| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oliver Freudenreich, David C Henderson, Jared P Walsh, Melissa A Culhane, Donald C Gof. Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial. Schizophrenia research. vol 92. issue 1-3. 2007-07-03. PMID:17321111. |
risperidone augmentation of clozapine in refractory schizophrenia has theoretical but only inconsistent support from clinical trials. |
2007-07-03 |
2023-08-12 |
Not clear |
| Wiesław J Cubała, Hubert M Wichowicz, Jerzy Landowsk. Refractory schizophrenia treated with clozapine combined with zuclopenthixol. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 3. 2007-06-26. PMID:17258371. |
refractory schizophrenia treated with clozapine combined with zuclopenthixol. |
2007-06-26 |
2023-08-12 |
Not clear |
| Robert Kerwi. When should clozapine be initiated in schizophrenia?: Some arguments for and against earlier use of clozapine. CNS drugs. vol 21. issue 4. 2007-06-26. PMID:17381182. |
when should clozapine be initiated in schizophrenia? |
2007-06-26 |
2023-08-12 |
Not clear |
| Robert Kerwi. When should clozapine be initiated in schizophrenia?: Some arguments for and against earlier use of clozapine. CNS drugs. vol 21. issue 4. 2007-06-26. PMID:17381182. |
this article considers some of the arguments for unshackling clozapine from its current license for schizophrenia (its superiority overall in treatment-resistant schizophrenia, its potential for use in first-episode patients, and its anti-suicidal potential), and tries to synthesise these into some of the national guidelines available for the treatment of schizophrenia. |
2007-06-26 |
2023-08-12 |
Not clear |
| Yasin Genç, Ender Taner, Selcuk Candansaya. Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Advances in therapy. vol 24. issue 1. 2007-06-22. PMID:17526456. |
comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. |
2007-06-22 |
2023-08-12 |
Not clear |
| Yasin Genç, Ender Taner, Selcuk Candansaya. Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Advances in therapy. vol 24. issue 1. 2007-06-22. PMID:17526456. |
clozapine has long been the gold standard for treatment of patients with treatment-resistant schizophrenia; however, some patients are only partially responsive to clozapine treatment. |
2007-06-22 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Stephanie Feldman, Yang Yu, Robert P McMahon, Charles M Richardso. Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. The Psychiatric quarterly. vol 77. issue 1. 2007-06-14. PMID:16397757. |
adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. |
2007-06-14 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert R Conley, Stephanie Feldman, Yang Yu, Robert P McMahon, Charles M Richardso. Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. The Psychiatric quarterly. vol 77. issue 1. 2007-06-14. PMID:16397757. |
this retrospective study examined adjunct divalproex (n = 15) or lithium (n = 9) in treatment-resistant schizophrenia patients added to clozapine and compared to clozapine monotherapy (n = 25). |
2007-06-14 |
2023-08-12 |
Not clear |
| Gaetana Migliardi, Concetta D'Arrigo, Vincenza Santoro, Antonio Bruno, Lara Cortese, Domenica Campolo, Massimo Cacciola, Edoardo Spin. Effect of topiramate on plasma concentrations of clozapine, olanzapine, risperidone, and quetiapine in patients with psychotic disorders. Clinical neuropharmacology. vol 30. issue 2. 2007-06-13. PMID:17414943. |
to investigate the effect of topiramate on the steady-state plasma concentrations of the second-generation antipsychotics--clozapine, olanzapine, risperidone, and quetiapine--in patients with schizophrenia or bipolar disorder. |
2007-06-13 |
2023-08-12 |
Not clear |
| Francisco J Diaz, Tulia E Rivera, Richard C Josiassen, Jose de Leo. Individualizing drug dosage by using a random intercept linear model. Statistics in medicine. vol 26. issue 9. 2007-05-31. PMID:16847902. |
computations are illustrated for clozapine, an antipsychotic drug used to treat patients with severe schizophrenia. |
2007-05-31 |
2023-08-12 |
Not clear |
| Neil D Woodward, Karu Jayathilake, Herbert Y Meltze. COMT val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia. Schizophrenia research. vol 90. issue 1-3. 2007-05-30. PMID:17123785. |
comt val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia. |
2007-05-30 |
2023-08-12 |
Not clear |
