta-Carmen Cosma, Lisa R Otto, Vera Clemens, Lana Saksone, Janine Gellrich, Berk Uesekes, Thi Minh Tam Ta, Eric Hahn, Michael Dettling, Isabella Heuser, Julian Hellmann-Rege. Clozapine modulates retinoid homeostasis in human brain and normalizes serum retinoic acid deficit in patients with schizophrenia. Molecular psychiatry. vol 26. issue 9. 2021-11-24. PMID:32488128. |
our findings provide the first evidence for altered peripheral retinoid homeostasis in schizophrenia and suggest modulation of ra catabolism as a novel mechanism of action of clozapine, which may be useful in future antipsychotic drug development. |
2021-11-24 |
2023-08-13 |
human |
| Chunyan Luo, Rebekka Lencer, Na Hu, Yuan Xiao, Wenjing Zhang, Siyi Li, Su Lui, Qiyong Gon. Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated. The international journal of neuropsychopharmacology. vol 23. issue 12. 2021-11-23. PMID:32808036. |
characteristics of white matter structural networks in chronic schizophrenia treated with clozapine or risperidone and those never treated. |
2021-11-23 |
2023-08-13 |
Not clear |
| Chunyan Luo, Rebekka Lencer, Na Hu, Yuan Xiao, Wenjing Zhang, Siyi Li, Su Lui, Qiyong Gon. Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated. The international journal of neuropsychopharmacology. vol 23. issue 12. 2021-11-23. PMID:32808036. |
this study sought to explore the characteristics of white matter structural networks in chronic never-treated schizophrenia and those treated with clozapine or risperidone, and its potential association with cognitive function. |
2021-11-23 |
2023-08-13 |
Not clear |
| Amina Aissa, Rahma Jouini, Uta Ouali, Yosra Zgueb, Fethi Nacef, Zouhaier El Hechm. Clinical predictors of response to clozapine in Tunisian patients with treatment resistant schizophrenia. Comprehensive psychiatry. vol 112. 2021-11-23. PMID:34763293. |
clinical predictors of response to clozapine in tunisian patients with treatment resistant schizophrenia. |
2021-11-23 |
2023-08-13 |
human |
| Farhana Islam, Malgorzata Maciukiewicz, Natalie Freeman, Eric Huang, Arun Tiwari, Benoit H Mulsant, Bruce G Pollock, Gary Remington, James L Kennedy, Daniel J Müller, Tarek K Rajj. Contributions of cholinergic receptor muscarinic 1 and CYP1A2 gene variants on the effects of plasma ratio of clozapine/N-desmethylclozapine on working memory in schizophrenia. Journal of psychopharmacology (Oxford, England). vol 35. issue 1. 2021-11-22. PMID:33143542. |
clozapine has heterogenous efficacy in enhancing working memory in schizophrenia. |
2021-11-22 |
2023-08-13 |
Not clear |