| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kouji Fukuyama, Eishi Motomura, Motohiro Okad. Enhanced L-β-Aminoisobutyric Acid Is Involved in the Pathophysiology of Effectiveness for Treatment-Resistant Schizophrenia and Adverse Reactions of Clozapine. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238731. |
to date, both the critical mechanisms of clinical actions (effective for antipsychotic-resistant schizophrenia) and the adverse effects of clozapine remain to be elucidated. |
2023-05-27 |
2023-08-14 |
Not clear |
| Rosamaria Lombardo, Marika Ruponen, Jarkko Rautio, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Laura Calosi, Daniele Bani, Riikka Lampinen, Katja M Kanninen, Anne M Koivisto, Elina Penttilä, Heikki Löppönen, Rosario Pignatell. Development of Lyophilised Eudragit Pharmaceutics. vol 15. issue 5. 2023-05-27. PMID:37242796. |
development of lyophilised eudragit clozapine (czp) is the only effective drug in schizophrenia resistant to typical antipsychotics. |
2023-05-27 |
2023-08-14 |
Not clear |
| Can-Jun Ruan, Chuan-Yue Wang, Yan-Nan Zang, Chen-Geng Liu, Fang Dong, An-Ning Li, Zhou Wan, Wei Guo, Gang Wan. A brief history of clozapine in China with a look forward. Schizophrenia research. 2023-05-26. PMID:37236890. |
clozapine is currently used not only for treatment-refractory schizophrenia (trs), but also continues to be used in the treatment of patients with non-trs and other mental disorders; moreover, low-dose clozapine is also used in sedative-hypnotic therapy and in combination with other drugs. |
2023-05-26 |
2023-08-14 |
Not clear |
| Robert A Bittner, Andreas Reif, Mishal Quba. The ever-growing case for clozapine in the treatment of schizophrenia: an obligation for psychiatrists and psychiatry. Current opinion in psychiatry. 2023-05-24. PMID:37222196. |
the ever-growing case for clozapine in the treatment of schizophrenia: an obligation for psychiatrists and psychiatry. |
2023-05-24 |
2023-08-14 |
Not clear |
| Robert A Bittner, Andreas Reif, Mishal Quba. The ever-growing case for clozapine in the treatment of schizophrenia: an obligation for psychiatrists and psychiatry. Current opinion in psychiatry. 2023-05-24. PMID:37222196. |
clozapine remains the gold standard for treatment-resistant schizophrenia (trs). |
2023-05-24 |
2023-08-14 |
Not clear |
| Sidney Zisook, Isabel Domingues, Jason Compto. Pharmacologic Approaches to Suicide Prevention. Focus (American Psychiatric Publishing). vol 21. issue 2. 2023-05-18. PMID:37201142. |
for patients with chronic suicidality, clozapine remains the only u.s. food and drug administration (fda) approved antisuicidal medication, and its use is predominantly for patients with schizophrenia and schizoaffective disorder. |
2023-05-18 |
2023-08-14 |
Not clear |
| Hisashi Yamada, Ryota Hashimot. [Antipsychotics]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 5. 2023-05-17. PMID:37194535. |
when monotherapy of two or more antipsychotics fails to produce sufficient improvement, a diagnosis of treatment-resistant schizophrenia is made, and clozapine is used. |
2023-05-17 |
2023-08-14 |
Not clear |
| b' Vjekoslav Peitl, Antonia Pulji\\xc4\\x87, Mislav \\xc5\\xa0krobo, Sergej Nadalin, Lidija Fumi\\xc4\\x87 Dunki\\xc4\\x87, Dalibor Karlovi\\xc4\\x8. Clozapine in Treatment-Resistant Schizophrenia and Its Augmentation with Electroconvulsive Therapy in Ultra-Treatment-Resistant Schizophrenia. Biomedicines. vol 11. issue 4. 2023-05-16. PMID:37189691.' |
clozapine in treatment-resistant schizophrenia and its augmentation with electroconvulsive therapy in ultra-treatment-resistant schizophrenia. |
2023-05-16 |
2023-08-14 |
Not clear |
| b' Vjekoslav Peitl, Antonia Pulji\\xc4\\x87, Mislav \\xc5\\xa0krobo, Sergej Nadalin, Lidija Fumi\\xc4\\x87 Dunki\\xc4\\x87, Dalibor Karlovi\\xc4\\x8. Clozapine in Treatment-Resistant Schizophrenia and Its Augmentation with Electroconvulsive Therapy in Ultra-Treatment-Resistant Schizophrenia. Biomedicines. vol 11. issue 4. 2023-05-16. PMID:37189691.' |
clozapine is considered the gold standard for patients with treatment-resistant schizophrenia (trs) who have previously tried other antipsychotics at adequate doses (two or more, with at least one being atypical). |
2023-05-16 |
2023-08-14 |
Not clear |
| b' Vjekoslav Peitl, Antonia Pulji\\xc4\\x87, Mislav \\xc5\\xa0krobo, Sergej Nadalin, Lidija Fumi\\xc4\\x87 Dunki\\xc4\\x87, Dalibor Karlovi\\xc4\\x8. Clozapine in Treatment-Resistant Schizophrenia and Its Augmentation with Electroconvulsive Therapy in Ultra-Treatment-Resistant Schizophrenia. Biomedicines. vol 11. issue 4. 2023-05-16. PMID:37189691.' |
however, despite optimal treatment, a subgroup of trs patients with what is known as ultra-treatment-resistant schizophrenia (utrs) fails to respond to clozapine, which occurs in 40-70% of cases. |