| Sarah M Turgeon, Virginia C Hulic. Differential effects of acute and subchronic clozapine and haloperidol on phencyclidine-induced decreases in voluntary sucrose consumption in rats. Pharmacology, biochemistry, and behavior. vol 86. issue 3. 2007-05-22. PMID:17320157. |
given that atypical antipsychotics have been shown to ameliorate negative symptoms of schizophrenia more effectively than typical neuroleptics, this effect should be reversed by clozapine but not haloperidol. |
2007-05-22 |
2023-08-12 |
rat |
| Edward D Levin, D Patrick Caldwell, Charles Perrau. Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response. Pharmacology, biochemistry, and behavior. vol 86. issue 3. 2007-05-22. PMID:17355891. |
this may be relevant to the action of clozapine in attenuating sensory gating deficits in schizophrenia and may point to new avenues of treatment for sensory modulation disorders in which there is excessive tactile response. |
2007-05-22 |
2023-08-12 |
rat |
| Robert E McCu. Clozapine improves symptoms but not quality of life compared with other second-generation antipsychotics in people with treatment resistant schizophrenia. Evidence-based mental health. vol 10. issue 2. 2007-05-22. PMID:17459988. |
clozapine improves symptoms but not quality of life compared with other second-generation antipsychotics in people with treatment resistant schizophrenia. |
2007-05-22 |
2023-08-12 |
Not clear |
| Andrew J Goudie, Gillian D Cooper, Jon C Cole, Harry R Sumnal. Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats. Journal of psychopharmacology (Oxford, England). vol 21. issue 2. 2007-05-15. PMID:17329298. |
our findings, in conjunction with other actions of cyproheptadine -- induction of weight gain, alleviation of clozapine withdrawal, anxiolytic actions, alleviation of 'typical' apd-induced motoric side effects, and some preliminary clinical findings -- suggest that further study of cyproheptadine in conjunction with a 'typical' apd for the possible treatment of schizophrenia is merited at both pre-clinical and clinical levels. |
2007-05-15 |
2023-08-12 |
rat |
| Maria Bjarnadottir, Dinah L Misner, Sascha Haverfield-Gross, Silas Bruun, Vignir G Helgason, Hreinn Stefansson, Arnar Sigmundsson, David R Firth, Berit Nielsen, Ragnheidur Stefansdottir, Thomas J Novak, Kari Stefansson, Mark E Gurney, Thorkell Andresso. Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 17. 2007-05-15. PMID:17460065. |
furthermore, we showed that nrg1+/- mutant mice display behavioral abnormalities that are reversed by clozapine, an atypical antipsychotic drug used for the treatment of schizophrenia. |
2007-05-15 |
2023-08-12 |
mouse |
| Lu-xian Lü, Su-qin Guo, Wei Chen, Qiang Li, Jun Cheng, Jing-hua Gu. [Effect of clozapine and risperidone on serum cytokine levels in patients with first-episode paranoid schizophrenia]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. vol 24. issue 11. 2007-05-09. PMID:15567770. |
[effect of clozapine and risperidone on serum cytokine levels in patients with first-episode paranoid schizophrenia]. |
2007-05-09 |
2023-08-12 |
Not clear |
| Yu-Tao Xiang, Yong-Zhen Weng, Chi-Ming Leung, Wai-Kwong Tang, Gabor Sandor Ungvar. Clinical correlates of clozapine prescription for schizophrenia in China. Human psychopharmacology. vol 22. issue 1. 2007-05-02. PMID:17191268. |
clinical correlates of clozapine prescription for schizophrenia in china. |
2007-05-02 |
2023-08-12 |
Not clear |
| Yu-Tao Xiang, Yong-Zhen Weng, Chi-Ming Leung, Wai-Kwong Tang, Gabor Sandor Ungvar. Clinical correlates of clozapine prescription for schizophrenia in China. Human psychopharmacology. vol 22. issue 1. 2007-05-02. PMID:17191268. |
few studies have investigated the prescription patterns of clozapine in outpatients with schizophrenia in china. |
2007-05-02 |
2023-08-12 |
Not clear |
| Pietro Gareri, Pasquale De Fazio, Salvatore De Fazio, Norma Marigliano, Guido Ferreri Ibbadu, Giovambattista De Sarr. Adverse effects of atypical antipsychotics in the elderly: a review. Drugs & aging. vol 23. issue 12. 2007-05-01. PMID:17154659. |
use of clozapine, for example, is limited by the risk of agranulocytosis, whereas this is not a disadvantage of olanzapine, risperidone, quetiapine and, more recently, ziprasidone, which are being widely used with good results in schizophrenia. |
2007-05-01 |
2023-08-12 |
Not clear |