2023-05-16 |
2023-08-14 |
Not clear |
| Paulo Levi Bezerra Martins, Ian Araújo Moura, Gabrielle Mendes, Vitória Cristina Almeida Flexa Ribeiro, André Arnaud, Clarissa S Gama, Michael Maes, Danielle S Macedo, Joel Porfirio Pint. Immunoinflammatory and oxidative alterations in subjects with schizophrenia under clozapine: A meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 73. 2023-05-06. PMID:37148631. |
immunoinflammatory and oxidative alterations in subjects with schizophrenia under clozapine: a meta-analysis. |
2023-05-06 |
2023-08-14 |
human |
| Yongqing Tao, Runlan Wan, Junji Wang, Qiuyi Liu, Meng Tian, Luchun Wang, Yulian Yang, Yuemeng Zou, Yuanning Luo, Famin Ke, Quan Zhou, Dandan Wang, Die Ga. Carbonized human hair derived carbon dots for detection of clozapine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 298. 2023-05-06. PMID:37148662. |
clozapine (clz) is known as the most effective antipsychotic medication for schizophrenia. |
2023-05-06 |
2023-08-14 |
human |
| Silvia Moga, Paula Simina Petric, Ana Aliana Miron, Petru Ifteni, Andreea Teodoresc. Outcome of COVID-19 mRNA Vaccination in Patients Treated With Clozapine WHO Previously Went Through SARS-COV-2 Infection. American journal of therapeutics. 2023-04-25. PMID:37097999. |
clozapine remains the gold standard for treatment-resistant schizophrenia (trs). |
2023-04-25 |
2023-08-14 |
Not clear |
| Liwei Wang, Qian Chen, Rui Ma, Bikui Zhang, Ping Yang, Ting Cao, Shimeng Jiao, Hui Chen, Chenquan Lin, Hualin Ca. Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells. Toxicology. 2023-04-22. PMID:37087062. |
clozapine is usually considered as the last resort for treatment-resistant schizophrenia (trs). |
2023-04-22 |
2023-08-14 |
Not clear |
| Abid Rizvi, Mohammed Reyazuddin, Faisal Shaa. Low Dose Clozapine in Early Onset Resistant Schizophrenia: Case Report and Two Year Follow-up. Journal of the American Academy of Child and Adolescent Psychiatry. 2023-04-19. PMID:37075891. |
low dose clozapine in early onset resistant schizophrenia: case report and two year follow-up. |
2023-04-19 |
2023-08-14 |
Not clear |
| Deepak K Sarpal, Kangho Suh, Kaiqi Bian, Pingjui Ko, Jessica M Gannon, Peter Jhon, K N Roy Chengapp. Community-Based Service Use After Clozapine Treatment: A Mirror-Image Analysis of Public Claims Data. Psychiatric services (Washington, D.C.). 2023-04-05. PMID:37016827. |
the authors examined changes in use of community-based services after clozapine treatment among a sample of 163 patients with schizophrenia by using public claims data in allegheny county, pennsylvania. |
2023-04-05 |
2023-08-14 |
Not clear |
| Carla Lou Morgenroth, Philipp Kleymann, Stephan Ripke, Swapnil Awasthi, Elias Wagner, Tatiana Oviedo-Salcedo, Cynthia Okhuijsen-Pfeifer, Jurjen J Luykx, Marte Z van der Horst, Alkomiet Hasan, Felix Bermpohl, Stefan Gutwinski, Stefanie Schreite. Polygenetic risk scores and phenotypic constellations of obsessive-compulsive disorder in clozapine-treated schizophrenia. European archives of psychiatry and clinical neuroscience. 2023-04-05. PMID:37020043. |
obsessive-compulsive symptoms (ocs) are frequently observed in individuals with schizophrenia (scz) treated with clozapine (clz). |
2023-04-05 |
2023-08-14 |
human |
| Tuğçe Saltoğlu, Bedirhan Şenol, Guray Ko. Non-convulsive Status Epilepticus as a Complication of Electroconvulsive Therapy: A Case Report and Review of the Literature. Cureus. vol 15. issue 3. 2023-04-03. PMID:37009391. |
here, we present a 29-year-old patient with no previous neurological disease and a history of schizophrenia and refractory psychosis on clozapine; nonconvulsive status epilepticus was detected in the eeg after ect. |
2023-04-03 |
2023-08-14 |
Not clear |
| Jie Lisa Ji, Todd Lencz, Juan Gallego, Nicholas Neufeld, Aristotle Voineskos, Anil Malhotra, Alan Anticevi. Informing individualized multi-scale neural signatures of clozapine response in patients with treatment-refractory schizophrenia. medRxiv : the preprint server for health sciences. 2023-03-30. PMID:36993630. |
informing individualized multi-scale neural signatures of clozapine response in patients with treatment-refractory schizophrenia. |
2023-03-30 |
2023-08-14 |
Not clear |
| Jie Lisa Ji, Todd Lencz, Juan Gallego, Nicholas Neufeld, Aristotle Voineskos, Anil Malhotra, Alan Anticevi. Informing individualized multi-scale neural signatures of clozapine response in patients with treatment-refractory schizophrenia. medRxiv : the preprint server for health sciences. 2023-03-30. PMID:36993630. |
clozapine is currently the only antipsychotic with demonstrated efficacy in treatment-refractory schizophrenia (trs). |
2023-03-30 |
2023-08-14 |
Not clear |